10X GENOMICS, INC., 10-K filed on 2/13/2026
Annual Report
v3.25.4
Cover Page - USD ($)
$ in Billions
12 Months Ended
Dec. 31, 2025
Jan. 31, 2026
Jun. 30, 2025
Entity Information [Line Items]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2025    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-39035    
Entity Registrant Name 10x Genomics, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 45-5614458    
Entity Address, Address Line One 6230 Stoneridge Mall Road    
Entity Address, City or Town Pleasanton    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 94588    
City Area Code (925)    
Local Phone Number 401-7300    
Title of 12(b) Security Class A common stock, par value $0.00001 per share    
Trading Symbol TXG    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Public Float     $ 1.3
Documents Incorporated by Reference
Portions of the registrant’s Definitive Proxy Statement relating to the registrant’s 2026 Annual Meeting of Shareholders are incorporated by reference into Part III of this Annual Report on Form 10-K where indicated. Such Definitive Proxy Statement will be filed with the Securities and Exchange Commission within 120 days after the end of the registrant’s fiscal year ended December 31, 2025.
   
Amendment Flag false    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY    
Entity Central Index Key 0001770787    
Common Class A      
Entity Information [Line Items]      
Entity Common Stock, Shares Outstanding   117,673,382  
Common Class B      
Entity Information [Line Items]      
Entity Common Stock, Shares Outstanding   10,078,872  
v3.25.4
Audit Information
12 Months Ended
Dec. 31, 2025
Audit Information [Abstract]  
Auditor Firm ID 42
Auditor Name Ernst & Young LLP
Auditor Location San Jose, California
v3.25.4
Consolidated Balance Sheets - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Current assets:    
Cash and cash equivalents $ 473,966 $ 344,067
Marketable securities 49,443 49,335
Accounts receivable, net 47,013 87,862
Inventory 56,341 83,107
Other receivables 35,480 606
Prepaid expenses and other current assets 22,208 19,410
Total current assets 684,451 584,387
Property and equipment, net 226,711 252,648
Operating lease right-of-use assets 60,450 57,290
Goodwill 4,511 4,511
Intangible assets, net 62,329 15,671
Other noncurrent assets 2,913 4,129
Total assets 1,041,365 918,636
Current liabilities:    
Accounts payable 12,733 12,909
Accrued compensation and related benefits 42,500 33,615
Accrued expenses and other current liabilities 39,971 41,165
Deferred revenue 23,902 20,658
Operating lease liabilities 10,985 9,286
Contingent consideration, current 23,363 0
Total current liabilities 153,454 117,633
Contingent consideration, noncurrent 1,237 0
Operating lease liabilities, noncurrent 73,376 73,327
Deferred revenue, noncurrent 10,501 12,513
Other noncurrent liabilities 6,471 5,029
Total liabilities 245,039 208,502
Commitments and contingencies (Note 7)
Stockholders' equity:    
Preferred stock, $0.00001 par value; 100,000,000 shares authorized, no shares issued or outstanding as of December 31, 2025 and 2024 0 0
Common stock, $0.00001 par value; 1,100,000,000 shares authorized (Class A 1,000,000,000, Class B 100,000,000); 127,691,329 (Class A 117,612,457, Class B 10,078,872) and 122,291,837 (Class A 108,235,004, Class B 14,056,833) shares issued and outstanding as of December 31, 2025 and 2024, respectively 2 2
Additional paid-in capital 2,306,690 2,177,672
Accumulated deficit (1,510,591) (1,467,047)
Accumulated other comprehensive income (loss) 225 (493)
Total stockholders’ equity 796,326 710,134
Total liabilities and stockholders’ equity $ 1,041,365 $ 918,636
v3.25.4
Consolidated Balance Sheets (Parenthetical) - $ / shares
Dec. 31, 2025
Dec. 31, 2024
Preferred stock, par value (in dollars per share) $ 0.00001 $ 0.00001
Preferred stock, shares authorized (in shares) 100,000,000 100,000,000
Preferred stock, shares issued (in shares) 0 0
Preferred stock, shares outstanding (in shares) 0 0
Common stock, par value (in dollars per share) $ 0.00001 $ 0.00001
Common stock, shares authorized (in shares) 1,100,000,000 1,100,000,000
Common stock, shares issued (in shares) 127,691,329 122,291,837
Common stock, shares outstanding (in shares) 127,691,329 122,291,837
Common Class A    
Common stock, par value (in dollars per share) $ 0.00001  
Common stock, shares authorized (in shares) 1,000,000,000 1,000,000,000
Common stock, shares issued (in shares) 117,612,457 108,235,004
Common stock, shares outstanding (in shares) 117,612,457 108,235,004
Common Class B    
Common stock, par value (in dollars per share) $ 0.00001  
Common stock, shares authorized (in shares) 100,000,000 100,000,000
Common stock, shares issued (in shares) 10,078,872 14,056,833
Common stock, shares outstanding (in shares) 10,078,872 14,056,833
v3.25.4
Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenue $ 642,823 $ 610,785 $ 618,727
Cost of products and services revenue 198,942 196,303 209,414
Gross profit 443,881 414,482 409,313
Operating expenses:      
Research and development 238,632 264,698 270,332
Selling, general and administrative 316,134 344,343 343,330
Gain on settlement (49,900) 0 0
In-process research and development 0 0 60,980
Total operating expenses 504,866 609,041 674,642
Loss from operations (60,985) (194,559) (265,329)
Other income (expense):      
Interest income 20,048 18,930 16,885
Interest expense 0 (4) (33)
Other income (expense), net 1,030 (2,067) (286)
Total other income 21,078 16,859 16,566
Loss before provision for income taxes (39,907) (177,700) (248,763)
Provision for income taxes 3,637 4,927 6,336
Net loss $ (43,544) $ (182,627) $ (255,099)
Net loss per share, basic (in dollars per share) $ (0.35) $ (1.52) $ (2.18)
Net loss per share, diluted (in dollars per share) $ (0.35) $ (1.52) $ (2.18)
Weighted-average shares used to compute net loss per share, basic (in shares) 124,749,885 120,451,550 117,165,036
Weighted-average shares used to compute net loss per share, diluted (in shares) 124,749,885 120,451,550 117,165,036
Products and services revenue      
Revenue $ 596,688 $ 610,464 $ 618,727
License and royalty revenue      
Revenue $ 46,135 $ 321 $ 0
v3.25.4
Consolidated Statements of Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Statement of Comprehensive Income [Abstract]      
Net loss $ (43,544) $ (182,627) $ (255,099)
Other comprehensive income (loss), net of tax:      
Unrealized gains (losses) on available-for-sale marketable securities (6) 206 2,210
Realized loss on available-for-sale marketable securities reclassified into net loss 0 3 1,718
Foreign currency translation adjustment 724 (273) (22)
Other comprehensive income (loss), net of tax 718 (64) 3,906
Comprehensive loss $ (42,826) $ (182,691) $ (251,193)
v3.25.4
Consolidated Statements of Stockholders’ Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Common Class A
Common Class A
Common Stock
Common Class A
Additional Paid-in Capital
Beginning balance (in shares) at Dec. 31, 2022   115,195,009            
Beginning balance at Dec. 31, 2022 $ 805,743 $ 2 $ 1,839,397 $ (1,029,321) $ (4,335)      
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuance of Class A common stock related to equity awards (in shares)             3,900,353  
Issuance of Class A common stock related to equity awards           $ 19,483   $ 19,483
Stock-based compensation 167,010   167,010          
Net loss (255,099)     (255,099)        
Other comprehensive income (loss) 3,906       3,906      
Ending balance (in shares) at Dec. 31, 2023   119,095,362            
Ending balance at Dec. 31, 2023 741,043 $ 2 2,025,890 (1,284,420) (429)      
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuance of Class A common stock related to equity awards (in shares)             3,196,475  
Issuance of Class A common stock related to equity awards           10,914   10,914
Stock-based compensation 140,868   140,868          
Net loss (182,627)     (182,627)        
Other comprehensive income (loss) (64)       (64)      
Ending balance (in shares) at Dec. 31, 2024   122,291,837            
Ending balance at Dec. 31, 2024 710,134 $ 2 2,177,672 (1,467,047) (493)      
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuance of Class A common stock related to equity awards (in shares)             4,299,500  
Issuance of Class A common stock related to equity awards           $ 6,803   $ 6,803
Issuance of Class A common stock for acquisition of assets (in shares)   1,099,992            
Issuance of Class A common stock for acquisition of assets 13,541   13,541          
Stock-based compensation 108,674   108,674          
Net loss (43,544)     (43,544)        
Other comprehensive income (loss) 718       718      
Ending balance (in shares) at Dec. 31, 2025   127,691,329            
Ending balance at Dec. 31, 2025 $ 796,326 $ 2 $ 2,306,690 $ (1,510,591) $ 225      
v3.25.4
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Operating activities:      
Net loss $ (43,544) $ (182,627) $ (255,099)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:      
Stock-based compensation expense 109,118 140,749 166,950
Depreciation and amortization 36,199 35,879 35,512
Asset and lease impairment charges 814 3,054 9,845
ROU assets impairment due to restructuring 1,253 0 0
Amortization of right-of-use assets 7,617 7,829 8,107
Fair value adjustments on contingent consideration 1,407 0 0
Realized loss on marketable securities 0 3 1,718
Other (1,753) 523 427
Changes in operating assets and liabilities:      
Accounts receivable 41,314 26,951 (10,613)
Other receivables (34,874) 0 0
Inventory 27,953 (9,777) 7,871
Prepaid expenses and other current assets (2,343) (1,901) (2,429)
Other noncurrent assets 689 (1,084) (678)
Accounts payable (2,126) (3,354) (6,017)
Accrued compensation and other related benefits 7,647 3,654 (2,637)
Deferred revenue 746 11,209 10,932
Accrued expenses and other current liabilities (5,153) (12,736) 28,301
Operating lease liability (10,310) (12,484) (8,671)
Other noncurrent liabilities 1,396 776 1,284
Net cash provided by (used in) operating activities 136,050 6,664 (15,197)
Investing activities:      
Proceeds from maturities of marketable securities 125,200 25,782 82,825
Proceeds from sales of marketable securities 0 3,856 100,191
Purchase of marketable securities (123,435) (48,876) 0
Asset acquisition, net (9,268) 0 0
Purchases of property and equipment (5,935) (12,393) (48,601)
Purchase of intangible assets 0 (1,000) (923)
Net cash (used in) provided by investing activities (13,438) (32,631) 133,492
Financing activities:      
Issuance of common stock from exercise of stock options and employee stock purchase plan purchases 6,803 10,914 19,483
Payments on technology license financing arrangement 0 0 (5,814)
Net cash provided by financing activities 6,803 10,914 13,669
Effect of exchange rate changes on cash and cash equivalents 484 (164) (33)
Net increase (decrease) in cash and cash equivalents 129,899 (15,217) 131,931
Cash, cash equivalents and restricted cash at beginning of year 344,067 359,284 227,353
Cash and cash equivalents at end of year 473,966 344,067 359,284
Supplemental disclosures of cash flow information:      
Cash paid for interest 0 0 436
Cash paid for taxes 2,391 5,641 4,927
Noncash investing and financing activities      
Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities 215 1,351 3,324
Right-of-use assets obtained in exchange for new operating lease liabilities 11,397 0 6,518
Common stock issued for acquisition of assets $ 13,541 $ 0 $ 0
v3.25.4
Description of Business and Basis of Presentation
12 Months Ended
Dec. 31, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Description of Business and Basis of Presentation Description of Business and Basis of Presentation
Organization and Description of Business
10x Genomics, Inc. (the “Company”) is a life sciences technology company focused on building innovative products and solutions to interrogate, understand and master biology. The Company’s integrated research solutions include the Company’s single cell instruments, which include the Company’s Chromium instruments, and the Company’s Spatial instruments, which include the Company’s Visium CytAssist and Xenium Analyzer instruments, and the Company’s consumables, which include proprietary microfluidic chips, slides, reagents and other consumables for the Company’s Chromium, Visium and Xenium solutions. The Company bundles its software with these products to guide customers through the workflow, from sample preparation through analysis and visualization. Customers purchase instruments and consumables from the Company for use in their experiments. The Company was incorporated in the state of Delaware in July 2012 and began commercial and manufacturing operations and selling its instruments and consumables in 2015. The Company is headquartered in Pleasanton, California and has wholly-owned subsidiaries in Asia, Europe, Oceania and North America.
Basis of Presentation
The consolidated financial statements, which include the Company’s accounts and the accounts of its wholly-owned subsidiaries, are prepared in accordance with U.S. generally accepted accounting principles (or “GAAP”). All intercompany transactions and balances have been eliminated.
Reclassification
Amounts related to license and royalty revenue in the consolidated statements of operations for the years ended December 31, 2024 and 2023 have been reclassified to conform to the current presentation. Amounts related to accretion of discount and amortization of premium on marketable securities in the consolidated statements of operations for the years ended December 31, 2024 and 2023 have been reclassified to conform to the current presentation. Amounts related to other receivables in the consolidated balance sheet as of December 31, 2024 have been reclassified to conform to the current presentation.
v3.25.4
Summary of Significant Accounting Policies
12 Months Ended
Dec. 31, 2025
Accounting Policies [Abstract]  
Summary of Significant Accounting Policies Summary of Significant Accounting Policies
Use of Estimates
The preparation of financial statements in conformity with GAAP requires management to make judgments, estimates and assumptions that affect the reported amounts of assets and liabilities at the date of the financial statements, disclosure of contingent liabilities, and the reported amounts of revenue and expense. These judgments, estimates and assumptions are used for, but not limited to, revenue recognition, inventory valuation and write-downs, accounting for asset and business acquisitions, the valuation of stock-based compensation awards and remeasurement of contingent consideration. The Company bases its estimates on various factors and information, which may include, but are not limited to, history and prior experience, the Company’s forecasts and future plans, current economic conditions and information from third-party professionals that management believes to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities and recorded amounts of expenses that are not readily apparent from other sources. To the extent there are material differences between the Company’s estimates and the actual results, the Company’s future consolidated results of operation may be affected.
Segment Information
The Company operates as a single operating segment. The Company’s chief operating decision maker (“CODM”), its Chief Executive Officer, manages the Company’s operations on a consolidated basis for the purposes of allocating resources, making operating decisions and evaluating financial performance. The measures of profitability and significant segment expenses reviewed by the CODM are consistent with the presentation and disclosure in these consolidated financial statements.
Cash and Cash Equivalents
The Company considers all highly liquid investments with an original maturity of three months or less from the date of purchase to be cash equivalents. Cash equivalents consist of amounts invested in money market funds and are stated at fair value.
Marketable Securities
The Company designates investments in debt securities as available-for-sale. Available-for-sale debt securities with original maturities of three months or less from the date of purchase are classified within cash and cash equivalents. Available-for-sale debt securities with original maturities longer than three months are available to fund current operations and are classified as marketable securities, within current assets on the balance sheet. Available-for-sale debt securities are reported at fair value with the related unrealized gains and losses included in "Accumulated other comprehensive income (loss)," a component of stockholders’ equity, net of tax. Realized gains (losses) on the sale of marketable securities are determined using the specific-identification method and recorded in “Other income (expense), net,” in the Company’s consolidated statements of operations.
The available-for-sale debt securities are subject to a periodic impairment review. For investments in an unrealized loss position, the Company determines whether a credit loss exists by considering information about the collectability of the instrument, current market conditions and reasonable and supportable forecasts of economic conditions. The Company recognizes an allowance for credit losses, up to the amount of the unrealized loss when appropriate, and writes down the amortized cost basis of the investment if it is more likely than not that the Company will be required or will intend to sell the investment before recovery of its amortized cost basis. Allowances for credit losses and write-downs are recognized in “Other income (expense), net,” and unrealized losses not related to credit losses are recognized in “Other comprehensive income (loss).” There are no allowances for credit losses for the periods presented.
Fair Value of Financial Instruments
Cash equivalents are comprised of money market funds which are classified as Level 1 in the fair value hierarchy. Assets recorded at fair value on a recurring basis in the balance sheets are categorized based upon the level of judgment associated with the inputs used to measure their fair values. Fair value is defined as the exchange price that would be received for an asset in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. The authoritative guidance on fair value measurements establishes a three-tier fair value hierarchy for disclosure of fair value measurements as follows:
Level 1 - Inputs are unadjusted, quoted prices in active markets for identical assets or liabilities at the measurement date;
Level 2 - Inputs are observable, unadjusted quoted prices in active markets for similar assets or liabilities, unadjusted quoted prices for identical or similar assets or liabilities in markets that are not active, or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the related assets or liabilities; and
Level 3 - Unobservable inputs that are significant to the measurement of the fair value of the assets or liabilities that are supported by little or no market data.
The Company’s financial instruments consist of Level 1 and Level 2 assets. Where quoted prices are available in an active market, securities are classified as Level 1. Money market funds are classified as Level 1. Level 2 assets include corporate bonds, asset-backed securities, commercial paper, U.S. Government Treasury and agency securities, and debt securities in government-sponsored entities based upon quoted market prices for similar movements in active markets, quoted prices for identical or similar instruments in markets that are not active and model-based valuation techniques for which all significant inputs are observable in the market or can be corroborated by observable market data for substantially the full term of the assets. Where applicable, these models project future cash flows and discount the future amounts to a present value using market-based observable inputs obtained from various third party-data providers, including but not limited to, benchmark yields, interest rate curves, reported trades, broker/dealer quotes and reference data.
The Company measures contingent consideration related to the Company’s acquisition of Scale Biosciences, Inc. (“Scale Bio”) at fair value on a recurring basis. Refer to Note 4, Acquisitions, for additional details regarding the acquisition. The contingent consideration is valued using a probability-weighted discounted cash flow approach, which reflects management’s estimates of future outcomes, timing of payments and discount rates. Because these inputs involve significant judgment, the fair value measurement are classified as Level 3 within the fair value hierarchy.
Accounts Receivable, Net
Accounts receivable consist of amounts due from customers for the sales of products and services. The Company reviews its accounts receivable and provides allowances of specific amounts if collectability is no longer reasonably assured based on historical experience and specific customer collection issues. As of December 31, 2025 and 2024, the allowance for doubtful accounts was $0.1 million for both periods.
Business Concentrations
The Company’s instruments are mostly assembled and tested by third party contract manufacturers in Asia and the United States. The Company’s agreement with the contract manufacturers contains purchase commitments. In addition, the Company relies on several suppliers for key components for its reagent kits. A significant disruption in the operations of the contract manufacturers or suppliers may impact the production of the Company’s products for a substantial period of time, which could have a material adverse effect on its business, financial condition and results of operations.
Concentrations
Financial instruments that potentially subject the Company to credit risk consist of cash equivalents, marketable securities, accounts receivable and other receivables. The Company’s cash and cash equivalents held with large financial institutions in the United States and deposits exceed the Federal Deposit Insurance Corporation’s insurance limit. The Company performs periodic evaluations of the risks associated with its investments and the relative credit standing of these financial institutions.
The Company performs ongoing credit evaluations of its customers’ financial condition. The Company does not require collateral from its customers but may require upfront payments from certain customers. The Company has not experienced material credit losses to date. For the years ended December 31, 2025, 2024, and 2023, no single customer represented more than 10% of revenue. No customer or distributor represented more than 10% of the Company’s outstanding accounts receivable as of December 31, 2025 or 2024.
Inventory
Inventory is recorded at the lower of cost, determined on a first-in, first-out basis, or net realizable value. The Company uses judgment to analyze and determine if the composition of its inventory is obsolete, slow-moving, unsalable or otherwise carried above the net realizable value and frequently reviews such determinations. The Company writes down specifically identified unusable, obsolete, slow-moving or known unsalable inventory and inventory otherwise carried above the net realizable value in the period that it is first recognized by using a number of factors including product expiration dates, open and unfulfilled orders and sales forecasts. Net realizable value is determined using the estimated selling prices in the ordinary course of business, less reasonably predictable costs of completion, disposal and transportation. Any write-down of its inventory to net realizable value establishes a new cost basis and will be maintained even if certain circumstances suggest that the inventory is recoverable in subsequent periods. Costs associated with the write-down of inventory are recorded to cost of revenue on the Company’s consolidated statements of operations.
