AVENUE THERAPEUTICS, INC., 10-Q filed on 5/12/2017
Quarterly Report
Document And Entity Information
3 Months Ended
Mar. 31, 2017
May 4, 2017
Document Information [Line Items]
 
 
Document Type
10-Q 
 
Amendment Flag
false 
 
Document Period End Date
Mar. 31, 2017 
 
Document Fiscal Year Focus
2017 
 
Document Fiscal Period Focus
Q1 
 
Entity Registrant Name
AVENUE THERAPEUTICS, INC. 
 
Entity Central Index Key
0001644963 
 
Current Fiscal Year End Date
--12-31 
 
Entity Filer Category
Non-accelerated Filer 
 
Trading Symbol
ATXI 
 
Entity Common Stock, Shares Outstanding
 
10,024,405 
CONDENSED BALANCE SHEETS (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2017
Dec. 31, 2016
Current Assets:
 
 
Cash
$ 0 
$ 197 
Deferred financing costs
234 
Total Assets
234 
197 
Current Liabilities:
 
 
Accounts payable and accrued expenses
868 
506 
Accrued expenses - related party
1,568 
1,348 
Interest payable
57 
Accrued interest - related party
404 
346 
Notes payable - related party
2,919 
2,848 
NSC notes payable, short-term
1,750 
1,000 
Derivative warrant liability
311 
314 
Total current liabilities
7,825 
6,419 
Convertible notes payable, at fair value
204 
200 
NSC notes payable, long-term (net of debt discount of $141 and $174, respectively)
1,109 
1,826 
Total Liabilities
9,138 
8,445 
Commitments and Contingencies (Note 7)
   
   
Stockholders' Deficit
 
 
Common shares; 10,024,405 and 9,773,810 shares issued and outstanding as of March 31, 2017 and December 31, 2016, respectively
Common stock issuable, 0 and 250,595 shares as of March 31, 2017 and December 31, 2016, respectively
49 
Additional paid-in capital
159 
105 
Accumulated deficit
(9,064)
(8,403)
Total Stockholders' Deficit
(8,904)
(8,248)
Total Liabilities and Stockholders' Deficit
234 
197 
Series A Preferred Stock [Member]
 
 
Stockholders' Deficit
 
 
Preferred Stock, Value, Issued
$ 0 
$ 0 
CONDENSED BALANCE SHEETS (Parenthetical) (USD $)
In Thousands, except Share data, unless otherwise specified
Mar. 31, 2017
Dec. 31, 2016
Preferred Stock, Par or Stated Value Per Share
$ 0.0001 
$ 0.0001 
Preferred Stock, Shares Authorized
2,000,000 
2,000,000 
Common Stock, Par or Stated Value Per Share
$ 0.0001 
$ 0.0001 
Common Stock, Shares Authorized
50,000,000 
50,000,000 
Common Stock, Shares, Issued
10,024,405 
9,773,810 
Common Stock, Shares, Outstanding
10,024,405 
9,773,810 
Common Stock Shares issuable
250,595 
Series A Preferred Stock [Member]
 
 
Preferred Stock, Shares Issued
250,000 
250,000 
Preferred Stock, Shares Outstanding
250,000 
250,000 
NSC Notes Memebers [Member]
 
 
Debt Instrument, Unamortized Discount
$ 141 
$ 174 
CONDENSED STATEMENT OF OPERATIONS (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Operating expenses:
 
 
Research and development
$ 133 
$ 564 
General and administration
371 
276 
Loss from operations
(504)
(840)
Interest expense
95 
85 
Interest expense - related party
61 
33 
Change in fair value of convertible notes payable
89 
Change in fair value of warrant liabilities
(3)
Net Loss
$ (661)
$ (1,047)
Net loss per common share outstanding, basic and diluted
$ (0.07)
$ (0.13)
Weighted average number of common shares outstanding, basic and diluted
9,068,539 
8,310,604 
CONDENSED STATEMENT OF STOCKHOLDERS' EQUITY (USD $)
Total
Common Stock [Member]
Preferred Stock [Member]
Common Stock issuable [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Balance at Dec. 31, 2016
$ (8,248,000)
$ 1,000 
$ 0 
$ 49,000 
$ 105,000 
$ (8,403,000)
Balance (Shares) at Dec. 31, 2016
 
9,773,810 
250,000 
 
 
 
Share based compensation
5,000 
5,000 
Issuance of common shares - Founders Agreement
(49,000)
49,000 
Issuance of common shares - Founders Agreement (in shares)
 
250,595 
 
 
 
Net loss
(661,000)
(661,000)
Balance at Mar. 31, 2017
$ (8,904,000)
$ 1,000 
$ 0 
$ 0 
$ 159,000 
$ (9,064,000)
Balance (Shares) at Mar. 31, 2017
 
10,024,405 
250,000 
 
 
 
CONDENSED STATEMENT OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Cash flows from operating activities:
 
 
Net loss
$ (661)
$ (1,047)
Adjustments to reconcile net loss to net cash used in operating activities:
 
 
Share based compensation
Change in fair value of convertible notes payable
89 
Change in fair value of warrant liabilities
(3)
Debt discount amortization
33 
29 
Changes in operating assets and liabilities:
 
 
Accounts payable and accrued expenses
362 
(192)
Accrued expenses - related party
220 
206 
Interest payable
(52)
Accrued interest - related party
58 
29 
Net cash used in operating activities
(34)
(877)
Cash flows from financing activities:
 
 
Deferred financing costs
(234)
Proceeds from notes payable - related party
71 
875 
Net cash (used in) provided by financing activities
(163)
875 
Net change in cash
(197)
(2)
Cash, beginning of period
197 
14 
Cash, end of period
12 
Supplemental disclosure of cash flow information:
 
 
Cash paid for interest
$ 115 
$ 85 
Organization, Plan of Business Operations and Going Concern Consideration
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Note 1 - Organization, Plan of Business Operations and Going Concern Consideration
 
Avenue Therapeutics, Inc. (the “Company” or “Avenue”) was incorporated in Delaware on February 9, 2015, as a wholly owned subsidiary of Fortress Biotech, Inc. (“Fortress”), to develop and market pharmaceutical products for the acute care setting in the United States. The company will focus on developing its product candidate, an intravenous (“IV”) formulation of tramadol HCI (“IV Tramadol”), for moderate to moderately severe post-operative pain.
  
Going Concern Consideration
 
As of March 31, 2017, the Company’s working capital deficit was approximately $7.6 million and the Company’s stockholders' deficit was $8.9 million. To date the Company has funded operations through our $3.0 million note in favor of NSC Biotech Venture Fund I, LLC (“NSC Note”) and a working capital line of credit from Fortress (“Fortress Note”). As of March 31, 2017, the Company has borrowed $2.9 million under this credit facility.
 
The accompanying financial statements have been prepared on a going concern basis, which contemplates the realization of assets and satisfaction of liabilities in the normal course of business. The financial statements do not include any adjustments relating to the recoverability and classification of recorded asset amounts or the amounts and classification of liabilities that might result from the outcome of this uncertainty. The Company anticipates incurring additional losses until such time, if ever, that it can obtain marketing approval to sell, and then generate significant sales, of its drug candidate that is currently in development. Substantial additional financing will be needed by the Company to fund its operations and to develop and commercialize its drug candidate. These factors raise substantial doubt about the Company’s ability to continue as a going concern.
 
