REDHILL BIOPHARMA LTD., 20-F filed on 4/10/2025
Annual and Transition Report (foreign private issuer)
v3.25.1
Document and Entity Information
12 Months Ended
Dec. 31, 2024
shares
Document Information [Line Items]  
Document Type 20-F
Document Registration Statement false
Document Annual Report true
Document Period End Date Dec. 31, 2024
Document Transition Report false
Document Shell Company Report false
Entity File Number 001-35773
Entity Registrant Name RedHill Biopharma Ltd.
Entity Incorporation, State or Country Code L3
Entity Address, Address Line One 21 Ha’arba’a Street
Entity Address, City or Town Tel Aviv
Entity Address, Postal Zip Code 6473921
Entity Address, Country IL
Entity Common Stock, Shares Outstanding 12,899,831,000
Entity Well-known Seasoned Issuer No
Entity Voluntary Filers No
Entity Current Reporting Status Yes
Entity Interactive Data Current Yes
Entity Filer Category Non-accelerated Filer
Entity Emerging Growth Company false
ICFR Auditor Attestation Flag false
Document Financial Statement Error Correction [Flag] false
Document Accounting Standard International Financial Reporting Standards
Entity Shell Company false
Auditor Name Kesselman & Kesselman
Auditor Location Tel-Aviv, Israel
Auditor Firm ID 1309
Entity Central Index Key 0001553846
Current Fiscal Year End Date --12-31
Document Fiscal Year Focus 2024
Document Fiscal Period Focus FY
Amendment Flag false
ADS  
Document Information [Line Items]  
Title of 12(b) Security American Depositary Shares, each representing ten thousand (10,000) Ordinary Shares (1)
Trading Symbol RDHL
Security Exchange Name NASDAQ
Ordinary shares  
Document Information [Line Items]  
Title of 12(b) Security Ordinary Shares, par value NIS 0.01 per share (2)
Business contact  
Document Information [Line Items]  
Contact Personnel Name Razi Ingber
Entity Address, Address Line One 21 Ha’arba’a Street
Entity Address, City or Town Tel Aviv
Entity Address, Postal Zip Code 6473921
Entity Address, Country IL
City Area Code 972
Local Phone Number 3-541-3131
Contact Personnel Fax Number 972-3-541-3144
v3.25.1
CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)      
NET REVENUES $ 8,043 $ 6,530 $ 61,800
COST OF REVENUES 3,192 3,459 33,337
GROSS PROFIT 4,851 3,071 28,463
RESEARCH AND DEVELOPMENT EXPENSES 1,588 3,528 7,279
SELLING AND MARKETING EXPENSES 5,950 14,756 35,442
GENERAL AND ADMINISTRATIVE EXPENSES 9,567 16,219 28,586
OTHER INCOME (EXPENSES) (2,359) 44,064  
OPERATING INCOME (LOSS) (14,613) 12,632 (42,844)
FINANCIAL INCOME 8,401 20,889 13,562
FINANCIAL EXPENSES 2,056 9,605 42,387
Financial income (expenses), net 6,345 11,284 (28,825)
INCOME (LOSS) AND COMPREHENSIVE INCOME (LOSS) FOR THE YEAR $ (8,268) $ 23,916 $ (71,669)
EARNINGS (LOSS) PER ORDINARY SHARE, basic (U.S. dollars) $ 0 $ 0.01 $ (0.12)
EARNINGS (LOSS) PER ORDINARY SHARE, diluted (U.S. dollars) $ 0 $ 0.01 $ (0.12)
v3.25.1
CONSOLIDATED STATEMENTS OF FINANCIAL POSITION - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
CURRENT ASSETS:    
Cash and cash equivalents $ 4,617 $ 5,569
Restricted cash   790
Trade receivables 2,539 2,591
Prepaid expenses and other receivables 1,104 2,801
Inventory 3,651 4,389
Total current assets 11,911 16,140
NON-CURRENT ASSETS:    
Restricted cash 148 147
Fixed assets 135 193
Right-of-use assets 302 989
Intangible assets 5,547 5,578
Total non-current assets 6,132 6,907
TOTAL ASSETS 18,043 23,047
CURRENT LIABILITIES:    
Account payable 1,168 3,278
Lease liabilities 353 718
Allowance for deductions from revenue 9,288 10,654
Derivative financial instruments 1,421 741
Accrued expenses and other current liabilities 9,993 4,592
Total current liabilities 22,223 19,983
NON-CURRENT LIABILITIES:    
Lease liabilities 3 455
Royalty obligation 500 540
Total non-current liabilities 503 995
TOTAL LIABILITIES 22,726 20,978
EQUITY (CAPITAL DEFICIENCY):    
Ordinary shares 35,036 21,441
Additional paid-in capital 375,082 388,363
Accumulated deficit (414,801) (407,735)
TOTAL EQUITY (CAPITAL DEFICIENCY) (4,683) 2,069
TOTAL LIABILITIES AND EQUITY (CAPITAL DEFICIENCY) $ 18,043 $ 23,047
v3.25.1
CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY (CAPITAL DEFICIENCY) - USD ($)
$ in Thousands
Ordinary shares.
Additional paid-in capitals
Accumulated deficit
Total
Balance at beginning of period at Dec. 31, 2021 $ 1,495 $ 375,246 $ (367,866) $ 8,875
Share-based compensation to employees and service providers     5,675 5,675
Issuance of ordinary shares, net of issuance costs 1,326 7,393   8,719
Issuance Of Ordinary Shares For Vested RSUs 14 (14)    
Comprehensive income (loss)     (71,669) (71,669)
Balance at end of period at Dec. 31, 2022 2,835 382,625 (433,860) (48,400)
Share-based compensation to employees and service providers     2,209 2,209
Issuance of ordinary shares, net of issuance costs 18,556 5,788   24,344
Issuance Of Ordinary Shares For Vested RSUs 50 (50)    
Comprehensive income (loss)     23,916 23,916
Balance at end of period at Dec. 31, 2023 21,441 388,363 (407,735) 2,069
Share-based compensation to employees and service providers     1,202 1,202
Issuance of ordinary shares, net of issuance costs 13,135 (12,821)   314
Issuance Of Ordinary Shares For Vested RSUs 460 (460)    
Comprehensive income (loss)     (8,268) (8,268)
Balance at end of period at Dec. 31, 2024 $ 35,036 $ 375,082 $ (414,801) $ (4,683)
v3.25.1
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
OPERATING ACTIVITIES:      
Income (loss) $ (8,268) $ 23,916 $ (71,669)
Adjustments in respect of income and expenses not involving cash flow:      
Share-based compensation to employees and service providers 665 1,647 5,675
Depreciation 588 1,445 2,136
Amortization of intangible assets 31 545 6,018
Gains from the transfer of rights in Movantik and extinguishment of debt obligations, see below   (56,082)  
Gains from early termination of leases, and impairment of fixed assets, net (22) (543)  
Non-cash expenses related to borrowing and payable in respect of intangible assets purchase     33,151
Loss from global termination agreement (See note 15(6)(b)) and below 2,359    
Fair value (gains) losses on derivative financial instruments, recognition of day 1 loss and changes in royalty obligation (8,268) 5,359 (13,422)
Loss from modification of warrants terms as part of a new issuance, see notes 17(d) and 17(f)   1,459  
Issuance costs in respect of warrants 1,497 2,034 958
Exchange differences and revaluation of bank deposit (4) 19 (40)
Total adjustments in respect of income and expenses not involving cash flow (3,154) (44,117) 34,476
Changes in assets and liability items:      
Decrease (increase) in trade receivables 52 31,930 (2,845)
Decrease in prepaid expenses and other receivables 1,697 1,586 274
Decrease in inventories 738 2,387 3,801
Decrease in accounts payable (2,110) (952) (7,434)
Decrease in accrued expenses and other liabilities 3,042 (13,354) (2,947)
Increase (decrease) in allowance for deductions from revenue (1,366) (37,216) 17,159
Total changes in assets and liability items 2,053 (15,619) 8,008
Net cash used in operating activities (9,369) (35,820) (29,185)
INVESTING ACTIVITIES:      
Purchase of fixed assets (9) (11) (198)
Change in investment in current bank deposits   15 8,500
Net cash provided by (used in) investing activities (9) 4 8,302
FINANCING ACTIVITIES:      
Proceeds from issuance of ordinary shares and warrants, net of issuance costs 8,263 13,959 23,806
Repayment of payable in respect of intangible asset purchase   (6,555) (10,878)
Decrease in restricted cash 790 15,210  
Payment of principal with respect to lease liabilities (636) (1,175) (1,475)
Net cash provided by financing activities 8,417 21,439 11,453
DECREASE IN CASH AND CASH EQUIVALENTS (961) (14,377) (9,430)
EXCHANGE DIFFERENCES ON CASH AND CASH EQUIVALENTS 9 (22) (76)
BALANCE OF CASH AND CASH EQUIVALENTS AT THE BEGINNING OF PERIOD 5,569 19,968 29,474
BALANCE OF CASH AND CASH EQUIVALENTS AT THE END OF PERIOD 4,617 5,569 19,968
SUPPLEMENTARY INFORMATION ON INTEREST RECEIVED IN CASH 131 138 84
SUPPLEMENTARY INFORMATION ON INTEREST PAID IN CASH 55 367 8,182
Acquisition of right-of-use assets by means of lease liabilities   270 5,590
Decrease in lease liability (with corresponding decrease in right of use asset in amount of $166 in 2024, and $4,697 in 2023) resulting from early termination of lease. $ 188 5,413 $ 587
Decrease in Intangible asset   (59,503)  
Decrease in Inventories   (4,233)  
Decrease in Payable in respect of Intangible asset   4,602  
Decrease in Borrowing   115,216  
Gains from the transfer of the rights in Movantik and extinguishment of debt obligations   $ 56,082  
v3.25.1
CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
CONSOLIDATED STATEMENTS OF CASH FLOWS    
Decrease in right o fuse assets $ 166 $ 4,697
v3.25.1
GENERAL
12 Months Ended
Dec. 31, 2024
GENERAL  
GENERAL

NOTE 1 - GENERAL:

a.  General:

1)RedHill Biopharma Ltd. (the “Company”), incorporated on August 3, 2009, together with its wholly-owned subsidiary, RedHill Biopharma Inc. (“RedHill Inc.”), incorporated in Delaware, U.S. on January 19, 2017, is a specialty biopharmaceutical company primarily focused on gastrointestinal (“GI”) diseases and infectious diseases.

     The Company’s ordinary shares were traded on the Tel-Aviv Stock Exchange (“TASE”) from February 2011 to February 2020, after which the Company voluntarily delisted from trading on the TASE, effective February 13, 2020. The Company’s American Depositary Shares (“ADSs”) were traded on the Nasdaq Capital Market from December 27, 2012, were listed on the Nasdaq Global Market (“Nasdaq”) from July 20, 2018, and have been again listed on the Nasdaq Capital Market since November 15, 2023.

On March 23, 2023, the Company changed the ADS ratio from 1 ADS representing 10 ordinary shares to 1 ADS representing 400 ordinary shares. On August 20, 2024, the Company changed the ADS to ordinary share ratio from 1 ADS representing 400 ordinary shares to 1 ADS representing 10,000 ordinary shares. All data denominated in ADS were adjusted for these ratio changes.

The Company’s registered address is 21 Ha’arba’a St, Tel-Aviv, Israel.

2)Since the Company established its commercial presence in the U.S. in 2017, it has promoted or commercialized various GI-related products that were either developed internally or acquired through in-licensing agreements. As of the date of approval of these financial statements, the Company commercializes in the U.S. Talicia®, for the treatment of Helicobacter pylori infection in adults, the first product approved by the U.S. Food and Drug Administration (“FDA”) being developed primarily internally by the Company. Until February 1, 2023, the Company commercialized Movantik® in the U.S, for the treatment of opioid-induced constipation. See also note 15 (6) regarding the transfer of the Company’s rights in Movantik® to HCR Collateral Management, LLC (“HCRM”) in exchange for all the Company’s debt obligations under the Credit Agreement with HCRM, as well as the Global Termination Agreement, which terminated all remaining credit ties related to this transaction. The Company also continues to advance the development part of its late-stage therapeutic candidates.
3) Through December 31, 2024, the Company has an accumulated deficit and negative working capital, and its activities have been funded primarily through public and private offerings of the Company’s securities and senior secured borrowing (now fully extinguished, see note 15(6)). There is no assurance that the Company’s business will generate sustainable positive cash flows to fund its business.

The Company plans to further fund its future operations through commercialization and out-licensing of its therapeutic candidates, commercialization of in-licensed or acquired products and raising additional capital through equity or debt financing or through other non-dilutive financing. Furthermore, the Company actively pursuing and in discussions with multiple parties regarding strategic business transaction although there is no guarantee the discussions will result in any strategic business transactions. The Company’s current cash resources are not sufficient to complete the research and development of any or all of its therapeutic candidates and to fully support its commercial operations until generation of sustainable positive cash flows. Management expects that the Company will incur additional losses as it continues to focus its resources on advancing the development of its therapeutic candidates, as well as advancing its commercial operations, based on a prioritized plan that will result in negative cash flows from operating activities. Management believes that there is presently insufficient funding available to allow the Company to fund its activities for a period exceeding one year from the date of this filing. These conditions and events indicate that a material uncertainty exists that may cast significant doubt (or raise substantial doubt as contemplated by PCAOB standards) about the Company’s ability to continue as a going concern.

The accompanying financial statements have been prepared assuming that the Company will continue as a going concern and do not include any adjustments that might result from the outcome of this uncertainty.

4)    In October 2023, Israel was attacked by a terrorist organization and entered a state of war. As of the date of these consolidated financial statements, sustained conflict in the region is ongoing. During the year ended December 31, 2024 and 2023, the impact of this war on the Company results and financial condition was immaterial, but such impact may increase.

b. Approval of the financial statements:

The date of the approval of these financial statements by the Board of Directors (the "BoD") is April 10, 2025.

v3.25.1
SUMMARY OF MATERIAL ACCOUNTING POLICIES
12 Months Ended
Dec. 31, 2024
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES  
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

NOTE 2 - SUMMARY OF MATERIAL ACCOUNTING POLICIES:

a.    Basis for presentation of the financial statements

The consolidated financial statements of the Company have been prepared in accordance with IFRS Accounting Standards as issued by the International Accounting Standards Board. (“IASB”).

The material accounting policies described below have been applied consistently in relation to all the periods presented, except for the adoption of IAS 1 amendments effective January 1, 2024, as described in note 2(m)(1).

The preparation of financial statements in conformity with IFRS requires the use of certain critical accounting estimates. It also requires management to exercise its judgment in applying the Company’s accounting policies. The areas involving a higher degree of judgment or complexity, or areas where assumptions and estimates are material to the financial statements, are disclosed in note 3. Actual results could differ significantly from those estimates and assumptions.

b.    Translation of foreign currency transactions and balances

1)    Functional and presentation currency

Items included in the consolidated financial statements are measured using the currency of the primary economic environment in which the Company and its subsidiary operate (the “Functional Currency”). The consolidated financial statements are presented in U.S. dollars (“$”), which is the Company’s functional and presentation currency.

2)   Transactions and balances

Foreign currency transactions in currencies different from the Functional Currency (hereafter foreign currency, mostly New Israeli Shekel (“NIS”) and Euro are translated into the Functional Currency using the exchange rates at the dates of the transactions. Foreign exchange differences resulting from the settlement of such transactions and from the translation of period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recorded in the Consolidated Statements of Comprehensive Income (Loss) under financial income or financial expenses.

c.    Trade receivables  

Trade receivables are recognized initially at the amount of consideration that is unconditional. They are subsequently measured at amortized cost, less allowance for expected credit losses. The Company measures the loss allowance for expected credit losses on trade receivables based on lifetime expected credit losses.

d.     Inventory

The Company’s inventory is stated at the lower of cost or net realizable value. Cost of inventory is determined using the first-in, first-out method.

Net realizable value is the estimated selling price in the ordinary course of business, less the estimated costs of completion and the estimated costs necessary to make the sale.

The Company continually evaluates inventory for potential loss due to excess quantity or obsolete or slow-moving inventory by comparing sales history and sales projections to the inventory on hand. When evidence indicates that the carrying value of a product may not be recoverable, a charge is recorded to reduce the inventory to its current net realizable value.

                    e. Fixed assets

                           

Fixed assets items are stated at cost less accumulated depreciation.

Depreciation is computed by the straight-line method, to reduce the cost of fixed assets to their residual value over their estimated useful lives as follows:

    

%

 

Computer equipment

33

Office furniture and equipment

8-15

Leasehold improvements are depreciated by the straight-line method over the shorter of the term of the lease or the estimated useful life of the improvements.

f.    Intangible assets

1)    Licenses

The Company’s intangible assets represent in-licenses of development-phase compounds acquired by the Company, where the Company continues or has the option to continue to do the development work (“R&D assets”), as well as commercialization rights for approved products ("Commercialization assets") which were fully derecognized in 2023 as part of the sale of the rights to Movantik® asset (See also note 15(6)).

R&D assets that are available for use are stated at cost and amortized on a straight-line basis over their useful life from the time they are available for use. R&D assets that are not available for use are not amortized and are tested for impairment at least annually.

Amounts due for future payments based on contractual agreements are accrued upon reaching the relevant milestones.

All intangible assets are tested for impairment if any events have occurred or changes in circumstances have taken place which might indicate that their carrying amounts may not be recoverable. See also note 3 for key assumptions used in the determination of the recoverable amounts.

2)    Research and development

Research expenses are recognized as an expense as incurred.

Research and development costs for the performance of pre-clinical trials, clinical trials, and    manufacturing by subcontractors are recognized as expenses when incurred.

g.     Financial liabilities

Non-derivative financial liabilities are initially recognized at their fair value minus transaction costs and are subsequently measured at amortized cost. In case there is a difference between the fair value at initial recognition and the transaction price (“day 1 loss”), the financial liabilities are adjusted to reflect the day 1 loss and changes are recorded to profit or loss while unrecognized day 1 loss is amortized over the contractual life of the instrument. Any amounts not recognized in profit or loss before the date of exercise or maturity will be recognized in profit or loss on that date.

Warrants exercisable to the Company’s ordinary shares are classified as an equity instrument only if the warrants are settled by the Company exchanging a fixed amount of cash for a fixed number of its own equity instruments (the ‘fixed for fixed’ criteria). Otherwise, the warrants are classified as a derivative financial liability measured at fair value through profit or loss.

Transaction costs relating to the issuance of derivative financial liabilities measured at fair value through profit or loss are expensed to profit or loss.

Financial liabilities are included in current liabilities, except for those with maturities greater than 12 months after the Statements of Financial Position date (for which they are classified as noncurrent liabilities).

