FORM 4
☐ Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
☐ Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

SCULLY WILLIAM P		 2. Issuer Name and Ticker or Trading Symbol

PROTHENA CORP PUBLIC LTD CO [ PRTA ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    __X__ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

771 MANATEE COVE		 3. Date of Earliest Transaction (MM/DD/YYYY)

12/18/2024
(Street)

VERO BEACH, FL 32963		 4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)        (State)        (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares, par value $0.01 per share 12/18/2024  G  430,000 A$0 1,224,257 D  
Ordinary Shares, par value $0.01 per share 12/18/2024  P  73,436 A$13.926 (1)1,297,693 D  
Ordinary Shares, par value $0.01 per share 12/19/2024  G  681,000 D$0 616,693 D  
Ordinary Shares, par value $0.01 per share 12/20/2024  P  2,000 A$15.9065 618,693 D  
Ordinary Shares, par value $0.01 per share 12/20/2024  G  500 D$0 618,193 D  
Ordinary Shares, par value $0.01 per share 12/31/2024  P  1,200 A$13.3652 619,393 D  
Ordinary Shares, par value $0.01 per share 12/31/2024  P  800 A$13.394 620,193 D  
Ordinary Shares, par value $0.01 per share 12/31/2024  P  30,000 A$12.988 (2)650,193 D  
Ordinary Shares, par value $0.01 per share 1/2/2025  G  13,200 D$0 636,993 D  
Ordinary Shares, par value $0.01 per share 1/3/2025  G  1,000 D$0 635,993 D  
Ordinary Shares, par value $0.01 per share 1/14/2025  P  100,000 A$12.7904 (3)735,993 D  
Ordinary Shares, par value $0.01 per share 12/20/2024  G  40,000 D$0 59,000 I By Spouse 
Ordinary Shares, par value $0.01 per share 1/15/2025  G  12,000 D$0 47,000 I By Spouse 
Ordinary Shares, par value $0.01 per share         75,950 I By Manatee Equity Fund LLC (4)
Ordinary Shares, par value $0.01 per share         68,000 I By Self as Trustee for The 2012 Randolph Scully Family Trust 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
(1) The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $13.85 to $14.00, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1), (2), and (3) to this Form 4.
(2) The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.93 to $13.07, inclusive.
(3) The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.41 to $12.94, inclusive.
(4) The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
SCULLY WILLIAM P
771 MANATEE COVE
VERO BEACH, FL 32963
X
Signatures
/s/ Diana L. Hayes by POA from William P. Scully5/2/2025
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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