The Company will seek to obtain additional capital through the sale of debt or equity financings or other arrangements to fund operations; however, there can be no assurance that the Company will be able to raise needed capital under acceptable terms, if at all. The sale of additional equity may dilute existing stockholders and newly issued shares may contain senior rights and preferences compared to currently outstanding shares of common stock. Issued debt securities may contain covenants and limit the Company’s ability to pay dividends or make other distributions to stockholders. If the Company is unable to obtain such additional financing, future operations would need to be scaled back or discontinued, until such time that capital is raised.
Significant Accounting Policies
Significant Accounting Policies [Text Block]
Note 2 - Significant Accounting Policies
 
Basis of Presentation
 
The accompanying unaudited interim condensed financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. In the opinion of management, the unaudited interim condensed financial statements reflect all adjustments, which include only normal recurring adjustments necessary for the fair statement of the balances and results for the periods presented. Certain information and footnote disclosures normally included in the Company’s annual financial statements prepared in accordance with GAAP have been condensed or omitted. These condensed financial statement results are not necessarily indicative of results to be expected for the full fiscal year or any future period.
 
Therefore, these condensed financial statements should be read in conjunction with the Company's audited financial statements and notes thereto for the year ended December 31, 2016, which were included in the Company’s Form 10-12 G/A, as amended, and filed with the U.S. Securities and Exchange Commission (“SEC”) on March 27, 2017. The results of operations for any interim periods are not necessarily indicative of the results that may be expected for the entire fiscal year or any other interim period.
 
The condensed financial statements may not be indicative of future performance and may not reflect what the results of operations, financial position, and cash flows would have been had Avenue operated as an independent entity. Certain estimates, including allocations from Fortress, have been made to provide financial statements for stand-alone reporting purposes. All inter-company transactions between Fortress and Avenue are classified as accrued expenses - related party in the financial statements. The Company believes that the assumptions underlying the financial statements are reasonable. The cost allocation methods applied to certain common costs include the following:
 
 
·
Specific identification.  Where the amounts were specifically identified to Avenue, they were classified accordingly.
 
·
Reasonable allocation.  Where the amounts were not clearly or specifically identified, management determined if a reasonable allocation method could be applied.  
 
Use of Estimates
 
The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.
 
Cash and Cash Equivalents
 
The Company considers all short-term investments with an original maturity of three months or less when purchased to be cash equivalents. There were no cash equivalents at March 31, 2017 and December 31, 2016. 
 
Research and Development
 
Research and development costs are expensed as incurred. Advance payments for goods and services that will be used in future research and development activities are expensed when the activity has been performed or when the goods have been received rather than when the payment is made. Upfront and milestone payments due to third parties that perform research and development services on the Company’s behalf will be expensed as services are rendered or when the milestone is probable. Costs incurred in obtaining technology licenses are charged to research and development expense if the technology licensed has not reached technological feasibility and has no alternative future use.
 
Research and development costs primarily consist of personnel related expenses, including salaries, benefits, travel, and other related expenses, stock-based compensation, payments made to third parties for license and milestone costs related to in-licensed products and technology, payments made to third party contract research organizations for preclinical and clinical studies, investigative sites for clinical trials, consultants, the cost of acquiring and manufacturing clinical trial materials, costs associated with regulatory filings and patents, laboratory costs and other supplies.
 
Costs incurred in obtaining technology licenses are charged to research and development expense if the technology licensed has not reached commercial feasibility and has no alternative future use. The licenses purchased by the Company require substantial completion of research and development, regulatory and marketing approval efforts in order to reach commercial feasibility and has no alternative future use. Accordingly, the total purchase price for the licenses acquired are reflected as research and development - licenses acquired on the Company’s Condensed Statement of Operations.
 
Annual Stock Dividend
 
In July 2016, in connection with the Amended and Restated Articles of Incorporation, the Company issued 250,000 Class A preferred shares to Fortress. The Class A preferred shares entitle the holder to a stock dividend equal to 2.5% of the fully diluted outstanding equity of the Company.
 
At December 31, 2016, the Company recorded the Annual Stock Dividend due to Fortress as contingent consideration. Contingent consideration is recorded when probable and reasonably estimable. The Company’s future share prices cannot be estimated due to the nature of its assets and the Company’s stage of development. Due to these uncertainties, the Company concluded that it could not reasonably estimate the contingent consideration until shares were actually issued on February 17, 2017. Because the issuance of shares on February 17, 2017 occurred prior to the issuance of the December 31, 2016 financial statements, the Company recorded approximately $49,000 in research and development - licenses acquired for the year ended December 31, 2016. On March 13, 2017, the Company issued the 250,595 common shares to Fortress and recorded an approximately $49,000 decrease in common shares issuable and a corresponding increase in additional paid in capital to account for the issuance of the PIK dividend.
 
Fair Value Measurement
 
The Company follows accounting guidance on fair value measurements for financial assets and liabilities measured at fair value on a recurring basis. Under the accounting guidance, fair value is defined as an exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. As such, fair value is a market-based measurement that should be determined based on assumptions that market participants would use in pricing an asset or a liability.
 
The accounting guidance requires fair value measurements be classified and disclosed in one of the following three categories:
 
Level 1: Quoted prices in active markets for identical assets or liabilities.
 
Level 2: Observable inputs other than Level 1 prices, for similar assets or liabilities that are directly or indirectly observable in the marketplace.
 
Level 3: Unobservable inputs which are supported by little or no market activity and that are financial instruments whose values are determined using pricing models, discounted cash flow methodologies, or similar techniques, as well as instruments for which the determination of fair value requires significant judgment or estimation.
 
The fair value hierarchy also requires an entity to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. Assets and liabilities measured at fair value are classified in their entirety based on the lowest level of input that is significant to the fair value measurement. The Company’s assessment of the significance of a particular input to the fair value measurement in its entirety requires management to make judgments and consider factors specific to the asset or liability.
    
Stock-Based Compensation
 
The Company expenses stock-based compensation to employees over the requisite service period based on the estimated grant-date fair value of the awards. For stock-based compensation awards to non-employees, the Company measures the fair value of the non-employee awards at each reporting period prior to vesting and finally at the vesting date of the award. Changes in the estimated fair value of these non-employee awards are recognized as compensation expense in the period of change.
 
The assumptions used in calculating the fair value of stock-based awards represent management’s best estimates and involve inherent uncertainties and the application of management’s judgment.
 
Valuation of Warrant Related to NSC Note
 
In accordance with ASC 815 Derivatives and Hedging, the Company classified the fair value of the warrant (“Contingently Issuable Warrants”) that it may be obligated to issue to NSC Biotech Venture Fund I, LLC (“NSC”), in connection with the transfer on October 31, 2015 of $3.0 million of indebtedness to NSC, as a derivative liability as there was a potential that the Company would not have a sufficient number of authorized common shares available to settle this instrument. The Company valued these Contingently Issuable Warrants using a Black-Scholes model and used estimates for an expected dividend yield, a risk-free interest rate, and expected volatility together with management’s estimate of the probability of issuance of the Contingently Issuable Warrants. At each reporting period, as long as the Contingently Issuable Warrants were potentially issuable and there was a potential for an insufficient number of authorized shares available to settle the Contingently Issuable Warrants, the Contingently Issuable Warrants should be revalued and any difference from the previous valuation date would be recognized as a change in fair value in the Company’s statement of operations.
 
Income Taxes
 
For purposes of these financial statements, the Company’s income tax expense and deferred tax balances have been recorded as if it filed tax returns on a stand-alone basis separate from Fortress.
 
Deferred tax assets and liabilities are determined based on the difference between the financial statement and tax bases of assets and liabilities measured at the enacted tax rates in effect for the year in which these items are expected to reverse. Deferred tax assets are reduced by valuation allowances if, based on the consideration of all available evidence, it is more likely than not that some portion or all of the deferred tax asset will not be realized.
 