Financial liabilities are derecognized when, and only when, they are extinguished. The difference between the carrying amount of the financial liability extinguished and the consideration paid, including any non-cash assets transferred, is recognized in profit or loss. As for the accounting for the extinguishment of the financial liability to HCR, as well as the Global Termination Agreement which terminated all remaining credit ties related to this transaction, see note 15(6).  

h.   Share-based payments.

The Company operates several equity-settled, share-based compensation plans to employees and service providers. As part of the plans, the Company grants employees and service providers, from time to time and at its discretion, options to purchase Company shares. For employees, the total amount recognized as an expense over the vesting period of the options is determined by reference to the fair value of the options at the grant date. For service providers, the Company measures the awards based on the fair value of the asset or service received. The amounts are recorded against the accumulated deficit within equity.

Vesting conditions (other than market conditions) are included in the assumptions about the number of options that are expected to vest.

At the end of each reporting period, the Company revises its estimates of the number of options that are expected to vest based on non-market vesting conditions. The Company recognizes the impact of the revision to original estimates, if any, in profit or loss, with a corresponding adjustment to accumulated deficit.

When exercising options, the Company issues new shares. The proceeds, less directly attributable transaction costs, are recognized as share capital (par value) and additional paid-in capital. 

i.    Revenue from contracts with customers

The Company generated revenue in the years presented in these financial statements mainly from product sales, including in-licensed products.

1)    Revenue from the sale of products

The Company sells products mainly to wholesale distributors. Revenue is recognized at a point in time when control over the product is transferred to the customer (upon delivery), at the net selling price, which reflects reserves for variable consideration, including discounts and allowances.

The Company estimates variable consideration and includes it in the transaction price only to the extent it is highly probable that a significant reversal of cumulative revenue recognized will not occur when the uncertainty associated with the variable consideration is subsequently resolved.

The specific considerations the Company uses in estimating these amounts related to variable consideration are as follows:

Trade discounts and distribution fees - The Company offers discounts to its customers, as an incentive for prompt payment. The Company records these discounts as a reduction of revenue in the period the related revenue from the sale of products is recognized. In addition, distribution fees are paid to certain distributors based on contractually determined rates from the gross consideration. As the fee paid to the customer is not for a distinct good or service, it is recognized as a reduction of revenue in the period the related revenue from the sale of products is recognized.

Rebates and patient discount programs - The Company offers various rebate and patient discount programs, which result in discounted prescriptions to qualified patients. The Company estimates the allowance for these rebates and coupons based on historical and estimated utilization of the rebate and discount programs, at the time the revenues are recognized. These estimates are recognized as a reduction of revenue. See also notes 3 and 13.

Product returns - The Company offers customers a right of return of expired products. The Company estimates the amount of product sales that may be returned by its customers and records this estimate as a reduction of revenue at the time of sale, based on historical rates of return, or, if such historical data is not available, the Company estimates product returns based on its own sales information, its visibility into the inventory remaining in the distribution channel and product dating.

2) Practical expedients and exemptions

The Company expenses sales commissions when incurred since the amortization period of the asset that the Company otherwise would have recognized would have been for less than one year. These costs are recorded as selling and marketing expenses. 

3)    Revenues from licensing

Licenses of intellectual property (“IP”) rights are distinct from other promises in a contract with a customer (such as manufacturing and supply services) if the customer can benefit from the IP either on its own or together with other resources that are readily available to the customer and if the Company’s promise to license the IP is separately identifiable from other promises in the contract.  

If the promise to grant the license is distinct, the Company determines whether the nature of the promise in granting the license is to provide the customer with either a right to access the Company’s IP as it exists throughout the license period or a right to use the Company’s IP as it exists at the point in time at which the license is granted. Accordingly, revenue from a license providing a right of use to the Company’s IP is recognized at the point in time when control of the distinct license is transferred to the customer.

Sales -based royalties that are allocated to license of IP are recognized only when (or as) the later of the following occurs: (a) the subsequent sale occurs; and (b) the performance obligation to which some or all the sales-based royalty has been allocated has been satisfied (or partially satisfied).

The Company applies a practical expedient in the standard and does not adjust the transaction price for the effects of significant financing components if, at contract inception, the Company expects the period between customer payment and the transfer of goods or services to be one year or less.

Revenue from achieving additional milestones is recognized only when it is highly probable that a significant reversal of cumulative revenues will not occur, usually upon achievement of the specific milestone, in accordance with the relevant agreement.

   

j.    Earnings (Loss) per share

The computation of basic earnings (loss) per share is based on the Company’s earnings (loss) divided by the weighted average number of ordinary shares and pre-funded warrants outstanding during the period.

In calculating the diluted earnings (loss) per share, using the treasury stock method, the Company adds the weighted average of the number of shares to be issued to the average number of shares outstanding including pre-funded warrants used to calculate the basic earnings (loss) per share, assuming all shares that have a potentially dilutive effect have been exercised into shares. 

k.    Deferred taxes

Since the Company is unable to assess whether it will have taxable income in the foreseeable future, no deferred tax assets were recorded in these financial statements. 

 

l.    Leases

The leases are recognized as a right-of-use asset and a corresponding liability at the date at which the leased asset is available for use by the Company. Each lease payment is allocated between the liability and finance cost. The finance cost is charged to profit or loss over the lease period so as to produce a constant periodic rate of interest on the remaining balance of the liability for each period.

The right-of-use asset is depreciated over the shorter of the asset’s useful life and the lease term on a straight-line basis.

Assets and liabilities arising from a lease are initially measured on a present value basis. Lease liabilities include the net present value of fixed lease payments and variable lease payments that are based on an index or a rate.

The lease payments are discounted using the lessee’s incremental borrowing rate, as the interest rate implicit in the lease is not readily determined.

Right-of-use assets are measured at cost being the amount of the initial measurement of the lease liability.

Payments associated with short-term leases and leases of low-value assets are not recognized as right-of-use assets or lease liabilities but are recognized on a straight-line basis as an expense in profit or loss. Short-term leases are leases with a lease term of 12 months or less. Low-value assets include IT-equipment and small items of office furniture.

Contracts may contain both lease and non-lease components. For leases of properties, the Company allocates the consideration in the contract to the lease and non-lease components based on their relative stand-alone prices. However, for leases of vehicles, the Company has elected not to separate lease and non-lease components and instead accounts for these as a single lease component.

m.    New international financial reporting standards, amendments to standards and new interpretations:

1)Classification of Liabilities as Current or Non-Current (Amendment to IAS 1)

The narrow-scope amendments to IAS 1, “Presentation of Financial Statements,” clarify that liabilities are classified as either current or noncurrent, depending on the rights that exist at the end of the reporting period. Classification is unaffected by the entity’s expectations or events after the reporting date. The amendments also clarify what IAS 1 means when it refers to the settlement’ of a liability. The amendments may affect the classification of liabilities, particularly for entities that previously considered management’s intentions to determine classification and for some liabilities that can be converted into equity. The Company adopted these amendments effective January 1, 2024. The impact on the Company’s financial statements of these amendments was the reclassification of the Company’s derivative financial instruments from non-current to current as of its effective date, as the Company does not have the right to defer settlement of liability for at least twelve months after the reporting period. The Company has retrospectively applied the amendments in these interim financial statements and, accordingly, has retrospectively adjusted the comparative balance sheet for December 31, 2023, to reclassify its warrant liabilities ($741 as of December 31, 2023) from non-current to current. Adoption of the amendments had no other impact on the Company’s financial statements.

2)In its July 2024 Board meeting, the IASB approved an IFRIC agenda decision on ‘Disclosure of Revenues and Expenses for Reportable Segments (IFRS 8 Operating Segments)’. IFRS 8 Operating Segments requires an entity to disclose specific information about assets, liabilities and profit or loss by segment. Specifically, IFRS 8 paragraph 23 requires an entity to disclose certain specified items of profit or loss if these are included in the measure of segment profit or loss reviewed by the chief operating decision maker or are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. Management of the Company has implemented the agenda decision in these December 2024 annual financial statements (see note 24).
3)IFRS 18, Presentation and Disclosure in the Financial Statements

This standard replaces the international accounting standard IAS 1, “Presentation of Financial Statements.” As part of the new disclosure requirements, companies will be required to present new defined subtotals in the statements of income, as follows: (1) operating profit and (2) profit before financing and tax. In addition, income statement items will be classified into three defined categories: operating, investment and financing. The standard also includes a requirement to provide a separate disclosure in the financial statements regarding the use of management-defined performance measures (“non-GAAP measures”), and specific instructions were added for the grouping and splitting of items in the financial statements and in the notes to the financial statements. IFRS 18 is effective for annual reporting periods beginning on or after January 1, 2027, with an option for early adoption.

v3.25.1
CRITICAL ACCOUNTING ESTIMATES AND JUDGMENTS
12 Months Ended
Dec. 31, 2024
CRITICAL ACCOUNTING ESTIMATES AND JUDGMENTS  
CRITICAL ACCOUNTING ESTIMATES AND JUDGMENTS

NOTE 3 - CRITICAL ACCOUNTING ESTIMATES AND JUDGMENTS:

The preparation of financial statements requires management to make estimates which, by definition, will seldom equal the actual results and will affect the reported amounts in the Company’s consolidated financial statements and the accompanying notes. Some of the policies described in note 2 of the Company’s consolidated financial statements involve a high degree of judgment or complexity. The Company believes that the most critical accounting policies and significant areas of judgment and estimation are in:

Recognition and measurement of allowance for rebates and patient discount programs.

Impairment reviews of intangible research and development assets.

Recognition and measurement of allowance for rebates and patient discount programs

The Company offers various rebate and patient discount programs, which result in discounted prescriptions to qualified patients. These rebates and discounts, provided to wholesalers and patients, are accounted for as variable consideration, and recognized as a reduction in revenue, for which unsettled amounts are accrued. Rebate allowances are calculated based on historical and estimated utilization at revenue recognition.  

The main estimates used in recognizing and measuring these allowances relate to the amount of products sold to customers not yet prescribed to patients (units “in the channel”) and the projected duration of selling these units. The Company periodically evaluates its estimates against actual results and, if necessary, updates the estimates accordingly.

Impairment reviews of intangible R&D assets

The Company reviews annually or when events or changes in circumstances indicate the carrying value of the R&D assets may not be recoverable.

When and if necessary, an impairment loss is recognized for the amount by which the asset’s carrying amount exceeds its recoverable amount. The recoverable amount is determined using discounted cash flow calculations where the asset’s expected post-tax cash flows are risk-adjusted over their estimated remaining useful economic life. The risk-adjusted cash flows are discounted using the estimated Company’s post-tax weighted average cost of capital (“WACC”) which is 18.1%.

The main estimates used in calculating the recoverable amount include: outcome of the therapeutic candidates' R&D activities; probability of success in gaining regulatory approval, size of the potential market and the Company’s asset’s specific share in it; amount and timing of projected future cash flows and the Company’s main interest rate risk during the periods.

In the years presented in these financial statements, there were no impairments recorded for intangible R&D assets.

v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT
12 Months Ended
Dec. 31, 2024
FINANCIAL INSTRUMENTS  
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT

NOTE 4 - FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT:

a.Financial risk management:

1)    Financial risk factors

The Company’s faces various financial risks: market risks (including foreign exchange and interest risks), credit risk and liquidity risk. The Company’s overall risk management program focuses on the unpredictability of financial markets and seeks to minimize potential adverse effects on the Company’s results of operations and financial position.

Risk management is performed by the Chief Financial Officer of the Company who identifies and evaluates financial risks in close cooperation with the Company’s Chief Executive Officer.

The Company’s finance department is responsible for carrying out financial risk management activities in accordance with policies approved by its BoD. The BoD provides general guidelines for overall financial risk management, as well as policies dealing with specific areas, such as exchange rate risk, interest rate risk, credit risk, use of financial instruments, and investment of excess cash. In order to minimize market risk and credit risk, the Company invests the majority of its cash balances in low-risk investments, such as highly rated bank deposits with terms of up to one-year term with exit points.

(a)   Market risks

The Company may face foreign exchange risk due to payments and investments in currencies other than the U.S. dollar, its functional currency. The Company manages the foreign exchange risk by aligning its liquidity currencies with the currencies of expected expenses, based on projected cash flows. A 5% appreciation of the U.S. dollar against the NIS, assuming all other variables remained constant, would have resulted in a negligible change in expenses across all the reported years, indicating immaterial foreign exchange risks.

(b)  Credit risk

Credit risk arises mainly from cash and cash equivalents, bank deposits, restricted cash, and trade receivables. The Company estimates that since the liquid instruments are mainly invested with highly rated institutions, the credit and interest risks associated with these balances are low.

Credit risk from trade receivables involves the potential non-payment by customers. The Company manages this risk by setting credit limits, performing controls and monitoring qualitative and quantitative indicators of trade receivable balances such as the period of credit taken and overdue payments. Customer credit risk also arises due to revenue concentration among major customers. The Company primarily sells to three major U.S. wholesalers with virtually no historical losses. Considering this and forward-looking customer analyses, no loss allowance for trade receivables was recorded as of December 31, 2024, and December 31, 2023. See also note 24(b).

(c)   Liquidity risk

Prudent liquidity risk management requires maintaining sufficient cash or the availability of funding through an adequate amount of committed credit facilities. Management monitors rolling forecasts of the Company’s liquidity reserve (comprising of cash and cash equivalents and deposits). This is generally carried out based on the expected cash flow in accordance with practices and limits set by the management of the Company.

As of December 31, 2024, the Company has generated revenues from commercialization activities. However, as further described in note 1, no sufficient revenue was generated to compensate for operating expenses. leading to liquidity risks and raising significant doubt about its ability to continue as a going concern.

The tables below break down the Company’s financial liabilities into relevant maturity groupings based on their contractual and estimated maturities. The amounts disclosed in the tables are the contractual and estimated undiscounted cash flows.

Contractual maturities of financial liabilities
As of  December 31, 2024

Less than 1 year

2-5 years

More than 5 years

Total contractual cash flows

Carrying amount

U.S. Dollars in Thousands

Account payable

1,168

1,168

1,168

Lease liabilities

365

3

368

356

Accrued expenses and other current liabilities

9,993

9,993

9,993

Royalty obligation

137

1,246

1,383

500

Total

11,526

140

1,246

12,912

12,018

Contractual maturities of financial liabilities
As of  December 31, 2023

Less than 1 year

2-5 years

More than 5 years

Total contractual cash flows

Carrying amount

U.S. Dollars in Thousands

Accounts payable

3,278

3,278

3,278

Lease liabilities

766

475

1,241

1,173

Accrued expenses and other current liabilities

4,592

4,592

4,592

Royalty obligation

282

1,553

1,835

540

Total

8,636

757

1,553

10,946

9,583

2)    Capital risk management

The Company’s objectives when managing capital are to safeguard the Company’s ability to continue as a going concern in order to provide returns for shareholders, maintain optimal capital structure, and to reduce the cost of capital.

3)    Fair value estimation

The carrying amount of cash equivalents, restricted cash, bank deposits, receivables, account payables and accrued expenses approximate their fair value due to their short-term characteristics.

The fair value of the Royalty obligation balance is not materially different from its carrying amount.

The following table presents the change in derivative liabilities measured at level 3 for the year ended December 31, 2024, and December 31, 2023:

Derivative financial instruments

Year Ended December 31, 

    

    

2024

    

2023

 

U.S. dollars in thousands

Balance at beginning of the period

741

2,623

Initial recognition of financial liability

9,860

10,932

Initial recognition of unrecognized day 1 loss

(952)

Exercise of financial liability  

(18,383)

Fair value adjustments and recognition of day 1 loss recognized in profit or loss

(8,228)

5,569

Balance at end of the period

1,421

741

As of December 31, 2024, the unrecognized day 1 loss is $0.8 million.

See also notes 17(b) - 17 (f) and 17(i)-17(j).

Financial Instruments:

U.S. dollars in thousands

Non-cash changes

January 1, 2024

Principal and interest payments (includes credits)

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2024

Payables in respect to the global termination agreement (See note 15(6)(b))

11,443

(4,750)

6,693

Lease liabilities

1,173

(691)

(188)

55

7

356

Non-cash changes

January 1, 2023

Principal and interest payments

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2023

Borrowing

115,216

(115,216)

Payable in respect of intangible assets purchase

11,157

(6,555)

(4,602)

Lease liabilities

7,475

(1,529)

270

(5,413)

367

3

1,173

Non-cash changes

January 1, 2022

Principal and interest payments

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2022

Borrowing

83,620

(7,507)

39,103

115,216

Payable in respect of intangible assets purchase

20,480

(11,123)

1,800

11,157

Lease liabilities

4,192

(2,010)

5,003

430

(140)

7,475

v3.25.1
CASH AND CASH EQUIVALENTS
12 Months Ended
Dec. 31, 2024
CASH AND CASH EQUIVALENTS.  
CASH AND CASH EQUIVALENTS

NOTE 5 - CASH AND CASH EQUIVALENTS:

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Cash in bank

1,882

5,569

Short-term bank deposits

 

2,735

 

-

 

4,617

 

5,569

The carrying amounts of the cash and cash equivalents approximate their fair values.

v3.25.1
PREPAID EXPENSES AND OTHER RECEIVABLES
12 Months Ended
Dec. 31, 2024
PREPAID EXPENSES AND OTHER RECEIVABLES  
PREPAID EXPENSES AND OTHER RECEIVABLES

NOTE 6 - PREPAID EXPENSES AND OTHER RECEIVABLES:

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Advance to suppliers

77

1,310

Government institutions

 

334

 

694

Prepaid expenses and others

 

693

 

797

 

1,104

 

2,801

The fair value of other receivables which constitute financial assets approximate their carrying amount.

v3.25.1
INVENTORY
12 Months Ended
Dec. 31, 2024
INVENTORY  
INVENTORY

NOTE 7 - INVENTORY:

December 31,

    

2024

    

2023

 U.S. dollars in thousands

Raw materials

513

828

Work in progress

308

233

Finished goods

 

2,830

 

3,328

 

3,651

 

4,389

During the years ended December 31, 2024, 2023, and 2022, the Company recognized amounts of $3.4 million, $4.4 million, and $9.7 million respectively, in inventory cost as part of cost of revenues.