Leases
The Company determines if an arrangement is or contains a lease at inception by assessing whether the arrangement contains an identified asset and whether it has the right to control the identified asset. Right-of-use (“ROU”) assets represent the Company’s right to use an underlying asset for the lease term and lease liabilities represent the Company’s obligation to make lease payments arising from the lease. Lease liabilities are recognized at the lease commencement date based on the present value of future lease payments over the lease term. ROU assets are based on the measurement of the lease liability and also include any lease payments made prior to or on lease commencement and exclude lease incentives and initial direct costs incurred, as applicable.
The Company uses its incremental borrowing rate based on the information available at the lease commencement date in determining the present value of future lease payments. The Company gives consideration to its credit risk, term of the lease and total lease payments and adjusts for the impacts of collateral, as necessary, when calculating its incremental borrowing rates. The lease terms may include options to extend or terminate the lease when the Company is reasonably certain it will exercise such options. Lease costs for the Company’s operating leases are recognized on a straight-line basis within operating expenses and costs of goods sold over the reasonably assured lease term.
The Company evaluates ROU assets related to leases for indicators of impairment whenever events or changes in circumstances indicate that the carrying amount of an ROU asset may not be recoverable. This evaluation is performed in a manner consistent with the Company’s impairment assessment for long-lived assets. When a decision has been made to sublease that space, the Company evaluates the asset for impairment and recognize the associated impact to the ROU asset and related expense, if applicable. The evaluation is performed at the lowest level of identifiable cash flows for an asset group. Undiscounted cash flows expected to be generated by the related ROU assets are estimated over the ROU assets’ useful lives. If the evaluation indicates that the carrying amount of the ROU assets may not be recoverable, any potential impairment is measured based upon the fair value of the related ROU asset or asset group as determined by appropriate valuation techniques. During the year ended December 31, 2025, the Company recognized an impairment loss related to the ROU assets associated with the leased facility acquired as part of the Scale Bio acquisition. Refer to the Impairment of Long-Lived Assets section below and Note 7, Commitments and Contingencies - Lease Agreements, for further details.
The Company has elected to not separate lease and non-lease components for any leases within its existing classes of assets and, as a result, accounts for any lease and non-lease components as a single lease component. The Company has also elected to not apply the recognition requirement to any leases within its existing classes of assets with a term of 12 months or less.
Property and Equipment, Net
Property and equipment is stated at cost, net of accumulated depreciation. Depreciation is computed using the straight-line method based on the estimated useful lives of the following assets:
Useful Life (Years)
Building3-40
Laboratory equipment and machinery 2-5
Computer equipment2-5
Furniture and fixtures3
Leasehold improvements3-10
Acquisitions of Intellectual Property
The Company evaluates acquisitions of assets and other similar transactions to assess whether or not the transaction should be accounted for as a business combination or asset acquisition by first applying a screen test to determine if substantially all of the fair value of the gross assets acquired is concentrated in a single identifiable asset or group of similar identifiable assets. If the screen test is met, the transaction is accounted for as an asset acquisition. If the screen test is not met, further determination is required as to whether or not the Company has acquired inputs and processes that have the ability to create outputs, which would meet the requirements of a business.
The Company accounts for asset acquisition under Accounting Standards Codification, Business Combinations, Topic 805, Subtopic 50, which requires the acquiring entity in an asset acquisition to recognize net assets based on the cost to the acquiring entity on a relative fair value basis, which includes transaction costs in addition to consideration given. Goodwill is not recognized in an asset acquisition and any excess consideration transferred over the fair value of the net assets acquired is allocated to the non-monetary identifiable assets based on relative fair values.
If the Company has the option to pay in equity for contingent consideration related to the acquisition, a liability is recorded in accordance with the guidance of ASC 480, Distinguishing Liabilities from Equity. The contingent consideration is recorded at fair value at inception and is revalued on a quarterly basis for any significant adjustments and recognized in the Company’s consolidated statements of operations in “Other income (expense), net.”
Impairment of Long-Lived Assets
The Company evaluates long-lived assets, such as property and equipment and intangible assets, for impairment whenever events or changes in circumstances indicate that the carrying value of an asset may not be recoverable. If indicators of impairment exist and the undiscounted future cash flows that the assets are expected to generate are less than the carrying value of the assets, the Company reduces the carrying amount of the assets to their estimated fair values based on a discounted cash flow approach or, when available and appropriate, to comparable market values. The Company recorded impairment charges of $2.1 million, $3.1 million and $9.8 million primarily relating to computer equipment, software, ROU assets, and intangible assets during the years ended December 31, 2025, 2024 and 2023, respectively. Refer to Note 5, Other Financial Statement Information, for further details.
Substantially all the Company’s long-lived assets are located in the United States.
Product Warranties
The Company generally provides a one-year warranty on its instruments. The Company reviews its exposure to estimated warranty obligations associated with instrument sales and establishes an accrual based on historical product failure rates and actual warranty costs incurred. This expense is recorded as a component of cost of revenue in the consolidated statements of operations.
Deferred Revenue
Deferred revenue consists of payments received in advance of revenue recognition primarily related to instrument service agreements, also referred to as extended warranties. Revenue under these agreements is recognized ratably over the related service
period. Deferred revenue expected to be recognized during the 12 months following the balance sheet date is recorded as current portion of deferred revenue and the remaining portion is recorded as long-term.
Revenue Recognition
Products and Services Revenue
The Company generates revenue from sales of products, which consist of instruments and consumables, and services. Revenue from product sales is recognized when control of the product is transferred, which is generally upon shipment to the customer. Instrument service agreements, which relate to extended warranties, are typically entered into for a one-year term, following the expiration of the standard one-year warranty period. Revenue for extended warranties is recognized ratably over the term of the extended warranty period as a stand ready performance obligation. Revenue is recorded net of discounts, distributor commissions and sales taxes collected on behalf of governmental authorities. Customers are invoiced generally upon shipment, or upon order for services, and payment is typically due within 30 days. Cash received from customers in advance of product shipments or the provision of services is recorded as a contract liability. The Company’s contracts with its customers generally do not include rights of return or a significant financing component.
The Company regularly enters into contracts that include various combinations of products and services which are generally distinct and accounted for as separate performance obligations. The transaction price is allocated to each performance obligation in proportion to its standalone selling price. The Company determines standalone selling price using average selling prices with consideration of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, the Company relies upon prices set by management, adjusted for applicable discounts.
License and Royalty Revenue
The Company has agreements with third parties that include up-front fees and royalties. Revenue related to the delivery of intellectual property is recognized when the license is delivered to the third parties. Royalty revenue is recognized when the underlying sales occur. If the reporting of the actual sales from the Company’s licensees occurs after the Company’s reporting date, the Company estimates the royalty revenue receivable at the reporting date and adjusts for any changes in estimates in the following period.
Cost of Products and Services Revenue
Cost of product and services revenue primarily consists of manufacturing costs incurred in the production process, including personnel and related costs, component materials, labor and overhead, packaging and delivery costs and allocated costs including facilities and information technology. In addition, cost of product and services revenue includes royalty costs for licensed technologies included in the Company’s products, warranty costs and write-downs for slow-moving and obsolete inventory.
Shipping and Handling Costs
Shipping and handling charged to customers are recorded as revenue. Shipping and handling costs are included in the Company’s cost of revenue.
Research and Development
Research and development costs are expensed in the period incurred. Research and development expense consists of personnel and related costs, independent contractor costs, laboratory supplies, equipment maintenance, prototype and materials expenses, amortization of developed technology and intangibles and allocated costs including facilities and information technology.
Advertising Costs
Advertising costs are expensed as incurred. The Company incurred advertising costs of $2.5 million, $3.9 million and $3.3 million for the years ended December 31, 2025, 2024 and 2023, respectively.
Stock-Based Compensation
The Company’s stock-based compensation expense relates to stock options, restricted stock units (“RSUs”), performance stock units (“PSUs”), market-based performance stock awards ("PSAs") including performance stock options and performance RSUs granted pursuant to equity incentive plans, and stock purchase rights under an Employee Stock Purchase Plan (“ESPP”). Stock-based compensation expense for its stock-based awards is based on their grant date fair value. The Company determines the fair value of RSUs based on the closing price of its stock, which is listed on the Nasdaq Global Select Market, at the date of the
grant (or on the most recent trading day prior to grant, if the date of grant is not a trading day). The Company estimates the fair value of stock option awards under an equity incentive plan and stock purchase rights under an ESPP on the grant date using the Black-Scholes option-pricing model. The fair values of stock-based awards excluding PSUs and PSAs are recognized as compensation expense on a straight-line basis over the requisite service period in which the awards are expected to vest and forfeitures are recognized as they occur.
The Black-Scholes model considers several variables and assumptions in estimating the fair value of stock-based awards. These variables include the per share fair value of the underlying common stock, exercise price, expected term, risk-free interest rate, expected annual dividend yield and the expected stock price volatility over the expected term. The Company calculated the expected term using the simplified method, which is the mid-point between the vesting and contractual term. Due to the short trading period of the Company's stock, the Company has estimated volatility by reference to the historical volatilities of the Company and that of similar publicly traded peer companies. The risk-free interest rate is based on the yield available on U.S. Treasury zero-coupon issues similar in duration to the expected term of the equity-settled award.
For PSAs, the Company derives the valuation of the award and the requisite service period for each separately vesting portion of the award using a Monte Carlo simulation model and the related compensation expense is recognized over the derived service period using the accelerated attribution method commencing on the grant date. The derived service period is the median duration of the successful stock price paths to meet the respective escalating stock price thresholds as simulated in the Monte Carlo valuation model which uses assumptions such as volatility, risk-free interest rate, cost of equity and dividend estimated for the performance period of the PSAs. If the related market condition is achieved earlier than its estimated derived service period, the stock-based compensation expense will be accelerated, and a cumulative catch-up expense will be recorded during the period in which the market condition is met.
For PSUs, management reassesses the probability of vesting at each reporting period, and any changes in estimates are recognized on a cumulative catch-up basis for the stock-based compensation expense.
Foreign Currency
For foreign subsidiaries where the functional currency is the local currency, assets and liabilities are translated to the U.S. dollar using month-end exchange rates, and revenue and expenses using average exchange rates. The adjustments resulting from these foreign currency translations are recorded in “Accumulated other comprehensive income (loss).”
For entities where the functional currency is the U.S. dollar, monetary assets and liabilities are remeasured using exchange rates in effect at the balance sheet dates and non-monetary assets and liabilities are remeasured at historical exchange rates. Revenue and expenses are remeasured at the average exchange rates for the period. Gains or losses from foreign currency remeasurement are included in “Other income (expense), net” in the consolidated statements of operations.
Income Taxes
The Company uses the asset and liability method of accounting for income taxes, in which deferred tax assets and liabilities are recognized for the future tax consequences attributable to the differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets and liabilities are measured using the enacted tax rates expected to apply in the years in which those tax assets and liabilities are expected to be realized. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the period that includes the enactment date. A valuation allowance is established if it is more likely than not that all or a portion of the deferred tax asset will not be realized.
The Company’s tax positions are subject to income tax audits. The Company recognizes the tax benefit of an uncertain tax position only if it is more likely than not that the position is sustainable upon examination by the taxing authority, based on the technical merits. The tax benefit recognized is measured as the largest amount of benefit which is more likely than not (greater than 50% likely) to be realized upon settlement with the taxing authority. The Company recognizes interest accrued and penalties related to unrecognized tax benefits in its tax provision.
The Company calculates the current and deferred income tax provision based on estimates and assumptions that could differ from the actual results reflected in income tax returns filed in subsequent years. Adjustments based on filed income tax returns are recorded when identified. The amount of income tax paid is subject to examination by U.S. and foreign tax authorities. The estimate of the potential outcome of any uncertain tax issue is subject to management’s assessment of the relevant risks, facts and circumstances existing at that time. To the extent the assessment of such tax position changes, the change in estimate is recorded in the period in which the determination is made.
Net Loss Per Share
Net loss per share is computed using the two-class method required for multiple classes of common stock and participating securities. The rights, including the liquidation and dividend rights and sharing of losses, of the Class A common stock and
Class B common stock are identical, other than voting rights. As the liquidation and dividend rights and sharing of losses are identical, the undistributed earnings are allocated on a proportionate basis and the resulting net loss per share will, therefore, be the same for both Class A and Class B common stock on an individual or combined basis.
Basic net loss per share is computed by dividing net loss by the weighted-average number of shares of common stock outstanding during the period, adjusted for outstanding shares that are subject to repurchase.
For the calculation of diluted net loss per share, basic net loss per share is adjusted by the effect of dilutive securities including awards under the Company’s equity compensation plans. Diluted net loss per share is computed by dividing net loss by the weighted-average number of dilutive shares of common stock outstanding. For periods in which the Company reports net losses, diluted net loss per share is the same as basic net loss per share because potentially dilutive shares of common stock are not assumed to have been issued if their effect is anti-dilutive.
Recently Issued Accounting Pronouncement and Disclosure Rules
In December 2023, the Financial Accounting Standards Board (“FASB”) issued Accounting Standard Update (“ASU”) No. 2023-09, Income Taxes (“ASU No. 2023-09”), which prescribes standardized categories and disaggregation of information in the reconciliation of provision for income taxes, requires disclosure of disaggregated income taxes paid, and modifies other income tax-related disclosure requirements. The updated standard is effective beginning with the Company’s fiscal year 2025 annual reporting period. The Company adopted ASU No. 2023-09 in its fourth quarter of 2025 using a prospective transition method and the additional disclosures required under the standard are included in the Company’s financial statement disclosures.
In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses ("ASU 2024-03"), and in January 2025 issued ASU 2025-01, Clarifying the Effective Date ("ASU 2025-01") to provide clarification as to the effective date. ASU 2024-03 requires disaggregated disclosure of income statement expenses. ASU 2024-03 does not change the expense captions currently presented on the income statement; rather it requires disaggregation of certain expense captions into specified categories in disclosures within the footnotes to the financial statements. ASU 2024-03, as amended by ASU 2025-01, is effective for annual reporting periods beginning after December 15, 2026, and interim reporting periods within fiscal years beginning after December 15, 2027. ASU 2024-03 can be applied on a prospective basis; however, retrospective application is permitted. Early adoption is permitted. As ASU 2024-03 only requires additional disclosure, it will not have a material impact on the Company's financial condition and results of operations.
v3.25.4
Restructuring
12 Months Ended
Dec. 31, 2025
Restructuring and Related Activities [Abstract]  
Restructuring Restructuring
During the year ended December 31, 2025, the Company implemented a reduction in force plan in order to decrease costs and maintain a streamlined organization to support the business. Restructuring charges of approximately $10.6 million associated with restructuring, comprised primarily of severance-related costs and the impairment loss associated with the Scale Bio ROU assets, were recorded during the year ended December 31, 2025.
Restructuring costs of $0.5 million, $4.1 million and $6.0 million were recorded in cost of revenue, research and development expense, and selling, general and administrative expense, respectively, in the Company's consolidated statements of operations during the year ended December 31, 2025. No additional restructuring charges are expected to be incurred, and the restructuring activities are expected to be substantially completed by the end of the first quarter of 2026.
In 2023, the Company implemented a restructuring plan related to the closure of one of its research and development facilities resulting in restructuring charges of $2.5 million, comprised primarily of long-lived assets impairment costs and one-time employee termination benefits which were recorded during the year ended December 31, 2023. Restructuring costs of $2.5 million were recorded in research and development and general and administrative expenses during the year ended December 31, 2023 in the Company's consolidated statements of operations. The restructuring activities were completed as of December 31, 2024.
The following table is a summary of restructuring costs related to the Company’s restructuring activities for the years ended December 31, 2025, 2024 and 2023 (in thousands):
Termination Benefits CostsStock-Based Compensation
Expense
Long-lived Assets Impairment Expenses
Total
Balance at January 1, 2023$215 $— $— $215 
Restructuring charge310 — 2,171 2,481 
Cash payments made(215)— — (215)
Non-cash charge— — (2,171)(2,171)
Balance at December 31, 2023310 — — 310 
Restructuring charge259 — — 259 
Cash payments made(569)— — (569)
Balance at December 31, 2024— — — — 
Restructuring charge9,023 314 1,253 10,590 
Cash payments made(7,736)— — (7,736)
Non-cash charge— (314)(1,253)(1,567)
Balance at December 31, 2025$1,287 $— $— $1,287 
v3.25.4
Acquisitions
12 Months Ended
Dec. 31, 2025
Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract]  
Acquisitions Acquisitions
2025 Acquisition
On August 7, 2025, the Company entered into an agreement to acquire all outstanding shares of common stock of Scale Bio, a single cell genomics technology company. Upon closing the transaction on August 11, 2025, the Company made an upfront payment consisting of $9.2 million in cash and $13.5 million (1,099,992 shares) in shares of the Company’s Class A common stock. In the first quarter of 2026, the Company expects to pay $20.0 million, subject to any adjustments, in cash and in shares of the Company’s Class A common stock in connection with the technology transfer completed in the third quarter of 2025. In the future the Company may pay up to $30.0 million of contingent consideration if certain milestones are met.
The transaction was accounted for as an asset acquisition because substantially all of the fair value of the assets acquired is concentrated in the developed technology. The Company determined that the contingent consideration was within the scope of ASC 480, Distinguishing Liabilities from Equity, because the contingent consideration is payable in cash or shares of the Company’s Class A common stock, at the Company’s election. The contingent consideration was recorded at fair value as of the acquisition date. Upon closing, the Company recognized $22.4 million for the fair value of the contingent consideration.
The following table summarizes the value of assets acquired and liabilities assumed (in thousands) as of the closing on August 11, 2025:
Cash$1,390 
Developed technology51,639 
Other assets and liabilities, net(6,467)
Net identifiable assets acquired$46,562 
Other assets and liabilities, net includes assumed liabilities for pre-acquisition services provided to Scale Bio by third parties which are also measured at fair value under ASC 480. The Company will remeasure the contingent consideration and assumed liabilities within the scope of ASC 480 as of each applicable reporting period. Upon remeasurement as of December 31, 2025, the Company recorded a $1.4 million change in the fair value within “Other income (expense), net” in the Company’s consolidated statement of operations. Measurement of the liabilities using a probability weighted discounted cash flow approach is classified as a Level 3 fair value measurement due to the use of significant unobservable inputs. The calculation relies upon the probability of achieving the milestones and approximate timing of payment based on the terms of the arrangement.
The following table discloses the summary of changes in the contingent consideration and assumed liabilities measured at fair value using Level 3 inputs (in thousands):
Year Ended December 31, 2025
Beginning of period$— 
Contingent consideration to sellers22,378 
Assumed liabilities to third parties815 
Change in fair value1,407 
Balance at end of period$24,600 
Following the integration of Scale Bio’s operations, the Company determined to vacate a leased facility and recognized restructuring charges consisting of an impairment loss on the related ROU asset and severance-related costs during the year ended December 31, 2025. See Note 3, Restructuring, and Note 7, Commitments and Contingencies, for further details.
2023 Acquisition
In 2023, the Company signed an agreement to acquire certain intangible and other assets from Centrillion Technologies, Inc. and Centrillion Technology Holdings Corp. for an upfront cash payment of $10.0 million relating to an intellectual property license. Upon the close of the transaction on July 14, 2023, the Company paid additional cash consideration of $10.0 million upon acquiring the assets. Under the agreement, the Company is obligated to pay for certain technology development milestones if they are met. As of December 31, 2025, the Company has paid $41.3 million relating to the completion of development milestones. Up to $15.0 million of cash consideration is due if an additional technology development milestone is met.
The transaction was accounted for as an asset acquisition. In connection with this acquisition and milestone payments, the Company acquired an in-process research and development intangible asset of $61.0 million during the year ended December 31, 2023 which did not have alternative future use and therefore was recognized as an expense and included as a component of “In-process research and development” in the condensed consolidated statements of operations. The Company also acquired an intangible asset of $0.2 million related to assembled workforce which is included in “Intangible assets, net” in the consolidated balance sheets.
