ILLUMINA, INC., 10-K filed on 2/12/2025
Annual Report
v3.25.0.1
Cover Page - USD ($)
$ in Billions
12 Months Ended
Dec. 29, 2024
Feb. 07, 2025
Jun. 30, 2024
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 29, 2024    
Current Fiscal Year End Date --12-29    
Document Transition Report false    
Entity File Number 001-35406    
Entity Registrant Name Illumina, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 33-0804655    
Entity Address, Address Line One 5200 Illumina Way    
Entity Address, City or Town San Diego    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 92122    
City Area Code 858    
Local Phone Number 202-4500    
Title of 12(b) Security Common Stock, $0.01 par value    
Trading Symbol ILMN    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Common Stock, Shares Outstanding   158,400,000  
Entity Public Float     $ 14.7
Documents Incorporated by Reference
Portions of the registrant’s proxy statement for the 2025 annual meeting of stockholders are incorporated by reference into Items 10 through 14 of Part III of this Report.
   
Entity Central Index Key 0001110803    
Document Fiscal Year Focus 2024    
Document Fiscal Period Focus FY    
Amendment Flag false    
v3.25.0.1
Audit Information
12 Months Ended
Dec. 29, 2024
Audit Information [Abstract]  
Auditor Firm ID 42
Auditor Name Ernst & Young LLP
Auditor Location San Diego, California
v3.25.0.1
CONSOLIDATED BALANCE SHEETS - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Current assets:    
Cash and cash equivalents $ 1,127 $ 1,048
Short-term investments 93 6
Accounts receivable, net 735 734
Inventory, net 547 587
Prepaid expenses and other current assets 244 234
Total current assets 2,746 2,609
Property and equipment, net 815 1,007
Operating Lease, Right-of-Use Asset 419 544
Goodwill 1,113 2,545
Intangible assets, net 295 2,993
Deferred tax assets, net 567 56
Other assets 348 357
Total assets 6,303 10,111
Current liabilities:    
Accounts payable 221 245
Accrued liabilities 827 1,325
Term debt, current portion 499 0
Total current liabilities 1,547 1,570
Operating lease liabilities 554 687
Term debt 1,490 1,489
Other long-term liabilities 339 620
Commitments and contingencies
Stockholders’ equity:    
Preferred stock, $0.01 par value, 10 million shares authorized; no shares issued and outstanding at December 29, 2024 and December 31, 2023 0 0
Common stock, $0.01 par value, 320 million shares authorized; 200 million shares issued and 159 million outstanding at December 29, 2024; 199 million shares issued and 159 million outstanding at December 31, 2023 2 2
Additional paid-in capital 7,525 9,555
Accumulated other comprehensive income (loss) 22 (1)
Accumulated deficit (1,242) (19)
Treasury stock, at cost; 41 million shares and 40 million shares at December 29, 2024 and December 31, 2023, respectively (3,934) (3,792)
Total stockholders’ equity 2,373 5,745
Total liabilities and stockholders’ equity $ 6,303 $ 10,111
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CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares
Dec. 29, 2024
Dec. 31, 2023
Statement of Financial Position [Abstract]    
Preferred stock, par value (in dollars per share) $ 0.01 $ 0.01
Preferred stock, shares authorized (in shares) 10,000,000 10,000,000
Preferred stock, shares issued (in shares) 0 0
Preferred stock, shares outstanding (in shares) 0 0
Common stock, par value (in dollars per share) $ 0.01 $ 0.01
Common stock, shares authorized (in shares) 320,000,000 320,000,000
Common stock, shares issued (in shares) 200,000,000 199,000,000
Common stock, shares outstanding (in shares) 159,000,000 159,000,000
Treasury stock, common shares (in shares) 41,000,000 40,000,000
v3.25.0.1
CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Revenue:      
Total revenue $ 4,372 $ 4,504 $ 4,584
Cost of revenue:      
Amortization of acquired intangible assets 127 191 173
Total cost of revenue 1,511 1,760 1,612
Gross profit 2,861 2,744 2,972
Operating expense:      
Research and development 1,169 1,354 1,321
Selling, general and administrative 1,092 1,612 1,297
Goodwill and intangible impairment 1,889 827 3,914
Legal contingency and settlement (456) 20 619
Total operating expense 3,694 3,813 7,151
Loss from operations (833) (1,069) (4,179)
Other income (expense):      
Interest income 46 58 11
Interest expense (100) (77) (26)
Other expense, net (292) (29) (142)
Total other expense, net (346) (48) (157)
Total loss before income taxes (1,179) (1,117) (4,336)
Provision for income taxes 44 44 68
Net loss $ (1,223) $ (1,161) $ (4,404)
Loss per share:      
Basic (in dollars per share) $ (7.69) $ (7.34) $ (28.00)
Diluted (in dollars per share) $ (7.69) $ (7.34) $ (28.00)
Shares used in computing loss per share:      
Basic (in shares) 159,000,000 158,000,000 157,000,000
Diluted (in shares) 159,000,000 158,000,000 157,000,000
Product      
Revenue:      
Total revenue $ 3,656 $ 3,787 $ 3,953
Cost of revenue:      
Cost of revenue 1,017 1,177 1,144
Service      
Revenue:      
Total revenue 716 717 631
Cost of revenue:      
Cost of revenue $ 367 $ 392 $ 295
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CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Statement of Comprehensive Income [Abstract]      
Net loss $ (1,223) $ (1,161) $ (4,404)
Unrealized gain (loss) on cash flow hedges, net of deferred tax 23 (4) (14)
Total comprehensive loss $ (1,200) $ (1,165) $ (4,418)
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CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
shares in Thousands, $ in Millions
Total
Cumulative Effect, Period of Adoption, Adjustment
Common Stock
Additional Paid-In Capital
Additional Paid-In Capital
Cumulative Effect, Period of Adoption, Adjustment
Accumulated Other Comprehensive Income (Loss)
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit)
Cumulative Effect, Period of Adoption, Adjustment
Treasury Stock
Beginning balance (in shares) at Jan. 02, 2022     197,000            
Beginning balance at Jan. 02, 2022 $ 10,740 $ (32) $ 2 $ 8,938 $ (93) $ 17 $ 5,485 $ 61 $ (3,702)
Beginning balance (in shares) at Jan. 02, 2022                 (40,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (4,404)           (4,404)    
Unrealized loss on cash flow hedges, net of deferred tax (14)         (14)      
Issuance of common stock, net of repurchases (in shares)     1,000            
Issuance of common stock, net of repurchases 10     63         $ (53)
Share-based compensation 299     299          
Ending balance (in shares) at Jan. 01, 2023     198,000            
Ending balance at Jan. 01, 2023 $ 6,599   $ 2 9,207   3 1,142   $ (3,755)
Ending balance (in shares) at Jan. 01, 2023                 (40,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Accounting Standards Update [Extensible List] ASU 2020-06                
Net loss $ (1,161)           (1,161)    
Unrealized loss on cash flow hedges, net of deferred tax (4)         (4)      
Issuance of common stock, net of repurchases (in shares)     1,000            
Issuance of common stock, net of repurchases 27     64         $ (37)
Share-based compensation 275     275          
Reclassification of liability-classified awards $ 9     9          
Ending balance (in shares) at Dec. 31, 2023 159,000   199,000            
Ending balance at Dec. 31, 2023 $ 5,745   $ 2 9,555   (1) (19)   $ (3,792)
Ending balance (in shares) at Dec. 31, 2023 (40,000)               (40,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss $ (1,223)           (1,223)    
Unrealized loss on cash flow hedges, net of deferred tax 23         23      
Issuance of common stock, net of repurchases (in shares)     1,000           (1,000)
Issuance of common stock, net of repurchases (91)     51         $ (142)
Share-based compensation 318     318          
Spin-Off of GRAIL (see Note 2) $ (2,399)     (2,399)          
Ending balance (in shares) at Dec. 29, 2024 159,000   200,000            
Ending balance at Dec. 29, 2024 $ 2,373   $ 2 $ 7,525   $ 22 $ (1,242)   $ (3,934)
Ending balance (in shares) at Dec. 29, 2024 (41,000)               (41,000)
v3.25.0.1
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Cash flows from operating activities:        
Net loss $ (1,223) $ (1,161) $ (4,404)  
Adjustments to reconcile net loss to net cash provided by operating activities:        
Depreciation expense 224 235 215  
Amortization of intangible assets 130 197 179  
Share-based compensation expense 370 380 366  
Deferred income taxes (112) (33) (23)  
Net losses on strategic investments 312 40 122  
Change in fair value of contingent consideration liabilities (315) (24) (205)  
(Gain) loss on Helix contingent value right (15) (10) 7  
Goodwill and intangible (IPR&D) impairment 1,889 827 3,914  
Property and equipment and right-of-use asset impairment 46 100 9  
Other 14 17 8  
Changes in operating assets and liabilities:        
Accounts receivable (25) (40) (12)  
Inventory 19 (20) (135)  
Prepaid expenses and other current assets (14) 11 16  
Operating lease right-of-use assets and liabilities, net (32) (16) (8)  
Other assets (15) 5 19  
Accounts payable (4) (44) (38)  
Accrued liabilities (440) 15 381  
Other long-term liabilities 28 (1) (19)  
Net cash provided by operating activities 837 478 392  
Cash flows from investing activities:        
Net purchases of property and equipment (128) (195) (286)  
Net purchases of strategic investments (52) (6) (40)  
Cash paid for acquisitions and intangible assets, net of cash acquired (81) (30) (265)  
Cash received for Helix contingent value right 83 0 0  
Net cash used in investing activities (178) (231) (591)  
Cash flows from financing activities:        
Proceeds from debt, net of issuance costs   (1)    
Proceeds from debt, net of issuance costs 1,241   991  
Payments on debt obligations (750) (1,235) 0  
Payments on contingent consideration liabilities (1) (1) 0  
Proceeds from issuance of common stock 56 67 63  
Taxes paid related to net share settlement of equity awards (32) (40) (54)  
Common stock repurchases (116)   0 $ 0
GRAIL cash deconsolidated as a result of spin-off (968) 0 0  
Net cash (used in) provided by financing activities (570) (1,210) 1,000  
Effect of exchange rate changes on cash and cash equivalents (10) 0 (22)  
Net increase (decrease) in cash and cash equivalents 79 (963) 779  
Cash and cash equivalents 1,127 1,048 2,011 $ 1,232
Supplemental cash flow information:        
Cash paid for interest 83 73 17  
Cash paid for income taxes 105 65 122  
Cash paid for operating lease liabilities 132 123 112  
Purchases of property and equipment included in accounts payable and accrued liabilities 4 12 16  
GRAIL net assets, excluding cash and cash equivalents, deconsolidated as a result of spin-off $ 1,770 $ 0 $ 0  
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ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES
12 Months Ended
Dec. 29, 2024
Accounting Policies [Abstract]  
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES
1. ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES
Business Overview
We are a provider of sequencing- and array-based solutions, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. Our customers include leading genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies.
On June 24, 2024, we completed the separation (the Spin-Off) of GRAIL into a new public company through the distribution of 26,547,021 shares of GRAIL common stock to Illumina stockholders on a pro rata basis. The distribution reflected approximately 85.5% of the outstanding common stock of GRAIL as of 5:00 p.m. New York time on June 13, 2024, the record date for the distribution (the Record Date). We retained approximately 14.5% of the shares of GRAIL common stock immediately following the Spin-Off. The disposition of GRAIL did not meet the criteria to be reported as a discontinued operation and accordingly, GRAIL’s assets, liabilities, results of operations and cash flows have not been reclassified. Refer to note 2. GRAIL Spin-Off for additional details.
Basis of Presentation
The consolidated financial statements have been prepared in conformity with U.S. generally accepted accounting principles (GAAP) and include our accounts, our wholly-owned subsidiaries, and majority-owned or controlled companies. All intercompany transactions and balances have been eliminated in consolidation. Certain prior period amounts have been reclassified to conform to the current period presentation.
Variable Interest Entities (VIEs)
We evaluate our ownership, contractual and other interests in entities that are not wholly-owned to determine if these entities are VIEs, and, if so, whether we are the primary beneficiary of the VIE. In determining whether we are the primary beneficiary of a VIE and therefore required to consolidate the VIE, we apply a qualitative approach that determines whether we have both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. We continuously perform this assessment, as changes to existing relationships or future transactions may result in the consolidation or deconsolidation of a VIE. As of December 29, 2024, there were no VIEs for which we were the primary beneficiary and for which we were required to consolidate.
Use of Estimates
The preparation of the consolidated financial statements requires that management make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses, and related disclosures of contingent assets and liabilities. Though macroeconomic factors such as inflation, exchange rate fluctuations and concerns about an economic downturn present additional uncertainty, we continue to use the best information available to inform our critical accounting estimates. Actual results could differ from those estimates.
Fiscal Year
Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. References to 2024, 2023, and 2022 refer to fiscal years ended December 29, 2024, December 31, 2023, and January 1, 2023, respectively, which were all 52 weeks.
Functional Currency
The U.S. dollar is the functional currency of our international operations. We re-measure foreign subsidiaries’ monetary assets and liabilities to the U.S. dollar and record the net gains or losses resulting from re-measurement in other expense, net in the consolidated statements of operations.
Concentrations of Risk
Customers
We operate in markets that are highly competitive and rapidly changing. Significant technological changes, shifting customer needs, the emergence of competitive products or services with new capabilities, and other factors could negatively impact our operating results. A portion of our customers consist of university and research institutions that management believes are, to some degree, directly or indirectly supported by the United States Government. A significant change in current research funding, particularly with respect to funding of the U.S. National Institutes of Health or targeted cancellations by the U.S. federal government of certain grants or contracts, could have an adverse impact on future revenues and results of operations.
International sales entail a variety of risks, including currency exchange fluctuations, longer payment cycles, and greater difficulty in accounts receivable collection. We are also subject to general geopolitical risks, such as political, social and economic instability, and changes in diplomatic and trade relations. The risks of international sales are mitigated in part by the extent to which sales are geographically distributed. Shipments to customers outside the United States comprised 48%, 48%, and 50% of total consolidated revenue in 2024, 2023, and 2022, respectively. Customers outside the United States represented 53% and 55% of our gross trade accounts receivable balance as of December 29, 2024 and December 31, 2023, respectively.
We had no customers that provided more than 10% of total consolidated revenue in 2024, 2023, and 2022. We perform regular reviews of customer activity and associated credit risks and do not require collateral or enter into netting arrangements. Historically, we have not experienced significant credit losses from accounts receivable.
Financial Instruments
We are also subject to risks related to our financial instruments, including cash and cash equivalents, investments, and accounts receivable. Most of our cash and cash equivalents as of December 29, 2024 were deposited with U.S. financial institutions, either domestically or with their foreign branches. Our investment policy restricts the amount of credit exposure to any one issuer to 5% of the portfolio or 5% of the total issue size outstanding at the time of purchase and to any one industry sector, as defined by Clearwater Analytics (Industry Sector Report), to 30% of the portfolio at the time of purchase. There is no limit to the percentage of the portfolio that may be maintained in debt securities, U.S. government-sponsored entities, U.S. Treasury securities, and money market funds. Historically, we have not experienced significant credit losses from financial instruments.
Suppliers
We require customized products and components that currently are available from a limited number of sources. We source certain key products and components included in our products from single vendors. Historically, we have not experienced significant issues sourcing materials to build our products.
Segments
We report segment information based on the management approach, which designates the internal reporting used by the Chief Operating Decision Maker (CODM) for making decisions and assessing performance as the source of our reportable segments. Our CODM allocates resources and assesses the performance of segments using information about their revenue and net income (loss). Our CODM does not evaluate our segments using asset information.
Accounting Pronouncements Adopted in 2024
In December 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280) - Improvements to Reportable Segment Disclosures. The new standard requires a company to disclose incremental segment information on an annual and interim basis, including significant segment expenses and measures of profit or loss that are regularly provided to the CODM. The standard does not change how an entity identifies its operating segments. The standard was effective for us beginning in fiscal year 2024 and interim periods within fiscal year 2025. We adopted the standard on its effective date in fiscal year 2024 and applied the amendments retrospectively to all prior periods presented in the consolidated financial statements. See note 12. Segment and Geographic Information for additional details.
Accounting Pronouncements Adopted in 2022
In August 2020, the FASB issued ASU 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity’s Own Equity (Subtopic 815-40). The new standard reduces the number of accounting models for convertible debt instruments, amends the accounting for certain contracts in an entity’s own equity, and modifies how certain convertible instruments and contracts that may be settled in cash or shares impact the calculation of diluted earnings per share. Specifically, the guidance removes certain accounting models that separate the embedded conversion features from the host contract for convertible instruments and requires the use of the if-converted method to calculate diluted earnings per share. We adopted the standard on its effective date in the first quarter of 2022 using a modified retrospective approach by recognizing a cumulative-effect adjustment to retained earnings on January 3, 2022. As a result of the adoption of ASU 2020-06, we increased retained earnings and decreased additional paid-in capital by $61 million and $93 million, respectively.
Accounting Pronouncements Pending Adoption
In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses - Income Statement - Reporting Comprehensive Income - Expense Disaggregation Disclosures (Subtopic 220-40). The new standard requires a company to provide disaggregated disclosures, in the notes to the financial statements, of specified categories of expenses that are included in line items on the face of the income statement. The standard is effective for us beginning in fiscal year 2027 and interim periods within fiscal year 2028, with early adoption permitted. The new standard is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2024-03 on the consolidated financial statements and related disclosures.
In December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740) - Improvements to Income Tax Disclosures. The new standard requires a company to expand its existing income tax disclosures, specifically related to the rate reconciliation and income taxes paid. The standard is effective for us beginning in fiscal year 2025, with early adoption permitted, and is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2023-09 on the consolidated financial statements and related disclosures.
Revenue Recognition
Our revenue is generated from the sale of products and services. Product revenue consists of sales of instruments and consumables used in genetic analysis. Service and other revenue consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and, prior to the Spin-Off of GRAIL on June 24, 2024, cancer detection testing services related to the GRAIL business.
We recognize revenue when control of our products and services is transferred to our customers in an amount that reflects the consideration we expect to receive from our customers in exchange for those products and services. This process involves identifying the contract with a customer, determining the performance obligations in the contract, determining the contract price, allocating the contract price to the distinct performance obligations in the contract, and recognizing revenue when the performance obligations have been satisfied. Revenue recognition for contracts with multiple deliverables is based on the separate satisfaction of each distinct performance obligation within the contract. A performance obligation is considered distinct from other obligations in a contract when it provides a benefit to the customer either on its own or together with other resources that are readily available to the customer and is separately identified in the contract. We consider a performance obligation satisfied once we have transferred control of a good or service to the customer, meaning the customer has the ability to use and obtain the benefit of the good or service. The contract price is allocated to each performance obligation in proportion to its standalone selling price. We determine our best estimate of standalone selling price using average selling prices over a rolling 12-month period coupled with an assessment of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, we rely upon prices set by management, adjusted for applicable discounts.
Revenue from product sales is recognized generally upon delivery to the end customer, which is when control of the product is deemed to be transferred. Invoicing typically occurs upon shipment and payment is typically due within 30 days from invoice. In instances where right of payment or transfer of title is contingent upon the customer’s acceptance of the product, revenue is deferred until all acceptance criteria have been met. Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer. Revenue from instrument service contracts is recognized as the services are rendered, typically evenly over the contract term. Revenue from development and licensing agreements generally includes upfront and periodic licensing fees, contract research and development services, or payments for development and regulatory milestones. Revenue for these agreements is recognized when each distinct performance obligation is satisfied.
Revenue is recorded net of discounts, distributor commissions, and sales taxes collected on behalf of governmental authorities. Employee sales commissions are recorded as selling, general and administrative expense when incurred as the amortization period for such costs, if capitalized, would have been one year or less.
In certain markets, products and services are sold to customers through distributors. In most sales through distributors, the product is delivered directly to customers by us. The terms of sales transactions through distributors are consistent with the terms of direct sales to customers.
Loss per Share
Basic loss per share is computed based on the weighted average number of common shares outstanding during the period. Diluted loss per share is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. In loss periods, basic and diluted loss per share are identical since the effect of potentially dilutive common shares is antidilutive and therefore excluded. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares. Potentially dilutive common shares issuable upon conversion of convertible senior notes are determined using the if-converted method.
The weighted average shares used to calculate basic and diluted loss per share were as follows:
 Years Ended
In millionsDecember 29,
2024
December 31,
2023
January 1,
2023
Weighted average shares used in calculating basic loss per share
159 158 157 
Weighted average shares used in calculating diluted loss per share
159 158 157 
Antidilutive shares:
Equity awards4 
Convertible senior notes 
Potentially dilutive shares excluded due to antidilutive effect
4 
Fair Value Measurements
The fair value of assets and liabilities are based on the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value maximize use of observable inputs and minimize use of unobservable inputs. We use a fair value hierarchy with three levels of inputs, of which the first two are considered observable and the last unobservable, to measure fair value:
Level 1 — Quoted prices in active markets for identical assets or liabilities.
Level 2 — Inputs, other than Level 1, that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.