The amounts recognized include write-downs of inventories to net realizable value amounted to $0.2 million in 2024, $1.3 million in 2023, and $2.4 million in 2022. These were recognized as an expense, included in cost of revenues in the Consolidated Statements of Comprehensive Income (Loss).

v3.25.1
FIXED ASSETS
12 Months Ended
Dec. 31, 2024
FIXED ASSETS  
FIXED ASSETS

NOTE 8 - FIXED ASSETS:

The composition of assets and accumulated depreciation are grouped by major classifications:

Cost

Accumulated depreciation

Depreciated balance

December 31

December 31

December 31

    

2024

    

2023

    

2024

    

2023

    

2024

    

2023

U.S. dollars in thousands

Office furniture and equipment (including computers)

 

1,068

 

1,059

 

988

 

956

 

80

 

103

Leasehold improvements

 

379

 

379

 

324

 

289

 

55

 

90

 

1,447

 

1,438

 

1,312

 

1,245

 

135

 

193

v3.25.1
LEASES
12 Months Ended
Dec. 31, 2024
LEASES  
LEASES

NOTE 9 - LEASES:

Amounts recognized in the consolidated statements of financial position:

December 31,

    

2024

    

2023

U.S dollars in thousands

Right-of-use assets:

Properties

302

 

773

Vehicles

 

216

302

 

989

Lease liabilities:

  

 

  

Current

353

718

Non-current

3

 

455

356

 

1,173

For the year ended December 31, 2023, there were additions of $0.3 million. Decrease in lease liability during the year ended December 31, 2024, and 2023, were $0.2 million and $5.4 million respectively (with corresponding decrease in right of use asset in an amount of $0.2 million and $4.7 million respectively) resulting from early terminations of leases in 2024 and 2023.

In June 2023, the company terminated a U.S. office lease signed in March 2022 resulting in a $0.7 million gain. The termination, part of ongoing cost reduction efforts, followed a decrease in headcount, that reduced the Company's need for the office lease.

Amounts recognized in the consolidated statements of comprehensive loss:

Year Ended December 31,

    

2024

    

2023

Depreciation charge of right-of-use assets

Properties

470

 

798

Vehicles

51

478

521

1,276

Interest expense

55

367

Foreign exchange differences

7

3

Expenses relating to short-term leases and leases of low-value assets are immaterial.

The total cash outflow for leases in 2024 and 2023 was $0.7 million and $1.5 million respectively.

v3.25.1
INTANGIBLE ASSETS
12 Months Ended
Dec. 31, 2024
INTANGIBLE ASSETS  
INTANGIBLE ASSETS

NOTE 10 - INTANGIBLE ASSETS:

a.    The Company’s intangible assets represent in-licenses of R&D assets. The changes in those assets are as follows:

 

Year Ended December 31, 

 

2024

    

2023

 

U.S. dollars in thousands

  

  

R&D assets:

Cost:

Balance at beginning of year

5,757

5,757

Balance at end of year

5,757

5,757

Accumulated amortization:

Balance at beginning of year

(179)

(148)

Amortization charges

(31)

(31)

Balance at end of year

(210)

(179)

5,547

5,578

Commercialization assets:

Cost:

Balance at beginning of year

11,788

89,373

Disposal during the year

(11,788)

(77,585)

Balance at end of year

11,788

Accumulated impairments and amortization:

Balance at beginning of year

(11,788)

(29,356)

Amortization and impairment charges

(514)

Disposal during the year

11,788

18,082

Balance at end of year

(11,788)

5,547

5,578

The Company estimated the useful life of the assets related to Talicia® at approximately 15 years from marketing approval date November 2019. The amortization expenses are recognized under Cost of Revenues in the Consolidated Statements of Comprehensive Income (Loss).

See also note 15 (6) regarding the transfer of the Company’s rights in Movantik® to HCRM in exchange for all the Company’s debt obligations under the Credit Agreement with HCRM.

In July 2024, the Company terminated its license agreement with Cosmo Technologies Ltd. (“Cosmo”) for Aemcolo® (see note 15(9)), effective October 8, 2024. Following the termination,  the Company derecognized the remaining carrying amounts related to the Aemcolo® intangible asset, including its cost and accumulated amortization and impairment. As the asset had been fully written off as of December 31, 2022, the derecognition had no effect on the Consolidated Statements of Financial Position or Consolidated Statements of Comprehensive Income (Loss).

v3.25.1
LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT
12 Months Ended
Dec. 31, 2024
LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT  
LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT

NOTE 11 - LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT:

The Company’s pension liability and the Company’s liability for payment of severance pay for employees in Israel for whom the liability is within the scope of Section 14 of the Severance Pay Law, is covered by ongoing deposits with defined contribution plans. The amounts deposited are not included in the Statements of Financial Position.

The amounts charged as an expense with respect to defined contribution plans in 2024, 2023, and 2022 were $156,000, $206,000, and $261,000, respectively.

v3.25.1
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES
12 Months Ended
Dec. 31, 2024
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES  
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES

NOTE 12- ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES:

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Accrued expenses

 

2,698

 

3,765

Payable in respect to the Global Termination Agreement (see note 15(6)(b))

6,693

-

Employees and related liabilities

 

510

 

727

Government institutions

 

92

 

100

 

9,993

 

4,592

v3.25.1
ALLOWANCE FOR DEDUCTIONS FROM REVENUES
12 Months Ended
Dec. 31, 2024
ALLOWANCE FOR DEDUCTIONS FROM REVENUES  
ALLOWANCE FOR DEDUCTIONS FROM REVENUES

NOTE 13 - ALLOWANCE FOR DEDUCTIONS FROM REVENUES:

The following table shows the movement of the allowance for deductions from revenue:

    

Rebates and patient discount programs

    

Product returns

    

Total

U.S. dollars in thousands

As of January 1, 2024

 

8,087

 

2,567

10,654

Increases

9,712

259

9,971

Decreases (utilized)

 

(10,423)

(2,500)

(12,923)

Adjustments

487

1,099

1,586

As of December 31, 2024

 

7,863

 

1,425

9,288

Rebates and patient discount programs

Product returns

Total

    

U.S. dollars in thousands

As of January 1, 2023

 

46,636

 

1,234

47,870

Increases

21,225

859

22,084

Decreases (utilized)

 

(60,498)

(2,969)

(63,467)

Adjustments

724

3,443

4,167

As of December 31, 2023

 

8,087

 

2,567

10,654

Rebates and patient discount programs

Product returns

Total

U.S. dollars in thousands

As of January 1, 2022

 

29,742

 

969

30,711

Increases

123,878

2,547

126,425

Decreases (utilized)

 

(108,531)

(2,192)

(110,723)

Adjustments

1,547

(90)

1,457

As of December 31, 2022

 

46,636

1,234

47,870

v3.25.1
BORROWING
12 Months Ended
Dec. 31, 2024
BORROWING.  
BORROWING

NOTE 14 – BORROWING:

 Credit agreement with HCRM

On February 23, 2020 (“Closing Date”), RedHill Inc. entered into a credit agreement and certain security documents (the “Credit Agreement”) with HCRM.

The Credit Agreement contained certain customary affirmative and negative covenants, including a financial covenant requiring RedHill Inc. to maintain a minimum level of cash, as well as a covenant requiring it to maintain minimum net sales. In 2022, the Company did not maintain certain covenants in the Credit Agreement. Subsequently, on February 2, 2023, the Company and RedHill Inc. reached an agreement with HCRM resulting in the extinguishment of all of RedHill Inc. debt obligations (including all principal, interest, revenue interest, prepayment premiums and exit fees) under the Credit Agreement in exchange for the transfer of its rights in Movantik® to Movantik Acquisition Co., an affiliate of HCRM. On July 15, 2024, the Company and RedHill Inc signed a Global Termination Agreement with Movantik Acquisition Co., Valinor Pharma, LLC, and HCR Redhill SPV, LLC, affiliates of HCRM. This agreement terminates the Credit Agreement from February 23, 2020, which was amended on February 2, 2023. See also note 15(6).

As described above, the Credit Agreement contained a financial covenant requiring the Company to maintain a level of cash liquidity, on any business day from the Closing Date to the maturity date, in accounts that are subject to HCRM’s control. Therefore, the amounts of minimum cash and cash equivalents are excluded from cash and cash equivalents in the Statements of Cash Flows for the relevant periods. Instead, the movements in this restricted cash are presented as financing activities in the Statements of Cash Flows. See also note 15(6).

v3.25.1
COMMITMENTS
12 Months Ended
Dec. 31, 2024
COMMITMENTS  
COMMITMENTS

NOTE 15 - COMMITMENTS:

Agreements to purchase intellectual property and commercial products:

1)   On August 11, 2010, the Company acquired intellectual property for three gastrointestinal therapeutic candidates through an asset purchase agreement with a publicly-traded Australian company. Pursuant to the asset purchase agreement, as amended, the Company paid the Australian company an initial amount of $500,000 and undertook to pay future payments in the range of 7% - 20% from the Company’s revenues that may be generated from the sale and sublicense of the therapeutic candidates, less certain deductible amounts, as detailed in the agreement. Such potential payments are due until termination or expiration of the last of the patents transferred to the Company pursuant to the agreement (each on a product-by-product basis).  

Through December 31, 2024, the Company has paid the Australian company in total $1.5 million.

2)   On June 30, 2014, the Company entered into an agreement with a German company that granted the Company the exclusive worldwide (excluding China, Hong Kong, Taiwan, and Macao) development and commercialization rights to all indications to a therapeutic candidate. Under the terms of the agreement, the Company paid the German company an upfront payment of $1 million and agreed to pay the German company potential tiered royalties, less certain deductible amounts, as detailed in the agreement, ranging from mid-teens and up to 30%. Such potential royalties are due until the later of (i) the expiration of the last to expire licensed patent that covers the product in the relevant country and (ii) the expiration of regulatory exclusivity in the relevant country. Through December 31, 2024, the Company has paid the German company only the initial amount mentioned above.

3)   On March 30, 2015, the Company entered into an agreement with a U.S.-based private company that granted the Company the exclusive worldwide development and commercialization rights for all indications to a therapeutic candidate, and additional intellectual property rights, targeting multiple oncology, inflammatory and GI indications. Under the terms of the agreement, the Company undertook to pay the U.S. company an initial amount of $1.5 million and an additional amount of $2 million to be paid on a specific date. In addition, the Company undertook to pay up to $2 million in potential development milestone payments, and potential tiered royalties on revenues, less certain deductible amounts starting in the low double-digits, as detailed in the agreement. Such potential royalties are due until the later of (i) the expiration of the last to expire licensed patent that covers the product in the relevant country; and (ii) the expiration of regulatory exclusivity in the relevant country. Through December 31, 2024, the Company paid the U.S. company a total of $3 million.

Following an amendment to the agreement from February 2018, during December 2018, the Company elected to convert the remaining $0.5 million into increased future potential royalty payments. The liability is adjusted based on the Company's expectations for future royalty payments.  As of December 31, 2024, and December 31, 2023, the Company recognized $0.50 million and $0.54 million, respectively, as a non-current liability for the potential royalty payments.

4)   Movantik® acquisition:

Effective April 1, 2020 (the (“Effective Date”), RedHill Inc. entered into an exclusive license agreement with AstraZeneca, granting RedHill Inc. exclusive, worldwide (excluding Europe, Canada) commercialization and development rights to Movantik® (naloxegol).

The total acquisition consideration, including upfront payment, discounted present value of the deferred payment amounted to approximately $65 million amortized over 12.5 years from the effective date.

See also note 15 (6) regarding the transfer of the Company’s rights in Movantik® to HCRM in exchange for all the Company’s debt obligations under the Credit Agreement with HCRM.

5)     As part of the Movantik® acquisition, RedHill Inc. assumed an existing co-commercialization agreement with DSI. Effective July 1, 2020, this agreement was replaced with a new agreement, under which RedHill Inc. committed to payments totaling $15.1 million, of which $10.1 million paid during 2022, and the remaining of $5 million was assumed by HCRM under the agreement described in note 15(6)(a).

6) Movantik Transactions:

a)On February 2, 2023, the Company and RedHill Inc. reached an agreement with HCRM resulting in the extinguishment of all of RedHill Inc. debt obligations (including all principal, interest, revenue interest, prepayment premiums and exit fees) under the Credit Agreement in exchange for the transfer of its rights in Movantik® to Movantik Acquisition Co., an affiliate of HCRM. HCRM assumed substantially all post-closing liabilities, and RedHill Inc. retained substantially all pre-closing liabilities relating to Movantik®. As part of the parties' arrangement, and to ensure continuous patient care, RedHill Inc. also provided nine months of paid transition services. HCRM retained security interests in certain of the Company’s assets until substantially all pre-closing liabilities of Movantik® have been paid or other specific conditions are met. Following the agreement, the $16 million held as restricted cash under the Credit Agreement was deposited into an escrow account to pay pre-closing liabilities of Movantik®. As of December 31, 2023, the amount held in the escrow account was $0.8 million.

Accounting treatment:

Prior to the sale of Movantik®, the Company presented the rights to Movantik® as an intangible asset in its consolidated statement of financial position (classified under the non-current assets).

In addition, due to the condition described in note 14(a), at the sale date, the carrying amount of the borrowing from HCRM reflected all amounts owing or payable under the Credit Agreement as being immediately due (classified under the current liabilities).

The gains from transferring Movantik® rights and extinguishment of debt obligations include: (1) the gain from the sale of Movantik®, reflecting the difference between the carrying value and fair value of the assets transferred, presented as other income in the amount of $35.5 million and (2) the gain from the debt extinguishment, reflecting the difference between the carrying amount (the amortized cost) of the financial liability to HCRM and the fair value of the assets transferred, presented as financial income in the amount of $20.6 million.

To determine the fair value of the rights to Movantik®, the Company based its estimate on the terms outlined in a non-binding term sheet with a third party which ultimately did not materialize, which included a cash payment of $95 million for the rights to Movantik®.

The fair value of nonmonetary assets relating to Movantik® transferred to settle debt obligations was used to measure debt extinguishment gain. The service fees relating to the transition services are presented in the Company’s consolidated statement of comprehensive income (loss) as other income.

b)On July 15, 2024, the Company and RedHill Inc signed a Global Termination Agreement with Movantik Acquisition Co., Valinor Pharma, LLC, and HCR Redhill SPV, LLC, affiliates of HCRM (the “Global Termination Agreement”). This agreement terminates the Credit Agreement dated February 23, 2020, as amended on February 2, 2023, which included a lien on Talicia® and Aemcolo® assets and established an escrow account with restricted funds for Movantik® liabilities (for further details, see note 1(a)(2) above and notes 14(a), 15(4), 15(5), and 15(6)(a)).

The Global Termination Agreement terminated all existing credit ties, removing the aforementioned lien and restoring control over the restricted escrow funds and settlement of trade balances resulting from the transition services. In connection with the agreement, the Company received approximately $9.9 million in cash for the settlement of liabilities related to Movantik®, that were allocatable to HCRM and its affiliates under their agreements with the Company. As the cash received was less than the total net amount of these liabilities (approximately $12.2 million), the Company recognized a loss of approximately $2.3 million resulting from the termination agreement, presented under other expenses in the Consolidated Statements of Comprehensive Income (Loss). In addition, the Company gained full control over $0.7 million previously held in the restricted account.

7)   

In October 2021, the Company entered into a license agreement with Gaelan Medical Trade LLC ("Gaelan") for Talicia® in the United Arab Emirates (UAE). The Company received a $2 million upfront payment in April 2022 and is eligible for additional milestone payments and tiered royalties up to mid-teens on net sales of Talicia® in the UAE. Gaelan is responsible for obtaining and maintaining regulatory approvals, and any and required clinical or other studies. In March 2022, the agreement was amended to allow Gaelan to sublicense or assign its rights and obligations.

A related supply agreement designates the Company (via a third party CMO) as exclusive manufacturer and supplier of Talicia® to Gaelan during the term of the agreement.

The Company accounted for the license and manufacturing and supply services as distinct performance obligations, mainly due to the manufacturing not being specialized or unique and can be manufactured by others (i.e. – the good or service is capable of being distinct), as well as due to that the license agreement and the manufacturing and supply services do not significantly affect each other (i.e. – the promise is distinct within the context of the contract). During 2022, the Company provided Gaelan substantially all the documentation which represents the right to use the licensed IP, as well as the paperwork relating to the IP itself and its regulatory documents. Accordingly, and since the manufacturing services are priced at their standalone selling price, the Company recognized the $2 million upfront consideration as revenues in the Consolidated Statements of Comprehensive Income (Loss) for the year ended 2022. In August 2024, Gaelan made its first commercial sale in the UAE, triggering a $0.5 million milestone payment due in August 2025. The Company recognized this milestone as revenue in the Consolidated Statements of Comprehensive Income (Loss) for the year ended 2024, along with royalty revenues from sales made during the year (see also Note 19).

8)   In March 2022, the Company entered into an exclusive license agreement with Kukbo Co. Ltd ("Kukbo") for oral opaganib for the treatment of COVID-19 in South Korea,. Under the terms of the license agreement, the Company is entitled to an upfront payment of $1.5 million as well as milestone payments and royalties on net sales. Kukbo is entitled under the agreement to the exclusive rights to opaganib in South Korea for COVID-19.

Following Kukbo’s default in paying the Company $5 million under a subscription agreement, dated October 25, 2021, in exchange for ADSs, and of the $1.5 million due under the license agreement as described above, the Company filed a lawsuit in NYC against Kukbo in September 2022. Kukbo subsequently filed claims against RedHill.

     

In December 2024, the court granted summary judgment in the Company’s favor, awarding approximately $6.5 million in principal, plus accrued interest at a rate of 9% per annum- amounting to approximately $1.8 million as of December 31, 2024. The court also ruled that the Company is entitled to recover its attorneys’ fees, which based on RedHill’s records totaled approximately $1.8 million as of December 31, 2024. Kukbo’s counterclaims were dismissed in full. Kukbo filed a notice of appeal and retains the right to seek an appeal. As of December 31, 2024, the Company had not recognized any revenue under the license agreement as the criteria for revenue recognition were not yet met.

The Company is party to a contingency fee agreement with its legal firm, Haynes and Boone, LLP, as amended on December 29, 2024. Under the agreement, the firm is entitled to a double-digit percentage of the gross amount recovered if the case results in a final favorable outcome, not subject to further appeal. If no collection is made within six months of such an outcome, the Company must pay the firm its standard hourly fees incurred since entering into the agreement (approximately $1.1 million as of December 31, 2024). If a recovery is later collected, the Company must pay the balance up to the full contingency-based amount. As the case remains ongoing and has not yet reached a final favorable outcome, the legal fees incurred since entering into the agreement have not been recognized as expenses, as no payment is due unless the Company prevails.

9)   In July 2024, the Company terminated its license agreement with Cosmo for Aemcolo®, a treatment for traveler’s diarrhea. The agreement, initially dated October 17, 2019, was officially terminated on October 8, 2024. Upon termination, the Company ceased all commercialization of Aemcolo® and all rights under the agreement reverted to Cosmo.

v3.25.1
INCOME TAX
12 Months Ended
Dec. 31, 2024
INCOME TAX  
INCOME TAX

NOTE 16 - INCOME TAX:

a.   Taxation of the Company in Israel:

1)   Measurement of results for tax purposes

The Company elected to compute its taxable income in accordance with Income Tax Regulations (Rules for Accounting for Foreign Investors Companies and Certain Partnerships and Setting their Taxable Income), 1986. Accordingly, the Company’s taxable income or loss is calculated in U.S. dollars.