Net loss per Share
 
Loss per share is computed by dividing net loss by the weighted-average number of common shares outstanding, excluding unvested restricted stock, during the period. Since dividends are declared paid and set aside among the holders of shares of common stock and Class A common stock pro-rata on an as-if-converted basis, the two-class method of computing net loss per share is not required. In the calculation of diluted loss per share, since there was no option or warrants as well as the conversion of rights, the diluted loss per share equaled the basic loss per share during the period.
 
Recently Adopted Accounting Standards
  
In August 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standard Update (“ASU”) 2014-15, Presentation of Financial Statements - Going Concern (Topic 915): Disclosure of Uncertainties about an Entity's Ability to Continue as a Going Concern (“ASU 2014-15”). ASU 2014-15 states that in connection with preparing financial statements for each annual and interim reporting period, an entity's management should evaluate whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the entity's ability to continue as a going concern within one year after the date that the financial statements are issued (or within one year after the date that the financial statements are available to be issued when applicable). ASU 2014-15 will be effective for annual and interim periods beginning on or after December 15, 2016. The Company adopted ASU No. 2014-15 2016, and its adoption did not have a material impact on the Company’s condensed financial statements.
 
In March 2016, the FASB issued ASU No. 2016-09 Compensation-Stock Compensation (Topic 718), Improvements to Employee Share-Based Payment Accounting (“ASU 2016-09”). Under ASU 2016-09, companies will no longer record excess tax benefits and certain tax deficiencies in additional paid-in capital (“APIC”). Instead, they will record all excess tax benefits and tax deficiencies as income tax expense or benefit in the income statement and the APIC pools will be eliminated. In addition, ASU 2016-09 eliminates the requirement that excess tax benefits be realized before companies can recognize them. ASU 2016-09 also requires companies to present excess tax benefits as an operating activity on the statement of cash flows rather than as a financing activity. Furthermore, ASU 2016-09 will increase the amount an employer can withhold to cover income taxes on awards and still qualify for the exception to liability classification for shares used to satisfy the employer’s statutory income tax withholding obligation. An employer with a statutory income tax withholding obligation will now be allowed to withhold shares with a fair value up to the amount of taxes owed using the maximum statutory tax rate in the employee’s applicable jurisdiction(s). ASU 2016-09 requires a company to classify the cash paid to a tax authority when shares are withheld to satisfy its statutory income tax withholding obligation as a financing activity on the statement of cash flows. Under current GAAP, it was not specified how these cash flows should be classified. In addition, companies will now have to elect whether to account for forfeitures on share-based payments by (1) recognizing forfeitures of awards as they occur or (2) estimating the number of awards expected to be forfeited and adjusting the estimate when it is likely to change, as is currently required. The Amendments of this ASU are effective for reporting periods beginning after December 15, 2016, with early adoption permitted but all of the guidance must be adopted in the same period. The Company adopted ASU 2016-09 in the first quarter of 2017, and its adoption did not have a material impact on the Company’s condensed financial statements. 
Allocation
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
Note 3 - Allocation
 
The expense allocations to Avenue, represents Lucy Lu's executive compensation, have been paid by Fortress and allocated by the Company between Avenue and Fortress based on time spent on Avenue projects versus time spent on Fortress projects. The allocations were based on assumptions that management believes are reasonable; however, these allocations are not necessarily indicative of the costs and expenses that would have resulted if Avenue had been operating as a stand-alone entity. For the three months ended March 31, 2017 and 2016, the allocated expenses related to Lucy Lu were approximately $95,000 and $81,000, respectively, and were recorded 50% to research and development and 50% to general and administration expenses.
Consulting Agreement
Consulting Agreement Disclosure [Text Block]
Note 4 - Consulting Agreement
 
On March 10, 2015, the Company entered into a consulting agreement with the CEO of Revogenex (the "Consultant") to provide consulting services to the Company. Under the terms of the agreement the Company paid $25,000 per calendar quarter to the Consultant throughout the initial one-year term of the agreement. On January 19, 2016, the Company terminated its agreement with the Consultant, effective March 10, 2016. For the three months ended March 31, 2017 and 2016, the Company had expenses related to the Consultant of approximately $0 and $16,667, respectively.
Related Party Agreements
Related Party Transactions Disclosure [Text Block]
Note 5 - Related Party Agreements
 
Founders Agreement and Management Services Agreement with Fortress
 
Fortress entered into a Founders Agreement with Avenue in February 2015, pursuant to which Fortress assigned to Avenue all of its rights and interest under Fortress’s license agreement with Revogenex for IV Tramadol (the “License Agreement”). As consideration for the Founders Agreement, Avenue assumed $3.0 million in debt that Fortress accumulated to NSC for expenses and costs of forming Avenue and obtaining the IV Tramadol license, of which $3.0 million represents the acquisition of the License Agreement. As additional consideration for the transfer of rights under the Founders Agreement, Avenue shall also: (i) issue annually to Fortress, on the anniversary date of the Founders Agreement, shares of common stock equal to two and one half percent (2.5%) of the fully-diluted outstanding equity of Avenue at the time of issuance; (ii) pay an equity fee in shares of Avenue common stock, payable within five (5) business days of the closing of any equity or debt financing for Avenue or any of its respective subsidiaries that occurs after the effective date of the Founders Agreement and ending on the date when Fortress no longer has majority voting control in Avenue’s voting equity, equal to two and one half percent (2.5%) of the gross amount of any such equity or debt financing; and (iii) pay a cash fee equal to four and one half percent (4.5%) of Avenue’s annual net sales, payable on an annual basis, within ninety (90) days of the end of each calendar year. In the event of a change in control (as it is defined in the Founders Agreement), Fortress will be paid a one-time change in control fee equal to five (5x) times the product of (i) net sales for the twelve (12) months immediately preceding the change in control and (ii) four and one-half percent (4.5%). 
 
On September 13, 2016, the Company entered into an Amended and Restated the Founders Agreement (“A&R Founders Agreement”) with Fortress. The A&R Founders Agreement eliminated the Annual Equity Fee in connection with the original agreement and added a term of 15 years, which upon expiration automatically renews for successive one-year periods unless terminated by Fortress or a Change in Control occurs. Concurrently with the A&R Founders Agreement the Company entered into an Exchange Agreement whereby the Company exchanged Fortress’ 7.0 million Class A common shares for approximately 7.4 million common shares and 250,000 Class A Preferred shares (see Note 8).
 
Effective as of February 17, 2015, Fortress entered into a Management Services Agreement (the “MSA”) with Avenue and each of Avenue’s current directors and officers who are directors or officers of Fortress, excluding services provided by Dr. Lucy Lu our Interim Chief Executive Officer and  Chief Financial Officer of Fortress, to provide services to Avenue pursuant to the terms of the MSA. Pursuant to the terms of the MSA, for a period of five (5) years, Fortress will render advisory and consulting services to Avenue. Services provided under the MSA may include, without limitation, (i) advice and assistance concerning any and all aspects of Avenue’s operations, clinical trials, financial planning and strategic transactions and financings and (ii) conducting relations on behalf of Avenue with accountants, attorneys, financial advisors and other professionals (collectively, the “Services”). Avenue is obligated to utilize clinical research services, medical education, communication and marketing services and investor relations/public relation services of companies or individuals designated by Fortress, provided those services are offered at market prices. However, Avenue is not obligated to take or act upon any advice rendered from Fortress and Fortress shall not be liable for any of Avenue’s actions or inactions based upon their advice. Fortress and its affiliates, including all members of Avenue’s Board of Directors, have been contractually exempt from fiduciary duties to Avenue relating to corporate opportunities. In consideration for the Services, Avenue will pay Fortress an annual consulting fee of $0.5 million (the “Annual Consulting Fee”), payable in advance in equal quarterly installments on the first business day of each calendar quarter in each year, provided, however, that such Annual Consulting Fee shall be increased to $1.0 million for each calendar year in which Avenue has net assets in excess of $100 million at the beginning of the calendar year.
  