The carrying amounts of financial instruments such as cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable, and accrued liabilities approximate the related fair values due to the short-term maturities of these instruments.
Cash Equivalents and Investments
Cash equivalents are comprised of short-term, highly-liquid investments with original maturities of 90 days or less.
We have strategic investments in privately-held companies (non-marketable equity securities) and publicly traded companies (marketable equity securities). Our marketable equity securities are measured at fair value. Our non-marketable equity securities without readily determinable market values are initially measured at cost and adjusted to fair value for observable transactions for identical or similar investments of the same issuer or impairment. Equity investments are classified as current, short-term investments, or noncurrent, recorded in other assets, based on the nature of the securities and their availability for use in current operations. Realized and unrealized gains and losses on our equity investments are recorded in other expense, net in the consolidated statements of operations. Our equity investments are assessed for impairment quarterly. Impairment losses, equal to the difference between the carrying value and the fair value of the investment, are recorded in other expense, net.
We use the equity method to account for investments through which we have the ability to exercise significant influence, but not control, over the investee. Such investments are recorded in other assets, and our share of net income or loss is recognized on a one quarter lag in other expense, net.
Accounts Receivable
Trade accounts receivable are recorded at the net invoice value and are not interest-bearing. Receivables are considered past due based on the contractual payment terms. We reserve a percentage of our trade receivable balance based on collection history and current economic trends that we expect will impact the level of credit losses over the life of our receivables. These reserves are re-evaluated on a regular basis and adjusted, as needed. Once a receivable is deemed to be uncollectible, such balance is charged against the reserve.
Inventory
Inventory is stated at the lower of cost or net realizable value, on a first-in, first-out basis. Inventory includes raw materials and finished goods that may be used in the research and development process, and such items are expensed as consumed or capitalized as property and equipment and depreciated. Inventory write-downs for slow-moving, excess, and obsolete inventories are estimated based on product life cycles, quality issues, historical experience, and usage forecasts.
Property and Equipment
Property and equipment are stated at cost, subject to review for impairment, and depreciated over the estimated useful lives of the assets, using the straight-line method. Depreciation of leasehold improvements is recorded over the shorter of the lease term or the estimated useful life of the related assets. Maintenance and repairs are expensed as incurred. When assets are sold, or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and any gain or loss is included in operating expense.
Costs incurred to develop internal-use software during the application development stage are recorded at cost as computer software. Costs incurred in the development of such internal-use software, including external direct costs of materials and services and applicable compensation costs of employees devoted to specific software application development, are capitalized. Costs incurred outside of the application development stage are expensed as incurred.
The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years
Leases
We have various non-cancellable operating lease agreements for office, lab, manufacturing, and distribution facilities. These leases have remaining lease terms of 1 year to 14 years, which represent the non-cancellable periods of the leases and include extension options that we determined are reasonably certain to be exercised. We exclude extension options that are not reasonably certain to be exercised from our lease terms, ranging from 2 years to 20 years. Our lease payments consist primarily of fixed rental payments for the right to use the underlying leased assets over the lease terms, as well as payments for common-area-maintenance and administrative services. We often receive customary incentives from our landlords, such as reimbursements for tenant improvements and rent abatement periods, which effectively reduce the total lease payments owed for these leases. Leases are classified as operating or financing at commencement. As of December 29, 2024, we do not have any financing leases.
Operating lease right-of-use assets and liabilities on our consolidated balance sheets represent the present value of our remaining lease payments over the remaining lease terms, less any impairments recorded for right-of-use assets. We do not allocate lease payments to non-lease components; therefore, fixed payments for common-area-maintenance and administrative services are included in our operating lease right-of-use assets and liabilities. We use our incremental borrowing rate to calculate the present value of our lease payments, as the implicit rates in our leases are not readily determinable. Operating lease costs consist primarily of the fixed lease payments included in our operating lease liabilities and are recorded on a straight-line basis over the lease terms. We sublease certain real estate to third parties and this sublease income is also recorded on a straight-line basis.
Business Combinations
Under the acquisition method of accounting, we allocate the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. These valuations require us to make estimates and assumptions, especially with respect to intangible assets. We record the excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, as goodwill. Costs that we incur to complete the business combination, such as legal and other professional fees, are expensed as they are incurred.
In connection with certain acquisitions, contingent consideration can be earned by the sellers upon completion of certain future performance milestones. In these cases, a liability is recorded on the acquisition date, as a component of accrued liabilities and/or other long-term liabilities, for an estimate of the acquisition-date fair value of the contingent consideration. These estimates require management judgment, including probabilities of achieving certain future milestones. Changes in the fair value of the contingent consideration subsequent to the acquisition date are recognized in selling, general and administrative expense in our consolidated statements of operations.
If the initial accounting for a business combination is incomplete by the end of a reporting period that falls within the measurement period (not to exceed a year from the date of acquisition), we report provisional amounts in our financial statements. During the measurement period, we adjust the provisional amounts recognized at the acquisition date to reflect new information obtained about facts and circumstances that existed as of the acquisition date that, if known, would have affected the measurement of the amounts recognized as of that date. We record these adjustments to the provisional amounts with a corresponding offset to goodwill. Any adjustments identified after the measurement period are recorded in the consolidated statements of operations.
Goodwill, Intangible Assets and Other Long-Lived Assets
Assets acquired, including intangible assets and capitalized in-process research and development (IPR&D), and liabilities assumed are measured at fair value as of the acquisition date. Goodwill, which has an indefinite useful life, represents the excess of cost over fair value of the net assets acquired. Intangible assets acquired in a business combination that are used for IPR&D activities are considered indefinite lived until the completion or abandonment of the associated research and development efforts. Upon reaching the end of the relevant research and development project (i.e., upon commercialization), the IPR&D asset is amortized over its estimated useful life. If the relevant research and development project is abandoned, the IPR&D asset is expensed in the period of abandonment.
Goodwill and IPR&D are not amortized; however, they are reviewed for impairment at least annually during the second quarter, or more frequently if an event occurs indicating the potential for impairment. Goodwill and IPR&D are considered to be impaired if the carrying value of the reporting unit or IPR&D asset exceeds its respective fair value.
We perform our goodwill impairment analysis at the reporting unit level, which aligns with our reporting structure and availability of discrete financial information. During the goodwill impairment review, we assess qualitative factors to determine whether it is more likely than not that the fair values of our reporting units are less than the carrying amounts, including goodwill. The qualitative factors include, but are not limited to, macroeconomic conditions, industry and market considerations, and our overall financial performance. If, after assessing the totality of these qualitative factors, we determine that it is not more likely than not that the fair values of our reporting units are less than the carrying amounts, then no additional assessment is deemed necessary. Otherwise, we proceed to compare the estimated fair values of the reporting units with the carrying values, including goodwill. If the carrying amount of a reporting unit exceeds its fair value, we record an impairment loss based on the difference. We may elect to bypass the qualitative assessment in a period and proceed to perform the quantitative goodwill impairment test.
The IPR&D impairment test is performed by comparing the fair value of the asset to its carrying amount. When testing indefinite-lived intangibles for impairment, we may assess qualitative factors to determine whether it is more likely than not that the asset is impaired. Alternatively, we may bypass this qualitative assessment and perform a quantitative impairment test. If the IPR&D asset is impaired, the carrying value of the IPR&D is written down to the revised fair value with the related impairment charge recognized in the period in which the impairment occurs.
Our identifiable intangible assets with a finite life are typically comprised of acquired developed technologies, licensed technologies, customer relationships, license agreements, and trade names. The cost of identifiable intangible assets with finite lives is generally amortized on a straight-line basis over the assets’ respective estimated useful lives.
We perform regular reviews to determine if any event has occurred that may indicate that intangible assets with finite useful lives and other long-lived assets are potentially impaired. If indicators of impairment exist, an impairment test is performed to assess the recoverability of the affected assets by determining whether the carrying amount of such assets exceeds the undiscounted expected future cash flows. If the affected assets are not recoverable, we estimate the fair value of the assets and record an impairment loss in an amount equal to the excess of the carrying value over the fair value. Factors that may indicate potential impairment include a significant decline in our stock price and market capitalization compared to the net book value, significant changes in the ability of a particular asset to generate positive cash flows for our strategic business objectives, and the pattern of utilization of a particular asset.
We review our operating lease right-of-use assets for impairment whenever events or changes in circumstances indicate the carrying value of the right-of-use asset may not be recoverable. The evaluation is performed at the lowest level for which identifiable cash flows are largely independent of the cash flows of other groups of assets and liabilities. We consider a triggering event to reassess a right-of-use asset’s asset group to have occurred if we exit a portion of or the full facility or enter into a sublease. Factors that may indicate potential impairment include a significant decrease in the market price of an underlying leased asset group. If we conclude the carrying value of affected assets will not be recovered, we estimate the fair value of the assets and record an impairment in an amount equal to the excess of the carrying value over the fair value.
Derivative Financial Instruments
We are exposed to foreign exchange rate risks in the normal course of business and use derivative financial instruments to partially offset this exposure. We do not use derivative financial instruments for speculative or trading purposes. Foreign exchange contracts are carried at fair value in other current assets, other assets, accrued liabilities, or other long-term liabilities, as appropriate, on the consolidated balance sheets. The cash flows associated with such foreign exchange contracts, or derivative financial instruments, are classified as cash flows from operating activities in the consolidated statements of cash flows, which is the same category as the hedged transaction.
We use foreign exchange forward contracts to manage foreign currency risks related to monetary assets and liabilities denominated in currencies other than the U.S. dollar. These derivative financial instruments have terms of one month or less and are not designated as hedging instruments. Changes in fair value of these derivatives are recognized in other expense, net, along with the re-measurement gain or loss on the foreign currency denominated assets or liabilities. As of December 29, 2024, we had foreign exchange forward contracts in place to hedge exposures in the euro, Japanese yen, Australian dollar, Canadian dollar, Singapore dollar, Chinese Yuan Renminbi, and British pound. As of December 29, 2024 and December 31, 2023, the total notional amounts of outstanding forward contracts in place for these foreign currency purchases were $477 million and $926 million, respectively. In September 2024, as a result of the European Commission withdrawing its previously imposed fine, the related forward contracts we previously entered into for a total notional amount of €432 million were terminated.
We use foreign currency forward contracts to hedge portions of our foreign currency exposure associated with forecasted revenue transactions. These derivative financial instruments have terms up to 24 months and are designated as cash flow hedges. Changes in fair value are recorded as a component of accumulated other comprehensive income (loss) and are reclassified to revenue in the same period the underlying hedged transactions are recorded. We regularly review the effectiveness of our cash flow hedges and consider them to be ineffective if it becomes probable that the forecasted transactions will not occur in the identified period. Changes in fair value of the ineffective portions of our cash flow hedges, if any, are recognized in other expense, net. As of December 29, 2024, we had foreign currency forward contracts in place to hedge exposures associated with forecasted revenue transactions denominated in the euro, Japanese yen, Australian dollar, Canadian dollar, and Chinese Yuan Renminbi. As of December 29, 2024 and December 31, 2023, the total notional amounts of outstanding cash flow hedge contracts in place for these foreign currency purchases were $621 million and $628 million, respectively. We reclassified $15 million, $18 million, and $53 million to revenue in 2024, 2023, and 2022, respectively. As of December 29, 2024, the fair value of foreign currency forward contracts was $27 million, recorded in total assets. As of December 31, 2023, the fair value of foreign currency forward contracts recorded in total assets and total liabilities was $5 million and $9 million, respectively. Estimated gains reported in accumulated other comprehensive income (loss) expected to be reclassified into earnings within the next 12 months are $27 million as of December 29, 2024.
Warranties
We generally provide a one-year warranty on instruments. Additionally, we provide a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, an accrual is established for estimated warranty expenses based on historical experience as well as anticipated product performance. We periodically review the warranty reserve for adequacy and adjust the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.
Share-Based Compensation
Share-based compensation expense is incurred related to restricted stock, employee stock purchase plan (ESPP), stock options, and, prior to the GRAIL Spin-Off on June 24, 2024, cash-based equity incentive awards. Forfeitures are accounted for, as incurred, as a reversal of share-based compensation expense related to awards that will not vest.
Restricted stock units (RSU) and performance stock units (PSU) are both considered restricted stock. The determination of the amount of share-based compensation expense for our PSU requires the use of certain estimates and assumptions that affect the amount of share-based compensation expense recognized in our consolidated statements of operations. The fair value of restricted stock and performance stock units that do not include a market condition is determined by the closing market price of our common stock on the date of grant. PSU that do not include a market condition represent a right to receive a certain number of shares of common stock based on the achievement of corporate performance goals and continued employment during the vesting period. At each reporting period, we reassess the probability of the achievement of such corporate performance goals and any increase or decrease in share-based compensation expense resulting from an adjustment in the estimated shares to be released is treated as a cumulative catch-up in the period of adjustment. The fair value of performance stock units that include a market condition is determined on the date of grant using a Monte Carlo simulation, which includes assumptions for expected volatility, risk-free interest rate and dividend yield. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Share-based compensation expense is recognized based on the fair value on a straight-line basis over the requisite service periods of the awards. Compensation expense for PSU that include a market condition is recognized over the requisite service period regardless of whether the market conditions are achieved.
The Black-Scholes-Merton option-pricing model is used to estimate the fair value of stock purchased under our ESPP and stock options granted. The model assumptions include expected volatility, term, dividends, and the risk-free interest rate. The expected volatility is generally determined by weighing the historical and implied volatility of our common stock. The historical volatility is generally commensurate with the estimated expected term. The implied volatility is calculated from the implied market volatility of exchange-traded call options on our common stock. The expected term is generally based on historical forfeiture experience, exercise activity, and on the terms and conditions of the stock awards. The expected dividend yield is determined to be 0% given that we have never declared or paid cash dividends on our common stock and do not anticipate paying such cash dividends. The risk-free interest rate is based upon U.S. Treasury securities with remaining terms similar to the expected term of the share-based awards.
Cash-based equity incentive awards were classified as liability awards, as such awards were to be settled in cash. In connection with the Spin-Off of GRAIL, these awards were assumed by GRAIL. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, was used. The fair value of the awards was recorded over the respective vesting periods of the awards, with recognition of a corresponding liability recorded in accrued liabilities in the consolidated balance sheets. The awards were remeasured to fair value at each reporting date until the awards were settled, with changes in fair value recognized in share-based compensation expense.
Shipping and Handling Expenses
Shipping and handling expenses are included in cost of product revenue.
Research and Development
Research and development expenses include personnel expenses, contractor fees, facilities-related costs, material costs, and license fees. Expenditures relating to research and development are expensed in the period incurred.
Advertising Costs
Advertising costs are expensed as incurred and were $37 million, $36 million, and $53 million in 2024, 2023, and 2022, respectively.
Restructuring
We measure and accrue liabilities associated with employee separation costs, which primarily consist of severance pay and other separation costs such as outplacement services and benefits, at fair value as of the date the plan is approved and when such costs are reasonably estimable. The fair value measurement of restructuring related liabilities requires certain assumptions and estimates to be made, such as the retention period of certain employees. It is our policy to use the best estimates based on facts and circumstances available at the time of measurement, review the assumptions and estimates periodically, and adjust the liabilities when necessary.
Income Taxes
The provision for income taxes is computed using the asset and liability method, under which deferred tax assets and liabilities are recognized for the expected future tax consequences of temporary differences between the financial reporting and tax bases of assets and liabilities, and for the expected future tax benefit to be derived from tax loss and credit carryforwards. Deferred tax assets and liabilities are determined using the enacted tax rates in effect for the years in which those tax assets are expected to be realized. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in the provision for income taxes in the period that includes the enactment date.
Deferred tax assets are regularly assessed to determine the likelihood they will be recovered from future taxable income. A valuation allowance is established when we believe it is more likely than not the future realization of all or some of a deferred tax asset will not be achieved. In evaluating the ability to recover deferred tax assets within the jurisdiction which they arise, we consider all available positive and negative evidence. Factors reviewed include the cumulative pre-tax book income for the past three years, scheduled reversals of deferred tax liabilities, history of earnings and reliable forecasting, projections of pre-tax book income over the foreseeable future, and the impact of any feasible and prudent tax planning strategies.
The impact of a tax position is recognized in the consolidated financial statements only if that position is more likely than not of being sustained upon examination by taxing authorities, based on the technical merits of the position. Any interest and penalties related to uncertain tax positions will be reflected in income tax expense.
v3.25.0.1
GRAIL SPIN-OFF
12 Months Ended
Dec. 29, 2024
Discontinued Operations and Disposal Groups [Abstract]  
GRAIL SPIN-OFF
2. GRAIL SPIN-OFF
On June 24, 2024, we completed the Spin-Off of GRAIL into a separate, independent publicly traded company through the distribution of 26,547,021 shares of GRAIL common stock to Illumina stockholders on a pro rata basis. The GRAIL common stock distributed in the Spin-Off consisted of approximately 85.5% of the outstanding common stock of GRAIL as of the Record Date. The Spin-Off was structured as a tax-free spin-off and Illumina stockholders received one share of GRAIL common stock for every six shares of Illumina common stock held on the Record Date. We retained approximately 14.5% of the shares of GRAIL common stock immediately following the Spin-Off. The disposition of GRAIL did not meet the criteria to be reported as a discontinued operation and accordingly, GRAIL’s assets, liabilities, results of operations and cash flows have not been reclassified.
As part of the Spin-Off, we contributed to GRAIL an amount, in cash, to cover 2.5 years of GRAIL’s operations (the Disposal Funding), which was determined to be $974 million, less the cash and cash equivalents held by GRAIL.
The carrying amounts of GRAIL’s assets and liabilities included as part of the disposal group were as follows:
In millions
Cash and cash equivalents
$968 
Accounts receivable, net
13 
Inventory, net
22 
Prepaid expenses and other current assets
27 
Property and equipment, net
80 
Operating lease right-of-use assets
74 
Intangible assets, net(1)
2,201 
Other assets14 
Accounts payable(12)
Accrued liabilities (118)
Operating lease liabilities(62)
Other long term-liabilities(469)
GRAIL net assets
$2,738 
Amount of GRAIL net assets recorded to short-term investments
$397 
Amount of GRAIL net assets recorded to additional paid-in capital
$2,341 
Additional adjustments recorded to additional paid-in capital as a result of the GRAIL Spin-Off:
Non-contingent indemnification liability (see Note 7)
Tax adjustment for difference between the book and tax values of our retained investment in GRAIL
57 
Total recorded to additional paid-in capital as a result of the GRAIL Spin-Off
$2,399 
_____________
(1)Includes IPR&D with a carrying value of $140 million after impairment. Refer to note 5. Goodwill, Intangible Assets, and Acquisitions.
See note 12. Segment and Geographic Information for GRAIL’s results of operations, prior to the Spin-Off, included in our consolidated statements of operations for the periods presented within.