The results of the Company are measured for tax purposes in accordance with Accounting Principles Generally Accepted in Israel (Israeli GAAP). These financial statements are prepared in accordance with IFRS. The differences between IFRS and Israeli GAAP, both on an annual and a cumulative basis cause differences between taxable results and the results are reflected in these financial statements.

2)   Tax rates

The net income of the Company is subject to the Israeli corporate tax rate. Israeli corporate tax rates is 23%.

b.   U.S. subsidiary:

The Company’s subsidiary is incorporated in the U.S. and is taxed under U.S. tax laws. The applicable corporate tax rate is 21%.  

As a general rule, inter-company transactions between the Israel-resident Company and its U.S-resident subsidiary are subject to the reporting provisions of the Income Tax Regulations, section 85-A, 2006 of the Israeli Tax Ordinance of the Israeli Tax Ordinance.

c.   Carryforward losses:

As of December 31, 2024, the Company had net operating loss (“NOLs”) carried forward of approximately $350 million. Under Israeli tax laws, carryforward tax losses have no expiration date.

As of December 31, 2024, the U.S. subsidiary had a net operating loss carryforward of approximately $45 million, with no expiriation date, but is limited to offset 80% of the net income in the year it is utilized.

Under U.S. tax laws, for NOLs arising after December 31, 2017, the 2017 Act limits a taxpayer’s ability to utilize NOL carryforwards to 80% of taxable income. In addition, NOLs arising after 2017 can be carried forward indefinitely, but carryback is generally prohibited. Furthermore, in accordance with Coronavirus Aid, Relief, and Economic Security Act (CARES Act) of 2020, losses from tax years beginning in 2018, 2019 or 2020 can be carried back 5 years.

Deferred tax assets on losses for tax purposes carried forward to subsequent years are recognized if utilization of the related tax benefit against a future taxable income is expected.  The Company has not created deferred taxes on its carryforward losses since their utilization is not expected in the foreseeable future.

d.   Deductible temporary differences:

The amount of cumulative deductible temporary differences, other than carryforward losses (as mentioned in c. above), for which deferred tax assets have not been recognized in the Statements of Financial Position as of December 31, 2024, and 2023, were $3 million and $6 million, respectively. These temporary differences have no expiration dates.

e.   Tax assessments:

The Company has not been assessed for tax purposes since its incorporation. The Company’s tax assessments for 2018 are therefore considered final.

v3.25.1
SHARE CAPITAL
12 Months Ended
Dec. 31, 2024
SHARE CAPITAL  
SHARE CAPITAL

NOTE 17 - SHARE CAPITAL:

a.  Composition:

Company share capital is composed of shares of NIS 0.01 par value, as follows:

Number of shares

December 31, 

    

2024

    

2023

Authorized ordinary shares (1)

39,994,000,000

19,994,000,000

Authorized preferred shares (reserved)

6,000,000

6,000,000

Issued and paid ordinary shares

 

12,899,831,000

7,869,853,000

Issued and paid – in ADSs term (2)

1,290,000

787,000

(1)On March 21, 2024, the extraordinary general meeting of shareholders approved the increase of the authorized share capital of the Company to NIS 400,000,000, consisting of (i) 39,994,000,000 Ordinary Shares, NIS 0.01 par value per share, and (ii) 6,000,000 preferred shares, NIS 0.01 par value per share

(2)On March 23, 2023, the Company changed the ADS ratio from 1 ADS representing 10 ordinary shares to 1 ADS representing 400 ordinary shares. On August 20, 2024, the Company changed the ADS to ordinary share ratio from 1 ADS representing 400 ordinary shares to 1 ADS representing 10,000 ordinary shares. All data denominated in ADS were adjusted for this ratio changes.
b.On January 26, 2024, the Company issued 400,000 ADSs at a purchase price of $20 per ADS and warrants to purchase 400,000 ADSs at an exercise price of $25 per ADS. These warrants may be exercised in cash or on a cashless basis, are immediately exercisable, and expire in five years. The Company also issued to the placement agent warrants to purchase 24,000 ADSs under the same terms. The gross proceeds from the offering were $8 million, before deducting approximately $0.9 million in fees and expenses.

The warrants were classified as a financial liability due to a net settlement provision. These derivatives were recognized and subsequently measured at fair value through profit or loss. Upon initial recognition the fair value of the warrants was adjusted to reflect the unrecognized day 1 loss. This unrecognized day 1 loss is amortized over the warrants’ contractual life. Issuance expenses amounted to $0.9 million allocated to the warrants were recorded directly in the Consolidated Statements of Comprehensive Income (Loss). See also note 4.

c.On April 3, 2024, the Company issued 85,779 ADSs at a purchase price of $14.57 per ADS and warrants to purchase 85,779 ADSs at an exercise price of $18.75 per ADS. These warrants may be exercised in cash or on a cashless basis, are immediately exercisable and expire in five years. The gross proceeds from the offering were $1.25 million, before deducting offering expenses approximately $0.1 million in expenses.

The warrants were classified as a financial liability due to a net settlement provision. These derivatives were recognized and subsequently measured at fair value through profit or loss. The consideration, net of issue expenses, was allocated to the various issued instruments. Out of the gross consideration, $0.9 million was allocated to the warrants. The remainder of approximately $0.35 million was allocated to equity. Issuance expenses allocated to the liability instruments were recorded directly in the Consolidated Statements of Comprehensive Income (Loss), while those allocated to equity were recorded against additional paid in capital. See also note 4.

d.During 2024, the Company issued 17,218 ADSs resulting from vested RSUs that had been issued to employees officers, directors and consultants of the Company.
e.On April 3, 2023, the Company completed a registered direct offering to an existing shareholder with gross proceeds to the Company of approximately $6 million, before deducting offering expenses of approximately $0.7 million. The offering consisted of 60,000 ADSs (or ADS equivalents which consist of pre-funded warrants with an exercise price of $0.025 per pre-funded warrant) as well as granted (i) Series A unregistered private warrants to purchase up to 60,000 ADSs, which had an exercise price of $118.75 per ADS (subsequently reduced to $33.75 per ADS as described below), were exercisable immediately after the issuance date and had a term of 5 years and (ii) Series B unregistered private warrants to purchase up to 60,000 ADSs, which had an exercise price of $100.00 per ADS (subsequently reduced to $45 per ADS as described below), were exercisable immediately after the issuance date and had a term of 9 months.  In addition, as part of the offering the Company has agreed to amend certain existing warrants to purchase up to 13,204 ADSs with an exercise price of $1,480 per ADS and a termination date of November 11, 2027. The amended warrants have a reduced exercise price of $118.75 per ADS and a termination date of 5 years following the closing of the offering.

The warrants that were issued to the investors may be exercised either for cash or on a cashless basis and were classified as financial liability due to a net settlement provision. Loss from modification of warrants terms as part of the new registered offering with an existing shareholder, in an amount of $0.9 million, was included as a financial expense. See also note 17(c) regarding amendment to the above warrants.

The Company has issued to the placement agent warrants to purchase up to 3,600 ADSs with an exercise price of $125 per ADS, exercisable for 5 years.  These warrants were classified to the Equity.

f.On July 25, 2023, the Company completed a registered direct offering to existing shareholders of 52,077 ADSs (or ADS equivalent which consist of pre-funded warrants with an exercise price of $0.025 per pre-funded warrant), for gross proceeds of approximately $1.8 million, before deducting offering expenses of approximately $0.4 million. In connection with this offering, the Company also agreed with the investors in this offering on the following:
(i)To reduce the exercise price to $45.00 per ADS to the following existing warrants: (1) warrants originally issued on May 11, 2022 and subsequently amended on April 3, 2023, to purchase up to an aggregate of 13,204 ADSs at an exercise price of $118.75 per ADS, (2) warrants issued on December 6, 2022 to purchase up to an aggregate of 38,873 ADSs at an exercise price of $115.76 per ADS, and (3) Series B Warrants issued on April 3, 2023 to purchase up to an aggregate of 60,000 ADSs at an exercise price of $100.00 per ADS.
(ii)Series A Warrants issued on April 3, 2023, to purchase 60,000 ADSs, will be exercised at a reduced exercise price of $33.75 per ADS, for gross proceeds of $2 million. New unregistered private warrants to purchase up to 60,000 ADSs will be granted to the same investor. The new warrants have an exercise price of $45.00 per ADS, are exercisable 6 months after the issuance date and have a term of 5 years.

The warrants that were issued to the investors may be exercised either for cash or on a cashless basis and were classified as financial liability due to a net settlement provision.

As part of the offering, the Company has issued to the placement agent warrants (i) to purchase up to 3,125 ADSs with an exercise price of $42.19 per ADS, exercisable for 5 years (ii) to purchase up to 3,600 ADSs with an exercise price of $42.19 per ADS, exercisable for 4.7 years. These warrants were classified to the Equity.

g.On September 28, 2023, the Company entered into a warrant reprice and reload letter of certain existing warrants to purchase (i) up to 13,204 ADSs with an exercise price of $45.00 per ADS and a termination date of April 3, 2028, (ii) up to 38,873 ADSs with an exercise price of $45.00 per ADS and a termination date of December 6, 2027, (iii) up to 60,000 ADSs with an exercise price of $45.00 per ADS and a termination date of January 3, 2024, and (iv) up to 60,000 ADSs with an exercise price of $$45.00 per ADS and a termination date of April 3, 2028, pursuant to which such investors agreed to exercise their existing warrants in full at a reduced exercise price of $11.75 per ADS for aggregate gross proceeds of approximately $2.0 million, before deducting offering expenses of approximately $0.2 million. In exchange, the exercising holders received new unregistered warrants to purchase up to an aggregate 344,154 ADSs at an exercise price of $11.75 per ADS and with exercise terms ranging from eighteen months to five years.

As part of the offering, the Company has issued to the placement agent warrants to purchase up to 10,325 ADSs with an exercise price of $14.69 per ADS, exercisable for 5 years. These warrants were classified to the Equity.

h.Between November 27, 2023, and November 29, 2023, the warrants issued in September 2023 as described above were exercised for a total of approximately $4 million gross proceeds to the Company.
i.The fair value of the warrants that were issued to the investors was computed using the Black and Scholes option pricing model. The fair value of the outstanding warrants that were issued to the investors as of December 31, 2024, was based on the price of an ADS on December 31, 2024, and based on the following parameters: risk-free interest rates of 4.27%-4.34% and an average standard deviation of 131.6%-148.37%.
j.During 2023, the Company issued 1,893 ADSs resulting from vested RSUs that had been issued to employees and consultants of the Company.
v3.25.1
SHARE-BASED PAYMENTS
12 Months Ended
Dec. 31, 2024
SHARE-BASED PAYMENTS  
SHARE-BASED PAYMENTS

NOTE 18 - SHARE-BASED PAYMENTS:

On May 30, 2010, a general meeting of shareholders approved the option plan of the Company (the “Option Plan”), after being approved by the BoD. In 2017 the Option Plan was amended and restated as the 2010 Award Plan (the “Award Plan”). As of December 31, 2024, the Award Plan allows the Company to allocate up to 2,717,305,440 options to purchase ordinary shares and RSUs (equivalent to 271,730 ADSs) to employees, consultants, and directors and are reserved by the BoD for issuance under the Award Plan. The terms and conditions of the grants were determined by the BoD and are according to the Award Plan.

b.On June 24, 2024, the BoD granted 41,760 RSUs to employees and consultants. These RSUs will vest in 8 equal quarterly installments over two years and had a fair value of $0.4 million on the grant date, based on the ADS price on that date. In addition, the general meeting of the Company’s shareholders held on September 18, 2024, subsequent to approval of the Company’s BoD in June 2024, approved grant of 15,320 RSUs for directors and the Company's Chief Executive Officer and Chief Commercial Officer in the same terms. The fair value of these RSUs on the date of approval was $0.1 million.

     During 2024, approximately 2,584 options and RSUs were forfeited, resulting in $0.3

million in reversed expenses.

c.On July 1, 2023, The Board of Directors of the Company granted 7,500 RSUs to the employees and consultants of the Company. The RSUs will vest in 12 equal quarterly installments over a three-year period. The fair value for the RSUs grant on the date of the grant was $0.2 million. The fair value of the RSUs was determined based on the price of an ADS on the date the RSUs were granted.

During 2023, approximately 2,720 options and RSUs were forfeited, resulting in $1.6 million in reversed expenses.

c.    Changes in the number of options in ADSs and weighted averages of exercise prices are as follows:

Year Ended December 31, 

2024

2023

Weighted 

Weighted 

average of

average of

Number of 

exercise

Number of 

exercise

    

options

    

price ($)

    

options

    

price ($)

Outstanding at beginning of year

3,894

6,324.50

5,259

6,390.00

Exercised

 

 

Expired and forfeited

 

(1,275)

 

6,277.89

 

(1,365)

 

6,560.75

Outstanding at end of year

 

2,619

 

6,329.96

 

3,894

 

6,324.50

Exercisable at end of year

 

2,525

 

6,310.15

 

3,455

 

6,228.50

d. Changes in the number of RSUs in ADSs during the period are as follows:

Year Ended December 31, 

2024

2023

Number of 

Number of 

    

RSUs

    

RSUs

    

Outstanding at beginning of year

7,121

3,646

Exercised

 

(23,938)

(2,658)

Expired and forfeited

 

(2,497)

 

(1,367)

 

Granted

 

57,080

 

7,500

 

Outstanding at end of year

 

37,766

 

7,121

 

e.The following is information about the exercise price and remaining useful life of outstanding options at year-end:

Year Ended December 31, 

2024

2023

Number of

Number of

options

Weighted

options

Weighted

outstanding

average of

outstanding

average of

at end of

Exercise price

remaining

at end of

Exercise price

remaining

year

    

range

    

useful life

    

year

    

range

    

useful life

2,619

$1,670-$10,370

5.04

3,894

$1,670-$10,900

5.2

f.    Expenses recognized in profit or loss for the options and RSUs are as follows:

Year Ended December 31, 

2024

    

2023

    

2022

U.S. dollars in thousands

665

1,647

5,675

The remaining compensation expenses as of December 31, 2024, are $0.2 million and will be expensed in full by December 2026.

v3.25.1
NET REVENUES
12 Months Ended
Dec. 31, 2024
NET REVENUES  
NET REVENUES

NOTE 19 - NET REVENUES:

Year Ended December 31, 

    

2024

2023

2022

U.S dollars in thousands

Licensing revenues (1)

547

2,000

Sales of products (2)

7,496

6,530

59,800

 

 

8,043

 

6,530

61,800

(1)Revenues related to the license agreement with Gaelan for Talicia® in the UAE, see note 15(7) above.
(2)In 2024 and 2023, the Company recognized contra-revenues of ($0.9) million and ($2.6) million, respectively, for Movantik®, primarily due to returns following its divestiture on February 1, 2023 (see note 15(6) above). In 2022, net revenues for Movantik® were $52.1 million. Correspondingly, in 2024, 2023 and 2022, net revenues from sales of other products (mainly Talicia®) were $8.4 million, $9.1 million, and $7.7 million, respectively.
v3.25.1
RESEARCH AND DEVELOPMENT EXPENSES
12 Months Ended
Dec. 31, 2024
RESEARCH AND DEVELOPMENT EXPENSES.  
RESEARCH AND DEVELOPMENT EXPENSES

NOTE 20 - RESEARCH AND DEVELOPMENT EXPENSES:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

222

390

661

Professional services

 

708

 

605

1,210

Share-based payments

 

156

 

138

 

1,151

Clinical and pre-clinical trials

 

114

 

1,891

 

3,872

Intellectual property development

 

238

 

222

 

180

Other

 

150

 

282

 

205

 

1,588

 

3,528

 

7,279

v3.25.1
SELLING AND MARKETING EXPENSES
12 Months Ended
Dec. 31, 2024
SELLING AND MARKETING EXPENSES  
SELLING AND MARKETING EXPENSES

NOTE 21 - SELLING AND MARKETING EXPENSES:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

3,076

9,656

19,235

Share-based payments

 

(41)

 

(51)

 

553

Professional services

 

1,913

 

3,056

 

6,596

Samples

54

836

Travel, Fleet, meals and related expenses

302

736

5,136

Office-related expenses

 

329

 

566

 

1,510

Other

 

371

 

739

 

1,576

 

5,950

 

14,756

 

35,442

v3.25.1
GENERAL AND ADMINISTRATIVE EXPENSES
12 Months Ended
Dec. 31, 2024
GENERAL AND ADMINISTRATIVE EXPENSES  
GENERAL AND ADMINISTRATIVE EXPENSES

NOTE 22 - GENERAL AND ADMINISTRATIVE EXPENSES:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

4,515

7,035

10,521

Share-based payments

 

550

 

1,560

 

3,971

Professional services and supply chain

 

3,118

 

5,391

 

10,787

Medical affairs

131

818

1,214

Office-related expenses

 

749

 

958

 

1,434

Other

 

504

 

457

 

659

 

9,567

 

16,219

 

28,586

v3.25.1
FINANCIAL INCOME (EXPENSES), net
12 Months Ended
Dec. 31, 2024
FINANCIAL INCOME (EXPENSES), net  
FINANCIAL INCOME (EXPENSES), net

NOTE 23 - FINANCIAL INCOME (EXPENSES), net:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S dollars in thousands

Financial income:

Fair value gains on derivative financial instruments

 

8,228

 

 

13,422

Gains on extinguishment of debt obligations by transfer of the rights in Movantik

20,585

Other Income

 

40

 

210

 

Interest from bank deposits

 

133

 

94

 

140

 

8,401

 

20,889

 

13,562

Financial expenses:

 

  

 

  

 

  

Interest for lease liabilities

55

367

430

Issuance cost in respect of warrants

1,497

2,034

958

Loss from changes in exchange rates

 

31

 

115

 

40

Fair value loss on derivative financial instruments

5,569

Loss from modification of warrants terms as part of a new issuance, see notes 17(b) and 17(d)

1,459

Interest expenses related to borrowing and payable in respect of intangible assets purchase

40,903

Other

 

473

 

61

 

56

 

2,056

 

9,605

 

42,387

Financial income (expenses), net

 

6,345

 

11,284

 

(28,825)

(

v3.25.1
SEGMENT INFORMATION
12 Months Ended
Dec. 31, 2024
SEGMENT INFORMATION  
SEGMENT INFORMATION

NOTE 24 - SEGMENT INFORMATION:

The Chief Executive Officer is the Company’s Chief Operating Decision Maker (“CODM”). The CODM allocates resources and assesses the Company’s performance based on the following segmentation: Commercial Operations and Research & Development.