The following table summarizes the value of assets acquired and liabilities assumed as of the closing date (in thousands):
In-process research and development$60,980 
Intangible assets - acquired workforce200 
Property and equipment671 
Operating lease liabilities(1,496)
Other assets and liabilities, net758 
Total net assets acquired$61,113 
v3.25.4
Other Financial Statement Information
12 Months Ended
Dec. 31, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Other Financial Statement Information Other Financial Statement Information
Available-for-sale Securities
Available-for-sale securities at December 31, 2025 consisted of the following (in thousands):
December 31, 2025December 31, 2024
Amortized CostGross Unrealized GainsGross Unrealized LossesFair ValueAmortized CostGross Unrealized GainsGross Unrealized LossesFair ValueFair Value Measurement
Cash equivalents:
Money market funds$441,108 $— $— $441,108 $322,012 $— $— $322,012 Level 1
Marketable securities:
Government debt securities49,431 12 — 49,443 49,317 18 — 49,335 Level 2
Total available-for-sale securities$490,539 $12 $— $490,551 $371,329 $18 $— $371,347 
The contractual maturities of marketable securities as of December 31, 2025 were all less than one year.
The company incurred no gross realized losses from the sale of available-for-sales debt securities during the year ended December 31, 2025. During the years ended December 31, 2024 and 2023, the company incurred a de minimis gross realized loss and a gross realized loss of $1.7 million from the sale of available-for-sales debt securities, respectively. Realized gains (losses) on the sale of marketable securities are recorded in “Other expense, net” in the consolidated statements of operations.
The available-for-sale debt securities are subject to a periodic impairment review. For investments in an unrealized loss position, the Company determines whether a credit loss exists by considering information about the collectability of the instrument, current market conditions and reasonable and supportable forecasts of economic conditions. The Company recognizes an allowance for credit losses, up to the amount of the unrealized loss when appropriate, and writes down the amortized cost basis of the investment if it is more likely than not that the Company will be required or will intend to sell the investment before recovery of its amortized cost basis. Allowances for credit losses and write-downs are recognized in “Other expense, net,” and unrealized losses not related to credit losses are recognized in “Other comprehensive income (loss).” There are no allowances for credit losses for the periods presented.
Inventory
Inventory was comprised of the following (in thousands):
December 31,
20252024
Finished goods$23,183 $16,736 
Work in progress17,135 27,441 
Purchased materials16,023 38,930 
Inventory$56,341 $83,107 
Property and Equipment, Net
Property and equipment, net consisted of the following (in thousands):
December 31,
20252024
Building$147,493 $147,094 
Leasehold improvements89,724 89,567 
Laboratory equipment and machinery78,133 72,498 
Land36,765 36,765 
Computer equipment and software15,281 14,953 
Furniture and fixtures9,850 9,586 
Construction in progress2,929 5,152 
Total property and equipment380,175 375,615 
Less: accumulated depreciation and amortization(153,464)(122,967)
Property and equipment, net$226,711 $252,648 
Depreciation expense was $31.2 million, $33.9 million and $32.9 million for the years ended December 31, 2025, 2024, and 2023, respectively.
During the year ended December 31, 2025, the Company recorded impairment charges of $0.1 million related to leasehold improvements. During the year ended December 31, 2024, the Company recorded impairment charges of $2.1 million related to computer equipment and software of which $0.3 million, $0.7 million and $1.1 million was classified in cost of revenue, research and development, and selling, general and administrative expenses, respectively, in the consolidated statement of operations. The impairment charge was triggered by a decision to discontinue a productivity engineering project.
Intangible Assets, Net
Intangible assets, net consisted of the following (dollars in thousands):
December 31, 2025December 31, 2024
Remaining Useful Life in YearsGross
Carrying
Amount
Accumulated
Amortization
Intangibles,
Net
Gross
Carrying
Amount
Accumulated
Amortization
Intangibles,
Net
Developed technology6.0$52,639 $(3,359)$49,280 $1,000 $(92)$908 
Technology licenses8.822,504 (9,491)13,013 22,504 (8,016)14,488 
Assembled workforce0.51,328 (1,292)36 1,328 (1,080)248 
Customer relationships0.0945 (945)— 945 (918)27 
Intangible assets, net$77,416 $(15,087)$62,329 $25,777 $(10,106)$15,671 
During the year ended December 31, 2025, the Company recorded developed technology of $51.6 million and assembled workforce of $0.7 million in connection with the Scale Bio acquisition. The amortization of developed technology is recorded in cost of revenue. See Note 4, Acquisitions, for details related to intangibles acquired.
During the year ended December 31, 2025, the Company recorded an impairment loss of $0.7 million for the assembled workforce. During the year ended December 31, 2023, the Company recorded impairment charges of $4.6 million related to its developed technology and assembled workforce. No impairment losses were recognized for intangible assets during the year ended December 31, 2024.
The estimated annual amortization of intangible assets for the next five years is shown below (in thousands):
Estimated
Annual
Amortization
2026$9,644 
20279,609 
20289,609 
20299,608 
20309,569 
Thereafter14,290 
Total$62,329 
Amortization expense to be reported in future periods could differ from these estimates as a result of acquisitions, divestitures and asset impairments, among other factors.
Accrued Compensation and Related Benefits
Accrued compensation and related benefits were comprised of the following (in thousands):
December 31,
20252024
Accrued bonus$29,506 $21,859 
Accrued commissions5,335 5,938 
Accrued payroll and related costs4,964 2,970 
Other2,695 2,848 
Accrued compensation and related benefits$42,500 $33,615 
Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities were comprised of the following (in thousands):
December 31,
20252024
Taxes payable$7,219 $4,936 
Product warranties6,828 8,615 
Customer refunds and deposits payable5,542 3,002 
Accrued royalties for licensed technologies4,971 7,042 
Accrued professional services2,914 5,315 
Accrued legal and related costs1,502 6,100 
Accrued property and equipment124 644 
Other10,871 5,511 
Accrued expenses and other current liabilities$39,971 $41,165 
Product Warranties
Changes in the reserve for product warranties were as follows (in thousands):
Year Ended December 31,
20252024
Beginning of period$8,615 $8,116 
Amounts charged to cost of revenue8,567 13,325 
Repairs and replacements(10,354)(12,826)
End of period$6,828 $8,615 
Revenue and Deferred Revenue
As of December 31, 2025, the aggregate amount of remaining performance obligations primarily related to separately sold extended warranty service agreements, or allocated amounts for extended warranty service agreements bundled with sales of instruments, was $34.4 million, of which approximately $23.9 million is expected to be recognized to revenue in the next 12 months, with the remainder thereafter. The contract liabilities of $34.4 million and $33.2 million as of December 31, 2025 and 2024, respectively, primarily consisted of deferred revenue related to extended warranty service agreements.
Year Ended December 31,
20252024
Beginning of period$33,171 $21,964 
Revenue recognized that was included in the contract liability at the beginning of the year(20,130)(11,407)
Revenue deferred excluding amounts recognized as revenue during the period21,362 22,614 
End of period$34,403 $33,171 
The following table represents revenue by source for the periods indicated (in thousands). Spatial products include the Company’s Visium and Xenium products:
Year Ended December 31,
202520242023
Instruments
Single Cell$22,671 $35,212 $47,866 
Spatial34,108 57,503 75,605 
Total instruments revenue56,779 92,715 123,471 
Consumables
Single Cell363,206 372,308 420,316 
Spatial143,977 121,124 59,237 
Total consumables revenue507,183 493,432 479,553 
Services32,726 24,317 15,703 
Products and services revenue596,688 610,464 618,727 
License and royalty revenue46,135 321 — 
Total revenue$642,823 $610,785 $618,727 
The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):
Year Ended December 31,
202520242023
Americas
United States (a)
$346,512 $334,318 $360,091 
Americas (excluding United States)12,261 13,447 13,101 
Total Americas358,773 347,765 373,192 
Europe, Middle East and Africa161,716 159,762 142,276 
Asia-Pacific
China70,264 57,300 50,965 
Asia-Pacific (excluding China)52,070 45,958 52,294 
Total Asia-Pacific122,334 103,258 103,259 
Total revenue$642,823 $610,785 $618,727 
__________________________
(a) Includes license and royalty revenue.
License and Royalty Revenue
In February 2025, the Company settled its worldwide patent litigation with Vizgen, Inc. (“Vizgen”). As part of that settlement, Vizgen has limited rights to certain intellectual property owned or exclusively licensed by the Company. As one part of the settlement, the Company received an upfront payment of $26.0 million and receives royalties on Vizgen’s sales of products covered by the license. The $26.0 million upfront payment was recorded as a $9.2 million gain on settlement and $16.8 million in license and royalty revenue. The amount attributed to the gain on settlement was determined by applying a royalty rate to Vizgen’s historical revenues prior to the settlement.
In May 2025, the Company entered into a settlement agreement and license agreements with Bruker Corporation (“Bruker”) resolving all outstanding litigation and other proceedings between the parties across all jurisdictions around the world. Under the agreements, the Company has the right to receive four quarterly installment payments beginning in the third quarter of 2025, which total $68.0 million, and applicable interest. The Company receives royalties on Bruker’s sales of products and services covered by the license. The $68.0 million amount was recorded as a $40.7 million gain on settlement and $27.3 million in license and royalty revenue. The amount attributed to the gain on settlement was determined by applying a royalty rate to the historical revenues prior to the settlement. As of December 31, 2025, the Company had received two quarterly installment payments from Bruker, and the remaining balance was recognized under other receivables which is presented separately on the Company’s consolidated balance sheets.
Other Income (Expense), Net
“Other income (expense), net” in the consolidated statements of operations primarily consists of gains or losses from foreign currency remeasurement and fair value adjustments of contingent consideration. The Company recognized a foreign currency transaction gain of $2.5 million for the year ended December 31, 2025, a foreign currency transaction loss of $2.1 million for the year ended December 31, 2024, and a foreign currency transaction gain of $1.2 million for the year ended December 31, 2023. The Company recognized a $1.4 million change in fair value of contingent consideration related to the Scale Bio acquisition for the year ended December 31, 2025.
v3.25.4
Income Tax
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Income Tax Income Tax
Income (loss) before provision for income taxes were as follows (in thousands):
Year Ended December 31,
202520242023
United States$(44,598)$(187,720)$(263,292)
International4,691 10,020 14,529 
Total$(39,907)$(177,700)$(248,763)
The provision for income taxes consisted of the following (in thousands):
Year Ended December 31,
202520242023
Current provision:
Federal$(7)$396 $351 
State397 314 180 
Foreign3,557 3,508 6,252 
Total current provision for income taxes3,947 4,218 6,783 
Deferred provision:
Federal— — — 
State— — — 
Foreign(310)709 (447)
Total deferred provision for income taxes(310)709 (447)
Provision for income taxes$3,637 $4,927 $6,336 
A reconciliation of the federal statutory income tax provision to the effective income tax provision is as follows (in thousands):
Year Ended December 31, 2025
AmountPercent
U.S. federal statutory tax rate$(8,380)21 %
State and local income taxes, net of federal income tax effect (a)
(2,363)%
Foreign tax effects
Singapore
Nondeductible compensation1,179 (3)%
Other(248)%
Other foreign jurisdictions274 (1)%
Effect of cross-border tax laws336 (1)%
Tax credits
   Research and development tax credits(4,250)11 %
Changes in valuation allowance(5,038)13 %
Nontaxable or nondeductible items
   Stock-based compensation14,551 (37)%
Executive compensation (162(m))1,208 (3)%
   Other items503 (1)%
Changes in unrecognized tax benefits5,865 (15)%
Effective tax rate$3,637 (9)%
___________________
(a) State taxes in California, Pennsylvania and Texas made up the majority (greater than 50 percent) of the tax effect in this category.

Year Ended December 31,
20242023
Income tax provision at federal statutory rate$(37,317)$(52,240)
State taxes, net of federal benefit(11,938)(14,831)
Tax credits(8,895)(14,551)
Foreign taxes2,148 3,888 
Stock-based compensation15,978 2,422 
Change in valuation allowance36,378 79,551 
Acquisition related expenses— 2,296 
Waived deductions under Section 59A8,190 — 
Other383 (199)
Total provision for income taxes$4,927 $6,336 
Deferred income taxes reflect the net tax effect of temporary differences between amounts recorded for financial reporting purposes and amounts used for tax purposes. The major components of deferred tax assets and liabilities are as follows (in thousands):
Year Ended December 31,
20252024
Deferred tax assets
Net operating loss carryforwards$202,704 $161,681 
Research and development tax credits111,143 103,555 
Accruals and reserves17,323 12,302 
Operating lease liability19,441 19,628 
Intangibles27,845 35,966 
Stock-based compensation24,383 26,772 
Capitalized research and development
103,001 136,267 
Total deferred tax assets505,840 496,171 
Valuation allowance(490,154)(479,452)
Net deferred tax assets15,686 16,719 
Deferred tax liabilities
Property and equipment(2,855)(4,124)
Operating right-of-use assets(13,436)(13,510)
Total deferred tax liabilities(16,291)(17,634)
Net deferred tax liabilities$(605)$(915)
As of December 31, 2025 and 2024, the Company maintained a full valuation allowance on its U.S. net deferred tax assets. The U.S. deferred tax assets predominantly relate to operating losses, tax credits and capitalized research and development intangibles. The U.S. valuation allowance was estimated based on an assessment of both positive and negative evidence to determine whether it is more likely than not that deferred tax assets are recoverable. Such assessment is required on a jurisdiction-by-jurisdiction basis. The Company’s history of cumulative losses, along with expected future U.S. losses, required that a full valuation allowance be recorded against all U.S. net deferred tax assets. The Company intends to maintain a full valuation allowance on U.S. net deferred tax assets until sufficient positive evidence exists to support a reversal of the valuation allowance. The valuation allowance increased by $10.7 million and by $36.4 million for the years ended December 31, 2025 and 2024, respectively.
As of December 31, 2025, the Company had federal net operating loss (“NOL”) carryforwards of $808.1 million and federal tax credit carryforwards of $93.8 million. The federal NOL carryforwards generated after December 31, 2017 totaling $802.3 million are carried forward indefinitely, while all other federal NOL and tax credit carryforwards expire beginning in 2033 and 2036, respectively. As of December 31, 2025, the Company had state NOL carryforwards of $506.5 million, which begin to expire primarily in 2033. In addition, the Company had state tax credit carryforwards of $77.4 million, which do not expire.
Utilization of the net operating loss and tax credit carryforwards may be subject to an annual limitation due to the ownership change limitations provided by the Internal Revenue Code of 1986, as amended, and similar state provisions. Any annual limitation may result in the expiration of net operating losses and credits before utilization. If an ownership change occurred, utilization of the net operating loss and tax credit carryforwards could be significantly reduced.
Income taxes paid, net of refunds received, consisted of the following (in thousands):
Year Ended December 31, 2025
AmountPercent
State$195 %
Foreign
Singapore947 40 %
Other foreign jurisdictions1,249 52 %
Total income taxes paid, net of refunds received$2,391 100 %
The total balance of unrecognized gross tax benefits, resulting primarily from research and development tax credits claimed on the Company’s annual tax returns, were as follows (in thousands):
20252024
Unrecognized tax benefits at beginning of year$50,022 $45,713 
Reductions related to settlements with tax authorities— (285)
Reductions based on prior year tax provisions(739)(1,617)
Additions related to acquisitions2,287 — 
Additions based on prior year tax provisions436 467 
Additions based on current year tax provisions3,484 5,744 
Unrecognized tax benefits at end of year$55,490 $50,022 
The total amount of unrecognized gross tax benefits was $55.5 million and $50.0 million as of December 31, 2025 and 2024, respectively, of which $3.3 million and $2.9 million, if recognized, would affect our effective tax rate, respectively.
The Company is subject to the examination of its income tax returns by the U.S. Internal Revenue Service and other domestic and foreign tax authorities. The United States, California, Singapore, and Sweden are considered as major jurisdictions. The Company has not been audited in such jurisdictions. Tax examinations are expected to focus primarily on research and development tax credits and intercompany transfer pricing practices. Due to NOLs and tax credit carryforwards, as of December 31, 2025, federal and California income tax returns for the years ended 2012 through the current period are open to examination. Significant foreign income tax returns for the years 2019 through the current period are open to examination. Due to the number of years remaining that are subject to examination, the Company is unable to estimate the full range of possible adjustments to the balance of gross unrecognized tax benefits.
The Company includes interest and penalties related to income tax matters within the provision for income taxes. The total amount of gross interest and penalties accrued was $2.1 million and $1.6 million for the years ended December 31, 2025 and 2024, respectively. The Company recognized interest and penalty expenses of $0.6 million, $0.7 million and $0.5 million for the years ended December 31, 2025, 2024 and 2023, respectively.
The Company maintained undistributed earnings overseas as of December 31, 2025, and the Company believed the funds held by all non-U.S. subsidiaries will be permanently reinvested outside of the U.S. However, if these funds were repatriated to the U.S. or used for U.S. operations, the Company may be subject to withholding taxes in the foreign countries. As a result of tax reform, the Company’s unrepatriated earnings are no longer subject to federal income tax in the U.S. when distributed.
v3.25.4
Commitments and Contingencies
12 Months Ended
Dec. 31, 2025
Commitments and Contingencies Disclosure [Abstract]  
Commitments and Contingencies Commitments and Contingencies
Indemnification
From time to time, the Company has entered into indemnification provisions under certain agreements in the ordinary course of business, typically with business partners, customers and suppliers. Pursuant to these agreements, the Company may indemnify, hold harmless and agree to reimburse the indemnified parties on a case-by-case basis for losses suffered or incurred by the indemnified parties in connection with any patent or other intellectual property infringement claim by any third party with respect to the Company’s products. The Company maintains product liability insurance coverage that would generally enable it to recover a portion of the amounts paid. The Company has also agreed to indemnify its directors and executive officers for costs associated with any fees, expenses, judgments, fines and settlement amounts incurred by them in any action or proceeding to which any of them are, or are threatened to be, made a party by reason of their service as a director or officer (see “—Litigation” below). The Company also may be subject to indemnification obligations by law with respect to the actions of its employees under certain circumstances and in certain jurisdictions.
Non-cancelable Purchase Commitments
The Company’s contract manufacturers make advance purchases of components based on the instrument unit forecasts and purchase orders placed by the Company. To the extent these components are purchased by a contract manufacturer on the Company’s behalf and cannot be used by their other customers, the Company is obligated to purchase these components. In addition, certain supplier agreements require the Company to make minimum annual purchases under the agreements. As of December 31, 2025, the Company had commitments to make a total of $12.2 million in purchases over the next two years.
As of December 31, 2025, the Company had entered into non-cancelable arrangements for subscription software services to make payments aggregating to $18.6 million over the next four years.
Intellectual Property Licensing
The minimum commitments related to the Company's license arrangements aggregate to $24.9 million as of December 31, 2025 to be paid over the next 16 years.
Lease Agreements
The Company leases office, laboratory, manufacturing, distribution and server space with lease terms up to 10 years. These leases require monthly lease payments that may be subject to annual increases throughout the lease term. Certain of these leases also include renewal options at the election of the Company to renew or extend the lease. The Company evaluates renewal options at lease inception and on an ongoing basis and includes renewal options that it is reasonably certain to exercise in its expected lease terms when classifying leases and measuring lease liabilities.
In August 2025, the Company recorded $1.8 million in right of use asset and lease liabilities in connection with Scale Bio acquisition. See Note 3, Asset Acquisition, for details related to right of use assets and lease liabilities acquired. As of December 31, 2025, the Company recognized an impairment loss of approximately $1.3 million related to the ROU assets associated with the Scale Bio leased facility as a result of the decision to vacate the facility to optimize asset utilization and improve operational efficiency following the integration of existing operations.