In planning for and executing the Spin-Off, we incurred $53 million and $17 million in separation-related transaction costs in 2024 and 2023, respectively, recognized in selling, general, and administrative expense. The costs primarily related to financial advisory, legal, regulatory and other professional services fees directly related to the Spin-Off.
In connection with the Spin-Off, Illumina and GRAIL entered into various agreements to effect the Spin-Off and provide a framework for GRAIL’s relationship with Illumina after the Spin-Off, including a separation and distribution agreement, an employee matters agreement, a tax matters agreement, an amended supply and commercialization agreement and a stockholder’s and registration rights agreement (the Agreements). The Agreements determine the treatment of the assets, employees, liabilities and obligations (including certain tax-related assets and liabilities) of Illumina attributable to periods prior to, at and after GRAIL’s separation and also govern certain relationships between Illumina and GRAIL after the Spin-Off.
v3.25.0.1
REVENUE
12 Months Ended
Dec. 29, 2024
Revenue from Contract with Customer [Abstract]  
REVENUE
3. REVENUE
Our revenue is generated from the sale of products and services. Product revenue consists of sales of instruments and consumables used in genetic analysis. Service and other revenue consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and prior to the Spin-Off of GRAIL on June 24, 2024, cancer detection testing services related to the GRAIL business.
Revenue by Source
202420232022
In millionsSequencingMicroarrayTotalSequencingMicroarrayTotalSequencingMicroarrayTotal
Consumables$2,858 $297 $3,155 $2,790 $293 $3,083 $2,919 $306 $3,225 
Instruments484 17 501 685 19 704 709 19 728 
Total product revenue3,342 314 3,656 3,475 312 3,787 3,628 325 3,953 
Service and other revenue651 65 716 637 80 717 543 88 631 
Total revenue$3,993 $379 $4,372 $4,112 $392 $4,504 $4,171 $413 $4,584 
Revenue by Geographic Area
Based on region of destination (in millions)20242023
2022(1)
Americas(2)
$2,441 $2,521 $2,479 
Europe1,185 1,140 1,089 
Greater China(3)
308 384 472 
Asia-Pacific, Middle East and Africa(4)
438 459 544 
Total revenue$4,372 $4,504 $4,584 
_____________
(1)We implemented a new global commercial structure in Q1 2023 to improve operating efficiencies and better align with local markets. We integrated Asia-Pacific and Japan with emerging markets across the Middle East, Africa, Turkey, and Commonwealth of Independent States (CIS). Beginning in Q1 2023, and going forward, we report regional results for the following regions: Americas, Europe, Greater China, and Asia-Pacific, Middle East and Africa (AMEA). Prior period amounts have been reclassified to conform to this new presentation.
(2)Americas revenue included United States revenue of $2,288 million, $2,359 million, and $2,290 million in 2024, 2023 and 2022, respectively.
(3)Region includes revenue from China, Taiwan, and Hong Kong.
(4)Region includes revenue from Russia and Turkey.
Performance Obligations
We regularly enter into contracts with multiple performance obligations. These contracts are believed to be firm as of the balance sheet date. However, we may allow customers to make product substitutions as we launch new products. The timing of shipments depends on several factors, including agreed upon shipping schedules, which may span multiple quarters. Most performance obligations are generally satisfied within a short time frame, approximately three to six months, after the contract execution date. As of December 29, 2024, the aggregate amount of the transaction price allocated to remaining performance obligations was $657 million, of which approximately 78% is expected to be converted to revenue in 2025, approximately 10% in the following twelve months, and the remainder thereafter.
Contract Assets and Liabilities
Contract assets, which consist of revenue recognized and performance obligations satisfied or partially satisfied in advance of customer billing, as of December 29, 2024 and December 31, 2023, were $16 million and $18 million, respectively, all of which were short-term and recorded in prepaid expenses and other current assets.
Contract liabilities, which consist of deferred revenue and customer deposits, as of December 29, 2024 and December 31, 2023, were $327 million and $329 million, respectively, of which the short-term portions of $260 million and $252 million, respectively, were recorded in accrued liabilities and the remaining long-term portions were recorded in other long-term liabilities. Revenue recorded in 2024 included $245 million of previously deferred revenue that was included in contract liabilities as of December 31, 2023.
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS
12 Months Ended
Dec. 29, 2024
Fair Value Disclosures [Abstract]  
INVESTMENTS AND FAIR VALUE MEASUREMENTS
4. INVESTMENTS AND FAIR VALUE MEASUREMENTS
Strategic Investments
Marketable Equity Securities
Our short-term investments consist of marketable equity securities. As of December 29, 2024 and December 31, 2023, the fair value of our marketable equity securities totaled $93 million and $6 million, respectively. The increase in our marketable equity securities relates to the investment we retained in GRAIL subsequent to the Spin-Off, which was initially recorded as $397 million, representing 14.5% of GRAIL’s net assets disposed of at Spin-Off. Refer to note 2. GRAIL Spin-Off for details. We recorded an unrealized loss of $309 million in 2024, subsequent to the Spin-Off, based on the fair value of our investment in GRAIL as of December 29, 2024.
Gains and (losses) recognized in other expense, net on marketable equity securities were as follows:
In millions202420232022
Net (losses) recognized during the period on marketable equity securities
$(310)$(2)$(81)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period
 (2)— 
Net unrealized (losses) recognized during the period on marketable equity securities still held at the reporting date
$(310)$— $(81)
Non-Marketable Equity Securities
As of December 29, 2024 and December 31, 2023, non-marketable equity securities, without readily determinable fair values, included in other assets, were $26 million and $28 million, respectively.
Venture Funds
We invest in three venture capital investment funds (the Funds), which are accounted for as equity-method investments. The aggregate carrying amount of the Funds, included in other assets, was $201 million and $168 million as of December 29, 2024 and December 31, 2023, respectively. We recorded a net gain of $5 million in 2024, and net losses of $33 million and $25 million in 2023 and 2022, respectively, in other expense, net.
Our commitments to the Funds are as follows:
Dollars in millions
Capital commitments
Callable through date
Remaining callable as of December 29, 2024(1)
Fund I
$100 April 2026$
Fund II
$150 July 2029$46 
Fund III
$60 December 2034$47 
_____________
(1)Fund I also had recallable distributions of approximately $10 million.
Revenue recognized from transactions with our strategic investees was $20 million, $69 million, and $113 million in 2024, 2023, and 2022, respectively.
Fair Value Measurements
The following table presents the hierarchy for assets and liabilities measured at fair value on a recurring basis:
December 29, 2024December 31, 2023
In millionsLevel 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets:
Money market funds (cash equivalents)$931 $ $ $931 $774 $— $— $774 
Marketable equity securities93   93 — — 
Other investments
  17 17 — — — — 
Helix contingent value right    — — 68 68 
Deferred compensation plan assets 70  70 — 61 — 61 
Total assets measured at fair value$1,024 $70 $17 $1,111 $780 $61 $68 $909 
Liabilities:
Contingent consideration liabilities$ $ $73 $73 $— $— $387 $387 
Deferred compensation plan liability 65  65 — 59 — 59 
Total liabilities measured at fair value$ $65 $73 $138 $— $59 $387 $446 
Marketable equity securities are measured at fair value based on quoted trade prices in active markets. Other investments, included in other assets, consist of convertible notes, for which we elected the fair value option. Fair value is derived using a probability-weighted scenario approach. Changes in fair value are recognized in other expense, net. Deferred compensation plan assets consist primarily of investments in life insurance contracts carried at cash surrender value, which reflects the net asset value of the underlying publicly traded mutual funds. We corroborate the fair value of our holdings, comparing valuations obtained from our investment service provider to valuations reported by our asset custodians, validating pricing sources and models, and reviewing key model inputs.
Helix Contingent Value Right
In conjunction with the deconsolidation of Helix Holdings I, LLC (Helix) in April 2019, we received a contingent value right with a 7-year term that entitled us to consideration dependent upon the outcome of Helix’s future financing and/or liquidity events. We elected the fair value option to measure the contingent value right received from Helix. Changes in the estimated fair value are recognized in other expense, net. We estimated the fair value of the contingent value right using a Monte Carlo simulation. Estimates and assumptions used in the Monte Carlo simulation included probabilities related to the timing and outcome of future financing and/or liquidity events, assumptions regarding collectability and volatility, and an estimated equity value of Helix. These unobservable inputs represented a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. On July 31, 2024, we received cash of $83 million to settle the contingent value right early.
Changes in the Helix contingent value right were as follows:
In millions
Balance as of January 2, 2022$65 
Change in estimated fair value(7)
Balance as of January 1, 202358 
Change in estimated fair value10 
Balance as of December 31, 202368 
Change in estimated fair value15 
Cash received to settle(83)
Balance as of December 29, 2024$ 
Contingent Consideration Liabilities
We reassess the fair value of contingent consideration related to acquisitions on a quarterly basis, with changes in the fair value, subsequent to the acquisition date, recognized in selling, general and administrative expense. The contingent value rights issued as part of the GRAIL acquisition entitle the holders to receive future cash payments on a quarterly basis (Covered Revenue Payments) representing a pro rata portion of certain GRAIL-related revenues (Covered Revenues) each year for a 12-year period (through August 2033). As defined in the Contingent Value Rights Agreement, this will reflect a 2.5% payment right to the first $1 billion of revenue each year for 12 years. Revenue above $1 billion each year will be subject to a 9% contingent payment right during this same period. Covered Revenues for the periods Q4 2023 through Q3 2024, Q4 2022 through Q3 2023, and Q4 2021 through Q3 2022 were $117 million, $85 million, and $42 million, respectively, driven primarily by sales of GRAIL’s Galleri test. Covered Revenue Payments relating to such periods were $1.1 million, $803,000, and $396,000 in 2024, 2023, and 2022, respectively. A portion of the Covered Revenue Payments in 2022 were applied to reimburse us for certain expenses.
The fair value of our contingent consideration liability related to GRAIL was $71 million and $387 million as of December 29, 2024 and December 31, 2023, respectively, of which $70 million and $385 million, respectively, was included in other long-term liabilities, with the remaining balances included in accrued liabilities. We use a Monte Carlo simulation to estimate the fair value of the GRAIL contingent consideration liability. Estimates and assumptions used in the Monte Carlo simulation include forecasted revenues for GRAIL, a revenue risk premium, a revenue volatility estimate, an operational leverage ratio and a counterparty credit spread. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Subsequent to the Spin-Off, we no longer have access to GRAIL management’s forecasts. Therefore, we must rely on information made public by GRAIL’s management and, beginning in Q4 2024, information published in analyst reports to estimate forecasted revenues through August 2033. In August 2024, GRAIL publicly announced a corporate restructure, including a reduction in headcount and planned hires and a substantial decrease in certain R&D projects and investments. To estimate the liability as of December 29, 2024, we selected a revenue risk premium of 9%, which was derived from reconciling our forecasted revenues for GRAIL to GRAIL’s market capitalization based on a 60-day trailing average. The significant decrease in the contingent consideration liability from December 31, 2023 was due to a decrease in the forecasted revenues, following revised revenue projections announced by GRAIL in May 2024 and the restructuring announcement in August 2024.
The assumptions used in estimating the fair value of the contingent consideration liability related to GRAIL are inherently subject to uncertainty and we note that small changes in these assumptions could have a significant impact on the concluded value. For example, an increase or decrease of 20%, in each year, to the forecasted revenues would have resulted in an increase of $17 million and a decrease of $18 million, respectively, in the liability as of December 29, 2024. Additionally, an increase or decrease of 250 basis points to the selected revenue risk premium would have resulted in a decrease of $12 million and an increase of $15 million, respectively. We expect certain levels of volatility in the GRAIL contingent consideration liability are possible in future periods.
Changes in the estimated fair value of our contingent consideration liabilities were as follows:
In millions
Balance as of January 2, 2022$615 
Acquisition
Change in estimated fair value(205)
Balance as of January 1, 2023412 
Change in estimated fair value(24)
Cash payments(1)
Balance as of December 31, 2023387 
Acquisition2 
Change in estimated fair value(315)
Cash payments(1)
Balance as of December 29, 2024$73 
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS
12 Months Ended
Dec. 29, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS
5. GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS
Goodwill
In millions
Balance as of January 1, 2023(1)
$3,239 
Impairment(712)
Acquisition18 
Balance as of December 31, 20232,545 
Impairment(1,466)
Acquisition34 
Balance as of December 29, 2024$1,113 
_____________
(1) The balance as of January 1, 2023 includes accumulated impairment of $3,914 million related to our GRAIL reporting unit.
2024 Impairment of Goodwill
Goodwill is reviewed for impairment annually, during the second quarter of our fiscal year, or more frequently if an event occurs indicating the potential for impairment. In May 2024, we performed our annual goodwill impairment test for our two reporting units: Core Illumina and GRAIL. We performed a quantitative test for both reporting units. GRAIL’s carrying value exceeded its fair value, estimated as $580 million, and we recorded a goodwill impairment of $1,466 million in Q2 2024. There was no impairment for Core Illumina, as its fair value exceeded its carrying value.
To determine the fair value of GRAIL as of May 2024, we utilized enterprise value estimates of GRAIL, as estimated by investment bankers for purposes of determining pricing for the Spin-Off. Estimates and assumptions used to derive the investment bankers’ enterprise value estimates included estimated revenues for a two year period based on assumed growth rates and implied revenue multiples for comparable companies. These estimates and assumptions represent a Level 3 measurement as they are supported by little or no market activity and reflect our own assumptions in measuring fair value. An increase in estimated enterprise values for GRAIL of 100% would still have resulted in a full impairment of goodwill. In prior periods, we used a combination of both an income (discounted cash flow) and market approach to determine the fair value of GRAIL. The income approach utilized estimated cash flows for GRAIL based on a long-range plan, for a 15 year period, which contemplated FDA approval. Based on this approach, in Q3 2023, we estimated the fair value of GRAIL to be $3.6 billion and using this same approach in Q4 2023 suggested no further decrement in fair value. Initial analyst coverage of GRAIL from December 2023 into the spring of 2024 suggested that GRAIL could be valued between $3 billion and $4 billion. By May 2024, prior to the consummation of the GRAIL Spin-Off, additional information about GRAIL had become available in GRAIL’s amended Form 10 filings and a publicly available management presentation, which included updated disclosure about GRAIL’s business and anticipated near term financial trends. Prior to the consummation of the GRAIL Spin-Off, the amount of GRAIL’s Disposal Funding, $974 million, was also disclosed. Analyst and banker valuation estimates then began to estimate fair values between $400 million and $770 million, consistent with the impairment recorded in Q2 2024.
To determine the fair value of Core Illumina, we used a combination of both an income and market approach consistent with prior periods. The income approach utilized estimated discounted cash flows for the reporting unit, while the market approach utilized comparable company information. Estimates and assumptions used in the income approach included projected cash flows and a discount rate and represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value.
We evaluated GRAIL’s IPR&D intangible asset for potential impairment, in May 2024, as part of our annual test. We also concluded that the when-issued trading activity for GRAIL’s common stock, in June 2024, represented a triggering event that required an additional impairment test be performed. The carrying value of the IPR&D asset exceeded its estimated fair value and we recorded an impairment of $420 million in Q2 2024. The fair value of GRAIL’s IPR&D was determined by the income approach, using a discounted cash flow model. Estimates and assumptions used in the income approach, which represent a Level 3 measurement, included projected cash flows and a discount rate of 46.5%. The discount rate was derived from reconciling GRAIL’s long-range plan, which contemplated FDA approval and estimated cash flows for a 15 year period, to observed market values of GRAIL based on when-issued trading activity. An increase of 300 basis points to the discount rate used in our analysis would have resulted in additional impairment of $20 million. There is substantial risk inherent in forecasting revenues and spend associated with research and development, including assumptions around the timing and level of resources and investment to be made, which were made more challenging in light of the Spin-Off and related Disposal Funding.
We performed a recoverability test for GRAIL’s definite-lived intangible assets, which included developed technology and trade name, noting no impairment. No impairment was noted for Core Illumina definite-lived intangible assets.
2023 Impairment of Goodwill
In Q3 2023, we concluded that the sustained decrease in the Company’s stock price and overall market capitalization during the quarter was a triggering event indicating the fair values of our reporting units might be less than their carrying amounts and that an interim impairment test was required. Based on our analysis, we concluded GRAIL’s carrying value exceeded its fair value and recorded a goodwill impairment of $712 million, primarily due to the decrease in the Company’s consolidated market capitalization and a higher discount rate selected for the fair value calculation of GRAIL. There was no impairment for Core Illumina, as its fair value exceeded its carrying value.
We performed our interim goodwill impairment test using a combination of both an income and a market approach to determine the fair value of each reporting unit. The income approach utilized the estimated discounted cash flows for each reporting unit, while the market approach utilized comparable company information. Estimates and assumptions used in the income approach included projected cash flows for both GRAIL and Core Illumina and a discount rate for each reporting unit. Discount rates were determined using a weighted average cost of capital for risk factors specific to each reporting unit and other market and industry data. For GRAIL, the selected discount rate was 24.0%. An increase of 50 to 100 basis points to the discount rate would have resulted in additional impairment of $200 million to $350 million. The estimates and assumptions used in our assessment represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. In order to further validate the reasonableness of the fair values concluded for our reporting units, a reconciliation to market capitalization was performed by estimating a reasonable implied control premium and other market factors.
In conjunction with our interim goodwill impairment test, we also evaluated GRAIL’s IPR&D intangible asset for potential impairment. We performed our impairment test by comparing the carrying value of the IPR&D intangible asset to its estimated fair value, which was determined by the income approach, using a discounted cash flow model. Estimates and assumptions used in the income approach, which represent a Level 3 measurement, included projected cash flows and a selected discount rate of 19.0%. Based on our analysis, the carrying value of GRAIL’s IPR&D intangible asset exceeded its estimated fair value and we recorded an impairment of $109 million in Q3 2023, primarily due to a decrease in projected cash flows and a higher discount rate selected for the fair value calculation of the IPR&D asset. We also performed a recoverability test for the definite-lived intangible assets assigned to GRAIL, which included developed technology and trade name, and to Core Illumina and noted no impairment.
In Q4 2023, we concluded, among other events, that our formal announcement to divest GRAIL represented a triggering event that required an additional interim impairment test be performed. As a result of our analysis, no impairment was recorded for Core Illumina or GRAIL. The fair value of GRAIL exceeded its carrying value by approximately $950 million and the selected discount rate used in the analysis was 23.0%. An increase of 100 basis points to the discount rate would still have resulted in no impairment for GRAIL. We also performed a recoverability test for the definite-lived intangible assets assigned to GRAIL and Core Illumina and noted no impairment.
2022 Impairment of Goodwill
On July 13, 2022, the EU General Court ruled that the European Commission had jurisdiction under the EU Merger Regulation to review our acquisition of GRAIL. Additionally, on September 6, 2022, the European Commission issued its decision prohibiting the acquisition. See note 9. Legal Proceedings. These decisions, along with a continued and significant decrease in the Company’s stock price and market capitalization, required us to perform an interim impairment test in Q3 2022. Based on our analysis, we concluded GRAIL’s carrying value exceeded its fair value and recorded a goodwill impairment of $3,914 million, primarily due to the negative impact of capital market conditions and a higher discount rate selected for the fair value calculation of GRAIL. There was no impairment for Core Illumina.
We performed our interim goodwill impairment test using a combination of both an income and a market approach to determine the fair value of each reporting unit. The income approach utilized the estimated discounted cash flows for each reporting unit, while the market approach utilized comparable company information. Estimates and assumptions used in the income approach included projected cash flows for both GRAIL and Core Illumina and a discount rate for each reporting unit. Discount rates were determined using a weighted average cost of capital for risk factors specific to each reporting unit and other market and industry data. For GRAIL, the discount rate selected was 22.0%. In order to further validate the reasonableness of the fair values concluded for our reporting units, a reconciliation to market capitalization was performed by estimating a reasonable implied control premium and other market factors.
In conjunction with our interim goodwill impairment test, we also evaluated GRAIL’s IPR&D intangible asset for potential impairment. We performed our impairment test by comparing the carrying value of the IPR&D intangible asset to its estimated fair value, which was determined by the income approach, using a discounted cash flow model. Estimates and assumptions used in the income approach included projected cash flows and a discount rate. Based on our analysis, the carrying value of the IPR&D intangible asset did not exceed its estimated fair value and no impairment was recorded. We also performed a recoverability test for the definite-lived intangible assets assigned to GRAIL, which included developed technology and trade name, and to Core Illumina and noted no impairment.
Intangible Assets
 December 29, 2024December 31, 2023
In millionsGross
Carrying
Amount
Accumulated
Amortization
Intangible Assets,
Net
Gross
Carrying
Amount
Accumulated
Amortization
ImpairmentIntangible Assets,
Net
Developed technologies$465 $(305)$160 $2,807 $(585)$— $2,222 
Licensed technologies234 (114)120 274 (133)— 141 
License agreements19 (13)6 14 (13)— 
Customer relationships16 (14)2 14 (13)— 
Database12 (5)7 12 (3)— 
Trade name2 (2) 43 (14)— 29 