For the three months ended March 31, 2017 and 2016, the Company had expenses related to the Management Services Agreement of approximately $125,000 and $125,000, respectively.
 
Fortress Note
 
Effective March 15, 2015, the Company and Fortress entered into a future advance promissory note (the “Fortress Note”), in which Fortress agreed to provide a working capital line of credit until the Company has a third-party financing. Interest on the Fortress Note is being accrued at 8% per annum and shall be payable to Fortress on the day after the end of each calendar quarter following the first third-party financing. All principal and accrued interest under the Fortress Note is payable on demand following the first third-party financing. This Fortress Note can be pre-paid at any time in cash or through the assumption of Fortress’ indebtedness NSC or other similar indebtedness.
 
As of March 31, 2017, the Fortress Note totaled approximately $2.9 million. For the three months ended March 31, 2017 and 2016, the Company had interest expense related to the Fortress Note of approximately $57,000 and $29,000, respectively.
 
Consulting Agreement with Chord Advisors, LLC (“Chord”)
 
On June 12, 2015, the Company entered into a full-service consulting agreement with Chord to provide advisory accounting services to the Company. Under the terms of the agreement, the Company will pay Chord five thousand dollars ($5,000) per month prior to becoming a public company and seven thousand five hundred dollars ($7,500) per month thereafter to perform back office accounting functions, accounting analysis and financial reporting. Either party upon 30-days written notice can terminate the agreement. In addition to these services, Mr. Horin, a Managing Partner of Chord, will serve as the Company’s Interim Chief Financial Officer. Chord also provides advisory accounting services to Fortress under a separate agreement.
 
For the three months ended March 31, 2017 and 2016, the Company had expenses related to the consulting agreement with Chord of approximately $15,000 and $20,000, respectively.
 
NSC Note and Financings
 
In September 2016, Fortress acquired through a tender offer 56.6% of National Holdings, Inc. (“National” or “NHLD”). The Company holds a $3.0 million NSC Note for which National Securities, Inc. (“NSC”), a subsidiary of National, received a 10% placement fee upon issuance of the Note to Fortress.
Notes Payable
Debt Disclosure [Text Block]
Note 6 - Notes Payable
 
NSC Note
 
At March 31, 2017, the Company has outstanding $3.0 million, under its NSC Note. The NSC Note bears interest at 8.0% per annum payable quarterly during the first twenty-four months (or the first thirty months, if the maturity date is extended) and monthly thereafter until maturity. In January 2017,  the Company extended the maturity date of the NSC Note to September 2018. The Company will commence to repay principal in September 2 017.
 
The following table summarizes NSC Note activities for the three months ended March 31, 2017:
 
($ in thousands)
 
Note Payable
 
Discount
 
Note Payable, Net
 
December 31, 2016 balance
 
$
3,000
 
$
(174)
 
$
2,826
 
Amortization of debt discount
 
 
-
 
 
33
 
 
33
 
March 31, 2017 balance
 
 
3,000
 
 
(141)
 
 
2,859
 
Less: NSC notes payable, short term
 
 
(1,750)
 
 
-
 
 
(1,750)
 
NSC notes payable, long term
 
$
1,250
 
$
(141)
 
$
1,109
 
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Note 7 - Commitments and Contingencies
 
Leases
 
The Company is not a party to any leases for office space or equipment.
 
Litigation
 
The Company recognizes a liability for a contingency when it is probable that liability has been incurred and when the amount of loss can be reasonably estimated. When a range of probable loss can be estimated, the Company accrues the most likely amount of such loss, and if such amount is not determinable, then the Company accrues the minimum of the range of probable loss. As of March 31, 2017, there was no litigation against the Company.
Stockholders’ Deficit
Stockholders' Equity Note Disclosure [Text Block]
Note 8 - Stockholders’ Deficit
 
Class A Preferred Shares
 
Pursuant to the Company’s Second Amended and Restated Certificate of Incorporation, filed September 13, 2016, Class A Common Stock was eliminated and 2,000,000 shares of Preferred Stock were authorized, of which 250,000 have been designated as Class A Preferred Stock and the remainder are undesignated preferred stock. The Class A Preferred Stock, with a par value of $0.0001 per share, is identical to undesignated Common Stock other than as to voting rights, conversion rights, and the PIK Dividend right (as described below). The undesignated Preferred Stock may be issued from time to time in one or more series. The Company’s Board of Directors is authorized to determine or alter the dividend rights, dividend rate, conversion rights, voting rights, rights and terms of redemption (including sinking fund provisions, if any), the redemption price or prices, the liquidation preferences and other designations, powers, preferences and relative, participating, optional or other special rights, if any, and the qualifications, limitations and restrictions granted to or imposed upon any wholly unissued series of Preferred Stock, and to fix the number of shares of any series of Preferred Stock (but not below the number of shares of any such series then outstanding).
 
The holders of the outstanding shares of Class A Preferred Stock shall receive on each February 17 (each a “PIK Dividend Payment Date”) after the original issuance date of the Class A Preferred Stock until the date all outstanding Class A Preferred Stock is converted into Common Stock or redeemed (and the purchase price is paid in full), pro rata per share dividends paid in additional fully paid and nonassessable shares of Common Stock (such dividend being herein called “PIK Dividends”) such that the aggregate number of shares of Common Stock issued pursuant to such PIK Dividend is equal to two and one-half percent (2.5%) of the Corporation’s fully-diluted outstanding capitalization on the date that is one (1) business day prior to any PIK Dividend Payment Date (“PIK Record Date”). In the event the Class A Preferred Stock converts into Common Stock, the holders shall receive all PIK Dividends accrued through the date of such conversion. No dividend or other distribution shall be paid, or declared and set apart for payment (other than dividends payable solely in capital stock on the capital stock of the Company) on the shares of Common Stock until all PIK Dividends on the Class A Preferred Stock shall have been paid or declared and set apart for payment. All dividends are non-cumulative.
 
On any matter presented to the stockholders of the Company for their action or consideration at any meeting of stockholders of the Company (or by written consent of stockholders in lieu of meeting), each holder of outstanding shares of Class A Preferred Stock shall be entitled to cast for each share of Class A Preferred Stock held by such holder as of the record date for determining stockholders entitled to vote on such matter, the number of votes that is equal to one and one-tenth (1.1) times a fraction, the numerator of which is the sum of (A) the number of shares of outstanding Common Stock and (B) the whole shares of Common Stock in to which the shares of outstanding Class A Common Stock and the Class A Preferred Stock are convertible, and the denominator of which is number of shares of outstanding Class A Preferred Stock (the “Class A Preferred Stock Ratio”). Thus, the Class A Preferred Stock will at all times constitute a voting majority.
 