For the years ended December 31, 2025, 2024 and 2023, the Company incurred $12.5 million, $12.6 million and $13.6 million, respectively, of operating lease costs and $1.0 million, $0.5 million and $0.2 million, respectively, of variable lease costs. The variable lease cost is comprised primarily of the Company’s proportionate share of operating expenses, property taxes and insurance and is classified as lease cost due to the Company’s election to not separate lease and non-lease components. The sublease income for the years ended December 31, 2025, 2024 and 2023, were $0.6 million, $1.2 million and $0.5 million, respectively.
Cash paid for amounts included in the measurement of operating lease liabilities for the years ended December 31, 2025, 2024 and 2023 were $16.2 million, $17.8 million and $15.2 million, respectively, and were included in net cash used in operating activities in the Company’s consolidated statements of cash flows.
The payments due under of the Company’s operating lease liabilities as of December 31, 2025 are as follows (in thousands):
Operating Leases
2026$15,630 
202716,805 
202816,394 
202914,800 
20309,853 
Thereafter29,537 
Total lease payments$103,019 
Less: imputed interest(18,658)
Present value of operating lease liabilities$84,361 
Operating lease liabilities, current$10,985 
Operating lease liabilities, noncurrent73,376 
Total operating lease liabilities$84,361 
The following table summarizes additional information related to the Company’s operating leases:
December 31, 2025December 31, 2024
Weighted-average remaining lease term:
Operating leases6.7 years6.8 years
Weighted-average discount rate:
Operating leases5.9 %5.8 %
Litigation
The Company is regularly subject to lawsuits, claims, arbitration proceedings, administrative actions and other legal and regulatory proceedings involving intellectual property disputes, commercial disputes, competition and other matters, and the Company may become subject to additional types of lawsuits, claims, arbitration proceedings, administrative actions, government investigations and legal and regulatory proceedings in the future. As of December 31, 2025, the Company has concluded that a loss is not probable and a contingent liability has not been recorded.
Parse
In August 2022, the Company filed suit against Parse Biosciences, Inc. (“Parse”) in the U.S. District Court for the District of Delaware alleging that Parse’s Evercode Whole Transcriptomics products and ATAC-seq products infringe U.S. Patent Nos. 10,155,981 (the “981 patent”), 10,697,013 (the “013 patent”), 10,240,197 (the “197 patent”), 10,150,995 (the “995 patent”), 10,619,207 (the “207 patent”) and 10,738,357 (the “357 patent”). In February 2025, the Court entered a consent judgment and permanent injunction against Parse with respect to the 995, 207 and 357 patents relating to ATAC-seq. Parse filed petitions for Inter Partes Review (“IPR”) of the 981, 197 and 013 patents which were found unpatentable by the Patent Trial and Appeals Board in February 2025. The Company strongly disagrees with those decisions and has appealed. The Court has stayed the litigation pending the outcome of the appeals.
In August 2025, the Company acquired Scale Bio. Scale Bio and Parse are parties in a litigation in the U.S. District Court for the District of Delaware in which Scale Bio is asserting that Parse’s Evercode products infringe U.S. Patent Nos. 10,626,442, 10,982,256, 11,512,341 and 11,634,752 (the “752 patent”) and Parse is asserting the Scale Bio’s single cell sequencing products infringe U.S. Patent Nos. 10,900,065, 11,168,355 and 11,427,856 (the “Asserted Parse Patents”). On February 13, 2025 the parties filed a stipulation agreeing that Scale Bio’s High Throughput Assay and methods of using such assays do not infringe the Asserted Parse Patents, and dismissing such claims. In October 2025, the Court entered summary judgment that the 752 patent is invalid. The Company disagrees with this decision and plans to appeal. In November 2025, the Court entered summary judgment that the accused Scale Bio products do not infringe the Asserted Parse Patents. Additional summary judgment motions are pending and a trial date has not been set.
Curio
In December 2023, the Company filed suit against Curio Bioscience, Inc. (“Curio”) in the U.S. District Court for the District of Delaware alleging that the Curio Seeker Spatial Mapping Kit and associated products and services infringe U.S. Patent Nos. 10,480,022, 10,662,468, 11,001,879, 11,549,138 and 11,761,030. Trial is scheduled for May 2026.
In December 2023, the Company filed a request for a preliminary injunction in the Dusseldorf Local Division of the UPC alleging that the Curio Seeker Spatial Mapping Kit and associated products and services infringe EP Patent No. 2697391 (the “EP 391 patent”). In April 2024, the UPC granted the Company’s request and issued a preliminary injunction requiring Curio to stop offering, marketing, using or possessing these Curio Seeker products and services in Germany, France and Sweden. Curio did not appeal the preliminary injunction. On March 25, 2024, the Company filed a main request in the Dusseldorf Local Division of the UPC alleging that the Curio Seeker Spatial Mapping Kit and associated products and services infringe the EP 391 patent. In June 2025, the UPC found that Curio infringes one of the patent’s claims and issued a permanent injunction ordering Curio to cease and desist from selling the Seeker products in Germany, France and Sweden.
Illumina
In October 2025, the Company filed two lawsuits against Illumina, Inc. (“Illumina”) in the United States District Court for the District of Delaware. In the first suit, the Company alleges Illumina’s announced spatial technology program infringe U.S. Patent Nos. 11,008,607, 11.549,138, 12,234,505 and 12,297,487. In the second suit, the Company alleges Illumina’s single cell kits and workflow infringe U.S. Patent Nos. 11,692,214, 11,932,902, 12,275,993, 12,305,239 and 12,416,192. Illumina filed its answers in December 2025 and an amended answer in the single cell suit in February 2026. No case schedule has been set.
v3.25.4
Capital Stock
12 Months Ended
Dec. 31, 2025
Equity [Abstract]  
Capital Stock Capital Stock
The Company’s Amended and Restated Certificate of Incorporation authorizes it to issue 1,200,000,000 shares of capital stock consisting of 1,000,000,000 shares of Class A common stock, 100,000,000 shares of Class B common stock, and 100,000,000 shares of preferred stock.
Common Stock
The following table represents the number of shares of Class B common stock converted to shares of Class A common stock upon the election of the holders of such shares during the years:
Year Ended December 31,
202520242023
Class B common stock converted to Class A common stock3,977,961 — 4,610,422 
The Company’s Class A common stock and Class B common stock have a par value of $0.00001 per share. Each share of Class B common stock has the right to ten votes and each share of Class A common stock has the right to one vote per share. All other rights and privileges of Class A and Class B common stock are equivalent. Class B common shares are convertible to Class A common shares at any time upon written notification and all Class B common shares will convert upon the date specified by vote or written consent of the holders of a majority of the then outstanding Class B common stock, voting together as a single class. The holders of common stock are also entitled to receive dividends whenever funds are legally available and when declared by the Board of Directors, subject to the prior rights of holders of all classes of stock outstanding having priority rights as to dividends.
v3.25.4
Equity Incentive Plans
12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Equity Incentive Plans Equity Incentive Plans
Amended and Restated 2012 Stock Plan
Following the adoption of the 2019 Omnibus Incentive Plan in September 2019, any awards outstanding under the Amended and Restated 2012 Stock Plan (“2012 Plan”) continue to be governed by their existing terms but no further awards may be granted under the 2012 Plan. As of December 31, 2025, the number of shares of Class A common stock issuable under the 2012 Plan, which includes shares issuable upon the exercise of outstanding awards, was 1,295,245.
2019 Omnibus Incentive Plan
The 2019 Omnibus Incentive Plan (“2019 Plan”) allows for the issuance of incentive stock options, non-statutory stock options (“NSOs”) or restricted shares. Incentive stock options may be granted only to the Company’s employees (including officers and directors who are also considered employees). NSOs and restricted shares may be granted to the Company’s employees and service providers. As of December 31, 2025, the number of shares of Class A common stock available for issuance under the 2019 Plan was 10,092,793 shares issuable in connection with outstanding awards and 21,857,245 shares reserved for issuance in connection with grants of future awards.
The number of shares of Class A common stock reserved for issuance under the 2019 Plan at the time the 2019 Plan was adopted in 2019 was 11,000,000. The 2019 Plan provides that the total number of shares of the Company’s Class A common stock that may be issued under the 2019 Plan, including options authorized and options outstanding, is 11,000,000 (such share limit as increased from time to time, the “Absolute Share Limit”). However, the Absolute Share Limit shall be increased on the first day of each calendar year commencing on January 1, 2021 and ending on January 1, 2029 in an amount equal to the lesser of (i) 5% of the total number of shares of common stock outstanding on the last day of the immediately preceding fiscal year and (ii) such number of shares of the Company’s Class A common stock as determined by the Company’s board of directors. However, if on January 1 of a calendar year, the Company’s board of directors has not either confirmed the 5% increase described in clause (i) or approved a lesser number of shares of the Company’s Class A common stock for such calendar year, then the Company’s board of directors will be deemed to have waived the automatic increase, and no such increase will occur for such calendar year. Of the Absolute Share Limit, no more than 11,000,000 shares of Class A common stock may be issued in the aggregate pursuant to the exercise of incentive stock options granted under the 2019 Plan.
Options issued under the 2019 Plan have a contractual term of 10 years. The exercise price of an incentive stock option and NSO shall not be less than 100% of the fair market value of the shares on the date of grant.
Stock Options
A summary of the Company’s stock option activity under the 2012 and 2019 Plans is as follows:
Outstanding
Options
Weighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Term
(Years)
Aggregate
Intrinsic Value
Balance as of December 31, 20244,594,582 $45.37 5.4$13,834,082 
Exercised(478,085)2.83 
Forfeited(555,200)61.62 
Balance as of December 31, 20253,561,297 $48.55 4.6$10,337,526 
Vested and exercisable as of December 31, 20253,253,508 $49.02 4.4$10,337,526 
The Company did not grant stock options during the years ended December 31, 2025 and 2024. The weighted-average grant date fair value of options granted during the year ended December 31, 2023 was $33.67 per share. The total intrinsic value of stock options exercised was $4.4 million, $12.3 million and $78.0 million during the years ended December 31, 2025, 2024, and 2023, respectively. As of December 31, 2025, the total unrecognized stock-based compensation related to stock options was $4.9 million, which will be recognized over a weighted-average period of approximately one year.
The fair value of each employee option granted in 2023 was estimated on the date of grant using the Black-Scholes option pricing model and the following assumptions for the periods indicated:
Year Ended December 31, 2023
Expected volatility
70% – 71%
Risk-free interest rate
3.7% – 4.6%
Expected term
5.3 – 6.1 years
Expected dividend—%
Restricted Stock Units
Restricted stock units (“RSUs”) activity for the year ended December 31, 2025 is as follows:
Restricted Stock
Units
Weighted-Average
Grant Date Fair Value
(per share)
Balance as of December 31, 20246,493,387 $35.55 
Granted6,184,585 10.65 
Vested(3,117,074)30.68 
Forfeited(1,734,157)27.12 
Outstanding as of December 31, 20257,826,741 $19.68 
As of December 31, 2025, the total unrecognized stock-based compensation related to RSUs was $118.0 million, which will be recognized over a weighted-average period of approximately two years.
Performance Stock Awards
In March 2025, the Company granted 561,603 PSUs (“2025 PSUs”) under the 2019 Plan to certain members of management which are subject to the achievement of certain performance conditions established by the Company’s Compensation Committee of the Board of Directors as described below:
i.50% of target 2025 PSUs earned will be based on the Company’s compound annual growth rate (“CAGR”) of the Company’s revenue over a two-year performance period from January 1, 2025 to December 31, 2026. Holders may earn from 0% to 200% of the target amount of shares and earned 2025 PSUs will then be subject to service-based vesting; and
ii.50% of target 2025 PSUs earned will be based on the relative Total Shareholder Return (“TSR”) of the Company’s Class A common stock as compared to the TSR of the members of the Russell 3000 Medical Equipment and Services Sector Index over a three-year performance period from January 1, 2025 to December 31, 2027. Depending on the results relative to the TSR market condition, the holders may earn from 0% to 200% of the target amount of shares which will vest at the end of the performance period.
The 2025 PSUs will be forfeited if the performance or market conditions are not achieved at the end of the relative performance periods as described above. The vesting of the 2025 PSUs can also be triggered upon certain change in control events or in the event of death or disability.
The weighted-average grant date fair values of the 2025 PSUs relating to CAGR and TSR components were $10.76 and $13.94 per share, respectively. Stock-based compensation expense recognized for the 2025 PSUs relating to TSR components was $1.0 million for the year ended December 31, 2025. The vesting of the CAGR components of the 2025 PSUs was deemed not probable of vesting as of December 31, 2025, which resulted in no stock-based compensation expense recognized for the year ended December 31, 2025.
The Company estimated the fair values of the shares granted under the TSR component of the 2025 PSUs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2025
Expected volatility 67%
Risk-free interest rate4.0%
Expected dividend yield—%
In March 2024, the Company granted 219,168 PSUs (“2024 PSUs”) under the 2019 Plan to certain members of management which are subject to the achievement of certain performance conditions established by the Company’s Compensation Committee of the Board of Directors as described below:

i.50% of target 2024 PSUs earned were based on the Company’s CAGR of the Company’s revenue over a two-year performance period from January 1, 2024 to December 31, 2025. Holders could have earned from 0% to 175% of the target amount of shares and earned 2024 PSUs would have then been subject to service-based vesting; and

ii.50% of target 2024 PSUs earned will be based on the relative TSR of the Company’s common stock as compared to the TSR of the members of the Russell 3000 Medical Equipment and Services Sector Index over a three-year performance period from January 1, 2024 to December 31, 2026. Depending on the results relative to the TSR market condition, the holders may earn from 0% to 200% of the target amount of shares which will vest at the end of the performance period.
The 2024 PSUs were or will be forfeited if the performance or market conditions were or are not achieved at the end of the relative performance periods as described above. The Company did not achieve the revenue CAGR performance condition over the two-year performance period; accordingly, the PSUs subject to this performance condition were forfeited as of December 31, 2025. The vesting of the 2024 PSUs subject to the relative TSR condition can also be triggered upon certain change in control events or in the event of death or disability.
The weighted-average grant date fair values of the 2024 PSUs relating to CAGR and TSR components were $37.43 and $44.80 per share respectively. Stock-based compensation expense recognized for the 2024 PSUs relating to TSR components was $1.3 million for each of the years ended December 31, 2025 and 2024. The vesting of the CAGR component for the 2024 PSUs was deemed not probable of vesting as of December 31, 2025 and December 31, 2024, which resulted in no stock-based compensation expense recognized for the years ended December 31, 2025 and 2024.
The Company estimated the fair values of the shares granted under the TSR component of the 2024 PSUs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2024
Expected volatility 66%
Risk-free interest rate4.5%
Expected dividend yield—%
In March 2023, the Company granted 172,842 PSAs (“2023 PSAs”) under the 2019 Plan to certain members of management, which are subject to the achievement of certain escalating stock price thresholds established by the Company's Compensation Committee of the Board of Directors.
The 2023 PSAs each vest in equal installments upon the achievement of escalating stock price thresholds of $72.14, $96.19 and $120.24, respectively, calculated based on the volume-weighted average price per share of the Company’s Class A common stock over the immediately trailing 20 trading day period for each respective threshold. The escalating stock price thresholds can be met any time prior to the fifth anniversary of the date of grant. The vesting of the 2023 PSAs can also be triggered upon certain change in control events and achievement of certain change in control price thresholds, or in the event of death or disability. The weighted-average grant date fair value of the 2023 PSAs was $43.13. Stock-based compensation expense recognized for the 2023 PSAs was $1.7 million and $5.1 million for the years ended December 31, 2024 and 2023, respectively.
The Company estimated the fair values of shares granted under the 2023 PSAs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2023
Expected volatility71%
Risk-free interest rate3.7%
Expected dividend—%
In September 2022, the Company granted 709,025 PSAs (“2022 PSAs”) including RSUs and a performance stock option under the 2019 Plan to certain members of management, which are subject to the achievement of certain stock price thresholds established by the Company’s Compensation Committee of the Board of Directors.
Stock-based compensation expense recognized for the 2022 PSAs was $2.4 million and $10.0 million for the years ended December 31, 2024 and 2023, respectively.
2019 Employee Stock Purchase Plan
In July 2019, the Company’s board of directors adopted the 10x Genomics, Inc. 2019 Employee Stock Purchase Plan (the “ESPP”), which was subsequently approved by the Company’s stockholders. The ESPP went into effect on September 11, 2019. Subject to any limitations contained therein, the ESPP allows eligible employees to contribute, through payroll deductions, up to 15% of their eligible compensation to purchase the Company’s Class A common stock at a discounted price per share. The ESPP generally provides for consecutive 6-month offering periods.
During the years ended December 31, 2025, 2024 and 2023, 708,628, 385,967, and 217,537 shares of Class A common stock, respectively, were issued under the ESPP. The ESPP provides that the maximum number of shares of the Company’s Class A common stock made available for sale thereunder will be 4,909,589, which number will be automatically increased on the first day of each calendar year commencing on January 1, 2021 and ending on January 1, 2029 in an amount equal to the lesser of (i) 1% of the total number of shares of common stock outstanding on the last day of the immediately preceding fiscal year and (ii) such number of shares of the Company’s Class A common stock as determined by the Company’s board of directors. However, if on January 1 of a calendar year the Company’s board of directors has not either confirmed the 1% described in clause (i) or approved a lesser number of shares of the Company’s Class A common stock for such calendar year, the Company’s board of directors will be deemed to have waived the automatic increase and no such increase will occur for such calendar year. The maximum number of shares available under the ESPP (and any share limitations thereunder, as applicable) will automatically be adjusted upon certain changes to the Company’s capital structure. As of December 31, 2025, there were 3,223,673 shares available for issuance under the ESPP.
For the years ended December 31, 2025, 2024, and 2023 the weighted average grant date fair values of options granted under the ESPP, using the Black-Scholes option pricing model, were $4.07, $6.42, and $16.91 respectively.
The following assumptions were used in estimating the fair values of shares under the ESPP:
Year Ended December 31,
202520242023
Expected volatility
67% – 75%
49% – 80%
49% – 58%
Risk-free interest rate
3.80% – 4.30%
4.44% – 5.4%
5.24% – 5.41%
Expected term (in years)
0.5
0.5
0.5
Expected dividend—%—%—%
As of December 31, 2025, the total unrecognized stock-based compensation related to the ESPP was $1.0 million, which will be recognized over a weighted-average period of approximately 0.4 years.
Stock-based Compensation
The Company recorded stock-based compensation expense in the consolidated statement of operations for the periods presented as follows (in thousands):
Year Ended December 31,
202520242023
Cost of revenue$8,497 $8,348 $7,068 
Research and development49,568 66,315 72,804 
Selling, general and administrative50,739 66,086 87,078 
Total stock-based compensation expense$108,804 $140,749 $166,950 
v3.25.4
Employee Benefit Plans
12 Months Ended
Dec. 31, 2025
Retirement Benefits [Abstract]  
Employee Benefit Plans Employee Benefit Plans
The Company has made available to all full-time United States employees a 401(k) retirement savings plan. Under this plan, employee and employer contributions and accumulated plan earnings qualify for favorable tax treatment under Section 401(k) of the Internal Revenue Code. The Company matches 100% of the first 3% of the employee's eligible compensation, up to a maximum of two thousand dollars annually per employee. The Company contributed $1.9 million, $1.9 million, and $1.8 million for the years ended December 31, 2025, 2024, and 2023 respectively.
v3.25.4
Net Loss Per Share
12 Months Ended
Dec. 31, 2025
Earnings Per Share [Abstract]  
Net Loss Per Share Net Loss Per Share
The following outstanding shares of common stock equivalents were excluded from the computation of diluted net loss per share for the periods presented because including them would have had an anti-dilutive effect:
Year Ended December 31,
202520242023
Restricted stock units7,826,741 6,493,387 5,334,134 
Stock options to purchase common stock3,561,297 4,594,582 5,946,786 
Shares committed under ESPP59,520 124,652 48,302 
Total11,447,558 11,212,621 11,329,222 
v3.25.4
Insider Trading Arrangements
3 Months Ended
Dec. 31, 2025
shares
Trading Arrangements, by Individual  
Non-Rule 10b5-1 Arrangement Adopted false
Rule 10b5-1 Arrangement Terminated false
Non-Rule 10b5-1 Arrangement Terminated false
Sarah Teichmann [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement On November 26, 2025, Sarah Teichmann, a member of our Board of Directors, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 7,579 shares of the Company’s common stock, subject to certain conditions. The expiration date of the trading arrangement is February 25, 2027.