Adjusted EBITDA represents net loss before depreciation, amortization, and financial income (expenses), adjusted to exclude share-based compensation, gains from early termination of leases, and other income, which includes income from service provided to HCRM and gain from the sale of Movantik®, and other expense from the Global Termination Agreement.

The following table presents segment profitability and a reconciliation to the consolidated net income (loss) and comprehensive income (loss) for the periods indicated:

Year Ended December 31, 

2024

2023

2022

    

U.S. dollars in thousands

Commercial Operations Segment Adjusted EBITDA

(5,864)

(20,173)

(16,595)

Research And Development Adjusted EBITDA

(5,129)

(8,165)

(12,420)

Financial income (expenses), net

6,346

11,284

(28,825)

Share-based compensation to employees and service providers

(665)

(1,647)

(5,675)

Depreciation

(588)

(1,445)

(2,136)

Amortization of intangible assets

(31)

(545)

(6,018)

Gain from early termination of lease

22

543

Other income (expenses)

(2,359)

44,064

Consolidated Comprehensive income (loss)

(8,268)

23,916

(71,669)

Supplementary information on material income or expense items included in the segment results:

Licensing revenues included in the Research And Development Adjusted EBITDA

547

2,000

Loss from Global Termination Agreement included in the Commercial Operations Segment, not included in the Adjusted EBITDA

(2,359)

Gain from the sale of Movantik®, included in the Commercial Operations Segment, not included in the Adjusted EBITDA

44,064

b.   Major customers

The following table represents the percentages of total net revenues from the major customers:

Year Ended December 31, 

2024

2023

2022

Customer A

36%

30%

32%

Customer B

22%

28%

30%

Customer C

30%

37%

33%

The Company’s revenues were entirely in the U.S. except for approximately $1 million from licensing revenues (including royalties) and sales of product to Gaelan in the UAE in 2024, no revenues outside the U.S. in 2023, and $2 million from licensing revenues to Gaelan in the UAE in 2022. The payment terms for all customers are 31 to 68 days.

c.   Assets by geographic location

The Company’s non-current assets located in Israel as of December 31, 2024, amount to $6.1 million (mainly intangible assets - $5.5 million and right-of-use assets - $0.3 million).

The Company’s non-current assets located in Israel as of December 31, 2023, amount to $6.4 million (mainly intangible assets - $5.6 million and right-of-use assets - $0.6 million). The remainder of the consolidated non-current assets as of December 31, 2023, amount to $0.5 million and are located in the U.S (consisting mainly right-of-use assets - $0.4 million).

v3.25.1
EARNINGS (LOSS) PER ORDINARY SHARE
12 Months Ended
Dec. 31, 2024
EARNINGS (LOSS) PER ORDINARY SHARE  
EARNINGS (LOSS) PER ORDINARY SHARE

NOTE 25 – EARNINGS (LOSS) PER ORDINARY SHARE:

a.Basic

The following is data taken into account in the computation of basic loss per share:

Year Ended December 31, 

    

2024

    

2023

    

2022

Earnings (Loss) (U.S. dollars in thousands)

(8,268)

23,916

(71,669)

Weighted average number of ordinary shares outstanding during the period (in thousands)

 

12,322,721

 

2,591,222

 

616,299

Basic earnings (loss) per share (U.S. dollars)

 

(0.00)

 

0.01

 

(0.12)

 

b.Diluted

The Company had three categories of potentially dilutive ordinary shares: warrants issued to investors and options issued to employees and service providers. The effect of these options, RSUs and warrants for all reporting years is anti-dilutive.

The calculation of diluted earnings (loss) per share as of December 31, 2024, does not include 5,606,626,800 of ordinary shares underlying warrants, 26,190,400 of ordinary shares underlying options and 377,659,600 of ordinary shares underlying RSUs, because the effect would be anti-dilutive.

v3.25.1
RELATED PARTIES
12 Months Ended
Dec. 31, 2024
RELATED PARTIES  
RELATED PARTIES

NOTE 26 - RELATED PARTIES:

a.    Key management includes members of the Board of Directors, including the Company’s Chief Commercial Officer and Chief Executive Officer:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Key management compensation:

Salaries and other short-term employee benefits

 

1,030

 

1,189

 

1,486

Post-employment benefits

 

49

 

56

 

64

Share-based payments

 

205

 

407

 

1,041

Other long-term benefits

 

31

 

35

 

44

b.    Balances with related parties:

December 31, 

    

2024

    

2023

U.S. dollars in thousand

Current liabilities -

  

  

Credit balance in “accrued expenses and other current liabilities”

 

176

 

206

v3.25.1
EVENT SUBSEQUENT TO DECEMBER 31, 2024
12 Months Ended
Dec. 31, 2024
EVENT SUBSEQUENT TO DECEMBER 31, 2024  
EVENT SUBSEQUENT TO DECEMBER 31, 2024

NOTE 27 - EVENTS SUBSEQUENT TO DECEMBER 31, 2024:

1)Through April 10, 2025, the Company sold 453,345 ADSs under its “at-the-market” (“ATM”) program at an average price of $4.96 per ADS, generating net proceeds of approximately $2.2 million, net of an immaterial amount of issuance expenses. The Company may sell up to $3.5 million in aggregate gross proceeds under the program.
2)On February 24, 2025, the Company entered into an exclusive license agreement with Hyloris Pharmaceuticals SA for the development and commercialization of RHB-102 (Bekinda®) in all territories outside the United States, Canada and Mexico. Under the agreement, the Company received an upfront payment of $0.1 million and is entitled to up to $60 million in potential milestone payments, and tiered royalties of up to the mid-20% on net sales, subject to certain cost recoupments, with minimum annual payments to the Company.

v3.25.1
Insider Trading Policies and Procedures
12 Months Ended
Dec. 31, 2024
Insider Trading Policies and Procedures [Line Items]  
Insider Trading Policies and Procedures Adopted true
v3.25.1
Cybersecurity Risk Management and Strategy Disclosure
12 Months Ended
Dec. 31, 2024
Cybersecurity Risk Management, Strategy, and Governance [Line Items]  
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block] Our current cybersecurity risk assessment program consists of an annual review of the technical safeguards that have been implemented to ensure they align with industry best practices and evolving risks. As part of this program, we leverage the advice of third-party consultants and auditors to help us assess and identify risks from cybersecurity threats, including the threat of a cybersecurity incident, and manage our risk assessment program. Among other things, these providers perform regular audits, ongoing monitoring of network traffic and system logs for suspicious activity, periodic employee training on cybersecurity best practices, and implementation of encryption protocols for sensitive data. Our cybersecurity risk assessment program outlines governance, policies and procedures and technology to oversee and identify risks from cybersecurity threats, and we are informed by previous cybersecurity incidents we have observed both within the Company and in our industry. All cyber incidents are reported to a designated RedHill email after a review by our Security Operation Center (“SOC”). Such emails contain a full description as to what has happened and how the incident was mitigated
Cybersecurity Risk Management Processes Integrated [Flag] true
Cybersecurity Risk Management Processes Integrated [Text Block] Our current cybersecurity risk assessment program consists of an annual review of the technical safeguards that have been implemented to ensure they align with industry best practices and evolving risks
Cybersecurity Risk Management Third Party Engaged [Flag] true
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag] true
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag] false
Cybersecurity Risk Board of Directors Oversight [Text Block] Our Board of Directors is responsible for the oversight of risks from cybersecurity threats in conjunction with our Audit Committee
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block] Board of Directors and our Audit Committee
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block] Our Board of Directors and our Audit Committee receive from time to time reports and updates from our management with respect to the management of risks from cybersecurity threats
Cybersecurity Risk Role of Management [Text Block] Our management, with assistance of our virtual Chief Information Security Officer (“vCISO”), is responsible for the day-to-day assessment and management of risks from cybersecurity threats, including the prevention, mitigation, detection, and remediation of cybersecurity incidents.
Cybersecurity Risk Management Positions or Committees Responsible [Flag] true
Cybersecurity Risk Management Positions or Committees Responsible [Text Block] management, with assistance of our virtual Chief Information Security Officer (“vCISO”),
Cybersecurity Risk Management Expertise of Management Responsible [Text Block] The individuals currently serving in these roles are Razi Ingber, our CFO, and Eli Migdal, Founder and Head of Cyber Security for Migdal Computing Solutions LTD. Migdal Computing Solutions LTD also provides us with certain cybersecurity services, including vCISO, Security Operation Center, risk assessment,  risk quantification, server-level penetration testing, planning, deployment and management of most modern cybersecurity solutions. Pursuant to our cybersecurity risk assessment program, our vCISO is notified about every cybersecurity event, and as the vCISO he approves the actions that were taken and transforms SOC cases to be marked as completed
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block] Pursuant to our cybersecurity risk assessment program, our vCISO is notified about every cybersecurity event, and as the vCISO he approves the actions that were taken and transforms SOC cases to be marked as completed
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag] true
v3.25.1
SUMMARY OF MATERIAL ACCOUNTING POLICIES (Policies)
12 Months Ended
Dec. 31, 2024
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES  
Basis for presentation of the financial statements

a.    Basis for presentation of the financial statements

The consolidated financial statements of the Company have been prepared in accordance with IFRS Accounting Standards as issued by the International Accounting Standards Board. (“IASB”).

The material accounting policies described below have been applied consistently in relation to all the periods presented, except for the adoption of IAS 1 amendments effective January 1, 2024, as described in note 2(m)(1).

The preparation of financial statements in conformity with IFRS requires the use of certain critical accounting estimates. It also requires management to exercise its judgment in applying the Company’s accounting policies. The areas involving a higher degree of judgment or complexity, or areas where assumptions and estimates are material to the financial statements, are disclosed in note 3. Actual results could differ significantly from those estimates and assumptions.

Translation of foreign currency transactions and balances

b.    Translation of foreign currency transactions and balances

1)    Functional and presentation currency

Items included in the consolidated financial statements are measured using the currency of the primary economic environment in which the Company and its subsidiary operate (the “Functional Currency”). The consolidated financial statements are presented in U.S. dollars (“$”), which is the Company’s functional and presentation currency.

2)   Transactions and balances

Foreign currency transactions in currencies different from the Functional Currency (hereafter foreign currency, mostly New Israeli Shekel (“NIS”) and Euro are translated into the Functional Currency using the exchange rates at the dates of the transactions. Foreign exchange differences resulting from the settlement of such transactions and from the translation of period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recorded in the Consolidated Statements of Comprehensive Income (Loss) under financial income or financial expenses.

Trade receivables

c.    Trade receivables  

Trade receivables are recognized initially at the amount of consideration that is unconditional. They are subsequently measured at amortized cost, less allowance for expected credit losses. The Company measures the loss allowance for expected credit losses on trade receivables based on lifetime expected credit losses.

Inventory

d.     Inventory

The Company’s inventory is stated at the lower of cost or net realizable value. Cost of inventory is determined using the first-in, first-out method.

Net realizable value is the estimated selling price in the ordinary course of business, less the estimated costs of completion and the estimated costs necessary to make the sale.

The Company continually evaluates inventory for potential loss due to excess quantity or obsolete or slow-moving inventory by comparing sales history and sales projections to the inventory on hand. When evidence indicates that the carrying value of a product may not be recoverable, a charge is recorded to reduce the inventory to its current net realizable value.

Fixed assets

                           

Fixed assets items are stated at cost less accumulated depreciation.

Depreciation is computed by the straight-line method, to reduce the cost of fixed assets to their residual value over their estimated useful lives as follows:

    

%

 

Computer equipment

33

Office furniture and equipment

8-15

Leasehold improvements are depreciated by the straight-line method over the shorter of the term of the lease or the estimated useful life of the improvements.

Intangible assets

f.    Intangible assets

1)    Licenses

The Company’s intangible assets represent in-licenses of development-phase compounds acquired by the Company, where the Company continues or has the option to continue to do the development work (“R&D assets”), as well as commercialization rights for approved products ("Commercialization assets") which were fully derecognized in 2023 as part of the sale of the rights to Movantik® asset (See also note 15(6)).

R&D assets that are available for use are stated at cost and amortized on a straight-line basis over their useful life from the time they are available for use. R&D assets that are not available for use are not amortized and are tested for impairment at least annually.

Amounts due for future payments based on contractual agreements are accrued upon reaching the relevant milestones.

All intangible assets are tested for impairment if any events have occurred or changes in circumstances have taken place which might indicate that their carrying amounts may not be recoverable. See also note 3 for key assumptions used in the determination of the recoverable amounts.

Research and development

2)    Research and development

Research expenses are recognized as an expense as incurred.

Research and development costs for the performance of pre-clinical trials, clinical trials, and    manufacturing by subcontractors are recognized as expenses when incurred.

Financial liabilities

g.     Financial liabilities

Non-derivative financial liabilities are initially recognized at their fair value minus transaction costs and are subsequently measured at amortized cost. In case there is a difference between the fair value at initial recognition and the transaction price (“day 1 loss”), the financial liabilities are adjusted to reflect the day 1 loss and changes are recorded to profit or loss while unrecognized day 1 loss is amortized over the contractual life of the instrument. Any amounts not recognized in profit or loss before the date of exercise or maturity will be recognized in profit or loss on that date.

Warrants exercisable to the Company’s ordinary shares are classified as an equity instrument only if the warrants are settled by the Company exchanging a fixed amount of cash for a fixed number of its own equity instruments (the ‘fixed for fixed’ criteria). Otherwise, the warrants are classified as a derivative financial liability measured at fair value through profit or loss.

Transaction costs relating to the issuance of derivative financial liabilities measured at fair value through profit or loss are expensed to profit or loss.

Financial liabilities are included in current liabilities, except for those with maturities greater than 12 months after the Statements of Financial Position date (for which they are classified as noncurrent liabilities).

Financial liabilities are derecognized when, and only when, they are extinguished. The difference between the carrying amount of the financial liability extinguished and the consideration paid, including any non-cash assets transferred, is recognized in profit or loss. As for the accounting for the extinguishment of the financial liability to HCR, as well as the Global Termination Agreement which terminated all remaining credit ties related to this transaction, see note 15(6).  

Share-based payments

The Company operates several equity-settled, share-based compensation plans to employees and service providers. As part of the plans, the Company grants employees and service providers, from time to time and at its discretion, options to purchase Company shares. For employees, the total amount recognized as an expense over the vesting period of the options is determined by reference to the fair value of the options at the grant date. For service providers, the Company measures the awards based on the fair value of the asset or service received. The amounts are recorded against the accumulated deficit within equity.

Vesting conditions (other than market conditions) are included in the assumptions about the number of options that are expected to vest.

At the end of each reporting period, the Company revises its estimates of the number of options that are expected to vest based on non-market vesting conditions. The Company recognizes the impact of the revision to original estimates, if any, in profit or loss, with a corresponding adjustment to accumulated deficit.

When exercising options, the Company issues new shares. The proceeds, less directly attributable transaction costs, are recognized as share capital (par value) and additional paid-in capital. 

Revenue from contracts with customers

i.    Revenue from contracts with customers

The Company generated revenue in the years presented in these financial statements mainly from product sales, including in-licensed products.

1)    Revenue from the sale of products

The Company sells products mainly to wholesale distributors. Revenue is recognized at a point in time when control over the product is transferred to the customer (upon delivery), at the net selling price, which reflects reserves for variable consideration, including discounts and allowances.

The Company estimates variable consideration and includes it in the transaction price only to the extent it is highly probable that a significant reversal of cumulative revenue recognized will not occur when the uncertainty associated with the variable consideration is subsequently resolved.

The specific considerations the Company uses in estimating these amounts related to variable consideration are as follows:

Trade discounts and distribution fees - The Company offers discounts to its customers, as an incentive for prompt payment. The Company records these discounts as a reduction of revenue in the period the related revenue from the sale of products is recognized. In addition, distribution fees are paid to certain distributors based on contractually determined rates from the gross consideration. As the fee paid to the customer is not for a distinct good or service, it is recognized as a reduction of revenue in the period the related revenue from the sale of products is recognized.

Rebates and patient discount programs - The Company offers various rebate and patient discount programs, which result in discounted prescriptions to qualified patients. The Company estimates the allowance for these rebates and coupons based on historical and estimated utilization of the rebate and discount programs, at the time the revenues are recognized. These estimates are recognized as a reduction of revenue. See also notes 3 and 13.

Product returns - The Company offers customers a right of return of expired products. The Company estimates the amount of product sales that may be returned by its customers and records this estimate as a reduction of revenue at the time of sale, based on historical rates of return, or, if such historical data is not available, the Company estimates product returns based on its own sales information, its visibility into the inventory remaining in the distribution channel and product dating.

2) Practical expedients and exemptions

The Company expenses sales commissions when incurred since the amortization period of the asset that the Company otherwise would have recognized would have been for less than one year. These costs are recorded as selling and marketing expenses. 

3)    Revenues from licensing

Licenses of intellectual property (“IP”) rights are distinct from other promises in a contract with a customer (such as manufacturing and supply services) if the customer can benefit from the IP either on its own or together with other resources that are readily available to the customer and if the Company’s promise to license the IP is separately identifiable from other promises in the contract.  

If the promise to grant the license is distinct, the Company determines whether the nature of the promise in granting the license is to provide the customer with either a right to access the Company’s IP as it exists throughout the license period or a right to use the Company’s IP as it exists at the point in time at which the license is granted. Accordingly, revenue from a license providing a right of use to the Company’s IP is recognized at the point in time when control of the distinct license is transferred to the customer.

Sales -based royalties that are allocated to license of IP are recognized only when (or as) the later of the following occurs: (a) the subsequent sale occurs; and (b) the performance obligation to which some or all the sales-based royalty has been allocated has been satisfied (or partially satisfied).

The Company applies a practical expedient in the standard and does not adjust the transaction price for the effects of significant financing components if, at contract inception, the Company expects the period between customer payment and the transfer of goods or services to be one year or less.

Revenue from achieving additional milestones is recognized only when it is highly probable that a significant reversal of cumulative revenues will not occur, usually upon achievement of the specific milestone, in accordance with the relevant agreement.

Earnings (Loss) per share

j.    Earnings (Loss) per share

The computation of basic earnings (loss) per share is based on the Company’s earnings (loss) divided by the weighted average number of ordinary shares and pre-funded warrants outstanding during the period.

In calculating the diluted earnings (loss) per share, using the treasury stock method, the Company adds the weighted average of the number of shares to be issued to the average number of shares outstanding including pre-funded warrants used to calculate the basic earnings (loss) per share, assuming all shares that have a potentially dilutive effect have been exercised into shares. 