Total finite-lived intangible assets, net748 (453)295 3,164 (761)— 2,403 
In-process research and development (IPR&D)   705 — (115)590 
Total intangible assets, net$748 $(453)$295 $3,869 $(761)$(115)$2,993 
The significant decrease in developed technologies, trade name, and IPR&D reflect the GRAIL intangible assets disposed of in connection with the Spin-Off. See note 2. GRAIL Spin-Off for details. Also, in Q1 2024, we placed into service (reflected in developed technologies), with a useful life of 10 years, the $35 million IPR&D intangible asset we acquired in 2021, net of impairments recognized in 2024 and 2023 of $3 million and $6 million, respectively.
As a result of the Fluent BioSciences acquisition in Q3 2024, we recorded a developed technology asset of $42 million, with a useful life of 7 years, and a customer relationship asset of $2 million, with a useful life of 11 years. We are still finalizing the allocation of the purchase price as it relates to the completion of certain tax returns. We expect to finalize the valuation as soon as practicable, but no later than one year after the acquisition. As a result of an acquisition in Q4 2023, we recorded a developed technology asset of $19 million, with a useful life of 10 years. We finalized the allocation of the purchase price in Q4 2024 with no material adjustments to provisional amounts.
The estimated future annual amortization of finite-lived intangible assets is shown in the following table. Actual amortization expense to be reported in future periods could differ from these estimates as a result of acquisitions, divestitures, and asset impairments, among other factors.
In millionsEstimated Annual Amortization
2025$69 
202657 
202755 
202852 
202923 
Thereafter39 
Total$295 
v3.25.0.1
DEBT AND OTHER COMMITMENTS
12 Months Ended
Dec. 29, 2024
Debt Disclosure [Abstract]  
DEBT AND OTHER COMMITMENTS
6. DEBT AND OTHER COMMITMENTS
Summary of Term Debt Obligations
In millionsDecember 29,
2024
December 31,
2023
Principal amount of 2025 Term Notes outstanding$500 $500 
Principal amount of 2026 Term Notes outstanding500 — 
Principal amount of 2027 Term Notes outstanding500 500 
Principal amount of 2031 Term Notes outstanding500 500 
Unamortized discounts and debt issuance costs(11)(11)
Net carrying amount of term debt
1,989 1,489 
Less: current portion499 — 
Term debt, non-current
$1,490 $1,489 
Fair value of term debt outstanding (Level 2)
$1,940 $1,440 
Interest expense recognized on our term notes and delayed draw term loan, which included amortization of debt discounts and issuance costs, was $99 million, $74 million, and $21 million in 2024, 2023 and 2022, respectively.
4.650% Term Notes due 2026 (2026 Term Notes)
On September 9, 2024, we issued $500 million aggregate principal amount of 2026 Term Notes. After deducting discounts and issuance costs, we received net proceeds of $497 million, which were used to repay a portion of the outstanding debt under the Delayed Draw Credit Agreement. The 2026 Term Notes, which mature on September 9, 2026, accrue interest at a rate of 4.650% per annum, payable semi-annually on March 9 and September 9 of each year, beginning on March 9, 2025. We may redeem for cash all or any portion of the 2026 Term Notes, at our option, at any time prior to maturity at make-whole premium redemption prices as defined in the form of the notes.
5.800% Term Notes due 2025 (2025 Term Notes) and 5.750% Term Notes due 2027 (2027 Term Notes)
In December 2022, we issued $500 million aggregate principal amount of 2025 Term Notes and $500 million aggregate principal amount of 2027 Term Notes. After deducting discounts and issuance costs, we received net proceeds of $991 million. The 2025 Notes, which mature on December 12, 2025, and the 2027 Notes, which mature on December 13, 2027, accrue interest at a rate of 5.800% and 5.750% per annum, respectively, payable semi-annually. Interest for the 2025 Notes is payable on June 12 and December 12 of each year and interest for the 2027 Notes is payable on June 13 and December 13 of each year, beginning in June 2023.
We may redeem for cash all or any portion of the 2025 or 2027 Term Notes, at our option, at any time prior to maturity. Prior to November 12, 2025 for the 2025 Notes and prior to November 13, 2027 for the 2027 Notes, the notes are redeemable at make-whole premium redemption prices as defined in the applicable forms of note. After November 12, 2025 and November 13, 2027, respectively, the notes are redeemable at a redemption price equal to 100% of the principal to be redeemed, plus accrued and unpaid interest up to, but excluding, the redemption date.
0.550% Term Notes due 2023 (2023 Term Notes) and 2.550% Term Notes due 2031 (2031 Term Notes)
In March 2021, we issued $500 million aggregate principal amount of 2023 Term Notes and $500 million aggregate principal amount of 2031 Term Notes. After deducting discounts and issuance costs, we received net proceeds of $992 million. The 2023 Notes matured and were repaid in cash on March 23, 2023. The 2031 Notes, which mature on March 23, 2031, accrue interest at a rate of 2.550% per annum, payable semi-annually on March 23 and September 23 of each year. We may redeem for cash all or any portion of the 2031 Term Notes, at our option, at any time prior to maturity. Prior to December 23, 2030, the notes are redeemable at make-whole premium redemption prices as defined in the form of the notes. After December 23, 2030, the notes are redeemable at a redemption price equal to 100% of the principal to be redeemed, plus accrued and unpaid interest up to, but excluding, the redemption date.
Delayed Draw Term Loan due 2025
On June 17, 2024, we entered into a 364-day delayed draw credit agreement (the Delayed Draw Credit Agreement), which provided us with a senior unsecured term loan credit facility in an aggregate principal amount of up to $750 million (the Delayed Draw Credit Facility). On June 20, 2024, we borrowed $750 million on the credit facility in order to provide a portion of the Disposal Funding to GRAIL as part of the Spin-Off. The delayed draw term loan incurred interest at a rate of 6.7%. On September 9, 2024, we repaid the full principal outstanding on the Delayed Draw Credit Facility, as well as accrued interest, in an aggregate amount of $761 million and terminated the Delayed Draw Credit Agreement. We recognized a loss on debt extinguishment of $5 million in 2024, included in interest expense in the consolidated statements of operations, related to the write-off of unamortized debt issuance costs.
0% Convertible Senior Notes due 2023 (2023 Convertible Notes)
In August 2018, we issued $750 million aggregate principal amount of 2023 Convertible Notes. The notes were convertible into cash, shares of common stock or a combination of cash and shares of common stock, at our election, based on conversion rates as defined in the indenture. The 2023 Convertible Notes matured on August 15, 2023, at which time the principal was repaid in cash. We did not issue any shares of common stock.
The 2023 Convertible Notes were initially accounted for in accordance with authoritative guidance for convertible debt instruments that may be settled in cash upon conversion. The guidance required the carrying amount of the liability component to be estimated by estimating the fair value of a similar liability that does not have an associated conversion feature. Because at issuance we had no outstanding non-convertible public debt, we determined that market-traded senior, unsecured corporate bonds represented a similar liability without a conversion option. Based on market data available for publicly traded, senior, unsecured corporate bonds issued by companies in our industry, and with similar maturities to the 2023 Convertible Notes, we estimated an implied interest rate of 3.7%, assuming no conversion option. The estimated implied interest rate was applied to the 2023 Convertible Notes, which resulted in a fair value of the liability component in aggregate of $624 million upon issuance, calculated as the present value of implied future payments based on the $750 million aggregate principal amount. The $126 million difference ($93 million, net of tax) between the aggregate principal amount of $750 million and the estimated fair value of the liability component was recorded in additional paid-in capital as the 2023 Convertible Notes were not considered redeemable. As of January 3, 2022, we adopted ASU 2020-06, which removed the requirement to separate the embedded conversion feature from the notes and requires the notes to be accounted for as a single liability measured at amortized cost. Accordingly, we reclassified the unamortized debt discount from additional paid-in capital to convertible senior notes in the consolidated balance sheets on January 3, 2022. This resulted in an increase to retained earnings and a decrease to additional paid-in capital of $61 million and $93 million, respectively.
Interest expense recognized on our 2023 Convertible Notes was immaterial in both 2023 and 2022.
Revolving Credit Agreement
On January 4, 2023, we entered into a new credit agreement (the Revolving Credit Agreement), which provides us with a $750 million senior unsecured five-year revolving credit facility, including a $40 million sublimit for swingline borrowings and a $50 million sublimit for letters of credit (the Revolving Credit Facility). Proceeds of the loans under the Revolving Credit Facility may be used to finance working capital needs and for general corporate purposes. The credit agreement dated as of March 8, 2021 and the commitments thereunder were terminated as of January 4, 2023.
The Revolving Credit Facility matures, and all amounts outstanding become due and payable in full, on January 4, 2028, subject to two one-year extensions at our option, the consent of the extending lenders and certain other conditions. We may prepay amounts borrowed and terminate commitments under the Revolving Credit Facility at any time without premium or penalty. As of December 29, 2024, there were no borrowings or letters of credit outstanding under the credit facility, and we were in compliance with all financial and operating covenants.
Loans under the Revolving Credit Facility will have a variable interest rate based on either the term secured overnight financing rate (SOFR) or the alternate base rate, plus an applicable rate that varies with our debt rating and, in the case of loans bearing interest based on term SOFR, a credit spread adjustment equal to 0.10% per annum. The Revolving Credit Agreement includes an option for us to elect to increase commitments under the credit facility or enter into one or more tranches of term loans in the aggregate principal amount of up to $250 million, subject to consent of the lenders providing the additional commitments or loans and certain other conditions.
The Revolving Credit Agreement contains financial and operating covenants. Pursuant to the Revolving Credit Agreement, we are required to maintain a ratio of total debt to adjusted annual earnings before interest, taxes, depreciation and amortization (EBITDA), calculated based on the four consecutive fiscal quarters ending with the most recent fiscal quarter, of not greater than 3.50 to 1.00 as of the end of each fiscal quarter. Upon the consummation of any Qualified Acquisition (as defined in the Revolving Credit Agreement) and us providing notice to the Administrative Agent, the ratio increases to 4.00 to 1.00 for the fiscal quarter in which the acquisition is consummated and the three consecutive fiscal quarters thereafter. The operating covenants include, among other things, limitations on (i) the incurrence of indebtedness by our subsidiaries, (ii) liens on our and our subsidiaries assets, and (iii) certain fundamental changes and the disposition of assets by us and our subsidiaries. The Credit Agreement contains other customary covenants, representations and warranties, and events of default.
Leases
As of December 29, 2024, the maturities of our operating lease liabilities were as follows:
In millions
2025$105
2026105
2027103
202884
202981
Thereafter275
Total remaining lease payments
753
Less: imputed interest(120)
Total operating lease liabilities633
Less: current portion(79)
Long-term operating lease liabilities$554
Weighted-average remaining lease term8.0 years
Weighted-average discount rate4.4 %
The components of our lease costs were as follows:
In millions202420232022
Operating lease costs
$93 $116 $112 
Sublease income(19)(20)(20)
Variable lease costs(1)
25 27 20 
Total lease costs$99 $123 $112 
_____________
(1)Variable lease costs include non-fixed maintenance charges and property taxes.
Purchase Obligations
In the normal course of business, we enter into agreements to purchase goods or services that are not cancelable without penalty, primarily related to licensing and supply arrangements. For those agreements with variable terms, we do not estimate the total obligation beyond any minimum quantities or pricing as of the reporting date. Licensing agreements under which we commit to minimum royalty payments, some of which are subject to adjustment, may be terminated prior to the expiration of underlying intellectual property under certain circumstances. Annual minimum payments for noncancelable purchase obligations as of December 29, 2024 totaled $212 million, approximately half of which are due within the next twelve months.
v3.25.0.1
STOCKHOLDERS' EQUITY
12 Months Ended
Dec. 29, 2024
Equity [Abstract]  
STOCKHOLDERS' EQUITY
7. STOCKHOLDERS' EQUITY
The 2015 Stock and Incentive Compensation Plan (the 2015 Stock Plan) and the New Hire Stock and Incentive Plan allow for the issuance of stock options, performance stock options, restricted stock units and awards and performance stock units. In 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance by 8.0 million shares. In connection with the GRAIL Spin-Off, all unvested RSU and PSU were equitably adjusted pursuant to the plan to preserve their intrinsic value and the number of shares reserved for issuance under the 2015 Stock Plan was increased by 160,000 shares. As of December 29, 2024, approximately 5.4 million shares remained available for future grants under the 2015 Stock Plan. There is no set number of shares reserved for issuance under the New Hire Stock and Incentive Plan.
Restricted Stock
We issue restricted stock units (RSU) and performance stock units (PSU), both of which are considered restricted stock. We grant restricted stock pursuant to the 2015 Stock Plan and satisfy such grants through the issuance of either new shares or shares from treasury stock. RSU are share awards that, upon vesting, will deliver to the holder shares of our common stock. RSU generally vest over a four-year period with equal vesting annually. We issue three different PSU awards. We issue PSU for which the number of shares issuable at the end of a three-year performance period is based on our performance relative to specified earnings per share targets (EPS PSU) and, during 2024, we began to issue PSU for which the number of shares issuable at the end of a three-year performance period is based on our performance relative to specified operating margin targets (OM PSU). During 2023, we began to issue PSU with a market condition that vest based on the Company’s relative total shareholder return as compared to a peer group of companies measured over a three-fiscal year performance period (rTSR PSU). Depending on the actual performance over the measurement period, an rTSR PSU award recipient could receive up to 175% of the granted award. Shares issuable under all PSU awards are subject to continued employment through the vesting period.
Restricted stock activity was as follows:
Restricted
Stock Units
(RSU)
Performance
Stock Units
(PSU) (1)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987)— $268.08 $— 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
Awarded2,788 729 $133.73 $164.38 
Unvested adjustment for GRAIL Spin-Off
107 12 $ $ 
Vested(771) $249.70 $ 
Cancelled(443)(41)$195.11 $167.68 
Outstanding at December 29, 20243,879 700 $158.60 $164.87 
_____________
(1)For EPS and OM PSU, the number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. Awarded units are presented net of performance adjustments.
Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202420232022
Pre-tax intrinsic value of outstanding restricted stock:
RSU$525 $306 $326 
PSU$95 $— $15 
Fair value of restricted stock vested:
RSU$116 $122 $162 
PSU$ $— $49 
Liability-Classified RSU
In Q1 2023, we granted RSU that were to be settled in cash if stockholder approval to increase our share reserve under the amended and restated 2015 Stock Plan was not obtained. In Q2 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance. Upon such approval, all RSU previously accounted for as liability-classified awards, approximately 557,000 RSU, were reclassified to stockholders equity and accounted for prospectively as equity awards. There were no RSU liability-classified awards outstanding as of December 29, 2024 or December 31, 2023.
Stock Options
Stock option activity was as follows:
Units in thousandsOptionsWeighted-Average
Exercise Price
Performance Stock Options(1)
Weighted-Average
Exercise Price
Outstanding at January 2, 2022$66.42 17 $85.54 
Granted180 $330.25 — $— 
Exercised(1)$6.55 — $— 
Outstanding at January 1, 2023187 $319.72 17 $85.54 
Exercised(8)$71.09 (1)$16.69 
Cancelled(144)$330.25 — $— 
Outstanding at December 31, 202335 $330.25 16 $87.74 
Cancelled(35)$330.25 (16)$87.74 
Outstanding at December 29, 2024 $  $ 
_____________
(1)In connection with the GRAIL acquisition, we issued replacement performance stock options to GRAIL employees in 2021. The number of units reflected awards that had been granted and for which it was assumed to be probable that the underlying performance goals would be achieved. In connection with the GRAIL Spin-Off, all outstanding performance stock options were assumed by GRAIL.
The total intrinsic value of stock options exercised was immaterial in both 2023 and 2022. None exercised in 2024.
Other Liability-Classified Awards
Prior to the GRAIL Spin-Off, we granted cash-based equity incentive awards to GRAIL employees, which were accounted for as liability-classified awards. In connection with the Spin-Off, these awards were assumed by GRAIL. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, was used. The awards generally had terms of four years and vested in four equal installments on each anniversary of the grant date, subject to continued employment through the vesting period.
Cash-based equity incentive award activity was as follows:
In millions
Outstanding at January 2, 2022$184 
Granted168 
Vested and paid in cash
(41)
Cancelled(41)
Change in fair value23 
Outstanding at January 1, 2023293 
Granted116 
Vested and paid in cash
(77)
Cancelled(32)
Change in fair value(8)
Outstanding at December 31, 2023292 
Granted67 
Vested and paid in cash(54)
Cancelled(13)
Change in fair value(9)
Derecognition for GRAIL Spin-Off(1)
(283)
Outstanding at December 29, 2024$ 
_____________
(1)The estimated liability immediately prior to the Spin-Off, recorded in accrued liabilities, was $53 million, which was disposed of as part of GRAIL’s net assets. See note 2. GRAIL Spin-Off for additional details.
We recognized share-based compensation expense on these cash-based equity incentive awards of $52 million in 2024, prior to the Spin-Off, and $95 million and $67 million in 2023 and 2022, respectively.
In connection with the acquisition of GRAIL, we assumed a performance-based award for which vesting was based on GRAIL’s future revenues and had an aggregate potential value of up to $78 million. Prior to the Spin-Off of GRAIL, it was not probable that the performance conditions associated with the award would be achieved and, therefore, no share-based compensation expense was recognized in the consolidated statements of operations. In connection with the Spin-Off, this award was assumed by GRAIL. For a period of 2.5 years following the Spin-Off, we are obligated to indemnify GRAIL for cash payments that become earned and payable related to this award. The indemnification is accounted for in accordance with ASC 460. As of December 29, 2024, we recognized a non-contingent liability of $1 million for this indemnification, with a corresponding charge to additional paid-in capital.
Employee Stock Purchase Plan
The 2000 Employee Stock Purchase Plan, or ESPP, permits eligible employees to purchase common stock at a discount through payroll deductions during defined offering periods. The price at which stock is purchased under the ESPP is equal to 85% of the fair market value of the common stock on the first day of the offering period or purchase date, whichever is lower. The initial offering period commenced in July 2000. During 2024, 2023, and 2022, approximately 0.5 million, 0.4 million, and 0.3 million shares, respectively, were issued under the ESPP. As of December 29, 2024, approximately 12.4 million shares remained available for issuance under the ESPP, which includes an increase of 0.5 million shares pursuant to the terms of the ESPP to account for the GRAIL Spin-Off.
The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the ESPP were as follows:
202420232022
Risk-free interest rate
4.35% - 5.54%
 0.78% - 5.54%
0.06% - 2.98%
Expected volatility
41% - 49%
 41% - 51%
37% - 51%
Expected term
0.5 - 1.1 year
 0.5 - 1.1 year
0.5 - 1.0 year
Expected dividends0%0%0%
Weighted-average grant-date fair value per share$37.24 $49.87 $50.22 
Share Repurchases
In August 2024, our Board of Directors authorized a new share repurchase program, which cancels and supersedes all prior and available repurchase authorizations, to repurchase up to $1.5 billion of our outstanding common stock. The repurchases may be completed through open market purchases, pursuant to Rule 10b5-1 or Rule 10b-18, or through an accelerated share repurchase program. Authorizations to repurchase up to $1.4 billion of our outstanding common stock remained available as of December 29, 2024. We did not repurchase any shares during 2023 or 2022.
Share repurchase activity during 2024 was as follows:
In millions, except shares in thousands
Number of shares repurchased
904 
Total cost of shares repurchased(1)
$116 
_____________
(1)Total cost of shares repurchased includes the 1% excise tax imposed as part of the Inflation Reduction Act of 2022, which is calculated based on share repurchases, net of certain share issuances.
Subsequent to December 29, 2024 and through February 11, 2025, we repurchased an additional 1.0 million shares of our common stock for $126 million.
Share-Based Compensation
Share-based compensation expense, which includes expense for both equity and liability-classified awards, reported in our consolidated statements of operations was as follows:
In millions202420232022
Cost of product revenue$25 $29 $26 
Cost of service and other revenue6 
Research and development146 155 153 
Selling, general and administrative194 189 181 
Share-based compensation expense, before taxes371 380 366 
Related income tax benefits(83)(87)(83)
Share-based compensation expense, net of taxes$288 $293 $283 
As of December 29, 2024, unrecognized compensation cost, related to restricted stock and ESPP shares issued to date, of $565 million was expected to be recognized over a weighted-average period of approximately 2.5 years.
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS
12 Months Ended
Dec. 29, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
SUPPLEMENTAL BALANCE SHEET DETAILS
8. SUPPLEMENTAL BALANCE SHEET DETAILS
Accounts Receivable
In millionsDecember 29,
2024
December 31,
2023
Trade accounts receivable, gross$744 $741 
Allowance for credit losses(9)(7)
Total accounts receivable, net$735 $734 
Inventory
In millionsDecember 29,
2024
December 31,
2023
Raw materials$225 $276 
Work in process404 402 
Finished goods31 30 
Inventory, gross660 708 
Inventory reserve(113)(121)
Total inventory, net$547 $587 
Property and Equipment
In millionsDecember 29,
2024
December 31,
2023
Leasehold improvements$772 $803 
Machinery and equipment683 684 
Computer hardware and software478 463 
Furniture and fixtures53 55 
Buildings44 44 
Construction in progress39 96 
Total property and equipment, gross2,069 2,145 
Accumulated depreciation(1,254)(1,138)
Total property and equipment, net$815 $1,007 
Accrued Liabilities
In millionsDecember 29,
2024
December 31,
2023
Legal contingencies(1)
$26 $484 
Contract liabilities, current portion260 252 
Accrued compensation expenses
252 223 
Accrued taxes payable101 79 
Operating lease liabilities, current portion79 86 
Liability-classified equity incentive awards 55 
Other, including warranties(2)
109 146 
Total accrued liabilities$827 $1,325 
_____________
(1)See note 9. Legal Proceedings for additional details.
(2)See table below for changes in the reserve for product warranties.
Changes in the reserve for product warranties were as follows:
In millions
Balance as of January 2, 2022$22 
Additions charged to cost of product revenue23 
Repairs and replacements(27)
Balance as of January 1, 202318 
Additions charged to cost of product revenue42 
Repairs and replacements(39)
Balance as of December 31, 202321 
Additions charged to cost of product revenue42 
Repairs and replacements(45)
Balance as of December 29, 2024$18 
Restructuring
In Q2 2023, we implemented a cost reduction initiative that included workforce reductions, the consolidation of certain facilities and other actions to reduce expenses, all as part of a plan to realign operating expenses while maintaining focus on our innovation roadmap and sustainable long-term growth. In both 2024 and 2023, we recorded restructuring charges primarily consisting of asset impairments related to exit activities at certain of our leased facilities.