Name Sarah Teichmann
Title member of our Board of Directors
Rule 10b5-1 Arrangement Adopted true
Adoption Date November 26, 2025
Expiration Date February 25, 2027
Arrangement Duration 456 days
Aggregate Available 7,579
Serge Saxonov [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
On November 29, 2025, Serge Saxonov, Chief Executive Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 100,000 shares of the Company’s common stock plus up to the number of net shares Dr. Saxonov receives upon vesting in 114,237 restricted stock units scheduled to vest during the term of the arrangement, subject to certain conditions. The expiration date of the trading arrangement is February 26, 2027.
Name Serge Saxonov
Title Chief Executive Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date November 29, 2025
Expiration Date February 26, 2027
Arrangement Duration 454 days
Serge Saxonov, Common Stock [Member] | Serge Saxonov [Member]  
Trading Arrangements, by Individual  
Aggregate Available 100,000
Serge Saxonov, Restricted Stock Units [Member] | Serge Saxonov [Member]  
Trading Arrangements, by Individual  
Aggregate Available 114,237
v3.25.4
Insider Trading Policies and Procedures
12 Months Ended
Dec. 31, 2025
Insider Trading Policies and Procedures [Line Items]  
Insider Trading Policies and Procedures Adopted true
v3.25.4
Cybersecurity Risk Management and Strategy Disclosure
12 Months Ended
Dec. 31, 2025
Cybersecurity Risk Management, Strategy, and Governance [Line Items]  
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
We have developed and implemented a cybersecurity risk management program intended to protect the confidentiality, integrity and availability of our critical systems and information.
We design and assess our program based on the Center For Internet Security (“CIS”) Controls. While this does not imply that we meet any particular technical standards, specifications or requirements, we use the CIS Controls framework as a guide to help us identify, assess and manage cybersecurity risks relevant to our business.
Our cybersecurity risk management program is integrated into our overall risk management program which includes insurance coverage for cybersecurity incidents and shares common methodologies, reporting channels and governance processes that apply across the risk management program to other legal, compliance, strategic, operational and financial risk areas.
Key elements of our cybersecurity risk management program include, but are not limited to, the following:
risk assessments designed to help identify material risks from cybersecurity threats to our critical systems and information;
a security team principally responsible for managing (1) our cybersecurity risk assessment processes, (2) our security controls and (3) our response to cybersecurity incidents;
the use of external service providers, where appropriate, to assess, test or otherwise assist with aspects of our security processes;
cybersecurity awareness training of our employees, including incident response personnel and senior management;
a cybersecurity incident response plan that includes procedures for responding to cybersecurity incidents; and
a third-party risk management process for key service providers based on our assessment of their criticality to our operations and respective risk profile.
We have not identified risks from known cybersecurity threats, including as a result of any prior cybersecurity incidents, that have materially affected us, including our operations, business strategy, results of operations, or financial condition. We face risks from cybersecurity threats that, if realized, are reasonably likely to materially affect us, including our operations, business strategy, results of operations or financial condition.
For more information, see the section titled “Risk Factor—Risks related to our intellectual property, information technology and data security—If we or our critical third-party providers experience a significant disruption in our information technology systems or breaches of data security, our business could be adversely affected.
Cybersecurity Risk Management Processes Integrated [Flag] true
Cybersecurity Risk Management Processes Integrated [Text Block]
We design and assess our program based on the Center For Internet Security (“CIS”) Controls. While this does not imply that we meet any particular technical standards, specifications or requirements, we use the CIS Controls framework as a guide to help us identify, assess and manage cybersecurity risks relevant to our business.
Our cybersecurity risk management program is integrated into our overall risk management program which includes insurance coverage for cybersecurity incidents and shares common methodologies, reporting channels and governance processes that apply across the risk management program to other legal, compliance, strategic, operational and financial risk areas.
Cybersecurity Risk Management Third Party Engaged [Flag] true
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag] true
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag] false
Cybersecurity Risk Board of Directors Oversight [Text Block]
Our Board considers cybersecurity risk as part of its risk oversight function and has delegated to the Audit Committee oversight of cybersecurity and other information technology risks, including management’s implementation of our cybersecurity risk management program.
The Audit Committee receives regular reports from management on our cybersecurity risks, including written reports. In addition, management updates the Audit Committee regarding any cybersecurity incidents it considers to be significant or potentially significant.
The Audit Committee reports to the full Board regarding its activities, including those related to cybersecurity.
Our management team, including our General Counsel, President and Chief Financial Officer, is responsible for assessing and managing our material risks from cybersecurity threats. The team has primary responsibility for our overall cybersecurity risk management program and supervises both our internal cybersecurity personnel and our external cybersecurity consultants. Team members who support our information security program have relevant educational and industry experience, including holding similar positions at large technology companies.
Our management team takes steps to stay informed about and monitor efforts to prevent, detect, mitigate and remediate cybersecurity risks and incidents through various means, which may include briefings from internal security personnel; threat
intelligence and other information obtained from governmental, public or private sources, including external consultants engaged by us; and alerts and reports produced by security tools deployed in our information technology environment.
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block] Our Board considers cybersecurity risk as part of its risk oversight function and has delegated to the Audit Committee oversight of cybersecurity and other information technology risks, including management’s implementation of our cybersecurity risk management program.
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
The Audit Committee receives regular reports from management on our cybersecurity risks, including written reports. In addition, management updates the Audit Committee regarding any cybersecurity incidents it considers to be significant or potentially significant.
The Audit Committee reports to the full Board regarding its activities, including those related to cybersecurity.
Cybersecurity Risk Role of Management [Text Block]
Our management team, including our General Counsel, President and Chief Financial Officer, is responsible for assessing and managing our material risks from cybersecurity threats. The team has primary responsibility for our overall cybersecurity risk management program and supervises both our internal cybersecurity personnel and our external cybersecurity consultants. Team members who support our information security program have relevant educational and industry experience, including holding similar positions at large technology companies.
Our management team takes steps to stay informed about and monitor efforts to prevent, detect, mitigate and remediate cybersecurity risks and incidents through various means, which may include briefings from internal security personnel; threat
intelligence and other information obtained from governmental, public or private sources, including external consultants engaged by us; and alerts and reports produced by security tools deployed in our information technology environment.
Cybersecurity Risk Management Positions or Committees Responsible [Flag] true
Cybersecurity Risk Management Positions or Committees Responsible [Text Block] Audit Committee oversight of cybersecurity and other information technology risks, including management’s implementation of our cybersecurity risk management program.
Cybersecurity Risk Management Expertise of Management Responsible [Text Block] Team members who support our information security program have relevant educational and industry experience, including holding similar positions at large technology companies.
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Our management team, including our General Counsel, President and Chief Financial Officer, is responsible for assessing and managing our material risks from cybersecurity threats. The team has primary responsibility for our overall cybersecurity risk management program and supervises both our internal cybersecurity personnel and our external cybersecurity consultants. Team members who support our information security program have relevant educational and industry experience, including holding similar positions at large technology companies.
Our management team takes steps to stay informed about and monitor efforts to prevent, detect, mitigate and remediate cybersecurity risks and incidents through various means, which may include briefings from internal security personnel; threat
intelligence and other information obtained from governmental, public or private sources, including external consultants engaged by us; and alerts and reports produced by security tools deployed in our information technology environment.
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag] true
v3.25.4
Summary of Significant Accounting Policies (Policies)
12 Months Ended
Dec. 31, 2025
Accounting Policies [Abstract]  
Basis of Presentation
Basis of Presentation
The consolidated financial statements, which include the Company’s accounts and the accounts of its wholly-owned subsidiaries, are prepared in accordance with U.S. generally accepted accounting principles (or “GAAP”). All intercompany transactions and balances have been eliminated.
Use of Estimates
Use of Estimates
The preparation of financial statements in conformity with GAAP requires management to make judgments, estimates and assumptions that affect the reported amounts of assets and liabilities at the date of the financial statements, disclosure of contingent liabilities, and the reported amounts of revenue and expense. These judgments, estimates and assumptions are used for, but not limited to, revenue recognition, inventory valuation and write-downs, accounting for asset and business acquisitions, the valuation of stock-based compensation awards and remeasurement of contingent consideration. The Company bases its estimates on various factors and information, which may include, but are not limited to, history and prior experience, the Company’s forecasts and future plans, current economic conditions and information from third-party professionals that management believes to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities and recorded amounts of expenses that are not readily apparent from other sources. To the extent there are material differences between the Company’s estimates and the actual results, the Company’s future consolidated results of operation may be affected.
Segment Information
Segment Information
The Company operates as a single operating segment. The Company’s chief operating decision maker (“CODM”), its Chief Executive Officer, manages the Company’s operations on a consolidated basis for the purposes of allocating resources, making operating decisions and evaluating financial performance. The measures of profitability and significant segment expenses reviewed by the CODM are consistent with the presentation and disclosure in these consolidated financial statements.
Cash and Cash Equivalents
Cash and Cash Equivalents
The Company considers all highly liquid investments with an original maturity of three months or less from the date of purchase to be cash equivalents. Cash equivalents consist of amounts invested in money market funds and are stated at fair value.
Marketable Securities
Marketable Securities
The Company designates investments in debt securities as available-for-sale. Available-for-sale debt securities with original maturities of three months or less from the date of purchase are classified within cash and cash equivalents. Available-for-sale debt securities with original maturities longer than three months are available to fund current operations and are classified as marketable securities, within current assets on the balance sheet. Available-for-sale debt securities are reported at fair value with the related unrealized gains and losses included in "Accumulated other comprehensive income (loss)," a component of stockholders’ equity, net of tax. Realized gains (losses) on the sale of marketable securities are determined using the specific-identification method and recorded in “Other income (expense), net,” in the Company’s consolidated statements of operations.
The available-for-sale debt securities are subject to a periodic impairment review. For investments in an unrealized loss position, the Company determines whether a credit loss exists by considering information about the collectability of the instrument, current market conditions and reasonable and supportable forecasts of economic conditions. The Company recognizes an allowance for credit losses, up to the amount of the unrealized loss when appropriate, and writes down the amortized cost basis of the investment if it is more likely than not that the Company will be required or will intend to sell the investment before recovery of its amortized cost basis. Allowances for credit losses and write-downs are recognized in “Other income (expense), net,” and unrealized losses not related to credit losses are recognized in “Other comprehensive income (loss).” There are no allowances for credit losses for the periods presented.
Fair Value of Financial Instruments
Fair Value of Financial Instruments
Cash equivalents are comprised of money market funds which are classified as Level 1 in the fair value hierarchy. Assets recorded at fair value on a recurring basis in the balance sheets are categorized based upon the level of judgment associated with the inputs used to measure their fair values. Fair value is defined as the exchange price that would be received for an asset in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. The authoritative guidance on fair value measurements establishes a three-tier fair value hierarchy for disclosure of fair value measurements as follows:
Level 1 - Inputs are unadjusted, quoted prices in active markets for identical assets or liabilities at the measurement date;
Level 2 - Inputs are observable, unadjusted quoted prices in active markets for similar assets or liabilities, unadjusted quoted prices for identical or similar assets or liabilities in markets that are not active, or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the related assets or liabilities; and
Level 3 - Unobservable inputs that are significant to the measurement of the fair value of the assets or liabilities that are supported by little or no market data.
The Company’s financial instruments consist of Level 1 and Level 2 assets. Where quoted prices are available in an active market, securities are classified as Level 1. Money market funds are classified as Level 1. Level 2 assets include corporate bonds, asset-backed securities, commercial paper, U.S. Government Treasury and agency securities, and debt securities in government-sponsored entities based upon quoted market prices for similar movements in active markets, quoted prices for identical or similar instruments in markets that are not active and model-based valuation techniques for which all significant inputs are observable in the market or can be corroborated by observable market data for substantially the full term of the assets. Where applicable, these models project future cash flows and discount the future amounts to a present value using market-based observable inputs obtained from various third party-data providers, including but not limited to, benchmark yields, interest rate curves, reported trades, broker/dealer quotes and reference data.
The Company measures contingent consideration related to the Company’s acquisition of Scale Biosciences, Inc. (“Scale Bio”) at fair value on a recurring basis. Refer to Note 4, Acquisitions, for additional details regarding the acquisition. The contingent consideration is valued using a probability-weighted discounted cash flow approach, which reflects management’s estimates of future outcomes, timing of payments and discount rates. Because these inputs involve significant judgment, the fair value measurement are classified as Level 3 within the fair value hierarchy.
Accounts Receivable, Net
Accounts Receivable, Net
Accounts receivable consist of amounts due from customers for the sales of products and services. The Company reviews its accounts receivable and provides allowances of specific amounts if collectability is no longer reasonably assured based on historical experience and specific customer collection issues.
Business Concentrations
Business Concentrations
The Company’s instruments are mostly assembled and tested by third party contract manufacturers in Asia and the United States. The Company’s agreement with the contract manufacturers contains purchase commitments. In addition, the Company relies on several suppliers for key components for its reagent kits. A significant disruption in the operations of the contract manufacturers or suppliers may impact the production of the Company’s products for a substantial period of time, which could have a material adverse effect on its business, financial condition and results of operations.
Concentrations
Concentrations
Financial instruments that potentially subject the Company to credit risk consist of cash equivalents, marketable securities, accounts receivable and other receivables. The Company’s cash and cash equivalents held with large financial institutions in the United States and deposits exceed the Federal Deposit Insurance Corporation’s insurance limit. The Company performs periodic evaluations of the risks associated with its investments and the relative credit standing of these financial institutions.
The Company performs ongoing credit evaluations of its customers’ financial condition. The Company does not require collateral from its customers but may require upfront payments from certain customers. The Company has not experienced material credit losses to date.
Inventory
Inventory
Inventory is recorded at the lower of cost, determined on a first-in, first-out basis, or net realizable value. The Company uses judgment to analyze and determine if the composition of its inventory is obsolete, slow-moving, unsalable or otherwise carried above the net realizable value and frequently reviews such determinations. The Company writes down specifically identified unusable, obsolete, slow-moving or known unsalable inventory and inventory otherwise carried above the net realizable value in the period that it is first recognized by using a number of factors including product expiration dates, open and unfulfilled orders and sales forecasts. Net realizable value is determined using the estimated selling prices in the ordinary course of business, less reasonably predictable costs of completion, disposal and transportation. Any write-down of its inventory to net realizable value establishes a new cost basis and will be maintained even if certain circumstances suggest that the inventory is recoverable in subsequent periods. Costs associated with the write-down of inventory are recorded to cost of revenue on the Company’s consolidated statements of operations.
Leases
Leases
The Company determines if an arrangement is or contains a lease at inception by assessing whether the arrangement contains an identified asset and whether it has the right to control the identified asset. Right-of-use (“ROU”) assets represent the Company’s right to use an underlying asset for the lease term and lease liabilities represent the Company’s obligation to make lease payments arising from the lease. Lease liabilities are recognized at the lease commencement date based on the present value of future lease payments over the lease term. ROU assets are based on the measurement of the lease liability and also include any lease payments made prior to or on lease commencement and exclude lease incentives and initial direct costs incurred, as applicable.
The Company uses its incremental borrowing rate based on the information available at the lease commencement date in determining the present value of future lease payments. The Company gives consideration to its credit risk, term of the lease and total lease payments and adjusts for the impacts of collateral, as necessary, when calculating its incremental borrowing rates. The lease terms may include options to extend or terminate the lease when the Company is reasonably certain it will exercise such options. Lease costs for the Company’s operating leases are recognized on a straight-line basis within operating expenses and costs of goods sold over the reasonably assured lease term.
The Company evaluates ROU assets related to leases for indicators of impairment whenever events or changes in circumstances indicate that the carrying amount of an ROU asset may not be recoverable. This evaluation is performed in a manner consistent with the Company’s impairment assessment for long-lived assets. When a decision has been made to sublease that space, the Company evaluates the asset for impairment and recognize the associated impact to the ROU asset and related expense, if applicable. The evaluation is performed at the lowest level of identifiable cash flows for an asset group. Undiscounted cash flows expected to be generated by the related ROU assets are estimated over the ROU assets’ useful lives. If the evaluation indicates that the carrying amount of the ROU assets may not be recoverable, any potential impairment is measured based upon the fair value of the related ROU asset or asset group as determined by appropriate valuation techniques. During the year ended December 31, 2025, the Company recognized an impairment loss related to the ROU assets associated with the leased facility acquired as part of the Scale Bio acquisition. Refer to the Impairment of Long-Lived Assets section below and Note 7, Commitments and Contingencies - Lease Agreements, for further details.
The Company has elected to not separate lease and non-lease components for any leases within its existing classes of assets and, as a result, accounts for any lease and non-lease components as a single lease component. The Company has also elected to not apply the recognition requirement to any leases within its existing classes of assets with a term of 12 months or less.
Property and Equipment, Net
Property and Equipment, Net
Property and equipment is stated at cost, net of accumulated depreciation.
Acquisitions of Intellectual Property
Acquisitions of Intellectual Property
The Company evaluates acquisitions of assets and other similar transactions to assess whether or not the transaction should be accounted for as a business combination or asset acquisition by first applying a screen test to determine if substantially all of the fair value of the gross assets acquired is concentrated in a single identifiable asset or group of similar identifiable assets. If the screen test is met, the transaction is accounted for as an asset acquisition. If the screen test is not met, further determination is required as to whether or not the Company has acquired inputs and processes that have the ability to create outputs, which would meet the requirements of a business.
The Company accounts for asset acquisition under Accounting Standards Codification, Business Combinations, Topic 805, Subtopic 50, which requires the acquiring entity in an asset acquisition to recognize net assets based on the cost to the acquiring entity on a relative fair value basis, which includes transaction costs in addition to consideration given. Goodwill is not recognized in an asset acquisition and any excess consideration transferred over the fair value of the net assets acquired is allocated to the non-monetary identifiable assets based on relative fair values.
If the Company has the option to pay in equity for contingent consideration related to the acquisition, a liability is recorded in accordance with the guidance of ASC 480, Distinguishing Liabilities from Equity. The contingent consideration is recorded at fair value at inception and is revalued on a quarterly basis for any significant adjustments and recognized in the Company’s consolidated statements of operations in “Other income (expense), net.”
Impairment of Long-Lived Assets
Impairment of Long-Lived Assets
The Company evaluates long-lived assets, such as property and equipment and intangible assets, for impairment whenever events or changes in circumstances indicate that the carrying value of an asset may not be recoverable. If indicators of impairment exist and the undiscounted future cash flows that the assets are expected to generate are less than the carrying value of the assets, the Company reduces the carrying amount of the assets to their estimated fair values based on a discounted cash flow approach or, when available and appropriate, to comparable market values.
Product Warranties
Product Warranties
The Company generally provides a one-year warranty on its instruments. The Company reviews its exposure to estimated warranty obligations associated with instrument sales and establishes an accrual based on historical product failure rates and actual warranty costs incurred. This expense is recorded as a component of cost of revenue in the consolidated statements of operations.
Deferred Revenue
Deferred Revenue
Deferred revenue consists of payments received in advance of revenue recognition primarily related to instrument service agreements, also referred to as extended warranties. Revenue under these agreements is recognized ratably over the related service
period. Deferred revenue expected to be recognized during the 12 months following the balance sheet date is recorded as current portion of deferred revenue and the remaining portion is recorded as long-term.
Revenue Recognition
Revenue Recognition
Products and Services Revenue
The Company generates revenue from sales of products, which consist of instruments and consumables, and services. Revenue from product sales is recognized when control of the product is transferred, which is generally upon shipment to the customer. Instrument service agreements, which relate to extended warranties, are typically entered into for a one-year term, following the expiration of the standard one-year warranty period. Revenue for extended warranties is recognized ratably over the term of the extended warranty period as a stand ready performance obligation. Revenue is recorded net of discounts, distributor commissions and sales taxes collected on behalf of governmental authorities. Customers are invoiced generally upon shipment, or upon order for services, and payment is typically due within 30 days. Cash received from customers in advance of product shipments or the provision of services is recorded as a contract liability. The Company’s contracts with its customers generally do not include rights of return or a significant financing component.