Deferred taxes

k.    Deferred taxes

Since the Company is unable to assess whether it will have taxable income in the foreseeable future, no deferred tax assets were recorded in these financial statements. 

Leases

l.    Leases

The leases are recognized as a right-of-use asset and a corresponding liability at the date at which the leased asset is available for use by the Company. Each lease payment is allocated between the liability and finance cost. The finance cost is charged to profit or loss over the lease period so as to produce a constant periodic rate of interest on the remaining balance of the liability for each period.

The right-of-use asset is depreciated over the shorter of the asset’s useful life and the lease term on a straight-line basis.

Assets and liabilities arising from a lease are initially measured on a present value basis. Lease liabilities include the net present value of fixed lease payments and variable lease payments that are based on an index or a rate.

The lease payments are discounted using the lessee’s incremental borrowing rate, as the interest rate implicit in the lease is not readily determined.

Right-of-use assets are measured at cost being the amount of the initial measurement of the lease liability.

Payments associated with short-term leases and leases of low-value assets are not recognized as right-of-use assets or lease liabilities but are recognized on a straight-line basis as an expense in profit or loss. Short-term leases are leases with a lease term of 12 months or less. Low-value assets include IT-equipment and small items of office furniture.

Contracts may contain both lease and non-lease components. For leases of properties, the Company allocates the consideration in the contract to the lease and non-lease components based on their relative stand-alone prices. However, for leases of vehicles, the Company has elected not to separate lease and non-lease components and instead accounts for these as a single lease component.

New international financial reporting standards, amendments to standards and new interpretations

m.    New international financial reporting standards, amendments to standards and new interpretations:

1)Classification of Liabilities as Current or Non-Current (Amendment to IAS 1)

The narrow-scope amendments to IAS 1, “Presentation of Financial Statements,” clarify that liabilities are classified as either current or noncurrent, depending on the rights that exist at the end of the reporting period. Classification is unaffected by the entity’s expectations or events after the reporting date. The amendments also clarify what IAS 1 means when it refers to the settlement’ of a liability. The amendments may affect the classification of liabilities, particularly for entities that previously considered management’s intentions to determine classification and for some liabilities that can be converted into equity. The Company adopted these amendments effective January 1, 2024. The impact on the Company’s financial statements of these amendments was the reclassification of the Company’s derivative financial instruments from non-current to current as of its effective date, as the Company does not have the right to defer settlement of liability for at least twelve months after the reporting period. The Company has retrospectively applied the amendments in these interim financial statements and, accordingly, has retrospectively adjusted the comparative balance sheet for December 31, 2023, to reclassify its warrant liabilities ($741 as of December 31, 2023) from non-current to current. Adoption of the amendments had no other impact on the Company’s financial statements.

2)In its July 2024 Board meeting, the IASB approved an IFRIC agenda decision on ‘Disclosure of Revenues and Expenses for Reportable Segments (IFRS 8 Operating Segments)’. IFRS 8 Operating Segments requires an entity to disclose specific information about assets, liabilities and profit or loss by segment. Specifically, IFRS 8 paragraph 23 requires an entity to disclose certain specified items of profit or loss if these are included in the measure of segment profit or loss reviewed by the chief operating decision maker or are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. Management of the Company has implemented the agenda decision in these December 2024 annual financial statements (see note 24).
3)IFRS 18, Presentation and Disclosure in the Financial Statements

This standard replaces the international accounting standard IAS 1, “Presentation of Financial Statements.” As part of the new disclosure requirements, companies will be required to present new defined subtotals in the statements of income, as follows: (1) operating profit and (2) profit before financing and tax. In addition, income statement items will be classified into three defined categories: operating, investment and financing. The standard also includes a requirement to provide a separate disclosure in the financial statements regarding the use of management-defined performance measures (“non-GAAP measures”), and specific instructions were added for the grouping and splitting of items in the financial statements and in the notes to the financial statements. IFRS 18 is effective for annual reporting periods beginning on or after January 1, 2027, with an option for early adoption.

v3.25.1
SUMMARY OF MATERIAL ACCOUNTING POLICIES (Tables)
12 Months Ended
Dec. 31, 2024
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES  
Schedule of estimated useful lives of fixed assets

    

%

 

Computer equipment

33

Office furniture and equipment

8-15

v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT (Tables)
12 Months Ended
Dec. 31, 2024
FINANCIAL INSTRUMENTS  
Schedule of company's financial liabilities and estimated maturities

Contractual maturities of financial liabilities
As of  December 31, 2024

Less than 1 year

2-5 years

More than 5 years

Total contractual cash flows

Carrying amount

U.S. Dollars in Thousands

Account payable

1,168

1,168

1,168

Lease liabilities

365

3

368

356

Accrued expenses and other current liabilities

9,993

9,993

9,993

Royalty obligation

137

1,246

1,383

500

Total

11,526

140

1,246

12,912

12,018

Contractual maturities of financial liabilities
As of  December 31, 2023

Less than 1 year

2-5 years

More than 5 years

Total contractual cash flows

Carrying amount

U.S. Dollars in Thousands

Accounts payable

3,278

3,278

3,278

Lease liabilities

766

475

1,241

1,173

Accrued expenses and other current liabilities

4,592

4,592

4,592

Royalty obligation

282

1,553

1,835

540

Total

8,636

757

1,553

10,946

9,583

Schedule of change in derivative financial instrument

Derivative financial instruments

Year Ended December 31, 

    

    

2024

    

2023

 

U.S. dollars in thousands

Balance at beginning of the period

741

2,623

Initial recognition of financial liability

9,860

10,932

Initial recognition of unrecognized day 1 loss

(952)

Exercise of financial liability  

(18,383)

Fair value adjustments and recognition of day 1 loss recognized in profit or loss

(8,228)

5,569

Balance at end of the period

1,421

741

Schedule of reconciliation of liabilities arising from financing activities

U.S. dollars in thousands

Non-cash changes

January 1, 2024

Principal and interest payments (includes credits)

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2024

Payables in respect to the global termination agreement (See note 15(6)(b))

11,443

(4,750)

6,693

Lease liabilities

1,173

(691)

(188)

55

7

356

Non-cash changes

January 1, 2023

Principal and interest payments

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2023

Borrowing

115,216

(115,216)

Payable in respect of intangible assets purchase

11,157

(6,555)

(4,602)

Lease liabilities

7,475

(1,529)

270

(5,413)

367

3

1,173

Non-cash changes

January 1, 2022

Principal and interest payments

Addition during the year

Decreases during the year

Interest expense

Foreign exchange movement

12/31/2022

Borrowing

83,620

(7,507)

39,103

115,216

Payable in respect of intangible assets purchase

20,480

(11,123)

1,800

11,157

Lease liabilities

4,192

(2,010)

5,003

430

(140)

7,475

v3.25.1
CASH AND CASH EQUIVALENTS (Tables)
12 Months Ended
Dec. 31, 2024
CASH AND CASH EQUIVALENTS.  
Schedule of cash and cash equivalents

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Cash in bank

1,882

5,569

Short-term bank deposits

 

2,735

 

-

 

4,617

 

5,569

v3.25.1
PREPAID EXPENSES AND OTHER RECEIVABLES (Tables)
12 Months Ended
Dec. 31, 2024
PREPAID EXPENSES AND OTHER RECEIVABLES  
Schedule of prepaid expenses and other receivables

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Advance to suppliers

77

1,310

Government institutions

 

334

 

694

Prepaid expenses and others

 

693

 

797

 

1,104

 

2,801

v3.25.1
INVENTORY (Tables)
12 Months Ended
Dec. 31, 2024
INVENTORY  
Schedule of Inventory

December 31,

    

2024

    

2023

 U.S. dollars in thousands

Raw materials

513

828

Work in progress

308

233

Finished goods

 

2,830

 

3,328

 

3,651

 

4,389

v3.25.1
FIXED ASSETS (Tables)
12 Months Ended
Dec. 31, 2024
FIXED ASSETS  
Schedule of composition of assets and accumulated depreciation, grouped by major classifications

Cost

Accumulated depreciation

Depreciated balance

December 31

December 31

December 31

    

2024

    

2023

    

2024

    

2023

    

2024

    

2023

U.S. dollars in thousands

Office furniture and equipment (including computers)

 

1,068

 

1,059

 

988

 

956

 

80

 

103

Leasehold improvements

 

379

 

379

 

324

 

289

 

55

 

90

 

1,447

 

1,438

 

1,312

 

1,245

 

135

 

193

v3.25.1
LEASES (Tables)
12 Months Ended
Dec. 31, 2024
GENERAL  
Schedule of amounts recognized for leases

December 31,

    

2024

    

2023

U.S dollars in thousands

Right-of-use assets:

Properties

302

 

773

Vehicles

 

216

302

 

989

Lease liabilities:

  

 

  

Current

353

718

Non-current

3

 

455

356

 

1,173

For the year ended December 31, 2023, there were additions of $0.3 million. Decrease in lease liability during the year ended December 31, 2024, and 2023, were $0.2 million and $5.4 million respectively (with corresponding decrease in right of use asset in an amount of $0.2 million and $4.7 million respectively) resulting from early terminations of leases in 2024 and 2023.

In June 2023, the company terminated a U.S. office lease signed in March 2022 resulting in a $0.7 million gain. The termination, part of ongoing cost reduction efforts, followed a decrease in headcount, that reduced the Company's need for the office lease.

Amounts recognized in the consolidated statements of comprehensive loss:

Year Ended December 31,

    

2024

    

2023

Depreciation charge of right-of-use assets

Properties

470

 

798

Vehicles

51

478

521

1,276

Interest expense

55

367

Foreign exchange differences

7

3

Expenses relating to short-term leases and leases of low-value assets are immaterial.

The total cash outflow for leases in 2024 and 2023 was $0.7 million and $1.5 million respectively.

v3.25.1
INTANGIBLE ASSETS (Tables)
12 Months Ended
Dec. 31, 2024
INTANGIBLE ASSETS  
Schedule of intangible assets changes

 

Year Ended December 31, 

 

2024

    

2023

 

U.S. dollars in thousands

  

  

R&D assets:

Cost:

Balance at beginning of year

5,757

5,757

Balance at end of year

5,757

5,757

Accumulated amortization:

Balance at beginning of year

(179)

(148)

Amortization charges

(31)

(31)

Balance at end of year

(210)

(179)

5,547

5,578

Commercialization assets:

Cost:

Balance at beginning of year

11,788

89,373

Disposal during the year

(11,788)

(77,585)

Balance at end of year

11,788

Accumulated impairments and amortization:

Balance at beginning of year

(11,788)

(29,356)

Amortization and impairment charges

(514)

Disposal during the year

11,788

18,082

Balance at end of year

(11,788)

5,547

5,578

v3.25.1
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Tables)
12 Months Ended
Dec. 31, 2024
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES  
Schedule of accrued expenses and other current liabilities

December 31, 

    

2024

    

2023

U.S. dollars in thousands

Accrued expenses

 

2,698

 

3,765

Payable in respect to the Global Termination Agreement (see note 15(6)(b))

6,693

-

Employees and related liabilities

 

510

 

727

Government institutions

 

92

 

100

 

9,993

 

4,592

v3.25.1
ALLOWANCE FOR DEDUCTIONS FROM REVENUES (Tables)
12 Months Ended
Dec. 31, 2024
ALLOWANCE FOR DEDUCTIONS FROM REVENUES  
Schedule of movement of allowance for deductions from revenue

    

Rebates and patient discount programs

    

Product returns

    

Total

U.S. dollars in thousands

As of January 1, 2024

 

8,087

 

2,567

10,654

Increases

9,712

259

9,971

Decreases (utilized)

 

(10,423)

(2,500)

(12,923)

Adjustments

487

1,099

1,586

As of December 31, 2024

 

7,863

 

1,425

9,288

Rebates and patient discount programs

Product returns

Total

    

U.S. dollars in thousands

As of January 1, 2023

 

46,636

 

1,234

47,870

Increases

21,225

859

22,084

Decreases (utilized)

 

(60,498)

(2,969)

(63,467)

Adjustments

724

3,443

4,167

As of December 31, 2023

 

8,087

 

2,567

10,654

Rebates and patient discount programs

Product returns

Total

U.S. dollars in thousands

As of January 1, 2022

 

29,742

 

969

30,711

Increases

123,878

2,547

126,425

Decreases (utilized)

 

(108,531)

(2,192)

(110,723)

Adjustments

1,547

(90)

1,457

As of December 31, 2022

 

46,636

1,234

47,870

v3.25.1
SHARE CAPITAL (Tables)
12 Months Ended
Dec. 31, 2024
SHARE CAPITAL  
Schedule of composition of share capital

Number of shares

December 31, 

    

2024

    

2023

Authorized ordinary shares (1)

39,994,000,000

19,994,000,000

Authorized preferred shares (reserved)

6,000,000

6,000,000

Issued and paid ordinary shares

 

12,899,831,000

7,869,853,000

Issued and paid – in ADSs term (2)

1,290,000

787,000

v3.25.1
SHARE-BASED PAYMENTS (Tables)
12 Months Ended
Dec. 31, 2024
SHARE-BASED PAYMENTS  
Schedule of number of shares and weighted averages of exercise prices

Year Ended December 31, 

2024

2023

Weighted 

Weighted 

average of

average of

Number of 

exercise

Number of 

exercise

    

options

    

price ($)

    

options

    

price ($)

Outstanding at beginning of year

3,894

6,324.50

5,259

6,390.00

Exercised

 

 

Expired and forfeited

 

(1,275)

 

6,277.89

 

(1,365)

 

6,560.75

Outstanding at end of year

 

2,619

 

6,329.96

 

3,894

 

6,324.50

Exercisable at end of year

 

2,525

 

6,310.15

 

3,455

 

6,228.50

Schedule of expenses recognized in profit or loss

Year Ended December 31, 

2024

    

2023

    

2022

U.S. dollars in thousands

665

1,647

5,675

v3.25.1
NET REVENUES (Tables)
12 Months Ended
Dec. 31, 2024
NET REVENUES  
Schedule of net revenues

Year Ended December 31, 

    

2024

2023

2022

U.S dollars in thousands

Licensing revenues (1)

547

2,000

Sales of products (2)

7,496

6,530

59,800

 

 

8,043

 

6,530

61,800

v3.25.1
RESEARCH AND DEVELOPMENT EXPENSES (Tables)
12 Months Ended
Dec. 31, 2024
RESEARCH AND DEVELOPMENT EXPENSES.  
Schedule of research and development expenses

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

222

390

661

Professional services

 

708

 

605

1,210

Share-based payments

 

156

 

138

 

1,151

Clinical and pre-clinical trials

 

114

 

1,891

 

3,872

Intellectual property development

 

238

 

222

 

180

Other

 

150

 

282

 

205

 

1,588

 

3,528

 

7,279

v3.25.1
SELLING AND MARKETING EXPENSES (Tables)
12 Months Ended
Dec. 31, 2024
SELLING AND MARKETING EXPENSES  
Schedule of selling, marketing and business development expenses

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

3,076

9,656

19,235

Share-based payments

 

(41)

 

(51)

 

553

Professional services

 

1,913

 

3,056

 

6,596

Samples

54

836

Travel, Fleet, meals and related expenses

302

736

5,136

Office-related expenses

 

329

 

566

 

1,510

Other

 

371

 

739

 

1,576

 

5,950

 

14,756

 

35,442

v3.25.1
GENERAL AND ADMINISTRATIVE EXPENSES (Tables)
12 Months Ended
Dec. 31, 2024
GENERAL AND ADMINISTRATIVE EXPENSES  
Schedule of general and administrative expenses

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Payroll and related expenses

4,515

7,035

10,521

Share-based payments

 

550

 

1,560

 

3,971

Professional services and supply chain

 

3,118

 

5,391

 

10,787

Medical affairs

131

818

1,214

Office-related expenses

 

749

 

958

 

1,434

Other

 

504

 

457

 

659

 

9,567

 

16,219

 

28,586

v3.25.1
FINANCIAL INCOME (EXPENSES), net (Tables)
12 Months Ended
Dec. 31, 2024
FINANCIAL INCOME (EXPENSES), net  
Schedule of financial income (expenses), net

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S dollars in thousands

Financial income:

Fair value gains on derivative financial instruments

 

8,228

 

 

13,422

Gains on extinguishment of debt obligations by transfer of the rights in Movantik

20,585

Other Income

 

40

 

210

 

Interest from bank deposits

 

133

 

94

 

140

 

8,401

 

20,889

 

13,562

Financial expenses:

 

  

 

  

 

  

Interest for lease liabilities

55

367

430

Issuance cost in respect of warrants

1,497

2,034

958

Loss from changes in exchange rates

 

31

 

115

 

40

Fair value loss on derivative financial instruments

5,569

Loss from modification of warrants terms as part of a new issuance, see notes 17(b) and 17(d)

1,459

Interest expenses related to borrowing and payable in respect of intangible assets purchase

40,903

Other

 

473

 

61

 

56

 

2,056

 

9,605

 

42,387

Financial income (expenses), net

 

6,345

 

11,284

 

(28,825)

v3.25.1
SEGMENT INFORMATION (Tables)
12 Months Ended
Dec. 31, 2024
SEGMENT INFORMATION  
Schedule of segment profitability and reconciliation to consolidated net income (loss) and comprehensive income (loss)

Year Ended December 31, 

2024

2023

2022

    

U.S. dollars in thousands

Commercial Operations Segment Adjusted EBITDA

(5,864)

(20,173)

(16,595)

Research And Development Adjusted EBITDA

(5,129)

(8,165)

(12,420)

Financial income (expenses), net

6,346

11,284

(28,825)

Share-based compensation to employees and service providers

(665)

(1,647)

(5,675)

Depreciation

(588)

(1,445)

(2,136)

Amortization of intangible assets

(31)

(545)

(6,018)

Gain from early termination of lease

22

543

Other income (expenses)

(2,359)

44,064

Consolidated Comprehensive income (loss)

(8,268)

23,916

(71,669)

Supplementary information on material income or expense items included in the segment results:

Licensing revenues included in the Research And Development Adjusted EBITDA

547

2,000

Loss from Global Termination Agreement included in the Commercial Operations Segment, not included in the Adjusted EBITDA

(2,359)

Gain from the sale of Movantik®, included in the Commercial Operations Segment, not included in the Adjusted EBITDA

44,064

Schedule of percentages of total net revenues from major customers

Year Ended December 31, 

2024

2023

2022

Customer A

36%

30%

32%

Customer B

22%

28%

30%

Customer C

30%

37%

33%

v3.25.1
EARNINGS (LOSS) PER ORDINARY SHARE (Tables)
12 Months Ended
Dec. 31, 2024
EARNINGS (LOSS) PER ORDINARY SHARE  
Schedule of earnings (loss) per share

Year Ended December 31, 

    

2024

    