A summary of the pre-tax restructuring charges is as follows:
In millions20242023Cumulative charges recorded since inception
Employee separation costs$12 $48 $60 
Asset impairment charges(1)
46 100 146 
Other costs
Total restructuring charges(2)
$62 $152 $214 
_____________
(1)For 2024, relates to impairment of right-of-use assets and leasehold improvements for Foster City campus and other property in San Diego.
For 2023, primarily relates to impairment of right-of-use assets and leasehold improvements for our i3 and Foster City campuses.
(2)For 2024, $59 million was recorded in SG&A expense, $2 million in R&D expense, and remainder in cost of revenue.
For 2023, $122 million was recorded in SG&A expense, $24 million in R&D expense, and remainder in cost of revenue.
Total restructuring charges primarily relate to our Core Illumina segment.
In 2024, we recorded right-of-use asset impairments of $12 million and $19 million related to our campus in Foster City, California and another property in San Diego, California, respectively. In 2023, we recorded right-of-use asset impairments of $38 million and $21 million related to our i3 campus in San Diego and our campus in Foster City, respectively. The impairments were determined by comparing the fair values of the impacted right-of-use assets to the carrying values of the assets as of the impairment measurement date. The fair values of the right-of-use assets were estimated using the discounted future cash flows method, which includes estimates and assumptions for future sublease rental rates that reflect current sublease market conditions, as well as discount rates. The estimates and assumptions used in our assessments represent Level 3 measurements because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. In 2024, we recorded $14 million of leasehold improvement impairments related to our Foster City campus and, in 2023, we recorded $16 million and $22 million of leasehold improvement impairments related to our i3 and Foster City campuses, respectively. The right-of-use asset and leasehold improvement impairments were recognized in selling, general and administrative expense. We continue to evaluate our options for the rest of our Foster City campus, for which, as of December 29, 2024, we had remaining assets, consisting primarily of right-of-use assets and leasehold improvements, of $100 million.
A summary of the restructuring liability is as follows:
In millions
Employee Separation Costs
Other CostsTotal
Amount recorded in accrued liabilities as of January 1, 2023
$— $— $— 
Expense recorded
48 52 
Cash payments(31)(3)(34)
Amount recorded in accrued liabilities as of December 31, 2023
17 1 18 
Expense recorded
12 4 16 
Cash payments(24)(2)(26)
Adjustments to accrual(3)(1)(4)
Amount recorded in accrued liabilities as of December 29, 2024
$2 $2 $4 
v3.25.0.1
LEGAL PROCEEDINGS
12 Months Ended
Dec. 29, 2024
Commitments and Contingencies Disclosure [Abstract]  
LEGAL PROCEEDINGS
9. LEGAL PROCEEDINGS
We are involved in various lawsuits and claims arising in the ordinary course of business, including actions with respect to intellectual property, employment, and contractual matters. In connection with these matters, we assess, on a regular basis, the probability and range of possible loss based on the developments in these matters. A liability is recorded in the consolidated financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. Because litigation is inherently unpredictable and unfavorable resolutions could occur, assessing contingencies is highly subjective and requires judgments about future events. We regularly review outstanding legal matters to determine the adequacy of the liabilities accrued and related disclosures in consideration of many factors, which include, but are not limited to, past history, scientific and other evidence, and the specifics and status of each matter. We may change our estimates if our assessment of the various factors changes and the amount of ultimate loss may differ from our estimates, resulting in a material effect on our business, financial condition, results of operations, and/or cash flows.
Acquisition of GRAIL
As of September 6, 2024, all previously disclosed regulatory proceedings in the United States and European Union related to our acquisition of GRAIL have been resolved (as further described below).
On April 19, 2021, the European Commission sought and subsequently accepted a request for a referral of the GRAIL acquisition for European Union merger review, submitted by a Member State of the European Union (France), and joined by several other EEA Member States (Belgium, Greece, Iceland, the Netherlands and Norway), under Article 22(1) of Council Regulation (EC) No 139/2004 (the EU Merger Regulation). The European Commission had never solicited referrals to take jurisdiction over an acquisition of a U.S. company that had no revenue in Europe. On April 28, 2021, we filed an action in the General Court of the European Union (the EU General Court) asking for annulment of the European Commission’s assertion of jurisdiction to review the acquisition under Article 22 of the EU Merger Regulation, as the acquisition does not meet the jurisdictional criteria under the EU Merger Regulation or under the national merger control laws of any Member State of the European Union. On July 13, 2022, the EU General Court reached a decision in favor of the European Commission, holding that the European Commission has jurisdiction under the EU Merger Regulation to review the acquisition. On September 22, 2022, we filed an appeal in the Court of Justice of the European Union (the EU Court of Justice) asking for annulment of the EU General Court’s judgment.
On October 12, 2023, the European Commission adopted a decision requiring Illumina to unwind its acquisition of GRAIL (the EC Divestment Decision). On December 17, 2023, we announced that we would divest GRAIL. On June 24, 2024, we completed the separation (the Spin-Off) of GRAIL into a separate, independent publicly traded company through the distribution of approximately 85.5% of the outstanding GRAIL common stock to Illumina stockholders on a pro rata basis.
On September 3, 2024, the EU Court of Justice ruled in our favor, confirming that the European Commission had unlawfully asserted jurisdiction over our acquisition of GRAIL, and hence annulling the EU General Court’s judgment and the European Commission’s decisions accepting the referral of the GRAIL acquisition for EU merger review (the EU Court of Justice Judgment). The EU Court of Justice Judgment concludes these proceedings and is not subject to further appeals. In view of this judgment, on September 6, 2024, the European Commission issued a decision (the Withdrawal Decision) withdrawing all of its prior decisions, including (1) its July 22, 2021 decision opening an investigation of Illumina’s proposed acquisition of GRAIL, (2) its September 6, 2022 decision prohibiting Illumina’s acquisition of GRAIL, (3) its October 29, 2021 and October 28, 2022 decisions concerning interim measures, (4) the EC Divestment Decision, and (5) its July 12, 2023 decision fining Illumina €432 million and GRAIL for closing the acquisition before approval by the European Commission. The Withdrawal Decision resolves all ongoing regulatory proceedings in the European Union. The European Commission has also been ordered to pay Illumina’s costs incurred in connection with the GRAIL-related proceedings before the EU Court of Justice and the EU General Court.
As a result of the European Commission withdrawing its previously imposed fine, we recognized a net gain of $481 million in Q3 2024. We recognized a gain of $489 million in operating expense, resulting from reversal of the accrued fine and related accrued interest, offset by a loss of $8 million, recognized in other expense, net, for the reversal of associated foreign currency fluctuations. The fine accrued interest at a rate of 5.5% per annum while it was outstanding. The guarantees we provided in October 2023 to satisfy the obligation in lieu of cash payment while we appealed the European Commission’s jurisdictional and fine decisions are no longer outstanding.
On August 15, 2024, the U.S. Federal Trade Commission dismissed the previously disclosed administrative complaint in light of the completion of the Spin-Off.
SEC Inquiry Letter
In July 2023, we were informed that the staff of the SEC was conducting an investigation relating to Illumina and was requesting documents and communications primarily related to Illumina’s acquisition of GRAIL and certain statements and disclosures concerning GRAIL, its products and its acquisition, and related to the conduct and compensation of certain members of Illumina and GRAIL management, among other things. Illumina is cooperating with the SEC in this investigation.
Shareholder Derivative Complaints
On October 17, 2023, a stockholder derivative and class action complaint captioned Icahn Partners LP, et al. v. deSouza, et al., purportedly brought on behalf of Illumina and public holders of Illumina’s common stock, was filed in the Delaware Court of Chancery against certain current and former directors (including our former Chief Executive Officer). We are named as a nominal defendant in the complaint. The lawsuit alleges the named directors breached their fiduciary duties by knowingly causing Illumina to unlawfully close the GRAIL acquisition, concealing material facts related to the GRAIL acquisition and making inadequate disclosures. Before the filing of the complaint, the purported stockholders did not make a demand that our Board of Directors pursue the claims asserted therein. The complaint seeks damages, costs and expenses, including attorney fees, the certification and consolidation of a putative class, the issuance of amended disclosures, the removal of conflicted directors and declaratory and other equitable relief.
On November 1, 2023, the defendants filed a motion to dismiss the complaint, which has not yet been briefed. On the same day, Illumina-joined by the director defendants-moved to strike portions of the complaint that contain improperly included confidential and privileged information. On January 16, 2024, the Court granted the motion to strike. On December 5, 2023, the plaintiffs moved to expedite the proceedings with respect to their direct claims. The director defendants opposed that motion and Illumina joined their opposition. On January 19, 2024, the Court denied plaintiffs’ motion to expedite. On January 23, 2024, the plaintiffs filed a motion for reargument of the Court’s January 16 opinion, which the Court denied on February 19, 2024. On February 29, 2024, the plaintiffs filed an application to the trial court to certify the orders granting the motion to strike and denying the motion for reargument for interlocutory appeal. The Court refused the application on March 20, 2024. On March 14, 2024, the plaintiffs filed an application for interlocutory appeal with the Supreme Court of Delaware, which the Court denied on April 11, 2024.
On February 26, 2024, a stockholder derivative complaint captioned City of Omaha Police and Firefighters Retirement System v. deSouza, et al., purportedly brought on behalf of Illumina, was filed in the Delaware Court of Chancery against certain current and former directors. On April 16, 2024, a stockholder derivative complaint captioned City of Roseville General Employees Retirement System, et al. v. deSouza, et al., purportedly brought on behalf of Illumina, was filed in the Delaware Court of Chancery against certain current and former directors and officers. On August 16, 2024, a stockholder derivative complaint captioned Thomas P. DiNapoli v. John Thompson et al., purportedly brought on behalf of Illumina, was filed in the Delaware Court of Chancery against certain current and former directors. We are named as a nominal defendant in the complaints. The lawsuits allege the named directors and officers breached their fiduciary duties by knowingly causing Illumina to unlawfully close the GRAIL acquisition. The stockholders previously made requests to inspect certain books and records under Delaware law, and they purport to base their complaint in part on documents obtained from Illumina in response to those requests. Before the filing of the complaint, the purported stockholders did not make a demand that our Board of Directors pursue the claim asserted therein. The complaints seek damages against the individual defendants, costs and expenses, including attorney fees and other equitable relief.
On March 26, 2024, the defendants filed a motion to dismiss the complaint in the lawsuit filed by City of Omaha Police and Firefighters Retirement System. The motion has not yet been briefed. On May 16, 2024, the defendants filed a motion to dismiss the complaint in the lawsuit filed by City of Roseville General Employees Retirement System, et al. The motion has not yet been briefed. On September 16, 2024, the defendants filed a motion to dismiss the complaint in the lawsuit filed by Thomas DiNapoli. The motion has not yet been briefed.
On December 23, 2024, a stockholder derivative complaint captioned The Pavers and Road Builders Benefit Funds v. deSouza, et al., purportedly brought on behalf of Illumina, was filed in the Delaware Court of Chancery against certain current and former directors and officers. Like the complaints described above, the lawsuits allege the named directors and officers breached their fiduciary duties by knowingly causing Illumina to unlawfully close the GRAIL acquisition. The stockholder previously made requests to inspect certain books and records under Delaware law and litigated a books and records action against the Company (described below), and it purports to base its complaint in part on documents obtained from Illumina in response to those requests and that litigation. Before the filing of the complaint, the purported stockholder did not make a demand that our Board of Directors pursue the claim asserted therein. The complaint seeks damages against the individual defendants and other equitable relief.
In light of the fact that these lawsuits are in an early stage, we cannot predict the ultimate outcome of the suits. We deny the allegations in the complaints and intend to vigorously defend the litigations.
On February 21, 2024, a stockholder derivative complaint captioned Elaine Wang, et al. v. deSouza, et al., purportedly brought on behalf of the Company was filed in the United States District Court for the District of Delaware (District of Delaware) against certain current and former directors. The Company was named as a nominal defendant in the complaint. The lawsuit alleged that the named directors breached their fiduciary duties by knowingly causing the Company to unlawfully close the GRAIL acquisition. Before the filing of the complaint, the purported stockholder did not make a demand that our Board of Directors pursue the asserted claims therein. The complaint sought, among other things, restitution to the Company for the alleged damages caused by the named defendants.
On March 8, 2024, a stockholder derivative complaint captioned Michael Warner, et al. v. deSouza, et al., purportedly brought on behalf of Illumina was also filed in the United States District Court for the Southern District of California against certain current and former directors. We were named as a nominal defendant in the complaint. The lawsuit alleged that the named directors breached their fiduciary duties by knowingly causing us to unlawfully close the GRAIL acquisition. Before the filing of the complaint, the purported stockholder did not make a demand that our Board of Directors pursue the asserted claims therein. The complaint sought, among other things, restitution to Illumina for the alleged damages caused by the named defendants. On March 28, 2024, the parties submitted a Joint Motion to Transfer the lawsuit to the District of Delaware, which the Court granted on March 29, 2024, and the Court transferred the lawsuit to the District of Delaware on the same day.
Elaine Wang, et al. v. deSouza, et al. and Michael Warner, et al. v. deSouza, et al. were voluntarily dismissed on April 29, 2024, and May 1, 2024, respectively. On May 1, 2024, Michael Warner sent a litigation demand to our Board of Directors requesting that a civil action for monetary damages be brought by the Board of Directors on behalf of Illumina against officers and directors involved with the GRAIL acquisition. On July 30, 2024, the Board unanimously determined that it was in the best interest of the Company and its shareholders to defer a final decision on the demand given, among other things, the pending stockholder lawsuits described herein and the similarity of issues raised in the demand and those lawsuits. Our Board will monitor the stockholder lawsuits and revisit the demand as warranted as the lawsuits progress. On June 3, 2024, Elaine Wang made requests to inspect certain books and records under Delaware law and the Company sent a production of documents in response to that demand.
On August 21, 2024, an additional stockholder, Jane Davidson, sent a litigation demand to our Board of Directors requesting that a civil action for breaches of fiduciary duty, indemnification, contribution and other appropriate claims be brought by the Board of Directors on behalf of Illumina against officers and directors involved with the GRAIL acquisition. On October 29, 2024, the Board unanimously determined that it was in the best interest of the Company and its shareholders to defer a final decision on the demand given, among other things, the pending stockholder lawsuits described herein and the similarity of issues raised in the demand and those lawsuits. Our Board will monitor the stockholder lawsuits and revisit the demand as warranted as the lawsuits progress.
Securities Class Actions
Federal Securities Class Actions. On November 11, 2023, the first of three securities class action complaints was filed against Illumina and certain of its current and former executive officers in the United States District Court for the Southern District of California. The first-filed case is captioned Kangas v. Illumina, Inc. et al., the second-filed case is captioned Roy v. Illumina, Inc. et al., and the third-filed case is captioned Louisiana Sheriffs’ Pension & Relief Fund v. Illumina, Inc. et al. (collectively, the Actions). The complaints generally allege, among other things, that defendants made materially false and misleading statements and omitted material facts relating to Illumina’s acquisition of GRAIL. The complaints seek unspecified damages, interest, fees, and costs. On January 9, 2024, four movants filed motions to consolidate the Actions and to appoint a lead plaintiff (Lead Plaintiff Motions). On April 11, 2024, the Court issued an order consolidating the Actions into a single action (captioned in re Illumina, Inc. Securities Litigation No. 23-cv-2082-LL-MMP), and appointed Universal-Investment-Gesellschaft mbH, UI BVK Kapitalverwaltungsgesellschaft mbH, and ACATIS Investment Kapitalverwaltungsgesellschaft mbH as lead plaintiffs (the Lead Plaintiffs). On June 21, 2024, the Lead Plaintiffs filed their consolidated amended complaint. The complaint alleges that Illumina and GRAIL and certain of their current and former directors and officers violated Sections 10(b) and 20(a) of the Securities Exchange Act and SEC Rule 10b-5 in connection with Illumina’s acquisition of GRAIL. On September 13, 2024, the Lead Plaintiffs filed a second amended consolidated complaint. On November 12, 2024, the Company and other defendants filed a motion to dismiss the second amended consolidated complaint. On December 20, 2024, the Lead Plaintiffs filed their opposition to the motion to dismiss. The defendants’ final reply brief was filed on February 3, 2025. No hearing date has been set.
State Securities Class Actions. On February 2, 2024, the first of two additional securities class actions was filed against Illumina, certain of its officers and directors, and several other individuals and entities in the Superior Court of the State of California, County of San Mateo, captioned Loren Scott Mar v. Illumina, et al. and Scott Zerzanek v. Illumina, Inc. et al. Both complaints generally allege, among other things, that defendants made materially false and misleading statements and omitted material facts in the November 2020 and February 2021 registration statements and prospectus relating to Illumina’s acquisition of GRAIL. The complaints seek unspecified damages, interest, fees, and costs. On March 29, 2024, the parties to the actions filed a Joint Stipulation to Consolidate the actions and to appoint co-lead counsel for plaintiffs, which the Court granted on April 5, 2024. On August 12, 2024, the Plaintiffs filed their consolidated complaint. On September 6, 2024, Illumina and the other named defendants filed a motion to stay the litigation. On October 4, 2024, the plaintiffs opposed the motion to stay. At a hearing held on December 6, 2024, the Court declined to stay the litigation. The defendants’ demurrer is due February 28, 2025. Plaintiffs’ oppositions to the demurrer are due April 30, 2025, and defendants’ final reply briefs are due May 30, 2025. A hearing is set for June 20, 2025.
In light of the fact that the lawsuits are in an early stage, we cannot predict the ultimate outcome of the suits. We deny the allegations in the complaints and intend to vigorously defend the litigation.
DOJ Civil Investigative Demand
On January 18, 2024, we received a civil investigative demand (CID) from the U.S. Department of Justice, requiring production of certain documents and information in the course of a False Claims Act investigation to determine whether there is or has been a violation of 31 U.S.C. § 3729. The False Claims Act investigation concerns allegations that the Company caused the submission of false claims to Medicare and other federal government programs because it misrepresented its compliance with cybersecurity requirements to the Food and Drug Administration and other federal agencies that purchase its devices. The Company is cooperating with the government.
Books and Records Action
On February 14, 2024, a stockholder filed a complaint in the Delaware Court of Chancery captioned Pavers and Road Builders Benefit Funds v. Illumina, Inc. seeking to inspect certain books and records related to the GRAIL transaction, including certain materials and minutes from meetings of our Board of Directors, which have been withheld because the Company contends they are non-responsive to the request or subject to the attorney-client privilege. Illumina previously provided documents to the stockholder in response to a demand made by letter under Delaware law, but the stockholder seeks additional and unredacted materials through this action. On March 11, 2024, Illumina filed an answer to the complaint, denying that the stockholder was entitled to inspection. We deny that the stockholder is entitled to review the documents and intend to vigorously defend the litigation. The trial took place on June 7, 2024. On July 16, 2024, the Court issued a decision requiring the Company to produce certain additional documents to plaintiff. On July 26, 2024, the stockholder filed a motion seeking in camera review of certain documents that the Company maintains are not subject to the Court’s July 16, 2024 order to produce documents. The Court granted the motion on August 19, 2024, and the Company filed the documents for in camera review on August 29, 2024. On October 7, 2024, the Court ruled that the Company need not produce the documents subject to the motion for in camera review because they are privileged under the attorney opinion work product doctrine. On December 11, 2024, the Court entered its final order and judgment. On December 23, 2024, the plaintiff in this action filed a derivative complaint, described above.
BGI Genomics Co. Ltd. and its Affiliates
As previously disclosed, we were engaged in litigation in various U.S. jurisdictions with BGI Genomics Co. Ltd (BGI) and certain of its affiliates, including Complete Genomics, Inc. (CGI) since June of 2019. On July 14, 2022, we entered into a Settlement and License Agreement with BGI and CGI (the Agreement). Pursuant to the terms of the Agreement, we agreed to pay CGI a one time payment of $325 million. We allocated the $325 million payment on a relative fair value basis, resulting in $180 million capitalized as an intangible asset in 2022 for the value of the license, which is amortized over a period of 6.5 years on a straight-line basis, $150 million allocated to the release of past damages claimed, and a $5 million gain for damages awarded to us. The fair value of the license was estimated using a discounted cash flow model, which included assumptions for projected revenues covered by the license, an estimated royalty rate and a discount rate. The fair value of the past damages claimed was estimated based on applicable historical revenues and an estimated royalty rate. These inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value.
v3.25.0.1
INCOME TAXES
12 Months Ended
Dec. 29, 2024
Income Tax Disclosure [Abstract]  
INCOME TAXES
10. INCOME TAXES
Loss before income taxes summarized by region was as follows:
In millions202420232022
United States$(1,834)$(1,735)$(4,942)
Foreign655 618 606 
Total loss before income taxes
$(1,179)$(1,117)$(4,336)
The provision for income taxes consisted of the following:
In millions202420232022
Current:   
Federal$6 $(5)$(11)
State18 27 
Foreign137 77 75 
Total current provision161 78 91 
Deferred:
Federal(59)(13)40 
State(56)(26)(47)
Foreign(2)(16)
Total deferred benefit(117)(34)(23)
Total tax provision$44 $44 $68 