The Company regularly enters into contracts that include various combinations of products and services which are generally distinct and accounted for as separate performance obligations. The transaction price is allocated to each performance obligation in proportion to its standalone selling price. The Company determines standalone selling price using average selling prices with consideration of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, the Company relies upon prices set by management, adjusted for applicable discounts.
License and Royalty Revenue
The Company has agreements with third parties that include up-front fees and royalties. Revenue related to the delivery of intellectual property is recognized when the license is delivered to the third parties. Royalty revenue is recognized when the underlying sales occur. If the reporting of the actual sales from the Company’s licensees occurs after the Company’s reporting date, the Company estimates the royalty revenue receivable at the reporting date and adjusts for any changes in estimates in the following period.
Cost of Products and Services Revenue
Cost of Products and Services Revenue
Cost of product and services revenue primarily consists of manufacturing costs incurred in the production process, including personnel and related costs, component materials, labor and overhead, packaging and delivery costs and allocated costs including facilities and information technology. In addition, cost of product and services revenue includes royalty costs for licensed technologies included in the Company’s products, warranty costs and write-downs for slow-moving and obsolete inventory.
Shipping and Handling Costs
Shipping and Handling Costs
Shipping and handling charged to customers are recorded as revenue. Shipping and handling costs are included in the Company’s cost of revenue.
Research and Development
Research and Development
Research and development costs are expensed in the period incurred. Research and development expense consists of personnel and related costs, independent contractor costs, laboratory supplies, equipment maintenance, prototype and materials expenses, amortization of developed technology and intangibles and allocated costs including facilities and information technology.
Advertising Costs
Advertising Costs
Advertising costs are expensed as incurred.
Stock-Based Compensation
Stock-Based Compensation
The Company’s stock-based compensation expense relates to stock options, restricted stock units (“RSUs”), performance stock units (“PSUs”), market-based performance stock awards ("PSAs") including performance stock options and performance RSUs granted pursuant to equity incentive plans, and stock purchase rights under an Employee Stock Purchase Plan (“ESPP”). Stock-based compensation expense for its stock-based awards is based on their grant date fair value. The Company determines the fair value of RSUs based on the closing price of its stock, which is listed on the Nasdaq Global Select Market, at the date of the
grant (or on the most recent trading day prior to grant, if the date of grant is not a trading day). The Company estimates the fair value of stock option awards under an equity incentive plan and stock purchase rights under an ESPP on the grant date using the Black-Scholes option-pricing model. The fair values of stock-based awards excluding PSUs and PSAs are recognized as compensation expense on a straight-line basis over the requisite service period in which the awards are expected to vest and forfeitures are recognized as they occur.
The Black-Scholes model considers several variables and assumptions in estimating the fair value of stock-based awards. These variables include the per share fair value of the underlying common stock, exercise price, expected term, risk-free interest rate, expected annual dividend yield and the expected stock price volatility over the expected term. The Company calculated the expected term using the simplified method, which is the mid-point between the vesting and contractual term. Due to the short trading period of the Company's stock, the Company has estimated volatility by reference to the historical volatilities of the Company and that of similar publicly traded peer companies. The risk-free interest rate is based on the yield available on U.S. Treasury zero-coupon issues similar in duration to the expected term of the equity-settled award.
For PSAs, the Company derives the valuation of the award and the requisite service period for each separately vesting portion of the award using a Monte Carlo simulation model and the related compensation expense is recognized over the derived service period using the accelerated attribution method commencing on the grant date. The derived service period is the median duration of the successful stock price paths to meet the respective escalating stock price thresholds as simulated in the Monte Carlo valuation model which uses assumptions such as volatility, risk-free interest rate, cost of equity and dividend estimated for the performance period of the PSAs. If the related market condition is achieved earlier than its estimated derived service period, the stock-based compensation expense will be accelerated, and a cumulative catch-up expense will be recorded during the period in which the market condition is met.
For PSUs, management reassesses the probability of vesting at each reporting period, and any changes in estimates are recognized on a cumulative catch-up basis for the stock-based compensation expense.
Foreign Currency
Foreign Currency
For foreign subsidiaries where the functional currency is the local currency, assets and liabilities are translated to the U.S. dollar using month-end exchange rates, and revenue and expenses using average exchange rates. The adjustments resulting from these foreign currency translations are recorded in “Accumulated other comprehensive income (loss).”
For entities where the functional currency is the U.S. dollar, monetary assets and liabilities are remeasured using exchange rates in effect at the balance sheet dates and non-monetary assets and liabilities are remeasured at historical exchange rates. Revenue and expenses are remeasured at the average exchange rates for the period. Gains or losses from foreign currency remeasurement are included in “Other income (expense), net” in the consolidated statements of operations.
Income Taxes
Income Taxes
The Company uses the asset and liability method of accounting for income taxes, in which deferred tax assets and liabilities are recognized for the future tax consequences attributable to the differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets and liabilities are measured using the enacted tax rates expected to apply in the years in which those tax assets and liabilities are expected to be realized. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the period that includes the enactment date. A valuation allowance is established if it is more likely than not that all or a portion of the deferred tax asset will not be realized.
The Company’s tax positions are subject to income tax audits. The Company recognizes the tax benefit of an uncertain tax position only if it is more likely than not that the position is sustainable upon examination by the taxing authority, based on the technical merits. The tax benefit recognized is measured as the largest amount of benefit which is more likely than not (greater than 50% likely) to be realized upon settlement with the taxing authority. The Company recognizes interest accrued and penalties related to unrecognized tax benefits in its tax provision.
The Company calculates the current and deferred income tax provision based on estimates and assumptions that could differ from the actual results reflected in income tax returns filed in subsequent years. Adjustments based on filed income tax returns are recorded when identified. The amount of income tax paid is subject to examination by U.S. and foreign tax authorities. The estimate of the potential outcome of any uncertain tax issue is subject to management’s assessment of the relevant risks, facts and circumstances existing at that time. To the extent the assessment of such tax position changes, the change in estimate is recorded in the period in which the determination is made.
Net Loss Per Share
Net Loss Per Share
Net loss per share is computed using the two-class method required for multiple classes of common stock and participating securities. The rights, including the liquidation and dividend rights and sharing of losses, of the Class A common stock and
Class B common stock are identical, other than voting rights. As the liquidation and dividend rights and sharing of losses are identical, the undistributed earnings are allocated on a proportionate basis and the resulting net loss per share will, therefore, be the same for both Class A and Class B common stock on an individual or combined basis.
Basic net loss per share is computed by dividing net loss by the weighted-average number of shares of common stock outstanding during the period, adjusted for outstanding shares that are subject to repurchase.
For the calculation of diluted net loss per share, basic net loss per share is adjusted by the effect of dilutive securities including awards under the Company’s equity compensation plans. Diluted net loss per share is computed by dividing net loss by the weighted-average number of dilutive shares of common stock outstanding. For periods in which the Company reports net losses, diluted net loss per share is the same as basic net loss per share because potentially dilutive shares of common stock are not assumed to have been issued if their effect is anti-dilutive.
Recently Issued Accounting Pronouncement and Disclosure Rules
Recently Issued Accounting Pronouncement and Disclosure Rules
In December 2023, the Financial Accounting Standards Board (“FASB”) issued Accounting Standard Update (“ASU”) No. 2023-09, Income Taxes (“ASU No. 2023-09”), which prescribes standardized categories and disaggregation of information in the reconciliation of provision for income taxes, requires disclosure of disaggregated income taxes paid, and modifies other income tax-related disclosure requirements. The updated standard is effective beginning with the Company’s fiscal year 2025 annual reporting period. The Company adopted ASU No. 2023-09 in its fourth quarter of 2025 using a prospective transition method and the additional disclosures required under the standard are included in the Company’s financial statement disclosures.
In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses ("ASU 2024-03"), and in January 2025 issued ASU 2025-01, Clarifying the Effective Date ("ASU 2025-01") to provide clarification as to the effective date. ASU 2024-03 requires disaggregated disclosure of income statement expenses. ASU 2024-03 does not change the expense captions currently presented on the income statement; rather it requires disaggregation of certain expense captions into specified categories in disclosures within the footnotes to the financial statements. ASU 2024-03, as amended by ASU 2025-01, is effective for annual reporting periods beginning after December 15, 2026, and interim reporting periods within fiscal years beginning after December 15, 2027. ASU 2024-03 can be applied on a prospective basis; however, retrospective application is permitted. Early adoption is permitted. As ASU 2024-03 only requires additional disclosure, it will not have a material impact on the Company's financial condition and results of operations.
v3.25.4
Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2025
Accounting Policies [Abstract]  
Schedule of Property Equipment Depreciation is computed using the straight-line method based on the estimated useful lives of the following assets:
Useful Life (Years)
Building3-40
Laboratory equipment and machinery 2-5
Computer equipment2-5
Furniture and fixtures3
Leasehold improvements3-10
Property and equipment, net consisted of the following (in thousands):
December 31,
20252024
Building$147,493 $147,094 
Leasehold improvements89,724 89,567 
Laboratory equipment and machinery78,133 72,498 
Land36,765 36,765 
Computer equipment and software15,281 14,953 
Furniture and fixtures9,850 9,586 
Construction in progress2,929 5,152 
Total property and equipment380,175 375,615 
Less: accumulated depreciation and amortization(153,464)(122,967)
Property and equipment, net$226,711 $252,648 
v3.25.4
Restructuring (Tables)
12 Months Ended
Dec. 31, 2025
Restructuring and Related Activities [Abstract]  
Schedule of Restructuring Costs Related to Restructuring
The following table is a summary of restructuring costs related to the Company’s restructuring activities for the years ended December 31, 2025, 2024 and 2023 (in thousands):
Termination Benefits CostsStock-Based Compensation
Expense
Long-lived Assets Impairment Expenses
Total
Balance at January 1, 2023$215 $— $— $215 
Restructuring charge310 — 2,171 2,481 
Cash payments made(215)— — (215)
Non-cash charge— — (2,171)(2,171)
Balance at December 31, 2023310 — — 310 
Restructuring charge259 — — 259 
Cash payments made(569)— — (569)
Balance at December 31, 2024— — — — 
Restructuring charge9,023 314 1,253 10,590 
Cash payments made(7,736)— — (7,736)
Non-cash charge— (314)(1,253)(1,567)
Balance at December 31, 2025$1,287 $— $— $1,287 
v3.25.4
Acquisitions (Tables)
12 Months Ended
Dec. 31, 2025
Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract]  
Schedule of Asset Acquisition, Recognized Asset Acquired and Liability Assumed
The following table summarizes the value of assets acquired and liabilities assumed (in thousands) as of the closing on August 11, 2025:
Cash$1,390 
Developed technology51,639 
Other assets and liabilities, net(6,467)
Net identifiable assets acquired$46,562 
Schedule of Asset Acquisition, Contingent Consideration
The following table discloses the summary of changes in the contingent consideration and assumed liabilities measured at fair value using Level 3 inputs (in thousands):
Year Ended December 31, 2025
Beginning of period$— 
Contingent consideration to sellers22,378 
Assumed liabilities to third parties815 
Change in fair value1,407 
Balance at end of period$24,600 
Schedule of Asset Acquisition
The following table summarizes the value of assets acquired and liabilities assumed as of the closing date (in thousands):
In-process research and development$60,980 
Intangible assets - acquired workforce200 
Property and equipment671 
Operating lease liabilities(1,496)
Other assets and liabilities, net758 
Total net assets acquired$61,113 
v3.25.4
Other Financial Statement Information (Tables)
12 Months Ended
Dec. 31, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Marketable Securities
Available-for-sale securities at December 31, 2025 consisted of the following (in thousands):
December 31, 2025December 31, 2024
Amortized CostGross Unrealized GainsGross Unrealized LossesFair ValueAmortized CostGross Unrealized GainsGross Unrealized LossesFair ValueFair Value Measurement
Cash equivalents:
Money market funds$441,108 $— $— $441,108 $322,012 $— $— $322,012 Level 1
Marketable securities:
Government debt securities49,431 12 — 49,443 49,317 18 — 49,335 Level 2
Total available-for-sale securities$490,539 $12 $— $490,551 $371,329 $18 $— $371,347 
Schedule of Inventory
Inventory was comprised of the following (in thousands):
December 31,
20252024
Finished goods$23,183 $16,736 
Work in progress17,135 27,441 
Purchased materials16,023 38,930 
Inventory$56,341 $83,107 
Schedule of Property Equipment Depreciation is computed using the straight-line method based on the estimated useful lives of the following assets:
Useful Life (Years)
Building3-40
Laboratory equipment and machinery 2-5
Computer equipment2-5
Furniture and fixtures3
Leasehold improvements3-10
Property and equipment, net consisted of the following (in thousands):
December 31,
20252024
Building$147,493 $147,094 
Leasehold improvements89,724 89,567 
Laboratory equipment and machinery78,133 72,498 
Land36,765 36,765 
Computer equipment and software15,281 14,953 
Furniture and fixtures9,850 9,586 
Construction in progress2,929 5,152 
Total property and equipment380,175 375,615 
Less: accumulated depreciation and amortization(153,464)(122,967)
Property and equipment, net$226,711 $252,648 
Schedule of Intangible Assets Net
Intangible assets, net consisted of the following (dollars in thousands):
December 31, 2025December 31, 2024
Remaining Useful Life in YearsGross
Carrying
Amount
Accumulated
Amortization
Intangibles,
Net
Gross
Carrying
Amount
Accumulated
Amortization
Intangibles,
Net
Developed technology6.0$52,639 $(3,359)$49,280 $1,000 $(92)$908 
Technology licenses8.822,504 (9,491)13,013 22,504 (8,016)14,488 
Assembled workforce0.51,328 (1,292)36 1,328 (1,080)248 
Customer relationships0.0945 (945)— 945 (918)27 
Intangible assets, net$77,416 $(15,087)$62,329 $25,777 $(10,106)$15,671 
Schedule of Annual Amortization of Intangible Assets
The estimated annual amortization of intangible assets for the next five years is shown below (in thousands):
Estimated
Annual
Amortization
2026$9,644 
20279,609 
20289,609 
20299,608 
20309,569 
Thereafter14,290 
Total$62,329 
Schedule of Accrued Compensation and Related Benefits
Accrued compensation and related benefits were comprised of the following (in thousands):
December 31,
20252024
Accrued bonus$29,506 $21,859 
Accrued commissions5,335 5,938 
Accrued payroll and related costs4,964 2,970 
Other2,695 2,848 
Accrued compensation and related benefits$42,500 $33,615 
Schedule of Accrued Expense and Other Current Liabilities
Accrued expenses and other current liabilities were comprised of the following (in thousands):
December 31,
20252024
Taxes payable$7,219 $4,936 
Product warranties6,828 8,615 
Customer refunds and deposits payable5,542 3,002 
Accrued royalties for licensed technologies4,971 7,042 
Accrued professional services2,914 5,315 
Accrued legal and related costs1,502 6,100 
Accrued property and equipment124 644 
Other10,871 5,511 
Accrued expenses and other current liabilities$39,971 $41,165 
Schedule of Changes in the Reserve for Product Warranties
Changes in the reserve for product warranties were as follows (in thousands):
Year Ended December 31,
20252024
Beginning of period$8,615 $8,116 
Amounts charged to cost of revenue8,567 13,325 
Repairs and replacements(10,354)(12,826)
End of period$6,828 $8,615 
Schedule of Revenue of Recognized in Contract Liabilities
Year Ended December 31,
20252024
Beginning of period$33,171 $21,964 
Revenue recognized that was included in the contract liability at the beginning of the year(20,130)(11,407)
Revenue deferred excluding amounts recognized as revenue during the period21,362 22,614 
End of period$34,403 $33,171 
Schedule of Revenue by Source
The following table represents revenue by source for the periods indicated (in thousands). Spatial products include the Company’s Visium and Xenium products:
Year Ended December 31,
202520242023
Instruments
Single Cell$22,671 $35,212 $47,866 
Spatial34,108 57,503 75,605 
Total instruments revenue56,779 92,715 123,471 
Consumables
Single Cell363,206 372,308 420,316 
Spatial143,977 121,124 59,237 
Total consumables revenue507,183 493,432 479,553 
Services32,726 24,317 15,703 
Products and services revenue596,688 610,464 618,727 
License and royalty revenue46,135 321 — 
Total revenue$642,823 $610,785 $618,727 
Schedule of Revenue by Geography
The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):
Year Ended December 31,
202520242023
Americas
United States (a)
$346,512 $334,318 $360,091 
Americas (excluding United States)12,261 13,447 13,101 
Total Americas358,773 347,765 373,192 
Europe, Middle East and Africa161,716 159,762 142,276 
Asia-Pacific
China70,264 57,300 50,965 
Asia-Pacific (excluding China)52,070 45,958 52,294 
Total Asia-Pacific122,334 103,258 103,259 
Total revenue$642,823 $610,785 $618,727 
__________________________
(a) Includes license and royalty revenue.
v3.25.4
Income Tax (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Income (Loss) Before Income Tax, Domestic and Foreign
Income (loss) before provision for income taxes were as follows (in thousands):
Year Ended December 31,
202520242023
United States$(44,598)$(187,720)$(263,292)
International4,691 10,020 14,529 
Total$(39,907)$(177,700)$(248,763)
Schedule of Provision for Income Taxes
The provision for income taxes consisted of the following (in thousands):
Year Ended December 31,
202520242023
Current provision:
Federal$(7)$396 $351 
State397 314 180 
Foreign3,557 3,508 6,252 
Total current provision for income taxes3,947 4,218 6,783 
Deferred provision:
Federal— — — 
State— — — 
Foreign(310)709 (447)
Total deferred provision for income taxes(310)709 (447)
Provision for income taxes$3,637 $4,927 $6,336 
Schedule of Effective Income Tax Rate Reconciliation
A reconciliation of the federal statutory income tax provision to the effective income tax provision is as follows (in thousands):
Year Ended December 31, 2025
AmountPercent
U.S. federal statutory tax rate$(8,380)21 %
State and local income taxes, net of federal income tax effect (a)
(2,363)%
Foreign tax effects
Singapore
Nondeductible compensation1,179 (3)%
Other(248)%
Other foreign jurisdictions274 (1)%
Effect of cross-border tax laws336 (1)%
Tax credits
   Research and development tax credits(4,250)11 %
Changes in valuation allowance(5,038)13 %
Nontaxable or nondeductible items
   Stock-based compensation14,551 (37)%
Executive compensation (162(m))1,208 (3)%
   Other items503 (1)%
Changes in unrecognized tax benefits5,865 (15)%
Effective tax rate$3,637 (9)%
___________________
(a) State taxes in California, Pennsylvania and Texas made up the majority (greater than 50 percent) of the tax effect in this category.