Each share of Class A Preferred Stock is convertible, at the option of the holder, into one fully paid and nonassessable share of Common Stock (the “Conversion Ratio”), subject to certain adjustments. If the Company, at any time effects a subdivision or combination of the outstanding Common Stock (by any stock split, stock dividend, recapitalization, reverse stock split or otherwise), the applicable Conversion Ratio in effect immediately before that subdivision is proportionately decreased or increased, as applicable, so that the number of shares of Common Stock issuable on conversion of each share of Class A Preferred Stock shall be increased or decreased, a applicable, in proportion to such increase or decrease in the aggregate number of shares of Common Stock outstanding. Additionally, if any reorganization, recapitalization, reclassification, consolidation or merger involving the Company occurs in which the Common Stock (but not the Class A Preferred Stock) is converted into or exchanged for securities, cash or other property, then each share of Class A Preferred Stock becomes convertible into the kind and amount of securities, cash or other property which a holder of the number of shares of Common Stock of the Company issuable upon conversion of one share of the Class A Preferred Stock immediately prior to such reorganization, recapitalization, reclassification, consolidation or merger would have been entitled to receive pursuant to such transaction.
 
Common Stock
 
Our authorized capital stock will consist of 50,000,000 shares of common stock, with $0.0001 par value, and 2,000,000 shares of Preferred Stock, with $0.0001 par value, of which 250,000 have been designated as Class A Preferred Stock and the remainder are undesignated Preferred Stock.
 
Holders of our common stock are entitled to one vote for each share held on all matters submitted to a vote of stockholders and do not have cumulative voting rights. An election of directors by our stockholders shall be determined by a plurality of the votes cast by the stockholders entitled to vote on the election. Holders of common stock are entitled to receive proportionately any dividends as may be declared by our Board of Directors, subject to any preferential dividend rights of outstanding preferred stock.
 
In the event of our liquidation or dissolution, the holders of common stock are entitled to receive proportionately all assets available for distribution to stockholders after the payment of all debts and other liabilities and subject to the prior rights of any outstanding preferred stock. Holders of common stock have no preemptive, subscription, redemption or conversion rights. The rights, preferences and privileges of holders of common stock are subject to, and may be adversely affected by, the rights of the holders of shares of any series of preferred stock that we may designate and issue in the future.
 
Restricted Stock Awards
 
The following table summarizes unvested restricted stock award activity for the three months ended March 31, 2017.
 
 
 
 
 
Weighted
 
 
 
 
 
Average Grant
 
 
 
Number of Units
 
Date Fair Value
 
Unvested balance at December 31, 2016
 
 
825,000
 
$
0.15
 
Vested
 
 
-
 
 
-
 
Unvested balance at March 31, 2017
 
 
825,000
 
$
0.15
 
 
For the three months ended March 31, 2017 and 2016, stock-based compensation expenses associated with the amortization of restricted stock awards for employees and non-employees were approximately $5,000 and $9,000, respectively.
  
At March 31, 2017, the Company had unrecognized stock-based compensation expense related to restricted stock awards of approximately $19,000, which is expected to be recognized over the remaining weighted-average vesting period of 1.44 years.
Fair Value Measurement
Fair Value Disclosures [Text Block]
Note 9 - Fair Value Measurement
 
Financial instruments measured at fair value are classified in their entirety based on the lowest level of input that is significant to the fair value measurement. At March 31, 2017 and December 31, 2016, the warrant balance of approximately $311,000 and $314,000, respectively, was classified as Level 3 instruments.
 
The following table sets forth the changes in the estimated fair value for our Level 3 classified derivative contingently issuable warrant liability:
 
 
 
 
 
Westpark
 
 
 
 
 
NSC Contingently
 
Contingently
 
 
 
($ in thousands)
 
Issuable Warrants
 
Issuable Warrants
 
Total
 
Fair value, December 31, 2016
 
$
302
 
$
12
 
$
314
 
Change in fair value
 
 
(3)
 
 
-
 
 
(3)
 
Fair value, March 31, 2017
 
$
299
 
$
12
 
$
311
 
 
If the Company has an initial public offering and raises sufficient equity capital so that it has cash equal to five times the amount of the portion of the proceeds of the NSC Note transferred to it, then NSC will receive a warrant to purchase the Company’s stock equal to 25% of the outstanding note divided by the lowest price the Company sells its equity in its first third party financing. The warrants issued will have a term of 10 years and an exercise price equal to the par value of the Company’s common stock.  In accordance with ASC 815, the Company classifies the fair value of the warrant that may have been granted in connection with the NSC Note transferred to the Company as a derivative liability as there was a potential that the Company would not have a sufficient number of authorized common shares available to settle this instrument. The Company valued this warrant using a Black-Scholes model and used estimates for an expected dividend yield, a risk-free interest rate, and expected volatility together with management’s estimate of the probability of issuance of the warrant. At each reporting period, as long as the warrant was potentially issuable and there was a potential for an insufficient number of authorized shares available to settle the warrant, the warrant was revalued and any difference from the previous valuation date would be recognized as a change in fair value in the Company’s statement of operations.
 
The fair value of the NSC Contingently Issuable Warrants was determined by applying management’s estimate of the probability of issuance of the NSC Contingently Issuable Warrants together with the Black-Scholes option pricing model with the following key assumptions:
 
 
 
March 31, 2017
 
December 31, 2016
 
Risk-free interest rate
 
 
2.4
%
 
2.45
%
Expected dividend yield
 
 
-
 
 
-
 
Expected term in years
 
 
10
 
 
10
 
Expected volatility
 
 
83
%
 
83
%
Probability of issuance of the warrant
 
 
50
%
 
50
%
 
The following table sets forth the changes in the estimated fair value for our Level 3 classified convertible notes payable:
 
 
 
Westpark
 
($ in thousands)
 
Convertible Notes
 
Fair value, December 31, 2016
 
$
200
 
Change in fair value
 
 
4
 
Fair value, March 31, 2017
 
$
204
 
 
The fair value of Westpark warrant liability was measured at fair value using a Monte Carlo simulation valuation methodology. A summary of the weighted average (in aggregate) significant unobservable inputs (level 3 inputs) used in measuring the Company’s warrant liabilities that are categorized within Level 3 of the fair value hierarchy is as follows:
 
 
 
March 31,
 
December 31,
 
 
 
2017
 
2016
 
Risk-free interest rate
 
 
2.4
%
 
2.45
%
Expected dividend yield
 
 
-
 
 
-
 
Expected term in years
 
 
10
 
 
10
 
Expected volatility
 
 
86
%
 
87
%
Significant Accounting Policies (Policies)
Basis of Presentation
 
The accompanying unaudited interim condensed financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. In the opinion of management, the unaudited interim condensed financial statements reflect all adjustments, which include only normal recurring adjustments necessary for the fair statement of the balances and results for the periods presented. Certain information and footnote disclosures normally included in the Company’s annual financial statements prepared in accordance with GAAP have been condensed or omitted. These condensed financial statement results are not necessarily indicative of results to be expected for the full fiscal year or any future period.
 
Therefore, these condensed financial statements should be read in conjunction with the Company's audited financial statements and notes thereto for the year ended December 31, 2016, which were included in the Company’s Form 10-12 G/A, as amended, and filed with the U.S. Securities and Exchange Commission (“SEC”) on March 27, 2017. The results of operations for any interim periods are not necessarily indicative of the results that may be expected for the entire fiscal year or any other interim period.
 
The condensed financial statements may not be indicative of future performance and may not reflect what the results of operations, financial position, and cash flows would have been had Avenue operated as an independent entity. Certain estimates, including allocations from Fortress, have been made to provide financial statements for stand-alone reporting purposes. All inter-company transactions between Fortress and Avenue are classified as accrued expenses - related party in the financial statements. The Company believes that the assumptions underlying the financial statements are reasonable. The cost allocation methods applied to certain common costs include the following:
 
 
·
Specific identification.  Where the amounts were specifically identified to Avenue, they were classified accordingly.
 