2023

    

2022

Earnings (Loss) (U.S. dollars in thousands)

(8,268)

23,916

(71,669)

Weighted average number of ordinary shares outstanding during the period (in thousands)

 

12,322,721

 

2,591,222

 

616,299

Basic earnings (loss) per share (U.S. dollars)

 

(0.00)

 

0.01

 

(0.12)

v3.25.1
RELATED PARTIES (Tables)
12 Months Ended
Dec. 31, 2024
RELATED PARTIES  
Schedule of key management compensation:

Year Ended December 31, 

    

2024

    

2023

    

2022

U.S. dollars in thousands

Key management compensation:

Salaries and other short-term employee benefits

 

1,030

 

1,189

 

1,486

Post-employment benefits

 

49

 

56

 

64

Share-based payments

 

205

 

407

 

1,041

Other long-term benefits

 

31

 

35

 

44

Schedule of balances with related parties

December 31, 

    

2024

    

2023

U.S. dollars in thousand

Current liabilities -

  

  

Credit balance in “accrued expenses and other current liabilities”

 

176

 

206

v3.25.1
GENERAL (Details) - shares
Aug. 20, 2024
Mar. 23, 2023
ADS    
General [Line Items]    
Number of Ordinary Shares Issued in Exchange of American Depository Receipts   10
New ADS Ratio [Member]    
General [Line Items]    
Number of Ordinary Shares Issued in Exchange of American Depository Receipts 10,000 400
v3.25.1
SUMMARY OF MATERIAL ACCOUNTING POLICIES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Accounting Policies [Line Items]    
Warrant liabilities $ 1,421 $ 741
IAS 1 Amendments | Warrants    
Accounting Policies [Line Items]    
Warrant liabilities   $ 741
Computer equipment    
Accounting Policies [Line Items]    
Depreciation rate, property, plant and equipment 33.00%  
Office furniture and equipment | Minimum    
Accounting Policies [Line Items]    
Depreciation rate, property, plant and equipment 8.00%  
Office furniture and equipment | Maximum    
Accounting Policies [Line Items]    
Depreciation rate, property, plant and equipment 15.00%  
v3.25.1
CRITICAL ACCOUNTING ESTIMATES AND JUDGMENTS (Details)
12 Months Ended
Dec. 31, 2024
USD ($)
Disclosure of significant unobservable inputs used in fair value measurement of assets [line items]  
Discount rate applied to risk-adjusted cash flows 18.10%
Intangible R&D Assets [member]  
Disclosure of significant unobservable inputs used in fair value measurement of assets [line items]  
Impairment loss $ 0
v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2024
USD ($)
item
Dec. 31, 2023
USD ($)
Financial instruments    
Number of major U.S. wholesalers. | item 3  
Trade receivable member | Impairment    
Financial instruments    
Trade receivables | $ $ 0 $ 0
Maximum    
Financial instruments    
Maturity periods for cash balances in highly-rated bank deposits 1 year  
Market risk [member] | U.S. dollar    
Financial instruments    
Percentage of currency stronger against the NIS 5.00%  
v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT - By contractual maturities (Details) - USD ($)
Dec. 31, 2024
Dec. 31, 2023
Financial instruments    
Contractual cash flows $ 12,912,000 $ 10,946,000
Carrying amount 12,018,000 9,583,000
Less than 1 year    
Financial instruments    
Contractual cash flows 11,526,000 8,636,000
2-5 years    
Financial instruments    
Contractual cash flows 140,000 757,000
More than five years    
Financial instruments    
Contractual cash flows 1,246,000 1,553,000
Accounts payable    
Financial instruments    
Contractual cash flows 1,168,000 3,278,000
Carrying amount 1,168,000 3,278,000
Accounts payable | Less than 1 year    
Financial instruments    
Contractual cash flows 1,168,000 3,278,000
Lease liabilities    
Financial instruments    
Contractual cash flows 368,000 1,241,000
Carrying amount 356,000 1,173,000
Lease liabilities | Less than 1 year    
Financial instruments    
Contractual cash flows 365,000 766,000
Lease liabilities | 2-5 years    
Financial instruments    
Contractual cash flows 3,000 475,000
Accrued expenses and other current liabilities    
Financial instruments    
Contractual cash flows 9,993,000 4,592,000
Carrying amount 9,993,000 4,592,000
Accrued expenses and other current liabilities | Less than 1 year    
Financial instruments    
Contractual cash flows 9,993,000 4,592,000
Royalty obligation    
Financial instruments    
Contractual cash flows 1,383,000 1,835,000
Carrying amount 500,000 540,000
Royalty obligation | 2-5 years    
Financial instruments    
Contractual cash flows 137,000 282,000
Royalty obligation | More than five years    
Financial instruments    
Contractual cash flows $ 1,246,000 $ 1,553,000
v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT - DERIVATIVE LIABILITIES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Disclosure of detailed information about financial instruments [line items]      
Balance at beginning of the period $ 20,978    
Fair value adjustments and recognition of day 1 loss recognized in profit or loss (8,228)   $ (13,422)
Balance at the end of the period 22,726 $ 20,978  
Derivatives      
Disclosure of detailed information about financial instruments [line items]      
Unrecognized Day 1 Loss 800    
Level 3 | At fair value | Derivatives      
Disclosure of detailed information about financial instruments [line items]      
Balance at beginning of the period 741 2,623  
Initial recognition of financial liability 9,860 10,932  
Initial Recognition of Unrecognized Day 1 Loss (952)    
Exercise of financial liability   (18,383)  
Fair value adjustments and recognition of day 1 loss recognized in profit or loss (8,228) 5,569  
Balance at the end of the period $ 1,421 $ 741 $ 2,623
v3.25.1
FINANCIAL INSTRUMENTS AND FINANCIAL RISK MANAGEMENT - Reconciliation of liabilities arising from financing activities (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Payables In Respect To The Global Termination Agreement [member]      
Disclosure of reconciliation of liabilities arising from financing activities [line items]      
Additions $ 11,443    
Decrease during the year (4,750)    
Ending balance 6,693    
Borrowing      
Disclosure of reconciliation of liabilities arising from financing activities [line items]      
Beginning balance   $ 115,216 $ 83,620
Principal and interest payments (includes credits)     (7,507)
Decrease during the year   (115,216)  
Interest expense     39,103
Ending balance     115,216
Payable in respect of intangible assets purchase      
Disclosure of reconciliation of liabilities arising from financing activities [line items]      
Beginning balance   11,157 20,480
Principal and interest payments (includes credits)   (6,555) (11,123)
Decrease during the year   (4,602)  
Interest expense     1,800
Ending balance     11,157
Lease liabilities      
Disclosure of reconciliation of liabilities arising from financing activities [line items]      
Beginning balance 1,173 7,475 4,192
Principal and interest payments (includes credits) (691) (1,529) (2,010)
Additions   270 5,003
Decrease during the year (188) (5,413)  
Interest expense 55 367 430
Foreign exchange movement 7 3 (140)
Ending balance $ 356 $ 1,173 $ 7,475
v3.25.1
CASH AND CASH EQUIVALENTS (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
CASH AND CASH EQUIVALENTS.        
Cash in bank $ 1,882 $ 5,569    
Short-term bank deposits 2,735      
Cash and cash equivalents $ 4,617 $ 5,569 $ 19,968 $ 29,474
v3.25.1
PREPAID EXPENSES AND OTHER RECEIVABLES (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
PREPAID EXPENSES AND OTHER RECEIVABLES    
Advance to suppliers $ 77 $ 1,310
Government institutions 334 694
Prepaid expenses and others 693 797
Total prepaid expenses and other receivables $ 1,104 $ 2,801
v3.25.1
INVENTORY (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Disclosure of information related to Inventory [Line Item]      
Raw materials $ 513 $ 828  
Work in progress 308 233  
Finished goods 2,830 3,328  
Total inventory 3,651 4,389  
Cost of sales [member]      
Disclosure of information related to Inventory [Line Item]      
Inventory recognized as part of cost of revenues 3,400 4,400 $ 9,700
Inventory write-down $ 200 $ 1,300 $ 2,400
v3.25.1
FIXED ASSETS (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Fixed assets    
Fixed assets $ 135 $ 193
Cost    
Fixed assets    
Fixed assets 1,447 1,438
Accumulated amortization    
Fixed assets    
Fixed assets (1,312) (1,245)
Office furniture and equipment (including computers)    
Fixed assets    
Fixed assets 80 103
Office furniture and equipment (including computers) | Cost    
Fixed assets    
Fixed assets 1,068 1,059
Office furniture and equipment (including computers) | Accumulated amortization    
Fixed assets    
Fixed assets (988) (956)
Leasehold improvements    
Fixed assets    
Fixed assets 55 90
Leasehold improvements | Cost    
Fixed assets    
Fixed assets 379 379
Leasehold improvements | Accumulated amortization    
Fixed assets    
Fixed assets $ (324) $ (289)
v3.25.1
LEASES (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Jun. 30, 2023
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Right-of-use assets:        
Right-of-use assets   $ 302 $ 989  
Lease liabilities:        
Current   353 718  
Non-current   3 455  
Lease liabilities   356 1,173  
Additions to right-of-use assets     300  
Additions to lease liabilities     300  
Decrease in lease liabilities   200 5,400  
Decrease in right o fuse assets   166 4,697  
Depreciation charge of right-of-use assets   521 1,276  
Interest expense   55 367 $ 430
Foreign exchange differences   7 3  
Cash outflow for leases   700 1,500  
Gain On Termination Of Operating Lease Agreement $ 700      
Properties        
Right-of-use assets:        
Right-of-use assets   302 773  
Lease liabilities:        
Depreciation charge of right-of-use assets   470 798  
Vehicles        
Right-of-use assets:        
Right-of-use assets     216  
Lease liabilities:        
Depreciation charge of right-of-use assets   $ 51 $ 478  
v3.25.1
INTANGIBLE ASSETS - Changes in Assets (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Reconciliation of changes in intangible assets    
Balance at beginning of year $ 5,578  
Balance at end of year 5,547 $ 5,578
R&D assets    
Reconciliation of changes in intangible assets    
Balance at beginning of year 5,578  
Balance at end of year 5,547 5,578
R&D assets | Cost    
Reconciliation of changes in intangible assets    
Balance at beginning of year 5,757 5,757
Balance at end of year 5,757 5,757
R&D assets | Accumulated amortization    
Reconciliation of changes in intangible assets    
Balance at beginning of year (179) (148)
Amortization charges (31) (31)
Balance at end of year (210) (179)
Commercialization assets | Cost    
Reconciliation of changes in intangible assets    
Balance at beginning of year 11,788 89,373
Disposal during the year (11,788) (77,585)
Balance at end of year   11,788
Commercialization assets | Accumulated impairments and amortization    
Reconciliation of changes in intangible assets    
Balance at beginning of year (11,788) (29,356)
Disposal during the year $ 11,788 18,082
Amortization and impairment charges   (514)
Balance at end of year   $ (11,788)
v3.25.1
INTANGIBLE ASSETS - Narrative (Details)
12 Months Ended
Dec. 31, 2024
Talicia  
Reconciliation of changes in intangible assets  
Useful life of assets (in years) 15 years
v3.25.1
LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT (Details) - USD ($)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
LIABILITY FOR EMPLOYEE RIGHTS UPON RETIREMENT      
Defined contribution plans expense $ 156,000 $ 206,000 $ 261,000
v3.25.1
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES    
Accrued expenses $ 2,698 $ 3,765
Payable in respect to the Global Termination Agreement (see note 15(6)(b)) 6,693  
Employees and related liabilities 510 727
Government institutions 92 100
Accrued expenses and other current liabilities $ 9,993 $ 4,592
v3.25.1
ALLOWANCE FOR DEDUCTIONS FROM REVENUES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Disclosure of other provisions [line items]      
Balance at Beginning of period $ 10,654 $ 47,870 $ 30,711
Increases 9,971 22,084 126,425
Decreases (Utilized) (12,923) (63,467) (110,723)
Adjustments 1,586 4,167 1,457
Balance at end of period 9,288 10,654 47,870
Rebates and patient discount programs      
Disclosure of other provisions [line items]      
Balance at Beginning of period 8,087 46,636 29,742
Increases 9,712 21,225 123,878
Decreases (Utilized) (10,423) (60,498) (108,531)
Adjustments 487 724 1,547
Balance at end of period 7,863 8,087 46,636
Product returns      
Disclosure of other provisions [line items]      
Balance at Beginning of period 2,567 1,234 969
Increases 259 859 2,547
Decreases (Utilized) (2,500) (2,969) (2,192)
Adjustments 1,099 3,443 (90)
Balance at end of period $ 1,425 $ 2,567 $ 1,234
v3.25.1
COMMITMENTS - Agreements to Purchase Intellectual Property (Details)
Mar. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Aug. 11, 2010
USD ($)
item
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2018
USD ($)
Commitments            
Noncurrent Royalty Obligation       $ 500,000 $ 540,000  
Australian Asset Purchase Agreement            
Commitments            
Number of therapeutic candidates | item     3      
Upfront initial payment per agreement     $ 500,000      
Aggregate payments made       1,500,000    
Australian Asset Purchase Agreement | Minimum            
Commitments            
Percentage of revenues to be paid in the future     7.00%      
Australian Asset Purchase Agreement | Maximum            
Commitments            
Percentage of revenues to be paid in the future     20.00%      
German Publicly Traded Company Arrangement            
Commitments            
Upfront initial payment per agreement   $ 1,000,000        
German Publicly Traded Company Arrangement | Maximum            
Commitments            
Royalties percentage   30.00%        
U.S. Private Company Arrangement            
Commitments            
Upfront initial payment per agreement $ 1,500,000          
Milestones to be paid 2,000,000          
Noncurrent Royalty Obligation       500,000 $ 540,000 $ 500,000
Aggregate payments made       $ 3,000,000    
U.S. Private Company Arrangement | Maximum            
Commitments            
Milestones to be paid $ 2,000,000          
v3.25.1
COMMITMENTS - Movantik Acquisition (Details) - USD ($)
$ in Thousands
Apr. 01, 2020
Dec. 31, 2024
Dec. 31, 2023
Disclosure of detailed information about intangible assets [line items]      
Intangible assets   $ 5,547 $ 5,578
Movantik      
Disclosure of detailed information about intangible assets [line items]      
Intangible assets $ 65,000    
Useful life of assets (in years) 12 years 6 months    
v3.25.1
COMMITMENTS - DSI Agreement (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Jul. 15, 2024
Jul. 01, 2020
Feb. 28, 2023
Dec. 31, 2024
Dec. 31, 2023
Disclosure of classes of share capital [line items]          
Amount held in escrow account         $ 790
Proceeds received following global termination agreement $ 9,900        
Liabilities       $ 22,726 20,978
Loss From Global Termination Agreement 2,300     (2,359)  
Restricted Cash And Cash Equivalent released. 700        
Movantik Acquisition Co, Valinor Pharma, LLC, and HCR Redhill SPV, LLC          
Disclosure of classes of share capital [line items]          
Liabilities $ 12,200        
Movantik          
Disclosure of classes of share capital [line items]          
Amount held in escrow account     $ 16,000   $ 800
Gains On Disposals Of Movantik       35,500  
Gains From The Debt Extinguishment.       20,600  
Cash Payment For Rights To Movantik Used To Determine Fair Value       $ 95,000  
Paid transition services period     9 months    
Movantik | DSI          
Disclosure of classes of share capital [line items]          
Contractual capital commitments   $ 15,100      
Payments For Commercialization Of Movantik   10,100      
Payment Commitment Assumed By HCRM   $ 5,000      
v3.25.1
COMMITMENTS - License Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Feb. 24, 2025
Dec. 31, 2024
Apr. 30, 2022
Mar. 31, 2022
Dec. 31, 2024
Dec. 31, 2022
Aug. 31, 2024
Sep. 02, 2022
Disclosure of detailed information about intangible assets [line items]                
Upfront payments received $ 100              
Licensing revenue         $ 547 $ 2,000    
Kukbo Co. Ltd. | Exclusive license agreement                
Disclosure of detailed information about intangible assets [line items]                
Upfront payments received       $ 1,500        
Default amount               $ 1,500
Kukbo Co. Ltd. | Subscription agreement                
Disclosure of detailed information about intangible assets [line items]                
Default amount               $ 5,000
Kukbo Co. Ltd. | Exclusive license and subscription agreement                
Disclosure of detailed information about intangible assets [line items]                
Principal Amount Awarded And Due To The Company   $ 6,500     6,500      
Interest rate on award   9.00%            
Interest Amount Awarded And Due To The Company   $ 1,800     1,800      
Attorney's fees recoverable   1,800     $ 1,800      
Gaelan | Talicia                
Disclosure of detailed information about intangible assets [line items]                
Upfront payments received     $ 2,000          
maximum eligible milestone payments             $ 500  
Licensing revenue           $ 2,000    
Haynes and Boone LLP | Contingency fee agreement                
Disclosure of detailed information about intangible assets [line items]                
Collection period payment limit from outcome date         6 months      
Fees payable   $ 1,100     $ 1,100      
v3.25.1
INCOME TAX (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax [Line Items]    
Deductible temporary differences $ 3 $ 6
Israel    
Income Tax [Line Items]    
Corporate tax rate 23.00%  
Israel | No Expiration [member]    
Income Tax [Line Items]    
Net operating losses $ 350  
U.S.    
Income Tax [Line Items]    
Corporate tax rate 21.00%  
Net operating losses $ 45  
v3.25.1
SHARE CAPITAL (Details)
₪ / shares in Units, $ / shares in Units, $ in Thousands
5 Months Ended 12 Months Ended
Apr. 10, 2025
USD ($)
$ / shares
Aug. 20, 2024
shares
Aug. 19, 2024
shares
Apr. 03, 2024
USD ($)
$ / shares
shares
Jan. 26, 2024
USD ($)
$ / shares
shares
Sep. 28, 2023
USD ($)
$ / shares
shares
Jul. 25, 2023
USD ($)
$ / shares
shares
Apr. 03, 2023
USD ($)
$ / shares
shares
Mar. 23, 2023
shares
Mar. 22, 2023
shares
Nov. 29, 2023
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
shares
Dec. 31, 2022
USD ($)
Dec. 31, 2024
₪ / shares
shares
Mar. 21, 2024
ILS (₪)
₪ / shares
shares
Disclosure of classes of share capital [line items]                                
Issued and paid ordinary shares                         7,869,853,000   12,899,831,000  
Number of shares issued             52,077                  
Proceeds from issuance | $       $ 1,250               $ 8,263 $ 13,959 $ 23,806    
Offering expenses | $       $ 100                        
Financial expense | $                       2,056 $ 9,605 $ 42,387    
Proceeds from issuance of shares | $ $ 2,200                              
Authorised Share Capital | ₪                               ₪ 400,000,000
Purchase price (per share) | $ / shares $ 4.96                              
Placement Agent [Member]                                
Disclosure of classes of share capital [line items]                                
Class of warrant or right, number of securities called by warrants or rights         24,000                      
Series A unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares               $ 45                
Warrants term               5 years                
Class of warrant or right, number of securities called by warrants or rights               60,000                
Warrants, exercisable term               6 months                
Placement agent warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares               $ 125                
Class of warrant or right, number of securities called by warrants or rights               3,600                
Warrants, exercisable term               5 years                
Maximum                                
Disclosure of classes of share capital [line items]                                
Gross consideration | $ $ 3,500                              
ADS                                
Disclosure of classes of share capital [line items]                                
Number of shares issued                         1,893      
Ordinary shares                                
Disclosure of classes of share capital [line items]                                
Par value per share | ₪ / shares                               ₪ 0.01
Authorized ordinary shares                         19,994,000,000   39,994,000,000 39,994,000,000
Ordinary shares | ADS                                
Disclosure of classes of share capital [line items]                                
Number of ordinary shares issued in exchange of American depository receipts   10,000             400 10            