Year Ended December 31,
20242023
Income tax provision at federal statutory rate$(37,317)$(52,240)
State taxes, net of federal benefit(11,938)(14,831)
Tax credits(8,895)(14,551)
Foreign taxes2,148 3,888 
Stock-based compensation15,978 2,422 
Change in valuation allowance36,378 79,551 
Acquisition related expenses— 2,296 
Waived deductions under Section 59A8,190 — 
Other383 (199)
Total provision for income taxes$4,927 $6,336 
Schedule of Deferred Tax Assets and Liabilities The major components of deferred tax assets and liabilities are as follows (in thousands):
Year Ended December 31,
20252024
Deferred tax assets
Net operating loss carryforwards$202,704 $161,681 
Research and development tax credits111,143 103,555 
Accruals and reserves17,323 12,302 
Operating lease liability19,441 19,628 
Intangibles27,845 35,966 
Stock-based compensation24,383 26,772 
Capitalized research and development
103,001 136,267 
Total deferred tax assets505,840 496,171 
Valuation allowance(490,154)(479,452)
Net deferred tax assets15,686 16,719 
Deferred tax liabilities
Property and equipment(2,855)(4,124)
Operating right-of-use assets(13,436)(13,510)
Total deferred tax liabilities(16,291)(17,634)
Net deferred tax liabilities$(605)$(915)
Schedule of Cash Flow, Supplemental Disclosures
Income taxes paid, net of refunds received, consisted of the following (in thousands):
Year Ended December 31, 2025
AmountPercent
State$195 %
Foreign
Singapore947 40 %
Other foreign jurisdictions1,249 52 %
Total income taxes paid, net of refunds received$2,391 100 %
Schedule of Unrecognized Tax Benefits Roll Forward
The total balance of unrecognized gross tax benefits, resulting primarily from research and development tax credits claimed on the Company’s annual tax returns, were as follows (in thousands):
20252024
Unrecognized tax benefits at beginning of year$50,022 $45,713 
Reductions related to settlements with tax authorities— (285)
Reductions based on prior year tax provisions(739)(1,617)
Additions related to acquisitions2,287 — 
Additions based on prior year tax provisions436 467 
Additions based on current year tax provisions3,484 5,744 
Unrecognized tax benefits at end of year$55,490 $50,022 
v3.25.4
Commitments and Contingencies (Tables)
12 Months Ended
Dec. 31, 2025
Commitments and Contingencies Disclosure [Abstract]  
Schedule of Company's Operating Lease Liabilities
The payments due under of the Company’s operating lease liabilities as of December 31, 2025 are as follows (in thousands):
Operating Leases
2026$15,630 
202716,805 
202816,394 
202914,800 
20309,853 
Thereafter29,537 
Total lease payments$103,019 
Less: imputed interest(18,658)
Present value of operating lease liabilities$84,361 
Operating lease liabilities, current$10,985 
Operating lease liabilities, noncurrent73,376 
Total operating lease liabilities$84,361 
Schedule of Additional Information Related to Operating Leases
The following table summarizes additional information related to the Company’s operating leases:
December 31, 2025December 31, 2024
Weighted-average remaining lease term:
Operating leases6.7 years6.8 years
Weighted-average discount rate:
Operating leases5.9 %5.8 %
v3.25.4
Capital Stock (Tables)
12 Months Ended
Dec. 31, 2025
Equity [Abstract]  
Schedule of Common Stock Issued and Outstanding
The following table represents the number of shares of Class B common stock converted to shares of Class A common stock upon the election of the holders of such shares during the years:
Year Ended December 31,
202520242023
Class B common stock converted to Class A common stock3,977,961 — 4,610,422 
v3.25.4
Equity Incentive Plans (Tables)
12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Schedule of the Company's Stock Option Activity
A summary of the Company’s stock option activity under the 2012 and 2019 Plans is as follows:
Outstanding
Options
Weighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Term
(Years)
Aggregate
Intrinsic Value
Balance as of December 31, 20244,594,582 $45.37 5.4$13,834,082 
Exercised(478,085)2.83 
Forfeited(555,200)61.62 
Balance as of December 31, 20253,561,297 $48.55 4.6$10,337,526 
Vested and exercisable as of December 31, 20253,253,508 $49.02 4.4$10,337,526 
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions
The fair value of each employee option granted in 2023 was estimated on the date of grant using the Black-Scholes option pricing model and the following assumptions for the periods indicated:
Year Ended December 31, 2023
Expected volatility
70% – 71%
Risk-free interest rate
3.7% – 4.6%
Expected term
5.3 – 6.1 years
Expected dividend—%
The Company estimated the fair values of the shares granted under the TSR component of the 2025 PSUs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2025
Expected volatility 67%
Risk-free interest rate4.0%
Expected dividend yield—%
The Company estimated the fair values of the shares granted under the TSR component of the 2024 PSUs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2024
Expected volatility 66%
Risk-free interest rate4.5%
Expected dividend yield—%
The Company estimated the fair values of shares granted under the 2023 PSAs using a Monte Carlo simulation model with the following assumptions:
Year Ended December 31, 2023
Expected volatility71%
Risk-free interest rate3.7%
Expected dividend—%
Schedule of RSU Activity
Restricted stock units (“RSUs”) activity for the year ended December 31, 2025 is as follows:
Restricted Stock
Units
Weighted-Average
Grant Date Fair Value
(per share)
Balance as of December 31, 20246,493,387 $35.55 
Granted6,184,585 10.65 
Vested(3,117,074)30.68 
Forfeited(1,734,157)27.12 
Outstanding as of December 31, 20257,826,741 $19.68 
Schedule of Fair value of the Employee Stock Purchase Plan
The following assumptions were used in estimating the fair values of shares under the ESPP:
Year Ended December 31,
202520242023
Expected volatility
67% – 75%
49% – 80%
49% – 58%
Risk-free interest rate
3.80% – 4.30%
4.44% – 5.4%
5.24% – 5.41%
Expected term (in years)
0.5
0.5
0.5
Expected dividend—%—%—%
Schedule of Recorded Stock-based Compensation Expense in the Condensed Consolidated Statement of Operations
The Company recorded stock-based compensation expense in the consolidated statement of operations for the periods presented as follows (in thousands):
Year Ended December 31,
202520242023
Cost of revenue$8,497 $8,348 $7,068 
Research and development49,568 66,315 72,804 
Selling, general and administrative50,739 66,086 87,078 
Total stock-based compensation expense$108,804 $140,749 $166,950 
v3.25.4
Net Loss Per Share (Tables)
12 Months Ended
Dec. 31, 2025
Earnings Per Share [Abstract]  
Schedule of Shares of Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share
The following outstanding shares of common stock equivalents were excluded from the computation of diluted net loss per share for the periods presented because including them would have had an anti-dilutive effect:
Year Ended December 31,
202520242023
Restricted stock units7,826,741 6,493,387 5,334,134 
Stock options to purchase common stock3,561,297 4,594,582 5,946,786 
Shares committed under ESPP59,520 124,652 48,302 
Total11,447,558 11,212,621 11,329,222 
v3.25.4
Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Millions
12 Months Ended
Dec. 31, 2025
USD ($)
segment
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Accounting Policies [Abstract]      
Number of operating segment | segment 1    
Allowance for doubtful accounts $ 0.1 $ 0.1  
Impairment long lived asset held for use statement of income or comprehensive income extensible enumeration not disclosed flag impairment charges    
Impairment of long lived assets $ 2.1 3.1 $ 9.8
Product warranty term 1 year    
Advertising costs $ 2.5 3.9 3.3
Foreign currency transaction gains $ 2.5 $ (2.1) $ 1.2
v3.25.4
Summary of Significant Accounting Policies - Schedule of Estimated Useful Life of Company Property and Equipment (Details)
Dec. 31, 2025
Building | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 3 years
Building | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 40 years
Laboratory equipment and machinery | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 2 years
Laboratory equipment and machinery | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 5 years
Computer equipment | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 2 years
Computer equipment | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 5 years
Furniture and fixtures  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 3 years
Leasehold improvements | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 3 years
Leasehold improvements | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful life of property and equipment 10 years
v3.25.4
Restructuring - Narrative (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Restructuring Cost and Reserve [Line Items]      
Restructuring charge $ 10,590 $ 259 $ 2,481
Restructuring costs     2,500
Cost of revenue      
Restructuring Cost and Reserve [Line Items]      
Restructuring costs 500    
Research And Development And Selling, General And Administrative Expenses      
Restructuring Cost and Reserve [Line Items]      
Restructuring costs     $ 2,500
Research and development      
Restructuring Cost and Reserve [Line Items]      
Restructuring costs 4,100    
Selling, general and administrative      
Restructuring Cost and Reserve [Line Items]      
Restructuring costs $ 6,000    
v3.25.4
Restructuring - Restructuring Costs Related to Restructuring (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Restructuring Reserve [Roll Forward]      
Restructuring reserve, beginning balance $ 0 $ 310 $ 215
Restructuring charge 10,590 259 2,481
Cash payments made (7,736) (569) (215)
Non-cash charge (1,567)   (2,171)
Restructuring reserve, ending balance 1,287 0 $ 310
Restructuring incurred cost statement of income or comprehensive income extensible enumeration not disclosed flag     Restructuring charge
Termination Benefits Costs      
Restructuring Reserve [Roll Forward]      
Restructuring reserve, beginning balance 0 310 $ 215
Restructuring charge 9,023 259 310
Cash payments made (7,736) (569) (215)
Non-cash charge 0   0
Restructuring reserve, ending balance 1,287 0 310
Stock-Based Compensation Expense      
Restructuring Reserve [Roll Forward]      
Restructuring reserve, beginning balance 0 0 0
Restructuring charge 314 0 0
Cash payments made 0 0 0
Non-cash charge (314)   0
Restructuring reserve, ending balance 0 0 0
Long-lived Assets Impairment Expenses      
Restructuring Reserve [Roll Forward]      
Restructuring reserve, beginning balance 0 0 0
Restructuring charge 1,253 0 2,171
Cash payments made 0 0 0
Non-cash charge (1,253)   (2,171)
Restructuring reserve, ending balance $ 0 $ 0 $ 0
v3.25.4
Acquisitions - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Aug. 11, 2025
Mar. 31, 2026
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Business Combination [Line Items]          
Change in fair value     $ 1,407 $ 0 $ 0
Asset acquisition, upfront payment     0 1,000 923
Scale BioScience Inc. Acquisition          
Business Combination [Line Items]          
Cash consideration $ 9,200        
Equity consideration $ 13,500        
Equity consideration, number of share issued (in shares) 1,099,992        
Milestone payment     30,000    
Contingent consideration attributable to sellers $ 22,400   22,378    
Change in fair value     1,407    
Cash consideration     24,600 $ 0  
Scale BioScience Inc. Acquisition | Forecast          
Business Combination [Line Items]          
Consideration transferred   $ 20,000      
2023 Acquisition          
Business Combination [Line Items]          
Consideration transferred         10,000
Asset acquisition, upfront payment         10,000
Asset acquisition, milestone payment     $ 41,300    
Cash consideration         15,000
In-process research and development         60,980
Intangible assets - acquired workforce         $ 200
v3.25.4
Acquisition - Assets Acquired and Liabilities Assumed (Detail) - Scale BioScience Inc. Acquisition
$ in Thousands
Aug. 11, 2025
USD ($)
Asset Acquisition [Line Items]  
Cash $ 1,390
Developed technology 51,639
Other assets and liabilities, net (6,467)
Net identifiable assets acquired $ 46,562
v3.25.4
Acquisition - Contingent Consideration Liability Measured at Fair Value (Details) - USD ($)
$ in Thousands
12 Months Ended
Aug. 11, 2025
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Asset Acquisition, Contingent Consideration [Roll Forward]        
Change in fair value   $ 1,407 $ 0 $ 0
Scale BioScience Inc. Acquisition        
Asset Acquisition, Contingent Consideration [Roll Forward]        
Beginning of period   0    
Contingent consideration to sellers $ 22,400 22,378    
Assumed liabilities to third parties   815    
Change in fair value   1,407    
Balance at end of period   $ 24,600 $ 0  
v3.25.4
Acquisitions - Assets Acquired and Liabilities Assumed (Details) - 2023 Acquisition
$ in Thousands
12 Months Ended
Dec. 31, 2023
USD ($)
Business Combination [Line Items]  
In-process research and development $ 60,980
Intangible assets - acquired workforce 200
Property and equipment 671
Operating lease liabilities (1,496)
Other assets and liabilities, net 758
Net identifiable assets acquired $ 61,113
v3.25.4
Other Financial Statement Information - Available-for-Sale Securities (Details) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Marketable Securities [Line Items]    
Gross Unrealized Gains $ 12 $ 18
Gross Unrealized Losses 0 0
Total available-for-sale securities, amortized cost 490,539 371,329
Total available-for-sale securities, fair value 490,551 371,347
Money market funds | Level 1    
Marketable Securities [Line Items]    
Money market funds 441,108 322,012
Government debt securities | Level 2    
Marketable Securities [Line Items]    
Total marketable securities 49,431 49,317
Gross Unrealized Gains 12 18
Gross Unrealized Losses 0 0
Marketable securities, fair value $ 49,443 $ 49,335
v3.25.4
Other Financial Statement Information - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
May 31, 2025
Feb. 28, 2025
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenues from External Customers and Long-Lived Assets [Line Items]          
Debt securities, available-for-sale, realized loss     $ 0 $ 0 $ 1,700,000
Depreciation expense     31,200,000 33,900,000 32,900,000
Impairment of long lived assets     2,100,000 3,100,000 9,800,000
Gross Carrying Amount     77,416,000 25,777,000  
Remaining performance obligations for warranty service agreements     34,400,000    
Deferred revenue     23,902,000 20,658,000  
Contract liability     34,403,000 33,171,000 21,964,000
Gain on settlement     49,900,000 0 0
Total revenue     642,823,000 610,785,000 618,727,000
Foreign currency transaction gains (losses)     2,500,000 (2,100,000) 1,200,000
Change in fair value     1,407,000 0 0
Scale BioScience Inc. Acquisition          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Change in fair value     1,407,000    
Products And Services, Excluding Grant Revenue          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Deferred revenue     23,900,000    
License and royalty revenue          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Total revenue     46,135,000 321,000 0
Vizgen, Inc.          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Amount of litigation settlement and intellectual property license granted   $ 26,000,000      
Gain on settlement   9,200,000      
Vizgen, Inc. | License and royalty revenue          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Total revenue   $ 16,800,000      
Bruker Corporation          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Amount of litigation settlement and intellectual property license granted $ 68,000,000        
Gain on settlement 40,700,000        
Total revenue $ 27,300,000        
Developed technology          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Impairment of long lived assets     700,000 0 $ 4,600,000
Gross Carrying Amount     52,639,000 1,000,000  
Developed technology | Scale BioScience Inc. Acquisition          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Gross Carrying Amount     51,600,000    
Assembled workforce          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Gross Carrying Amount     1,328,000 1,328,000  
Assembled workforce | Scale BioScience Inc. Acquisition          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Gross Carrying Amount     700,000    
Computer equipment          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Impairment of long lived assets     $ 100,000 2,100,000  
Cost of revenue          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Impairment of long lived assets       300,000  
Research and development          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Impairment of long lived assets       700,000  
Selling, general and administrative          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Impairment of long lived assets       $ 1,100,000  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2026-01-01          
Revenues from External Customers and Long-Lived Assets [Line Items]          
Expected period of revenue recognition     12 months    
v3.25.4
Other Financial Statement Information - Schedule of Inventory (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Finished goods $ 23,183 $ 16,736
Work in progress 17,135 27,441
Purchased materials 16,023 38,930
Inventory $ 56,341 $ 83,107
v3.25.4
Other Financial Statement Information - Schedule of Property and Equipment (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 380,175 $ 375,615
Less: accumulated depreciation and amortization (153,464) (122,967)
Property and equipment, net 226,711 252,648
Building    
Property, Plant and Equipment [Line Items]    
Total property and equipment 147,493 147,094
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Total property and equipment 89,724 89,567
Laboratory equipment and machinery    
Property, Plant and Equipment [Line Items]    
Total property and equipment 78,133 72,498
Land    
Property, Plant and Equipment [Line Items]    
Total property and equipment 36,765 36,765
Computer equipment and software    
Property, Plant and Equipment [Line Items]    
Total property and equipment 15,281 14,953
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Total property and equipment 9,850 9,586
Construction in progress    
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 2,929 $ 5,152
v3.25.4
Other Financial Statement Information - Intangible Assets, Net (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 77,416 $ 25,777
Accumulated Amortization (15,087) (10,106)
Intangibles, Net $ 62,329 15,671
Developed technology    
Finite-Lived Intangible Assets [Line Items]    
Remaining Useful Life in Years 6 years  
Gross Carrying Amount $ 52,639 1,000
Accumulated Amortization (3,359) (92)
Intangibles, Net $ 49,280 908
Technology licenses    
Finite-Lived Intangible Assets [Line Items]    
Remaining Useful Life in Years 8 years 9 months 18 days  
Gross Carrying Amount $ 22,504 22,504
Accumulated Amortization (9,491) (8,016)
Intangibles, Net $ 13,013 14,488
Assembled workforce    
Finite-Lived Intangible Assets [Line Items]    
Remaining Useful Life in Years 6 months  
Gross Carrying Amount $ 1,328 1,328
Accumulated Amortization (1,292) (1,080)
Intangibles, Net $ 36 248
Customer relationships    
Finite-Lived Intangible Assets [Line Items]    
Remaining Useful Life in Years 0 years  
Gross Carrying Amount $ 945 945
Accumulated Amortization (945) (918)
Intangibles, Net $ 0 $ 27
v3.25.4
Other Financial Statement Information - Annual Amortization of Intangible Assets (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Estimated Annual Amortization    
2026 $ 9,644  
2027 9,609  
2028 9,609  
2029 9,608  
2030 9,569  
Thereafter 14,290  
Intangibles, Net $ 62,329 $ 15,671
v3.25.4
Other Financial Statement Information - Schedule of Accrued Compensation and Related Benefits (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Accrued bonus $ 29,506 $ 21,859
Accrued commissions 5,335 5,938
Accrued payroll and related costs 4,964 2,970
Other 2,695 2,848
Accrued compensation and related benefits $ 42,500 $ 33,615
v3.25.4
Other Financial Statement Information - Schedule of Accrued Expense and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Taxes payable $ 7,219 $ 4,936
Product warranties 6,828 8,615
Customer refunds and deposits payable 5,542 3,002
Accrued royalties for licensed technologies 4,971 7,042
Accrued professional services 2,914 5,315
Accrued legal and related costs 1,502 6,100
Accrued property and equipment 124 644
Other 10,871 5,511
Accrued expenses and other current liabilities $ 39,971 $ 41,165
v3.25.4
Other Financial Statement Information - Schedule of Changes in the Reserve for Product Warranties (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Movement in Standard and Extended Product Warranty Accrual, Increase (Decrease) [Roll Forward]    
Beginning of period $ 8,615 $ 8,116
Amounts charged to cost of revenue 8,567 13,325
Repairs and replacements (10,354) (12,826)
End of period $ 6,828 $ 8,615
v3.25.4
Other Financial Statement Information - Summary of the Change in Contract Liabilities (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Contract with Customer, Liability [Roll Forward]    
Contract liability, beginning balance $ 33,171 $ 21,964
Revenue recognized that was included in the contract liability at the beginning of the year (20,130) (11,407)
Revenue deferred excluding amounts recognized as revenue during the period 21,362 22,614
Contract liability, ending balance $ 34,403 $ 33,171
v3.25.4
Other Financial Statement Information - Schedule of Revenue by Source (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenue from External Customer [Line Items]      
Total revenue $ 642,823 $ 610,785 $ 618,727
Instruments      
Revenue from External Customer [Line Items]      
Total revenue 56,779 92,715 123,471
Single Cell      
Revenue from External Customer [Line Items]      
Total revenue 22,671 35,212 47,866
Spatial      
Revenue from External Customer [Line Items]      
Total revenue 34,108 57,503 75,605
Consumables      
Revenue from External Customer [Line Items]      
Total revenue 507,183 493,432 479,553
Single Cell      
Revenue from External Customer [Line Items]      
Total revenue 363,206 372,308 420,316
Spatial      
Revenue from External Customer [Line Items]      
Total revenue 143,977 121,124 59,237