·
Reasonable allocation.  Where the amounts were not clearly or specifically identified, management determined if a reasonable allocation method could be applied.  
Use of Estimates
 
The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.
Cash and Cash Equivalents
 
The Company considers all short-term investments with an original maturity of three months or less when purchased to be cash equivalents. There were no cash equivalents at March 31, 2017 and December 31, 2016. 
Research and Development
 
Research and development costs are expensed as incurred. Advance payments for goods and services that will be used in future research and development activities are expensed when the activity has been performed or when the goods have been received rather than when the payment is made. Upfront and milestone payments due to third parties that perform research and development services on the Company’s behalf will be expensed as services are rendered or when the milestone is probable. Costs incurred in obtaining technology licenses are charged to research and development expense if the technology licensed has not reached technological feasibility and has no alternative future use.
 
Research and development costs primarily consist of personnel related expenses, including salaries, benefits, travel, and other related expenses, stock-based compensation, payments made to third parties for license and milestone costs related to in-licensed products and technology, payments made to third party contract research organizations for preclinical and clinical studies, investigative sites for clinical trials, consultants, the cost of acquiring and manufacturing clinical trial materials, costs associated with regulatory filings and patents, laboratory costs and other supplies.
 
Costs incurred in obtaining technology licenses are charged to research and development expense if the technology licensed has not reached commercial feasibility and has no alternative future use. The licenses purchased by the Company require substantial completion of research and development, regulatory and marketing approval efforts in order to reach commercial feasibility and has no alternative future use. Accordingly, the total purchase price for the licenses acquired are reflected as research and development - licenses acquired on the Company’s Condensed Statement of Operations.
Annual Stock Dividend
 
In July 2016, in connection with the Amended and Restated Articles of Incorporation, the Company issued 250,000 Class A preferred shares to Fortress. The Class A preferred shares entitle the holder to a stock dividend equal to 2.5% of the fully diluted outstanding equity of the Company.
 
At December 31, 2016, the Company recorded the Annual Stock Dividend due to Fortress as contingent consideration. Contingent consideration is recorded when probable and reasonably estimable. The Company’s future share prices cannot be estimated due to the nature of its assets and the Company’s stage of development. Due to these uncertainties, the Company concluded that it could not reasonably estimate the contingent consideration until shares were actually issued on February 17, 2017. Because the issuance of shares on February 17, 2017 occurred prior to the issuance of the December 31, 2016 financial statements, the Company recorded approximately $49,000 in research and development - licenses acquired for the year ended December 31, 2016. On March 13, 2017, the Company issued the 250,595 common shares to Fortress and recorded an approximately $49,000 decrease in common shares issuable and a corresponding increase in additional paid in capital to account for the issuance of the PIK dividend.
Fair Value Measurement
 
The Company follows accounting guidance on fair value measurements for financial assets and liabilities measured at fair value on a recurring basis. Under the accounting guidance, fair value is defined as an exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. As such, fair value is a market-based measurement that should be determined based on assumptions that market participants would use in pricing an asset or a liability.
 
The accounting guidance requires fair value measurements be classified and disclosed in one of the following three categories:
 
Level 1: Quoted prices in active markets for identical assets or liabilities.
 
Level 2: Observable inputs other than Level 1 prices, for similar assets or liabilities that are directly or indirectly observable in the marketplace.
 
Level 3: Unobservable inputs which are supported by little or no market activity and that are financial instruments whose values are determined using pricing models, discounted cash flow methodologies, or similar techniques, as well as instruments for which the determination of fair value requires significant judgment or estimation.
 
The fair value hierarchy also requires an entity to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. Assets and liabilities measured at fair value are classified in their entirety based on the lowest level of input that is significant to the fair value measurement. The Company’s assessment of the significance of a particular input to the fair value measurement in its entirety requires management to make judgments and consider factors specific to the asset or liability.
Stock-Based Compensation
 
The Company expenses stock-based compensation to employees over the requisite service period based on the estimated grant-date fair value of the awards. For stock-based compensation awards to non-employees, the Company measures the fair value of the non-employee awards at each reporting period prior to vesting and finally at the vesting date of the award. Changes in the estimated fair value of these non-employee awards are recognized as compensation expense in the period of change.
 
The assumptions used in calculating the fair value of stock-based awards represent management’s best estimates and involve inherent uncertainties and the application of management’s judgment.
Valuation of Warrant Related to NSC Note
 
In accordance with ASC 815 Derivatives and Hedging, the Company classified the fair value of the warrant (“Contingently Issuable Warrants”) that it may be obligated to issue to NSC Biotech Venture Fund I, LLC (“NSC”), in connection with the transfer on October 31, 2015 of $3.0 million of indebtedness to NSC, as a derivative liability as there was a potential that the Company would not have a sufficient number of authorized common shares available to settle this instrument. The Company valued these Contingently Issuable Warrants using a Black-Scholes model and used estimates for an expected dividend yield, a risk-free interest rate, and expected volatility together with management’s estimate of the probability of issuance of the Contingently Issuable Warrants. At each reporting period, as long as the Contingently Issuable Warrants were potentially issuable and there was a potential for an insufficient number of authorized shares available to settle the Contingently Issuable Warrants, the Contingently Issuable Warrants should be revalued and any difference from the previous valuation date would be recognized as a change in fair value in the Company’s statement of operations.
Income Taxes
 
For purposes of these financial statements, the Company’s income tax expense and deferred tax balances have been recorded as if it filed tax returns on a stand-alone basis separate from Fortress.
 
Deferred tax assets and liabilities are determined based on the difference between the financial statement and tax bases of assets and liabilities measured at the enacted tax rates in effect for the year in which these items are expected to reverse. Deferred tax assets are reduced by valuation allowances if, based on the consideration of all available evidence, it is more likely than not that some portion or all of the deferred tax asset will not be realized.
Net loss per Share
 
Loss per share is computed by dividing net loss by the weighted-average number of common shares outstanding, excluding unvested restricted stock, during the period. Since dividends are declared paid and set aside among the holders of shares of common stock and Class A common stock pro-rata on an as-if-converted basis, the two-class method of computing net loss per share is not required. In the calculation of diluted loss per share, since there was no option or warrants as well as the conversion of rights, the diluted loss per share equaled the basic loss per share during the period.
Recently Adopted Accounting Standards
  
In August 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standard Update (“ASU”) 2014-15, Presentation of Financial Statements - Going Concern (Topic 915): Disclosure of Uncertainties about an Entity's Ability to Continue as a Going Concern (“ASU 2014-15”). ASU 2014-15 states that in connection with preparing financial statements for each annual and interim reporting period, an entity's management should evaluate whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the entity's ability to continue as a going concern within one year after the date that the financial statements are issued (or within one year after the date that the financial statements are available to be issued when applicable). ASU 2014-15 will be effective for annual and interim periods beginning on or after December 15, 2016. The Company adopted ASU No. 2014-15 2016, and its adoption did not have a material impact on the Company’s condensed financial statements.
 