The provision for income taxes reconciles to the amount computed by applying the federal statutory rate to loss before income taxes as follows:
In millions202420232022
Tax at federal statutory rate$(248)$(235)$(911)
State, net of federal benefit(38)(16)(9)
Research and other credits(32)(42)(46)
Change in valuation allowance29 48 62 
Impact of R&D expense capitalization52 86 87 
Impact of net operating losses on GILTI, U.S. foreign tax credits, and Pillar Two global minimum top-up tax
90 61 60 
Impact of foreign operations3 (50)(81)
Stock compensation16 31 20 
Accrual of European Commission fine(99)96 
Goodwill impairment308 149 822 
Impact of acquisition related items(46)(27)
Other9 (5)
Total tax provision$44 $44 $68 

We have elected to account for the global intangible low-taxed income (GILTI) as a period cost in our consolidated financial statements.

The impact of foreign operations primarily represents the difference between the actual provision for income taxes for our legal entities that operate in jurisdictions that have statutory tax rates that differ from the U.S. federal statutory tax rate of 21%. The most significant tax benefits from foreign operations were from our earnings in Singapore, which had a statutory tax rate of 17% in 2024. The impact of foreign operations also includes the impacts of GILTI, U.S. foreign tax credits, and the Pillar Two global minimum top-up tax of non-U.S. earnings before the tax impact of net operating losses, and uncertain tax positions related to foreign items.