Services      
Revenue from External Customer [Line Items]      
Total revenue 32,726 24,317 15,703
Products and services revenue      
Revenue from External Customer [Line Items]      
Total revenue 596,688 610,464 618,727
License and royalty revenue      
Revenue from External Customer [Line Items]      
Total revenue $ 46,135 $ 321 $ 0
v3.25.4
Other Financial Statement Information - Schedule of Revenue by Geographic Region (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue $ 642,823 $ 610,785 $ 618,727
Americas      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 358,773 347,765 373,192
United States      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 346,512 334,318 360,091
Americas (excluding United States)      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 12,261 13,447 13,101
Europe, Middle East and Africa      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 161,716 159,762 142,276
Asia-Pacific      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 122,334 103,258 103,259
China      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue 70,264 57,300 50,965
Asia-Pacific (excluding China)      
Revenues from External Customers and Long-Lived Assets [Line Items]      
Total revenue $ 52,070 $ 45,958 $ 52,294
v3.25.4
Income Tax - Schedule of Income (Loss) Before Provision for Income Taxes (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Income Tax Contingency [Line Items]      
Income (loss) before provision for income taxes $ (39,907) $ (177,700) $ (248,763)
United States      
Income Tax Contingency [Line Items]      
Income (loss) before provision for income taxes (44,598) (187,720) (263,292)
International      
Income Tax Contingency [Line Items]      
Income (loss) before provision for income taxes $ 4,691 $ 10,020 $ 14,529
v3.25.4
Income Tax - Provision for Income Taxes (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Current provision:      
Federal $ (7) $ 396 $ 351
State 397 314 180
Foreign 3,557 3,508 6,252
Total current provision for income taxes 3,947 4,218 6,783
Deferred provision:      
Federal 0 0 0
State 0 0 0
Foreign (310) 709 (447)
Total deferred provision for income taxes (310) 709 (447)
Total provision for income taxes $ 3,637 $ 4,927 $ 6,336
v3.25.4
Income Tax - Schedule of Reconciliation of the Federal Statutory Income Tax Rate (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Amount      
U.S. federal statutory tax rate $ (8,380)    
State and local income taxes, net of federal income tax effect (2,363)    
Other   $ 383 $ (199)
Effect of cross-border tax laws 336    
Research and development tax credits (4,250)    
Changes in valuation allowance (5,038)    
Stock-based compensation 14,551 15,978 2,422
Executive compensation (162(m)) 1,208    
Other items 503    
Changes in unrecognized tax benefits 5,865    
Total provision for income taxes $ 3,637 $ 4,927 $ 6,336
Percent      
U.S. federal statutory tax rate 21.00%    
State and local income taxes, net of federal income tax effect 6.00%    
Effect of cross-border tax laws (1.00%)    
Research and development tax credits 11.00%    
Changes in valuation allowance 13.00%    
Stock-based compensation (37.00%)    
Executive compensation (162(m)) (3.00%)    
Other items (1.00%)    
Changes in unrecognized tax benefits (15.00%)    
Effective tax rate (9.00%)    
Singapore      
Amount      
Nondeductible compensation $ 1,179    
Other $ (248)    
Percent      
Nondeductible compensation (3.00%)    
Other 1.00%    
Other foreign jurisdictions      
Amount      
Other foreign jurisdictions $ 274    
Percent      
Other foreign jurisdictions (1.00%)    
v3.25.4
Income Tax - Schedule of Reconciliation of the Federal Statutory Income Tax Provision (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]      
Income tax provision at federal statutory rate   $ (37,317) $ (52,240)
State taxes, net of federal benefit   (11,938) (14,831)
Tax credits   (8,895) (14,551)
Foreign taxes   2,148 3,888
Stock-based compensation $ 14,551 15,978 2,422
Change in valuation allowance   36,378 79,551
Acquisition related expenses   0 2,296
Waived deductions under Section 59A   8,190 0
Other   383 (199)
Total provision for income taxes $ 3,637 $ 4,927 $ 6,336
v3.25.4
Income Tax - Schedule of Major Components of Deferred Tax Assets and Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Deferred tax assets    
Net operating loss carryforwards $ 202,704 $ 161,681
Research and development tax credits 111,143 103,555
Accruals and reserves 17,323 12,302
Operating lease liability 19,441 19,628
Intangibles 27,845 35,966
Stock-based compensation 24,383 26,772
Capitalized research and development 103,001 136,267
Total deferred tax assets 505,840 496,171
Valuation allowance (490,154) (479,452)
Net deferred tax assets 15,686 16,719
Deferred tax liabilities    
Property and equipment (2,855) (4,124)
Operating right-of-use assets (13,436) (13,510)
Total deferred tax liabilities (16,291) (17,634)
Net deferred tax liabilities $ (605) $ (915)
v3.25.4
Income Tax - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Operating Loss Carryforwards [Line Items]      
Change in valuation allowance $ 10,700 $ 36,400  
Unrecognized gross tax benefits 55,490 50,022 $ 45,713
Unrecognized gross tax benefit that would affect effective tax rate if recognized 3,300 2,900  
Interest and penalties accrued 2,100 1,600  
Interest and penalties expense 600 $ 700 $ 500
Domestic Tax Jurisdiction      
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards 808,100    
Tax credit carryforward 93,800    
Domestic Tax Jurisdiction | Operating Loss Carryforwards, Indefinitely Carried Forward      
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards 802,300    
State and Local Jurisdiction      
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards 506,500    
Tax credit carryforward $ 77,400    
v3.25.4
Income Tax - Schedule of Income taxes paid (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Amount      
State $ 195    
Cash paid for taxes $ 2,391 $ 5,641 $ 4,927
Percent      
State 8.00%    
Total income taxes paid, net of refunds received 100.00%    
Singapore      
Amount      
Foreign $ 947    
Percent      
Foreign 40.00%    
Other foreign jurisdictions      
Amount      
Foreign $ 1,249    
Percent      
Foreign 52.00%    
v3.25.4
Income Tax - Schedule Of Unrecognized Gross Tax Benefits (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Unrecognized Tax Benefits [Roll Forward]    
Unrecognized tax benefits at beginning of year $ 50,022 $ 45,713
Reductions related to settlements with tax authorities 0 (285)
Reductions based on prior year tax provisions (739) (1,617)
Additions related to acquisitions 2,287 0
Additions based on prior year tax provisions 436 467
Additions based on current year tax provisions 3,484 5,744
Unrecognized tax benefits at end of year $ 55,490 $ 50,022
v3.25.4
Commitments and Contingencies - Additional Information (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Mar. 25, 2024
patentClaim
Oct. 31, 2025
lawsuit
Aug. 31, 2025
USD ($)
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Loss Contingencies [Line Items]            
Minimum purchase commitment       $ 12,200    
Minimum purchase commitment term       2 years    
Present value of operating lease liabilities       $ 84,361    
Operating lease right-of-use assets       60,450 $ 57,290  
Asset and lease impairment charges       814 3,054 $ 9,845
Operating lease cost       12,500 12,600 13,600
Variable lease cost       1,000 500 200
Sublease Income       600 1,200 500
Operating lease payments       $ 16,200 $ 17,800 $ 15,200
Positive Outcome of Litigation | Curio Patent Claims            
Loss Contingencies [Line Items]            
Number of patent claims | patentClaim 1          
Positive Outcome of Litigation | Illumina Lawsuits            
Loss Contingencies [Line Items]            
Number of lawsuits filed | lawsuit   2        
Scale BioScience Inc. Acquisition            
Loss Contingencies [Line Items]            
Present value of operating lease liabilities     $ 1,800      
Operating lease right-of-use assets     1,800      
Asset and lease impairment charges     $ 1,300      
Maximum            
Loss Contingencies [Line Items]            
Operating lease term       10 years    
Intellectual Property            
Loss Contingencies [Line Items]            
Contractual obligation       $ 24,900    
Contractual obligation term       16 years    
Software Development            
Loss Contingencies [Line Items]            
Contractual obligation       $ 18,600    
Contractual obligation term       4 years    
v3.25.4
Commitments and Contingencies - Schedule of Company's Operating Lease Liabilities (Details) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Commitments and Contingencies Disclosure [Abstract]    
2026 $ 15,630  
2027 16,805  
2028 16,394  
2029 14,800  
2030 9,853  
Thereafter 29,537  
Total lease payments 103,019  
Less: imputed interest (18,658)  
Present value of operating lease liabilities 84,361  
Operating lease liabilities, current 10,985 $ 9,286
Operating lease liabilities, noncurrent 73,376 $ 73,327
Total operating lease liabilities $ 84,361  
v3.25.4
Commitments and Contingencies - Schedule of Additional Information Related to Operating Leases (Details)
Dec. 31, 2025
Dec. 31, 2024
Commitments and Contingencies Disclosure [Abstract]    
Weighted-average remaining lease term, operating leases 6 years 8 months 12 days 6 years 9 months 18 days
Weighted-average discount rate, operating leases 5.90% 5.80%
v3.25.4
Capital Stock - Additional Information (Detail)
Dec. 31, 2025
vote
$ / shares
shares
Dec. 31, 2024
$ / shares
shares
Class of Stock [Line Items]    
Shares of capital stock authorized (in shares) 1,200,000,000  
Common stock authorized (in shares) 1,100,000,000 1,100,000,000
Preferred stock authorized (in shares) 100,000,000 100,000,000
Common stock par value (in dollars per share) | $ / shares $ 0.00001 $ 0.00001
Common Class A    
Class of Stock [Line Items]    
Common stock authorized (in shares) 1,000,000,000 1,000,000,000
Common stock par value (in dollars per share) | $ / shares $ 0.00001  
Number of votes per share | vote 1  
Common Class B    
Class of Stock [Line Items]    
Common stock authorized (in shares) 100,000,000 100,000,000
Common stock par value (in dollars per share) | $ / shares $ 0.00001  
Number of votes per share | vote 10  
Convertible Preferred Stock    
Class of Stock [Line Items]    
Preferred stock authorized (in shares) 100,000,000  
v3.25.4
Capital Stock - Schedule of Common Stock Issued and Outstanding (Details) - shares
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Class B common stock converted to Class A common stock      
Class of Stock [Line Items]      
Common stock shares converted (in shares) 3,977,961 0 4,610,422
v3.25.4
Equity Incentive Plans - Additional Information (Detail)
$ / shares in Units, $ in Millions
1 Months Ended 12 Months Ended
Mar. 31, 2025
shares
Mar. 31, 2024
shares
Mar. 31, 2023
shares
Sep. 30, 2022
shares
Dec. 31, 2025
USD ($)
day
$ / shares
shares
Dec. 31, 2024
USD ($)
$ / shares
shares
Dec. 31, 2023
USD ($)
$ / shares
shares
Performance Stock Awards, granted (in shares)         6,184,585    
Weighted-average grant date fair value, granted PSUs (in dollars per share) | $ / shares         $ 10.65    
Restricted Stock Units (RSUs)              
Unrecognized stock-based compensation | $         $ 118.0    
Weighted-average period of recognition for stock options         2 years    
Compound Annual Growth Rate              
PSA target percentage 50.00% 50.00%          
Performance period 2 years 2 years          
Total Shareholder Return              
PSA target percentage 50.00% 50.00%          
Performance period 3 years 3 years          
Minimum | Compound Annual Growth Rate              
PSA target amount of shares percentage 0.00% 0.00%          
Minimum | Total Shareholder Return              
PSA target amount of shares percentage 0.00% 0.00%          
Maximum | Compound Annual Growth Rate              
PSA target amount of shares percentage 200.00% 175.00%          
Maximum | Total Shareholder Return              
PSA target amount of shares percentage 200.00% 200.00%          
2019 Omnibus Incentive Plan              
Percentage increase in shares on stock outstanding         5.00%    
Contractual term         10 years    
Stock options grant date fair value (in dollars per share) | $ / shares             $ 33.67
Intrinsic value of stock options exercised | $         $ 4.4 $ 12.3 $ 78.0
Unrecognized stock-based compensation | $         $ 4.9    
Weighted-average period of recognition for stock options         1 year    
2019 Omnibus Incentive Plan | Minimum              
Exercise price percentage on fair market value         100.00%    
2019 Plan | Performance Stock Units              
Performance Stock Awards, granted (in shares) 561,603 219,168          
2019 Plan | Performance Stock Options and Restricted Stock Units              
Performance Stock Awards, granted (in shares)     172,842 709,025      
Market-based Performance Awards              
Weighted-average grant date fair value, granted PSUs (in dollars per share) | $ / shares         $ 0 $ 0  
Employee benefits and share-based compensation | $         $ 1.3 $ 1.3  
Market-based Performance Awards | Compound Annual Growth Rate              
Weighted-average grant date fair value, granted PSUs (in dollars per share) | $ / shares         $ 10.76 $ 37.43  
Market-based Performance Awards | Total Shareholder Return              
Weighted-average grant date fair value, granted PSUs (in dollars per share) | $ / shares         $ 13.94 $ 44.80  
Employee benefits and share-based compensation | $         $ 1.0    
March 2023 Market-based Performance Awards              
Weighted-average grant date fair value, granted PSUs (in dollars per share) | $ / shares         $ 43.13    
Employee benefits and share-based compensation | $           $ 1.7 5.1
Threshold consecutive day | day         20    
March 2023 Market-based Performance Awards | Tranche One              
Proceeds from issuance of stock (in dollars per share) | $ / shares         $ 72.14    
March 2023 Market-based Performance Awards | Tranche Two              
Proceeds from issuance of stock (in dollars per share) | $ / shares         96.19    
March 2023 Market-based Performance Awards | Tranche Three              
Proceeds from issuance of stock (in dollars per share) | $ / shares         $ 120.24    
September 2022 Market-based Performance Awards              
Employee benefits and share-based compensation | $           $ 2.4 $ 10.0
2019 Employee Stock Purchase Plan              
Percentage increase in shares on stock outstanding         1.00%    
Stock options grant date fair value (in dollars per share) | $ / shares         $ 4.07 $ 6.42 $ 16.91
Unrecognized stock-based compensation | $         $ 1.0    
Weighted-average period of recognition for stock options         4 months 24 days    
Employee contribution percentage         15.00%    
Offering period         6 months    
2019 Employee Stock Purchase Plan | Employee Stock              
Common stock reserved for issuance (in shares)         3,223,673    
Common Class A | 10x Genomics, Inc. 2012 Stock Plan              
Common stock issuable upon the exercise of stock options (in shares)         1,295,245    
Common Class A | 2019 Omnibus Incentive Plan              
Common stock issuable upon the exercise of stock options (in shares)         21,857,245    
Shares issuable in connection with outstanding awards (in shares)         10,092,793    
Common stock reserved for issuance (in shares)         11,000,000    
Share-based payment award, number of shares authorized (in shares)         11,000,000    
Common Class A | 2019 Employee Stock Purchase Plan              
Common stock reserved for issuance (in shares)         4,909,589    
Common Class A | 2019 Employee Stock Purchase Plan | Employee Stock              
Shares issued in period for previously outstanding awards (in shares)         708,628 385,967 217,537
v3.25.4
Equity Incentive Plans - Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions (Detail) - 2019 Omnibus Incentive Plan - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Outstanding Options    
Outstanding options, Beginning balance (in shares) 4,594,582  
Outstanding Options, Exercised (in shares) (478,085)  
Cancelled and forfeited (in shares) (555,200)  
Outstanding options, Ending balance (in shares) 3,561,297 4,594,582
Weighted- Average Exercise Price    
Weighted-Average Exercise Price, Beginning balance (in dollars per share) $ 45.37  
Weighted-Average Exercise Price, Exercised (in dollars per share) 2.83  
Weighted-Average Exercise Price, Cancelled and forfeited (in dollars per share) 61.62  
Weighted-Average Exercise Price, Ending balance (in dollars per share) $ 48.55 $ 45.37
Options Outstanding, Weighted-Average Remaining Term (Years) 4 years 7 months 6 days 5 years 4 months 24 days
Options Outstanding, Aggregate Intrinsic Value $ 10,337,526 $ 13,834,082
Weighted-Average Remaining Terms and Aggregate Intrinsic Value    
Outstanding Options, Vested and exercisable (in shares) 3,253,508  
Weighted-Average Exercise Price, Vested and exercisable (in dollars per share) $ 49.02  
Options Outstanding, Weighted-Average Remaining Term, Vested and exercisable 4 years 4 months 24 days  
Options Outstanding, Aggregate Intrinsic Value, Vested and exercisable $ 10,337,526  
v3.25.4
Equity Incentive Plans - Schedule of Stock Option Valuation Assumptions (Detail)
12 Months Ended
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Expected dividend 0.00%
Minimum  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Expected volatility 70.00%
Risk-free interest rate 3.70%
Expected term (in years) 5 years 3 months 18 days
Maximum  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Expected volatility 71.00%
Risk-free interest rate 4.60%
Expected term (in years) 6 years 1 month 6 days
v3.25.4
Equity Incentive Plans - Schedule of RSU Activity (Detail)
12 Months Ended
Dec. 31, 2025
$ / shares
shares
Restricted Stock Units  
Restricted Stock Units, Beginning balance (in shares) | shares 6,493,387
Restricted Stock Units, Granted (in shares) | shares 6,184,585
Restricted Stock Units, Vested (in shares) | shares (3,117,074)
Restricted Stock Units, Forfeited (in shares) | shares (1,734,157)
Restricted Stock Units, Ending balance (in shares) | shares 7,826,741
Weighted-Average Grant Date Fair Value (per share)  
Weighted-Average Grant Date Fair Value, Beginning balance (in dollars per share) | $ / shares $ 35.55
Weighted-Average Grant Date Fair Value, Granted (in dollars per share) | $ / shares 10.65
Weighted-Average Grant Date Fair Value, Vested (in dollars per share) | $ / shares 30.68
Weighted-Average Grant Date Fair Value, Forfeited (in dollars per share) | $ / shares 27.12
Weighted-Average Grant Date Fair Value, Ending balance (in dollars per share) | $ / shares $ 19.68
v3.25.4
Equity Incentive Plans - Fair Values of Shares Under the Performance Stock Options (Details)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected dividend     0.00%
Performance Stock Units      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected volatility 67.00% 66.00%  
Risk-free interest rate 4.00% 4.50%  
Expected dividend 0.00% 0.00%  
v3.25.4
Equity Incentive Plans - Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions (Details)
12 Months Ended
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Expected dividend 0.00%
Performance Stock Awards  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Expected volatility 71.00%
Risk-free interest rate 3.70%
Expected dividend 0.00%
v3.25.4
Equity Incentive Plans - Schedule of Fair value of the Employee Stock Purchase Plan (Details)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected dividend     0.00%
Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected volatility     70.00%
Risk-free interest rate     3.70%
Expected term (in years)     5 years 3 months 18 days
Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected volatility     71.00%
Risk-free interest rate     4.60%
Expected term (in years)     6 years 1 month 6 days
2019 Employee Stock Purchase Plan      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term (in years) 6 months    
Expected dividend 0.00% 0.00% 0.00%
2019 Employee Stock Purchase Plan | Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected volatility 67.00% 49.00% 49.00%
Risk-free interest rate 3.80% 4.44% 5.24%
Expected term (in years)   6 months 6 months
2019 Employee Stock Purchase Plan | Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected volatility 75.00% 80.00% 58.00%
Risk-free interest rate 4.30% 5.40% 5.41%
v3.25.4
Equity Incentive Plans - Schedule of Recorded Stock-Based Compensation Expense in the Condensed Consolidated Statement of Operations (Details)) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Share-based Payment Arrangement, Expensed [Line Items]      
Stock-based compensation expense $ 108,804 $ 140,749 $ 166,950
Cost of revenue      
Share-based Payment Arrangement, Expensed [Line Items]      
Stock-based compensation expense 8,497 8,348 7,068
Research and development      
Share-based Payment Arrangement, Expensed [Line Items]      
Stock-based compensation expense 49,568 66,315 72,804
Selling, general and administrative      
Share-based Payment Arrangement, Expensed [Line Items]      
Stock-based compensation expense $ 50,739 $ 66,086 $ 87,078
v3.25.4
Employee Benefit Plans (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Defined Benefit Plan Disclosure [Line Items]      
Defined contribution plan, employers matching contribution, percentage 100.00%    
Defined contribution plan, employer matching contribution, first percentage 3.00%    
Defined benefit plan, plan assets, contributions by employer $ 1,900 $ 1,900 $ 1,800
Maximum      
Defined Benefit Plan Disclosure [Line Items]      
Defined benefit plan, plan assets, contributions by employer $ 2    
v3.25.4
Net Loss Per Share (Detail) - shares
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 11,447,558 11,212,621 11,329,222
Restricted stock units      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 7,826,741 6,493,387 5,334,134
Stock options to purchase common stock      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 3,561,297 4,594,582 5,946,786
Shares committed under ESPP      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 59,520 124,652 48,302