In March 2016, the FASB issued ASU No. 2016-09 Compensation-Stock Compensation (Topic 718), Improvements to Employee Share-Based Payment Accounting (“ASU 2016-09”). Under ASU 2016-09, companies will no longer record excess tax benefits and certain tax deficiencies in additional paid-in capital (“APIC”). Instead, they will record all excess tax benefits and tax deficiencies as income tax expense or benefit in the income statement and the APIC pools will be eliminated. In addition, ASU 2016-09 eliminates the requirement that excess tax benefits be realized before companies can recognize them. ASU 2016-09 also requires companies to present excess tax benefits as an operating activity on the statement of cash flows rather than as a financing activity. Furthermore, ASU 2016-09 will increase the amount an employer can withhold to cover income taxes on awards and still qualify for the exception to liability classification for shares used to satisfy the employer’s statutory income tax withholding obligation. An employer with a statutory income tax withholding obligation will now be allowed to withhold shares with a fair value up to the amount of taxes owed using the maximum statutory tax rate in the employee’s applicable jurisdiction(s). ASU 2016-09 requires a company to classify the cash paid to a tax authority when shares are withheld to satisfy its statutory income tax withholding obligation as a financing activity on the statement of cash flows. Under current GAAP, it was not specified how these cash flows should be classified. In addition, companies will now have to elect whether to account for forfeitures on share-based payments by (1) recognizing forfeitures of awards as they occur or (2) estimating the number of awards expected to be forfeited and adjusting the estimate when it is likely to change, as is currently required. The Amendments of this ASU are effective for reporting periods beginning after December 15, 2016, with early adoption permitted but all of the guidance must be adopted in the same period. The Company adopted ASU 2016-09 in the first quarter of 2017, and its adoption did not have a material impact on the Company’s condensed financial statements. 
Notes Payable (Tables)
Schedule of Long-term Debt Instruments [Table Text Block]
The following table summarizes NSC Note activities for the three months ended March 31, 2017:
 
($ in thousands)
 
Note Payable
 
Discount
 
Note Payable, Net
 
December 31, 2016 balance
 
$
3,000
 
$
(174)
 
$
2,826
 
Amortization of debt discount
 
 
-
 
 
33
 
 
33
 
March 31, 2017 balance
 
 
3,000
 
 
(141)
 
 
2,859
 
Less: NSC notes payable, short term
 
 
(1,750)
 
 
-
 
 
(1,750)
 
NSC notes payable, long term
 
$
1,250
 
$
(141)
 
$
1,109
 
Stockholders’ Deficit (Tables)
Schedule of Unvested Restricted Stock Units Roll Forward [Table Text Block]
The following table summarizes unvested restricted stock award activity for the three months ended March 31, 2017.
 
 
 
 
 
Weighted
 
 
 
 
 
Average Grant
 
 
 
Number of Units
 
Date Fair Value
 
Unvested balance at December 31, 2016
 
 
825,000
 
$
0.15
 
Vested
 
 
-
 
 
-
 
Unvested balance at March 31, 2017
 
 
825,000
 
$
0.15
 
Fair Value Measurement (Tables)
The fair value of the NSC Contingently Issuable Warrants was determined by applying management’s estimate of the probability of issuance of the NSC Contingently Issuable Warrants together with the Black-Scholes option pricing model with the following key assumptions:
 
 
 
March 31, 2017
 
December 31, 2016
 
Risk-free interest rate
 
 
2.4
%
 
2.45
%
Expected dividend yield
 
 
-
 
 
-
 
Expected term in years
 
 
10
 
 
10
 
Expected volatility
 
 
83
%
 
83
%
Probability of issuance of the warrant
 
 
50
%
 
50
%
The fair value of Westpark warrant liability was measured at fair value using a Monte Carlo simulation valuation methodology. A summary of the weighted average (in aggregate) significant unobservable inputs (level 3 inputs) used in measuring the Company’s warrant liabilities that are categorized within Level 3 of the fair value hierarchy is as follows:
 
 
 
March 31,
 
December 31,
 
 
 
2017
 
2016
 
Risk-free interest rate
 
 
2.4
%
 
2.45
%
Expected dividend yield
 
 
-
 
 
-
 
Expected term in years
 
 
10
 
 
10
 
Expected volatility
 
 
86
%
 
87
%
The following table sets forth the changes in the estimated fair value for our Level 3 classified derivative contingently issuable warrant liability:
 
 
 
 
 
Westpark
 
 
 
 
 
NSC Contingently
 
Contingently
 
 
 
($ in thousands)
 
Issuable Warrants
 
Issuable Warrants
 
Total
 
Fair value, December 31, 2016
 
$
302
 
$
12
 
$
314
 
Change in fair value
 
 
(3)
 
 
-
 
 
(3)
 
Fair value, March 31, 2017
 
$
299
 
$
12
 
$
311
 
The following table sets forth the changes in the estimated fair value for our Level 3 classified convertible notes payable:
 
 
 
Westpark
 
($ in thousands)
 
Convertible Notes
 
Fair value, December 31, 2016
 
$
200
 
Change in fair value
 
 
4
 
Fair value, March 31, 2017
 
$
204
 
Organization, Plan of Business Operations and Going Concern Consideration (Details Textual) (USD $)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Working Capital Deficit
$ 7,600,000 
 
 
Stockholders' Equity Attributable to Parent
(8,904,000)
 
(8,248,000)
Proceeds from Notes Payable
71,000 
875,000 
 
Long-term Line of Credit
2,900,000 
 
 
NSC Biotech Venture Fund I, LLC [Member]
 
 
 
Proceeds from Notes Payable
$ 3,000,000 
 
 
Significant Accounting Policies (Details Textual) (USD $)
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2017
Jul. 31, 2016
Mar. 31, 2017
Dec. 31, 2016
Stock Issued During Period, Shares, New Issues
 
250,000 
 
 
Preferred Stock, Dividend Rate, Percentage
 
2.50% 
 
 
Research and Development in Process
 
 
$ 49,000 
$ 49,000 
Stock Issued During Period, Value, New Issues
 
 
 
Debt Instrument, Decrease, Forgiveness
3,000,000 
 
 
 
Convertible Common Stock [Member]
 
 
 
 
Stock Issued During Period, Shares, New Issues
 
 
250,595 
 
Common Stock issuable [Member]
 
 
 
 
Stock Issued During Period, Value, New Issues
 
 
49,000 
 
Common Stock Including Additional Paid in Capital [Member]
 
 
 
 
Stock Issued During Period, Value, New Issues
 
 
$ 49,000 
 
Allocation (Details Textual) (USD $)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Allocated Share-based Compensation Expense
$ 95,000 
$ 81,000 
Research and Development Expense [Member]
 
 
Share Based Compensation Allocation Percentage
50.00% 
 
General and Administrative Expense [Member]
 
 
Share Based Compensation Allocation Percentage
50.00% 
 
Consulting Agreement (Details Textual) (Scenario, Actual [Member], USD $)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Mar. 31, 2015
Scenario, Actual [Member]
 
 
 
Professional Fees
$ 0 
$ 16,667 
$ 25,000 
Related Party Agreements (Details Textual) (USD $)
3 Months Ended 1 Months Ended 3 Months Ended 1 Months Ended 3 Months Ended 1 Months Ended 1 Months Ended
Mar. 31, 2017
Mar. 31, 2017
Fortress Note [Member]
Mar. 31, 2016
Fortress Note [Member]
Mar. 15, 2015
Fortress Note [Member]
Sep. 30, 2016
National Holdings, Inc. [Member]
Jun. 30, 2015
Chord Advisors, LLC [Member]
Mar. 31, 2017
Chord Advisors, LLC [Member]
Mar. 31, 2016
Chord Advisors, LLC [Member]
Jun. 30, 2015
Chord Advisors, LLC [Member]
Prior to Public Company [Member]
Feb. 17, 2015
Asset Management Income [Member]
Mar. 31, 2017
Asset Management Income [Member]
Mar. 31, 2016
Asset Management Income [Member]
Sep. 30, 2016
AR Founders Agreement [Member]
Sep. 30, 2016
AR Founders Agreement [Member]
Common Stock [Member]
Feb. 17, 2015
Fortress Biotech, Inc [Member]
Sep. 30, 2016
Preferred Class A [Member]
AR Founders Agreement [Member]
Sep. 30, 2016
Common Class A [Member]
AR Founders Agreement [Member]
Long-term Debt, Gross
 