The impact of R&D expense capitalization is primarily the income tax expense impact of capitalizing research and development expenses for tax purposes on GILTI and the utilization of the U.S. foreign tax credits.
The impact of net operating losses on GILTI, U.S. foreign tax credits, and the Pillar Two global minimum top-up tax is primarily the income tax expense impact of GRAIL pre-acquisition net operating losses on GILTI, the utilization of the U.S. foreign tax credits, and the Pillar Two global minimum top-up tax.

The impact of acquisition related items includes the income tax expense impact of transaction costs, acquisition related compensation, and changes to the contingent value rights associated with the GRAIL acquisition.

Significant components of deferred tax assets and liabilities were as follows:
In millionsDecember 29,
2024
December 31,
2023
Deferred tax assets:  
Net operating losses$189 $392 
Tax credits252 211 
Other accruals and reserves40 49 
Stock compensation34 15 
Capitalized U.S. R&D expenses181 158 
Other amortization42 115 
Operating lease liabilities112 146 
Property and equipment17 
Investments23 
Other63 56 
Total gross deferred tax assets953 1,153 
Valuation allowance on deferred tax assets(278)(251)
Total deferred tax assets
675 902 
Deferred tax liabilities:  
Purchased intangible amortization(35)(734)
Operating lease right-of-use assets(57)(88)
Other(25)(25)
Total deferred tax liabilities(117)(847)
Deferred tax assets, net$558 $55 

A valuation allowance is established when it is more likely than not the future realization of all or some of the deferred tax assets will not be achieved. The evaluation of the need for a valuation allowance is performed on a jurisdiction-by-jurisdiction basis and includes a review of all available positive and negative evidence, including operating results and forecasted ranges of future taxable income. Based on the available evidence as of December 29, 2024, we were not able to conclude it is more likely than not certain deferred tax assets will be realized. Therefore, a valuation allowance of $278 million was recorded against certain U.S. and foreign deferred tax assets.     

As of December 29, 2024, we had net operating loss carryforwards for federal and state tax purposes of $74 million and $1,872 million, respectively, which will begin to expire in 2036 and 2025, respectively, unless utilized prior. We also had federal and state tax credit carryforwards of $140 million and $239 million, which will begin to expire in 2031 and 2027, respectively, unless utilized prior.

Pursuant to Section 382 and 383 of the Internal Revenue Code, utilization of net operating losses and credits may be subject to annual limitations in the event of any significant future changes in its ownership structure. These annual limitations may result in the expiration of net operating losses and credits prior to utilization. The deferred tax assets as of December 29, 2024 are net of any previous limitations due to Section 382 and 383.

Our manufacturing operations in Singapore operate under various tax holidays and incentives, which will begin to expire in 2028. These tax holidays and incentives resulted in a $33 million, $75 million, and $56 million decrease to the provision for income taxes in 2024, 2023, and 2022, respectively. These tax holidays and incentives resulted in a decrease in diluted loss per share of $0.20, $0.47, and $0.35, in 2024, 2023, and 2022, respectively.
As of December 29, 2024, we asserted that $1,806 million of foreign earnings would not be indefinitely reinvested, and accordingly, recorded a deferred tax liability of $24 million.

The following table summarizes the gross amount of our uncertain tax positions:
In millionsDecember 29,
2024
December 31,
2023
January 1,
2023
Balance at beginning of year$210 $153 $131 
Increases related to prior year tax positions2 27 12 
Decreases related to prior year tax positions(2)(2)(3)
Increases related to current year tax positions23 42 42 
Decreases related to lapse of statute of limitations(1)(10)(29)
Balance at end of year$232 $210 $153 

Included in the balance of uncertain tax positions as of December 29, 2024 and December 31, 2023, was $202 million and $156 million, respectively, of net unrecognized tax benefits that, if recognized, would reduce the effective income tax rate in future periods.

Any interest and penalties related to uncertain tax positions are reflected in the provision for income taxes. We recognized expense of $6 million and $2 million in 2024 and 2023, respectively, and income of $3 million in 2022, related to potential interest and penalties on uncertain tax positions. We recorded a liability for potential interest and penalties of $13 million and $6 million as of December 29, 2024 and December 31, 2023, respectively.

Tax years 1997 to 2023 remain subject to future examination by the major tax jurisdictions in which we are subject to tax. The Internal Revenue Service completed an examination of the U.S. Corporation Income Tax Returns for tax years 2017, 2018, and 2020. Given the uncertainty of potential adjustments from examination as well as the potential expiration of the statute of limitations, it is reasonably possible that the balance of unrecognized tax benefits could change significantly over the next 12 months. Due to the number of years remaining that are subject to examination, we are unable to estimate the full range of possible adjustments to the balance of gross unrecognized tax benefits.
v3.25.0.1
EMPLOYEE BENEFIT PLANS
12 Months Ended
Dec. 29, 2024
Postemployment Benefits [Abstract]  
EMPLOYEE BENEFIT PLANS
11. EMPLOYEE BENEFIT PLANS
Retirement Plan
We have a 401(k) savings plan covering substantially all of our employees in the United States. Our contributions to the plan are discretionary. During 2024, 2023, and 2022, we made matching contributions of $34 million, $36 million, and $30 million, respectively.