Preferred shares                                
Disclosure of classes of share capital [line items]                                
Par value per share | ₪ / shares                               ₪ 0.01
Authorized ordinary shares                         6,000,000   6,000,000 6,000,000
ADS                                
Disclosure of classes of share capital [line items]                                
Issued and paid ordinary shares                         787,000   1,290,000  
Number of shares issued       85,779 400,000 10,325                 17,218  
Share price | $ / shares       $ 14.57 $ 20                      
Exercise price of warrants | $ / shares         $ 25                      
Warrants term         5 years                      
Class of warrant or right, number of securities called by warrants or rights         400,000                      
Proceeds from issuance | $         $ 8,000                      
Offering expenses | $         900                      
ADS                                
Disclosure of classes of share capital [line items]                                
Number of ordinary shares issued in exchange of American depository receipts                 10              
Exercise price of warrants | $ / shares       $ 18.75                        
Warrants term       5 years                        
Class of warrant or right, number of securities called by warrants or rights       85,779                        
ADS | Series A unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares               $ 33.75                
Class of warrant or right, number of securities called by warrants or rights               60,000                
Proceeds from issuance of shares | $               $ 2,000                
ADS | Ordinary shares | ADS                                
Disclosure of classes of share capital [line items]                                
Number of ordinary shares issued in exchange of American depository receipts     400                          
Underwritten public offering                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 45 $ 115.76                  
Class of warrant or right, number of securities called by warrants or rights           38,873 38,873                  
Registered Direct Offering                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 11.75 $ 45                  
Proceeds from issuance | $           $ 2,000 $ 1,800 6,000                
Offering expenses | $           $ 200 $ 400 $ 700                
Registered Direct Offering | Pre-funded warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares             $ 0.025 $ 0.025                
Registered Direct Offering | Unregistered Private Warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 45 $ 118.75                  
Class of warrant or right, number of securities called by warrants or rights           13,204 13,204                  
Registered Direct Offering | Series A unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 45                    
Class of warrant or right, number of securities called by warrants or rights           60,000                    
Registered Direct Offering | Series B unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 45   $ 100                
Warrants term               9 months                
Class of warrant or right, number of securities called by warrants or rights           60,000   60,000                
Registered Direct Offering | New Unregistered Warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 11.75                    
Warrants term           5 years                    
Class of warrant or right, number of securities called by warrants or rights           344,154                    
Warrants, exercisable term           18 months                    
Registered Direct Offering | First portion of placement agent warrants                                
Disclosure of classes of share capital [line items]                                
Class of warrant or right, number of securities called by warrants or rights             3,125                  
Warrants, exercisable term             5 years                  
Registered Direct Offering | Second portion of placement agent warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares             $ 42.19                  
Warrants term             4 years 8 months 12 days                  
Number of warrants to purchase shares             3,600                  
Registered Direct Offering | Placement agent warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares           $ 14.69                    
Warrants term           5 years                    
Proceeds from warrant exercises | $                     $ 4,000          
Registered Direct Offering | ADS | First portion of placement agent warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares             $ 42.19                  
Registered Direct Offering | ADS                                
Disclosure of classes of share capital [line items]                                
Number of shares issued               60,000                
Exercise price of warrants | $ / shares               $ 1,480                
Class of warrant or right, number of securities called by warrants or rights               13,204                
Registered Direct Offering | ADS | Unregistered Private Warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares               $ 118.75                
Warrants term               5 years                
Registered Direct Offering | ADS | Series A unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares             33.75 $ 118.75                
Warrants term               5 years                
Class of warrant or right, number of securities called by warrants or rights               60,000                
Registered Direct Offering | ADS | Series B unregistered private warrants                                
Disclosure of classes of share capital [line items]                                
Exercise price of warrants | $ / shares             $ 45 $ 100                
Class of warrant or right, number of securities called by warrants or rights               60,000                
Ordinary shares                                
Disclosure of classes of share capital [line items]                                
Par value per share | ₪ / shares                             ₪ 0.01  
Equity component                                
Disclosure of classes of share capital [line items]                                
Gross consideration | $       $ 350                        
Warrants                                
Disclosure of classes of share capital [line items]                                
Offering expenses | $         $ 900                      
Gross consideration | $       $ 900                        
Financial expense | $                       $ 900        
Warrants | ADS | Minimum                                
Disclosure of classes of share capital [line items]                                
Risk-free interest rate                       4.27%        
Average standard deviation                       131.60%        
Warrants | ADS | Maximum                                
Disclosure of classes of share capital [line items]                                
Risk-free interest rate                       4.34%        
Average standard deviation                       148.37%        
v3.25.1
SHARE-BASED PAYMENTS (Details)
$ in Millions
12 Months Ended
Sep. 18, 2024
USD ($)
shares
Jun. 24, 2024
USD ($)
shares
installment
Jul. 01, 2023
USD ($)
shares
installment
Dec. 31, 2024
USD ($)
shares
Option
Dec. 31, 2023
USD ($)
Option
shares
Disclosure of terms and conditions of share-based payment arrangement [line items]          
Maximum Amount Of Options Company Allowed To Allocate       2,717,305,440  
Maximum Amount Of ADS Company Allowed To Allocate       271,730  
Number of RSUs granted       57,080 7,500
Number of options cancelled | Option       1,275 1,365
Each option exercisable into number of ordinary shares, ratio | Option       2,525 3,455
RSUs          
Disclosure of terms and conditions of share-based payment arrangement [line items]          
Number of RSUs granted   41,760 7,500    
Fair value on date of grant | $   $ 0.4 $ 0.2    
Number of equal quarterly vesting installments | installment   8 12    
Vesting period   2 years 3 years    
Stock Options and RSUs          
Disclosure of terms and conditions of share-based payment arrangement [line items]          
Share options forfeited       2,584 2,720
Shares forfeited, reversed expenses | $       $ 0.3 $ 1.6
Directors And Chief Executive Officer. [member] | RSUs          
Disclosure of terms and conditions of share-based payment arrangement [line items]          
Number of RSUs granted 15,320        
Fair value on date of grant | $ $ 0.1        
v3.25.1
SHARE-BASED PAYMENTS - Number of Options and Weighted Averages of Exercise Prices (Details)
12 Months Ended
Dec. 31, 2024
Option
$ / shares
Dec. 31, 2024
Option
$ / shares
Dec. 31, 2024
shares
Option
$ / shares
Dec. 31, 2023
Option
$ / shares
Dec. 31, 2023
Option
$ / shares
Dec. 31, 2023
Option
shares
$ / shares
SHARE-BASED PAYMENTS            
Number of options, outstanding at beginning of year 3,894   3,894 5,259    
Number of options, expired and forfeited | Option (1,275)     (1,365)    
Number of options, outstanding at end of year 2,619   2,619 3,894   3,894
Number of options, exercisable at end of year | Option 2,525 2,525 2,525 3,455 3,455 3,455
Weighted average of exercise price, outstanding at beginning of year   $ 6,324.5     $ 6,390  
Weighted average of exercise price, expired and forfeited   6,277.89     6,560.75  
Weighted average of exercise price, outstanding at end of year   6,329.96     6,324.5  
Weighted average of exercise price, exercisable at end of year $ 6,310.15 $ 6,310.15 $ 6,310.15 $ 6,228.5 $ 6,228.5 $ 6,228.5
v3.25.1
SHARE-BASED PAYMENTS - Number of RSUs (Details) - shares
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
SHARE-BASED PAYMENTS    
Number of RSUs, Outstanding at beginning of year 7,121 3,646
Number of RSUs, Exercised (23,938) (2,658)
Number of RSUs, Expired and forfeited (2,497) (1,367)
Number of RSUs, Granted 57,080 7,500
Number of RSUs, Outstanding at end of year 37,766 7,121
v3.25.1
SHARE-BASED PAYMENTS - Information About Exercise Price and Remaining Useful Life of Outstanding Options (Details)
12 Months Ended
Dec. 31, 2024
Option
Dec. 31, 2023
Option
Dec. 31, 2024
shares
Dec. 31, 2024
$ / shares
Dec. 31, 2023
shares
Dec. 31, 2023
$ / shares
Dec. 31, 2022
Option
Disclosure of number and weighted average remaining contractual life of outstanding share options [line items]              
Number of options outstanding at end of Year 2,619 3,894 2,619   3,894   5,259
Weighted average of remaining useful life 5 years 15 days 5 years 2 months          
Minimum              
Disclosure of number and weighted average remaining contractual life of outstanding share options [line items]              
Exercise price range       $ 1,670   $ 1,670  
Maximum              
Disclosure of number and weighted average remaining contractual life of outstanding share options [line items]              
Exercise price range       $ 10,370   $ 10,900  
v3.25.1
SHARE-BASED PAYMENTS - Expenses Recognized in Profit or Loss (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
SHARE-BASED PAYMENTS      
Expenses recognized in profit or loss $ 665 $ 1,647 $ 5,675
Unrecognized compensation expenses $ 200    
v3.25.1
NET REVENUES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Revenues      
Licensing revenue $ 547   $ 2,000
Sale of products 7,496 $ 6,530 59,800
Revenue 8,043 6,530 61,800
Talicia      
Revenues      
Revenue 8,400 9,100 7,700
Talicia | Gaelan Medical Trade LLC      
Revenues      
Licensing revenue     2,000
Movantik      
Revenues      
Revenue     $ 52,100
Contra Revenue For Movantik $ (900) $ (2,600)  
v3.25.1
RESEARCH AND DEVELOPMENT EXPENSES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Research And Development Expenses Net [Line Items]      
Research and development expenses $ 1,588 $ 3,528 $ 7,279
Payroll and related expenses      
Research And Development Expenses Net [Line Items]      
Research and development expenses 222 390 661
Professional services      
Research And Development Expenses Net [Line Items]      
Research and development expenses 708 605 1,210
Share-based payments      
Research And Development Expenses Net [Line Items]      
Research and development expenses 156 138 1,151
Clinical and pre-clinical trials      
Research And Development Expenses Net [Line Items]      
Research and development expenses 114 1,891 3,872
Intellectual property development      
Research And Development Expenses Net [Line Items]      
Research and development expenses 238 222 180
Other      
Research And Development Expenses Net [Line Items]      
Research and development expenses $ 150 $ 282 $ 205
v3.25.1
SELLING AND MARKETING EXPENSES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses $ 5,950 $ 14,756 $ 35,442
Payroll and related expenses      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses 3,076 9,656 19,235
Share-based payments      
Selling Marketing And Business Development Expenses [Line Items]      
Selling And Marketing Expenses Share Based Payments (41) (51) 553
Professional services      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses 1,913 3,056 6,596
Samples      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses   54 836
Travel, Fleet, meals and related expenses      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses 302 736 5,136
Office-related expenses      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses 329 566 1,510
Other      
Selling Marketing And Business Development Expenses [Line Items]      
Selling, and marketing expenses $ 371 $ 739 $ 1,576
v3.25.1
GENERAL AND ADMINISTRATIVE EXPENSES (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
General And Administrative Expense [Line Items]      
General and administrative expenses $ 9,567 $ 16,219 $ 28,586
Payroll and related expenses      
General And Administrative Expense [Line Items]      
General and administrative expenses 4,515 7,035 10,521
Share-based payments      
General And Administrative Expense [Line Items]      
General and administrative expenses 550 1,560 3,971
Professional services and supply chain      
General And Administrative Expense [Line Items]      
General and administrative expenses 3,118 5,391 10,787
Medical affairs      
General And Administrative Expense [Line Items]      
General and administrative expenses 131 818 1,214
Office-related expenses      
General And Administrative Expense [Line Items]      
General and administrative expenses 749 958 1,434
Other      
General And Administrative Expense [Line Items]      
General and administrative expenses $ 504 $ 457 $ 659
v3.25.1
FINANCIAL INCOME (EXPENSES), net (Details) - USD ($)
$ in Thousands
12 Months Ended
Jul. 15, 2024
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
FINANCIAL INCOME (EXPENSES), net        
Fair value gains on derivative financial instruments   $ 8,228   $ 13,422
Gains on extinguishment of debt obligations by transfer of the rights in Movantik     $ 20,585  
Other income   40 210  
Interest from bank deposits   133 94 140
Financial income   8,401 20,889 13,562
Interest for lease liabilities.   55 367 430
Issuance cost in respect of warrants   1,497 2,034 958
Loss from changes in exchange rates   31 115 40
Fair value loss on derivative financial instruments.     5,569  
Loss from modification of warrants terms as part of a new issuance, see notes 17(b) and 17(d)     1,459  
loss from global termination agreement (see note 15 (6)) $ 2,300 (2,359)    
Interest expenses related to borrowing and payable in respect of intangible assets purchase       40,903
Other   473 61 56
Financial expenses   2,056 9,605 42,387
Financial income (expenses), net   $ 6,345 $ 11,284 $ (28,825)
v3.25.1
SEGMENT INFORMATION - Segment profitability and reconciliation to consolidated net income (loss) (Details) - USD ($)
$ in Thousands
12 Months Ended
Jul. 15, 2024
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
SEGMENT INFORMATION        
Commercial Operations Segment Adjusted EBITDA   $ (5,864) $ (20,173) $ (16,595)
Research And Development Adjusted EBITDA   (5,129) (8,165) (12,420)
Financial income (expenses), net   6,345 11,284 (28,825)
Share-based compensation to employees and service providers   (665) (1,647) (5,675)
Depreciation   (588) (1,445) (2,136)
Amortization of intangible assets   (31) (545) (6,018)
Gain from early termination of lease   22 543  
Other income (expenses)   (2,359) 44,064  
Comprehensive income (loss)   (8,268) 23,916 (71,669)
Supplementary information on material income or expense items included in the segment results:        
Licensing revenues included in the Research And Development Adjusted EBITDA   547   $ 2,000
Loss from Global Termination Agreement included in the Commercial Operations Segment, not included in the Adjusted EBITDA $ 2,300 $ (2,359)    
Gain from the sale of Movantik, included in the Commercial Operations Segment, not included in the Adjusted EBITDA     $ 44,064  
v3.25.1
SEGMENT INFORMATION - Major Customers and Segment Assets (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Disclosure of major customers      
Revenue $ 8,043 $ 6,530 $ 61,800
UAE | Gaelan      
Disclosure of major customers      
Revenue $ 1,000   $ 2,000
Outside the united states      
Disclosure of major customers      
Revenue   $ 0  
Minimum      
Disclosure of major customers      
Payment Terms For Customers 31 days    
Maximum      
Disclosure of major customers      
Payment Terms For Customers 68 days    
Customer A      
Disclosure of major customers      
Percentage of revenue 36.00% 30.00% 32.00%
Customer B      
Disclosure of major customers      
Percentage of revenue 22.00% 28.00% 30.00%
Customer C      
Disclosure of major customers      
Percentage of revenue 30.00% 37.00% 33.00%
v3.25.1
SEGMENT INFORMATION - Assets by geographic location (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Disclosure of geographical areas [line items]    
Non-current assets $ 6,132 $ 6,907
Intangible assets 5,547 5,578
Right-of-use assets 302 989
Israel    
Disclosure of geographical areas [line items]    
Non-current assets 6,100 6,400
Intangible assets 5,500 5,600
Right-of-use assets $ 300 600
U.S.    
Disclosure of geographical areas [line items]    
Non-current assets   500
Right-of-use assets   $ 400
v3.25.1
EARNINGS (LOSS) PER ORDINARY SHARE - Basic (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Basic      
Earnings (Loss) (U.S. dollars in thousands) $ (8,268) $ 23,916 $ (71,669)
Weighted average number of ordinary shares outstanding during the period (in thousands) 12,322,721 2,591,222 616,299
Basic earnings (loss) per share (U.S. dollars) $ 0 $ 0.01 $ (0.12)
v3.25.1
EARNINGS (LOSS) PER ORDINARY SHARE - Diluted (Details)
12 Months Ended
Dec. 31, 2024
shares
Warrants  
Disclosure of instruments with potential future dilutive effect not included in calculation of diluted earnings per share [line items]  
Potentially dilutive ordinary shares. 5,606,626,800
Share options [member]  
Disclosure of instruments with potential future dilutive effect not included in calculation of diluted earnings per share [line items]  
Potentially dilutive ordinary shares. 26,190,400
Restricted share units [member]  
Disclosure of instruments with potential future dilutive effect not included in calculation of diluted earnings per share [line items]  
Potentially dilutive ordinary shares. 377,659,600
v3.25.1
RELATED PARTIES - Key Management Compensation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
RELATED PARTIES      
Salaries and other short-term employee benefits $ 1,030 $ 1,189 $ 1,486
Post-employment benefits 49 56 64
Share-based payments 205 407 1,041
Other long-term benefits $ 31 $ 35 $ 44
v3.25.1
RELATED PARTIES - Balances with Related Parties (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Current liabilities    
Credit balance in "accrued expenses and other current liabilities" $ 176 $ 206
v3.25.1
EVENTS SUBSEQUENT TO DECEMEBER 31, 2024 (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Apr. 10, 2025
Feb. 24, 2025
Apr. 03, 2024
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Jul. 25, 2023
Disclosure of non-adjusting events after reporting period [line items]              
Number of shares issued             52,077
Proceeds from issue of ordinary shares     $ 1,250 $ 8,263 $ 13,959 $ 23,806  
Number of ADSs shares sold 453,345            
Purchase price (per share) $ 4.96            
Proceeds from issuance of shares $ 2,200            
Upfront payments received   $ 100          
Maximum              
Disclosure of non-adjusting events after reporting period [line items]              
Gross consideration $ 3,500            
maximum eligible milestone payments   $ 60,000