 
 
 
 
 
 
 
 
 
 
 
 
 
$ 3,000,000 
 
 
Agreement Description Terms
(i) issue annually to Fortress, on the anniversary date of the Founders Agreement, shares of common stock equal to two and one half percent (2.5%) of the fully-diluted outstanding equity of Avenue at the time of issuance; (ii) pay an equity fee in shares of Avenue common stock, payable within five (5) business days of the closing of any equity or debt financing for Avenue or any of its respective subsidiaries that occurs after the effective date of the Founders Agreement and ending on the date when Fortress no longer has majority voting control in Avenues voting equity, equal to two and one half percent (2.5%) of the gross amount of any such equity or debt financing; and (iii) pay a cash fee equal to four and one half percent (4.5%) of Avenues annual net sales, payable on an annual basis, within ninety (90) days of the end of each calendar year. In the event of a change in control (as it is defined in the Founders Agreement), Fortress will be paid a one-time change in control fee equal to five (5x) times the product of (i) net sales for the twelve (12) months immediately preceding the change in control and (ii) four and one-half percent (4.5%). 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Number of shares Exchanged
 
 
 
 
 
 
 
 
 
 
 
 
 
7,400,000 
 
250,000 
7,000,000 
Annual Consulting Fee
 
 
 
 
 
 
 
 
 
500,000 
125,000 
125,000 
 
 
 
 
 
Increase In Annual Consulting Fee
 
 
 
 
 
 
 
 
 
1,000,000 
 
 
 
 
 
 
 
Excess In Net Assets Value
 
 
 
 
 
 
 
 
 
100,000,000 
 
 
 
 
 
 
 
Debt Instrument, Interest Rate, Stated Percentage
 
 
 
8.00% 
 
 
 
 
 
 
 
 
 
 
 
 
 
Long-term Debt
 
2,900,000 
 
 
3,000,000 
 
 
 
 
 
 
 
 
 
 
 
 
Interest Expense, Debt
 
57,000 
29,000 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Annual Advisory Service Fee
 
 
 
 
 
$ 7,500 
$ 15,000 
$ 20,000 
$ 5,000 
 
 
 
 
 
 
 
 
Business Acquisition, Percentage of Voting Interests Acquired
 
 
 
 
56.60% 
 
 
 
 
 
 
 
 
 
 
 
 
Placement Fee, Percentage
 
 
 
 
10.00% 
 
 
 
 
 
 
 
 
 
 
 
 
Amended Founders Agreements Terms
 
 
 
 
 
 
 
 
 
 
 
 
15 years 
 
 
 
 
Notes Payable (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Note Payable, Net Amortization of debt discount
$ 33 
$ 29 
 
Note Payable, Net NSC notes payable, long term
1,109 
 
1,826 
NSC Notes Memebers [Member]
 
 
 
Note Payable Beginning
3,000 
 
 
Note Payable Ending
3,000 
 
 
Note Payable Less: NSC notes payable, short term
(1,750)
 
 
Note Payable NSC notes payable, long term
1,250 
 
 
Discount Beginning
(174)
 
 
Discount Ending
(141)
 
 
Discount Less: NSC notes payable, short term
 
 
Discount NSC notes payable, long term
(141)
 
 
Notes Payable, Net Beginning
2,826 
 
 
Note Payable, Net Amortization of debt discount
33 
 
 
Notes Payable, Net Ending
2,859 
 
 
Note Payable, Net Less: NSC notes payable, short term
(1,750)
 
 
Note Payable, Net NSC notes payable, long term
$ 1,109 
 
 
Notes Payable (Details Textual) (NSC Notes Memebers [Member], USD $)
In Millions, unless otherwise specified
1 Months Ended
Feb. 17, 2015
NSC Notes Memebers [Member]
 
Debt Instrument, Face Amount
$ 3.0 
Debt Instrument, Term
30 months 
Debt Instrument, Interest Rate, Stated Percentage
8.00% 
Debt Instrument, Payment Terms
No principal amounts are due from the Company for the first twenty-four months (or the first thirty months if the maturity date is extended). Thereafter, the NSC Note must be repaid at the rate of 1/12th of the principal amount per month for a period of 12 months. 
Stockholders’ Deficit (Details) (Restricted Stock [Member], USD $)
3 Months Ended
Mar. 31, 2017
Restricted Stock [Member]
 
Number of Units, Unvested Beginning Balance
825,000 
Number of Units, Vested
Number of Units, Unvested Ending Balance
825,000 
Weighted Average Grant Date Fair Value, Unvested Beginning Balance
$ 0.15 
Weighted Average Grant Date Fair Value, Vested
$ 0 
Weighted Average Grant Date Fair Value, Unvested Ending Balance
$ 0.15 
Stockholders’ Deficit (Details Textual) (USD $)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Preferred Stock, Shares Authorized
2,000,000 
 
2,000,000 
Common Stock, Shares Authorized
50,000,000 
 
50,000,000 
Common Stock, Par or Stated Value Per Share
$ 0.0001 
 
$ 0.0001 
Share-based Compensation
$ 5,000 
$ 9,000 
 
Restricted Stock [Member]
 
 
 
Share-based Compensation
5,000 
9,000 
 
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Share-based Awards Other than Options
$ 19,000 
 
 
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition
1 year 5 months 8 days 
 
 
Preferred Class A [Member]
 
 
 
Preferred Stock, Shares Authorized
250,000 
 
 
Fair Value Measurement (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2017
Westpark Contingently Issuable Warrants [Member]
 
Fair value, Beginning Balance
$ 12 
Change in fair value
Fair value, Ending Balance
12 
NSC Contingently Issuable Warrants [Member]
 
Fair value, Beginning Balance
302 
Change in fair value
(3)
Fair value, Ending Balance
299 
Warrant [Member]
 
Fair value, Beginning Balance
314 
Change in fair value
(3)
Fair value, Ending Balance
$ 311 
Fair Value Measurement (Details 1) (NSC Contingently Issuable Warrants [Member])
3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2016
NSC Contingently Issuable Warrants [Member]
 
 
Risk-free interest rate
2.40% 
2.45% 
Expected dividend yield
0.00% 
0.00% 
Expected term in years
10 years 
10 years 
Expected volatility
83.00% 
83.00% 
Probability of issuance of the warrant
50.00% 
50.00% 
Fair Value Measurement (Details 2) (Debt [Member], USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2017
Debt [Member]
 
Fair value, Beginning Balance
$ 200 
Change in fair value
Fair value, Ending Balance
$ 204 
Fair Value Measurement (Details 3) (Westpark Contingently Issuable Warrants [Member])
3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Westpark Contingently Issuable Warrants [Member]
 
 
Risk-free interest rate
2.40% 
2.45% 
Expected dividend yield
0.00% 
0.00% 
Expected term in years
10 years 
10 years 
Expected volatility
86.00% 
87.00% 
Fair Value Measurement (Details Textual) (USD $)
3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Mar. 31, 2017
NSC Contingently Issuable Warrants [Member]
Warrants Not Settleable in Cash, Fair Value Disclosure
$ 311,000 
$ 314,000 
 
Percentage Of Shares Received Under Purchase Agreement
 
 
25.00% 
Warrant Expiration Period
 
 
10 years