Deferred Compensation Plan
The Illumina, Inc. Deferred Compensation Plan (the Plan) allows senior level employees to contribute up to 60% of their base salary and 100% of their variable cash compensation, and members of the board of directors to contribute up to 100% of their director fees and equity awards. Under the Plan, we credit the participants’ contributions with earnings that reflect the performance of certain independent investment funds. On a discretionary basis, we may also make employer contributions to participant accounts in any amount determined by us. The vesting schedules of employer contributions are at the sole discretion of the Compensation Committee. However, all employer contributions shall become 100% vested upon the occurrence of the participant’s disability, death or retirement or a change in control of Illumina. The benefits under this plan are unsecured. Participants are generally eligible to receive payment of their vested benefit at the end of their elected deferral period or after termination of their employment for any reason or at a later date to comply with the restrictions of Section 409A.
We established a rabbi trust for the benefit of the participants under the Plan and have included the assets of the rabbi trust in other assets in the consolidated balance sheets. As of December 29, 2024 and December 31, 2023, the assets of the trust were $70 million and $61 million, respectively, and our liabilities, included in accrued liabilities, were $65 million and $59 million, respectively. Changes in the values of the assets held by the trust are recorded in other expense, net, and changes in the values of the deferred compensation liabilities are recorded in operating expense.
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION
12 Months Ended
Dec. 29, 2024
Segment Reporting [Abstract]  
SEGMENT AND GEOGRAPHIC INFORMATION
12. SEGMENT AND GEOGRAPHIC INFORMATION
Reportable Segment Information
As of December 29, 2024, we have one reportable segment, Core Illumina. Prior to the Spin-Off of GRAIL, on June 24, 2024, our reportable segments included both Core Illumina and GRAIL. See note 2. GRAIL Spin-Off for details. We continue to disclose certain historical information for GRAIL prior to the Spin-Off. Segment information is consistent with how our Chief Operating Decision Maker (CODM), who is our Chief Executive Officer, reviews financial information, makes operating decisions, allocates resources, and assesses performance. We also consider the way budgets and forecasts are prepared and reviewed and the basis on which executive compensation is determined.
Core Illumina: Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina sells products and provides services to GRAIL, and vice versa, in accordance with contractual agreements between the entities.
GRAIL: GRAIL is a healthcare company focused on early detection of multiple cancers. Prior to the Spin-Off of GRAIL into a separate, independent public company, GRAIL was required to be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission.
Our CODM allocates resources and evaluates business performance based on revenues and net income (loss). Net income (loss) is used in the annual budgeting and monthly forecasting processes and to monitor and assess budgeted/forecasted versus actual results. Our CODM does not evaluate segments using asset information. The accounting policies for segments are the same as those described in the summary of significant accounting policies.
The following tables present selected financial information with respect to segments for the periods presented:
In millions202420232022
Core Illumina:
Revenue(1)
$4,332 $4,438 $4,553 
Less:
Cost of revenue1,424 1,582 1,446 
Research and development988 1,030 1,004 
Selling and marketing638 648 677 
General and administrative262 600 326 
Goodwill and intangible impairment
3 — 
Legal contingency and settlement
(456)20 619 
Core Illumina income from operations1,473 552 481 
GRAIL:
Revenue
55 93 55 
Total operating expenses(2)
2,360 1,714 4,712 
Consolidated other expense, net
346 48 157 
Consolidated provision for income taxes
44 44 68 
Intersegment eliminations
(1)— (3)
Consolidated net loss$(1,223)$(1,161)$(4,404)
_____________
(1)Core Illumina revenue for 2024, 2023, and 2022 included intercompany revenue of $15 million, $26 million, and $24 million, respectively.
(2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative periods prior to the Spin-Off on June 24, 2024.
 In millions202420232022
Depreciation and amortization:
Core Illumina$280 $273 $240 
GRAIL74 159 154 
Consolidated depreciation and amortization$354 $432 $394 
Capital expenditures:
Core Illumina$137 $183 $262 
GRAIL5 13 24 
Eliminations (1)— 
Consolidated capital expenditures$142 $195 $286 
Geographic Data
Long-lived assets, consisting of property and equipment and operating lease right-of-use assets, were as follows:
In millionsDecember 29,
2024
December 31,
2023
United States$750 $1,040 
Singapore279 298 
United Kingdom124 136 
Other countries81 77 
Total long-lived assets, net
$1,234 $1,551 
Refer to note 3. Revenue for revenue by geographic area.
v3.25.0.1
Pay vs Performance Disclosure - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Pay vs Performance Disclosure      
Net loss $ (1,223) $ (1,161) $ (4,404)
v3.25.0.1
Insider Trading Arrangements
3 Months Ended 12 Months Ended
Dec. 29, 2024
shares
Dec. 29, 2024
shares
Trading Arrangements, by Individual    
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Frances Arnold [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 6, 2024, Frances Arnold, a member of our Board of Directors, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on February 27, 2026 and provides for the sale of up to 120 shares.
Name Frances Arnold  
Title Board of Directors  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 6, 2024  
Expiration Date February 27, 2026  
Arrangement Duration 478 days  
Aggregate Available 120 120
Jakob Wedel [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 7, 2024, Jakob Wedel, our Chief Strategy and Corporate Development Officer, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on May 29, 2026 and provides for the sale of up to 3,182 shares.
Name Jakob Wedel  
Title Chief Strategy and Corporate Development Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 7, 2024  
Expiration Date May 29, 2026  
Arrangement Duration 568 days  
Aggregate Available 3,182 3,182
Scott Davies [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 8, 2024, Scott Davies, our Interim General Counsel, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on December 16, 2025 and provides for the sale of up to 3,301 shares.
Name Scott Davies  
Title Interim General Counsel  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 8, 2024  
Expiration Date December 16, 2025  
Arrangement Duration 403 days  
Aggregate Available 3,301 3,301
Patricia Leckman [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 13, 2024, Patricia Leckman, our Chief People Officer, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on November 14, 2025 and provides for the sale of up to 1,615 shares.
Name Patricia Leckman  
Title Chief People Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 13, 2024  
Expiration Date November 14, 2025  
Arrangement Duration 366 days  
Aggregate Available 1,615 1,615
v3.25.0.1
Insider Trading Policies and Procedures
12 Months Ended
Dec. 29, 2024
Insider Trading Policies and Procedures [Line Items]  
Insider Trading Policies and Procedures Adopted true
v3.25.0.1
Cybersecurity Risk Management and Strategy Disclosure
12 Months Ended
Dec. 29, 2024
Cybersecurity Risk Management, Strategy, and Governance [Line Items]  
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
We recognize the importance of developing, implementing, and maintaining robust cybersecurity measures to safeguard our information systems and protect the confidentiality, integrity, and availability of our data. Our cybersecurity risk management strategy is integrated into our established enterprise risk management program, which includes defined risk, assessment, mitigation, and reporting processes. Our information security team has deployed multiple technical and operational processes to aid in our ability to continuously identify and respond to cybersecurity threats and incidents. Our cybersecurity incident management process includes impact assessment, containment, mitigation and recovery strategies.
In addition to our continuous monitoring of our information systems, we utilize third parties to provide external threat intelligence and evaluation of incident notifications in order to identify potential threats or incidents that could impact us. We also evaluate our cybersecurity program against the National Institute of Standards and Technology’s Cybersecurity Framework. For all suspected cybersecurity incidents, the information security team conducts a preliminary assessment to determine the potential severity and impact extent of the incident and, where appropriate, a materiality assessment is made. Upon a confirmed cybersecurity incident, the information security team initiates an incident response process with goals to contain, respond, recover, protect and minimize any impacts caused by the incident. The response process includes deployment of a variety of short term and long-term technical and procedural actions as appropriate. Further, we have established a third party risk management program to monitor suppliers who have access to our information.
Cybersecurity Risk Management Processes Integrated [Flag] true
Cybersecurity Risk Management Processes Integrated [Text Block] Our cybersecurity risk management strategy is integrated into our established enterprise risk management program, which includes defined risk, assessment, mitigation, and reporting processes.
Cybersecurity Risk Management Third Party Engaged [Flag] true
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag] true
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag] false
Cybersecurity Risk Board of Directors Oversight [Text Block]
Our Audit Committee, a committee of our Board of Directors, is responsible for governing management’s review and assessment of our cybersecurity and other information technology risks, controls, and procedures, including management’s incident resolution process and any specific cybersecurity issues that could affect the adequacy of our internal controls. Our Chief Information Officer provides regular updates to the Audit Committee and to the Board of Directors, including a review of any security risk events and improvements in our security controls.
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block] Our Audit Committee, a committee of our Board of Directors, is responsible for governing management’s review and assessment of our cybersecurity and other information technology risks, controls, and procedures, including management’s incident resolution process and any specific cybersecurity issues that could affect the adequacy of our internal controls.
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block] Our Chief Information Officer provides regular updates to the Audit Committee and to the Board of Directors, including a review of any security risk events and improvements in our security controls.
Cybersecurity Risk Role of Management [Text Block]
Our information security team, under the Chief Information Officer, is led by our Chief Information Security Officer (CISO) and is responsible for assessing and managing risks from cybersecurity threats. Our CISO has over 20 years of information security experience, including as a leader of information security programs at other large enterprises, and is supported by a team of professionals focused on information security. Our information security team regularly meets to review our cybersecurity posture, the broader cybersecurity landscape and any identified cybersecurity incidents. Our information security team has procedures in place for investigating suspected cybersecurity incidents, as well as monitoring cybersecurity risks and ongoing mitigation strategies, the status of prevention, detection, and mitigation controls and any planned future control enhancements.
We believe that risks from prior cybersecurity threats to information systems owned and used by us, including as a result of any previous cybersecurity incidents, have not materially affected our business to date. We can provide no assurance that there will not be incidents in the future or that they will not materially affect us, including our business strategy, results of operations, or financial condition. We maintain a cybersecurity insurance policy which may mitigate certain financial impacts of a cybersecurity incident. Please refer to “Risks Relating to Information Technology Security and Continuity” within the Risk Factors within the Business & Market Information Section of this report.
Cybersecurity Risk Management Positions or Committees Responsible [Flag] true
Cybersecurity Risk Management Positions or Committees Responsible [Text Block] Our information security team, under the Chief Information Officer, is led by our Chief Information Security Officer (CISO) and is responsible for assessing and managing risks from cybersecurity threats.
Cybersecurity Risk Management Expertise of Management Responsible [Text Block] Our CISO has over 20 years of information security experience, including as a leader of information security programs at other large enterprises, and is supported by a team of professionals focused on information security.
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Our Audit Committee, a committee of our Board of Directors, is responsible for governing management’s review and assessment of our cybersecurity and other information technology risks, controls, and procedures, including management’s incident resolution process and any specific cybersecurity issues that could affect the adequacy of our internal controls. Our Chief Information Officer provides regular updates to the Audit Committee and to the Board of Directors, including a review of any security risk events and improvements in our security controls.
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag] true
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES (Policies)
12 Months Ended
Dec. 29, 2024
Accounting Policies [Abstract]  
Basis of Presentation
Basis of Presentation
The consolidated financial statements have been prepared in conformity with U.S. generally accepted accounting principles (GAAP) and include our accounts, our wholly-owned subsidiaries, and majority-owned or controlled companies. All intercompany transactions and balances have been eliminated in consolidation. Certain prior period amounts have been reclassified to conform to the current period presentation.
Variable Interest Entities (VIEs)
Variable Interest Entities (VIEs)
We evaluate our ownership, contractual and other interests in entities that are not wholly-owned to determine if these entities are VIEs, and, if so, whether we are the primary beneficiary of the VIE. In determining whether we are the primary beneficiary of a VIE and therefore required to consolidate the VIE, we apply a qualitative approach that determines whether we have both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. We continuously perform this assessment, as changes to existing relationships or future transactions may result in the consolidation or deconsolidation of a VIE. As of December 29, 2024, there were no VIEs for which we were the primary beneficiary and for which we were required to consolidate.
Use of Estimates
Use of Estimates
The preparation of the consolidated financial statements requires that management make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses, and related disclosures of contingent assets and liabilities. Though macroeconomic factors such as inflation, exchange rate fluctuations and concerns about an economic downturn present additional uncertainty, we continue to use the best information available to inform our critical accounting estimates. Actual results could differ from those estimates.
Fiscal Year
Fiscal Year
Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. References to 2024, 2023, and 2022 refer to fiscal years ended December 29, 2024, December 31, 2023, and January 1, 2023, respectively, which were all 52 weeks.
Functional Currency
Functional Currency
The U.S. dollar is the functional currency of our international operations. We re-measure foreign subsidiaries’ monetary assets and liabilities to the U.S. dollar and record the net gains or losses resulting from re-measurement in other expense, net in the consolidated statements of operations.
Concentrations of Risk
Concentrations of Risk
Customers
We operate in markets that are highly competitive and rapidly changing. Significant technological changes, shifting customer needs, the emergence of competitive products or services with new capabilities, and other factors could negatively impact our operating results. A portion of our customers consist of university and research institutions that management believes are, to some degree, directly or indirectly supported by the United States Government. A significant change in current research funding, particularly with respect to funding of the U.S. National Institutes of Health or targeted cancellations by the U.S. federal government of certain grants or contracts, could have an adverse impact on future revenues and results of operations.
International sales entail a variety of risks, including currency exchange fluctuations, longer payment cycles, and greater difficulty in accounts receivable collection. We are also subject to general geopolitical risks, such as political, social and economic instability, and changes in diplomatic and trade relations. The risks of international sales are mitigated in part by the extent to which sales are geographically distributed. Shipments to customers outside the United States comprised 48%, 48%, and 50% of total consolidated revenue in 2024, 2023, and 2022, respectively. Customers outside the United States represented 53% and 55% of our gross trade accounts receivable balance as of December 29, 2024 and December 31, 2023, respectively.
We had no customers that provided more than 10% of total consolidated revenue in 2024, 2023, and 2022. We perform regular reviews of customer activity and associated credit risks and do not require collateral or enter into netting arrangements. Historically, we have not experienced significant credit losses from accounts receivable.
Financial Instruments
We are also subject to risks related to our financial instruments, including cash and cash equivalents, investments, and accounts receivable. Most of our cash and cash equivalents as of December 29, 2024 were deposited with U.S. financial institutions, either domestically or with their foreign branches. Our investment policy restricts the amount of credit exposure to any one issuer to 5% of the portfolio or 5% of the total issue size outstanding at the time of purchase and to any one industry sector, as defined by Clearwater Analytics (Industry Sector Report), to 30% of the portfolio at the time of purchase. There is no limit to the percentage of the portfolio that may be maintained in debt securities, U.S. government-sponsored entities, U.S. Treasury securities, and money market funds. Historically, we have not experienced significant credit losses from financial instruments.
Suppliers
We require customized products and components that currently are available from a limited number of sources. We source certain key products and components included in our products from single vendors. Historically, we have not experienced significant issues sourcing materials to build our products.
Segments
Segments
We report segment information based on the management approach, which designates the internal reporting used by the Chief Operating Decision Maker (CODM) for making decisions and assessing performance as the source of our reportable segments. Our CODM allocates resources and assesses the performance of segments using information about their revenue and net income (loss). Our CODM does not evaluate our segments using asset information.
Accounting Pronouncements Adopted and Accounting Pronouncements Pending Adoption
Accounting Pronouncements Adopted in 2024
In December 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280) - Improvements to Reportable Segment Disclosures. The new standard requires a company to disclose incremental segment information on an annual and interim basis, including significant segment expenses and measures of profit or loss that are regularly provided to the CODM. The standard does not change how an entity identifies its operating segments. The standard was effective for us beginning in fiscal year 2024 and interim periods within fiscal year 2025. We adopted the standard on its effective date in fiscal year 2024 and applied the amendments retrospectively to all prior periods presented in the consolidated financial statements. See note 12. Segment and Geographic Information for additional details.
Accounting Pronouncements Adopted in 2022
In August 2020, the FASB issued ASU 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity’s Own Equity (Subtopic 815-40). The new standard reduces the number of accounting models for convertible debt instruments, amends the accounting for certain contracts in an entity’s own equity, and modifies how certain convertible instruments and contracts that may be settled in cash or shares impact the calculation of diluted earnings per share. Specifically, the guidance removes certain accounting models that separate the embedded conversion features from the host contract for convertible instruments and requires the use of the if-converted method to calculate diluted earnings per share. We adopted the standard on its effective date in the first quarter of 2022 using a modified retrospective approach by recognizing a cumulative-effect adjustment to retained earnings on January 3, 2022. As a result of the adoption of ASU 2020-06, we increased retained earnings and decreased additional paid-in capital by $61 million and $93 million, respectively.
Accounting Pronouncements Pending Adoption
In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses - Income Statement - Reporting Comprehensive Income - Expense Disaggregation Disclosures (Subtopic 220-40). The new standard requires a company to provide disaggregated disclosures, in the notes to the financial statements, of specified categories of expenses that are included in line items on the face of the income statement. The standard is effective for us beginning in fiscal year 2027 and interim periods within fiscal year 2028, with early adoption permitted. The new standard is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2024-03 on the consolidated financial statements and related disclosures.
In December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740) - Improvements to Income Tax Disclosures. The new standard requires a company to expand its existing income tax disclosures, specifically related to the rate reconciliation and income taxes paid. The standard is effective for us beginning in fiscal year 2025, with early adoption permitted, and is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2023-09 on the consolidated financial statements and related disclosures.
Revenue Recognition and Shipping and Handling Expenses
Revenue Recognition
Our revenue is generated from the sale of products and services. Product revenue consists of sales of instruments and consumables used in genetic analysis. Service and other revenue consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and, prior to the Spin-Off of GRAIL on June 24, 2024, cancer detection testing services related to the GRAIL business.
We recognize revenue when control of our products and services is transferred to our customers in an amount that reflects the consideration we expect to receive from our customers in exchange for those products and services. This process involves identifying the contract with a customer, determining the performance obligations in the contract, determining the contract price, allocating the contract price to the distinct performance obligations in the contract, and recognizing revenue when the performance obligations have been satisfied. Revenue recognition for contracts with multiple deliverables is based on the separate satisfaction of each distinct performance obligation within the contract. A performance obligation is considered distinct from other obligations in a contract when it provides a benefit to the customer either on its own or together with other resources that are readily available to the customer and is separately identified in the contract. We consider a performance obligation satisfied once we have transferred control of a good or service to the customer, meaning the customer has the ability to use and obtain the benefit of the good or service. The contract price is allocated to each performance obligation in proportion to its standalone selling price. We determine our best estimate of standalone selling price using average selling prices over a rolling 12-month period coupled with an assessment of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, we rely upon prices set by management, adjusted for applicable discounts.
Revenue from product sales is recognized generally upon delivery to the end customer, which is when control of the product is deemed to be transferred. Invoicing typically occurs upon shipment and payment is typically due within 30 days from invoice. In instances where right of payment or transfer of title is contingent upon the customer’s acceptance of the product, revenue is deferred until all acceptance criteria have been met. Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer. Revenue from instrument service contracts is recognized as the services are rendered, typically evenly over the contract term. Revenue from development and licensing agreements generally includes upfront and periodic licensing fees, contract research and development services, or payments for development and regulatory milestones. Revenue for these agreements is recognized when each distinct performance obligation is satisfied.
Revenue is recorded net of discounts, distributor commissions, and sales taxes collected on behalf of governmental authorities. Employee sales commissions are recorded as selling, general and administrative expense when incurred as the amortization period for such costs, if capitalized, would have been one year or less.
In certain markets, products and services are sold to customers through distributors. In most sales through distributors, the product is delivered directly to customers by us. The terms of sales transactions through distributors are consistent with the terms of direct sales to customers.
Shipping and Handling Expenses
Shipping and handling expenses are included in cost of product revenue.
(Loss) Earnings per Share
Loss per Share
Basic loss per share is computed based on the weighted average number of common shares outstanding during the period. Diluted loss per share is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. In loss periods, basic and diluted loss per share are identical since the effect of potentially dilutive common shares is antidilutive and therefore excluded. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares. Potentially dilutive common shares issuable upon conversion of convertible senior notes are determined using the if-converted method.
Fair Value Measurements
Fair Value Measurements
The fair value of assets and liabilities are based on the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value maximize use of observable inputs and minimize use of unobservable inputs. We use a fair value hierarchy with three levels of inputs, of which the first two are considered observable and the last unobservable, to measure fair value:
Level 1 — Quoted prices in active markets for identical assets or liabilities.
Level 2 — Inputs, other than Level 1, that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.
The carrying amounts of financial instruments such as cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable, and accrued liabilities approximate the related fair values due to the short-term maturities of these instruments.
Cash Equivalents
Cash Equivalents and Investments
Cash equivalents are comprised of short-term, highly-liquid investments with original maturities of 90 days or less.
Equity Securities and Investments
We have strategic investments in privately-held companies (non-marketable equity securities) and publicly traded companies (marketable equity securities). Our marketable equity securities are measured at fair value. Our non-marketable equity securities without readily determinable market values are initially measured at cost and adjusted to fair value for observable transactions for identical or similar investments of the same issuer or impairment. Equity investments are classified as current, short-term investments, or noncurrent, recorded in other assets, based on the nature of the securities and their availability for use in current operations. Realized and unrealized gains and losses on our equity investments are recorded in other expense, net in the consolidated statements of operations. Our equity investments are assessed for impairment quarterly. Impairment losses, equal to the difference between the carrying value and the fair value of the investment, are recorded in other expense, net.
We use the equity method to account for investments through which we have the ability to exercise significant influence, but not control, over the investee. Such investments are recorded in other assets, and our share of net income or loss is recognized on a one quarter lag in other expense, net.
Accounts Receivable
Accounts Receivable
Trade accounts receivable are recorded at the net invoice value and are not interest-bearing. Receivables are considered past due based on the contractual payment terms. We reserve a percentage of our trade receivable balance based on collection history and current economic trends that we expect will impact the level of credit losses over the life of our receivables. These reserves are re-evaluated on a regular basis and adjusted, as needed. Once a receivable is deemed to be uncollectible, such balance is charged against the reserve.
Inventory
Inventory
Inventory is stated at the lower of cost or net realizable value, on a first-in, first-out basis. Inventory includes raw materials and finished goods that may be used in the research and development process, and such items are expensed as consumed or capitalized as property and equipment and depreciated. Inventory write-downs for slow-moving, excess, and obsolete inventories are estimated based on product life cycles, quality issues, historical experience, and usage forecasts.
Property and Equipment
Property and Equipment
Property and equipment are stated at cost, subject to review for impairment, and depreciated over the estimated useful lives of the assets, using the straight-line method. Depreciation of leasehold improvements is recorded over the shorter of the lease term or the estimated useful life of the related assets. Maintenance and repairs are expensed as incurred. When assets are sold, or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and any gain or loss is included in operating expense.
Costs incurred to develop internal-use software during the application development stage are recorded at cost as computer software. Costs incurred in the development of such internal-use software, including external direct costs of materials and services and applicable compensation costs of employees devoted to specific software application development, are capitalized. Costs incurred outside of the application development stage are expensed as incurred.
Leases
Leases
We have various non-cancellable operating lease agreements for office, lab, manufacturing, and distribution facilities. These leases have remaining lease terms of 1 year to 14 years, which represent the non-cancellable periods of the leases and include extension options that we determined are reasonably certain to be exercised. We exclude extension options that are not reasonably certain to be exercised from our lease terms, ranging from 2 years to 20 years. Our lease payments consist primarily of fixed rental payments for the right to use the underlying leased assets over the lease terms, as well as payments for common-area-maintenance and administrative services. We often receive customary incentives from our landlords, such as reimbursements for tenant improvements and rent abatement periods, which effectively reduce the total lease payments owed for these leases. Leases are classified as operating or financing at commencement. As of December 29, 2024, we do not have any financing leases.
Operating lease right-of-use assets and liabilities on our consolidated balance sheets represent the present value of our remaining lease payments over the remaining lease terms, less any impairments recorded for right-of-use assets. We do not allocate lease payments to non-lease components; therefore, fixed payments for common-area-maintenance and administrative services are included in our operating lease right-of-use assets and liabilities. We use our incremental borrowing rate to calculate the present value of our lease payments, as the implicit rates in our leases are not readily determinable. Operating lease costs consist primarily of the fixed lease payments included in our operating lease liabilities and are recorded on a straight-line basis over the lease terms. We sublease certain real estate to third parties and this sublease income is also recorded on a straight-line basis.
Business Combinations
Business Combinations
Under the acquisition method of accounting, we allocate the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. These valuations require us to make estimates and assumptions, especially with respect to intangible assets. We record the excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, as goodwill. Costs that we incur to complete the business combination, such as legal and other professional fees, are expensed as they are incurred.
In connection with certain acquisitions, contingent consideration can be earned by the sellers upon completion of certain future performance milestones. In these cases, a liability is recorded on the acquisition date, as a component of accrued liabilities and/or other long-term liabilities, for an estimate of the acquisition-date fair value of the contingent consideration. These estimates require management judgment, including probabilities of achieving certain future milestones. Changes in the fair value of the contingent consideration subsequent to the acquisition date are recognized in selling, general and administrative expense in our consolidated statements of operations.
If the initial accounting for a business combination is incomplete by the end of a reporting period that falls within the measurement period (not to exceed a year from the date of acquisition), we report provisional amounts in our financial statements. During the measurement period, we adjust the provisional amounts recognized at the acquisition date to reflect new information obtained about facts and circumstances that existed as of the acquisition date that, if known, would have affected the measurement of the amounts recognized as of that date. We record these adjustments to the provisional amounts with a corresponding offset to goodwill. Any adjustments identified after the measurement period are recorded in the consolidated statements of operations.
Goodwill, Intangible Assets and Other Long-Lived Assets
Goodwill, Intangible Assets and Other Long-Lived Assets
Assets acquired, including intangible assets and capitalized in-process research and development (IPR&D), and liabilities assumed are measured at fair value as of the acquisition date. Goodwill, which has an indefinite useful life, represents the excess of cost over fair value of the net assets acquired. Intangible assets acquired in a business combination that are used for IPR&D activities are considered indefinite lived until the completion or abandonment of the associated research and development efforts. Upon reaching the end of the relevant research and development project (i.e., upon commercialization), the IPR&D asset is amortized over its estimated useful life. If the relevant research and development project is abandoned, the IPR&D asset is expensed in the period of abandonment.
Goodwill and IPR&D are not amortized; however, they are reviewed for impairment at least annually during the second quarter, or more frequently if an event occurs indicating the potential for impairment. Goodwill and IPR&D are considered to be impaired if the carrying value of the reporting unit or IPR&D asset exceeds its respective fair value.
We perform our goodwill impairment analysis at the reporting unit level, which aligns with our reporting structure and availability of discrete financial information. During the goodwill impairment review, we assess qualitative factors to determine whether it is more likely than not that the fair values of our reporting units are less than the carrying amounts, including goodwill. The qualitative factors include, but are not limited to, macroeconomic conditions, industry and market considerations, and our overall financial performance. If, after assessing the totality of these qualitative factors, we determine that it is not more likely than not that the fair values of our reporting units are less than the carrying amounts, then no additional assessment is deemed necessary. Otherwise, we proceed to compare the estimated fair values of the reporting units with the carrying values, including goodwill. If the carrying amount of a reporting unit exceeds its fair value, we record an impairment loss based on the difference. We may elect to bypass the qualitative assessment in a period and proceed to perform the quantitative goodwill impairment test.
The IPR&D impairment test is performed by comparing the fair value of the asset to its carrying amount. When testing indefinite-lived intangibles for impairment, we may assess qualitative factors to determine whether it is more likely than not that the asset is impaired. Alternatively, we may bypass this qualitative assessment and perform a quantitative impairment test. If the IPR&D asset is impaired, the carrying value of the IPR&D is written down to the revised fair value with the related impairment charge recognized in the period in which the impairment occurs.
Our identifiable intangible assets with a finite life are typically comprised of acquired developed technologies, licensed technologies, customer relationships, license agreements, and trade names. The cost of identifiable intangible assets with finite lives is generally amortized on a straight-line basis over the assets’ respective estimated useful lives.
We perform regular reviews to determine if any event has occurred that may indicate that intangible assets with finite useful lives and other long-lived assets are potentially impaired. If indicators of impairment exist, an impairment test is performed to assess the recoverability of the affected assets by determining whether the carrying amount of such assets exceeds the undiscounted expected future cash flows. If the affected assets are not recoverable, we estimate the fair value of the assets and record an impairment loss in an amount equal to the excess of the carrying value over the fair value. Factors that may indicate potential impairment include a significant decline in our stock price and market capitalization compared to the net book value, significant changes in the ability of a particular asset to generate positive cash flows for our strategic business objectives, and the pattern of utilization of a particular asset.
We review our operating lease right-of-use assets for impairment whenever events or changes in circumstances indicate the carrying value of the right-of-use asset may not be recoverable. The evaluation is performed at the lowest level for which identifiable cash flows are largely independent of the cash flows of other groups of assets and liabilities. We consider a triggering event to reassess a right-of-use asset’s asset group to have occurred if we exit a portion of or the full facility or enter into a sublease. Factors that may indicate potential impairment include a significant decrease in the market price of an underlying leased asset group. If we conclude the carrying value of affected assets will not be recovered, we estimate the fair value of the assets and record an impairment in an amount equal to the excess of the carrying value over the fair value.
Derivative Financial Instruments
Derivative Financial Instruments
We are exposed to foreign exchange rate risks in the normal course of business and use derivative financial instruments to partially offset this exposure. We do not use derivative financial instruments for speculative or trading purposes. Foreign exchange contracts are carried at fair value in other current assets, other assets, accrued liabilities, or other long-term liabilities, as appropriate, on the consolidated balance sheets. The cash flows associated with such foreign exchange contracts, or derivative financial instruments, are classified as cash flows from operating activities in the consolidated statements of cash flows, which is the same category as the hedged transaction.
We use foreign exchange forward contracts to manage foreign currency risks related to monetary assets and liabilities denominated in currencies other than the U.S. dollar. These derivative financial instruments have terms of one month or less and are not designated as hedging instruments. Changes in fair value of these derivatives are recognized in other expense, net, along with the re-measurement gain or loss on the foreign currency denominated assets or liabilities. As of December 29, 2024, we had foreign exchange forward contracts in place to hedge exposures in the euro, Japanese yen, Australian dollar, Canadian dollar, Singapore dollar, Chinese Yuan Renminbi, and British pound.
Warranties
Warranties
We generally provide a one-year warranty on instruments. Additionally, we provide a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, an accrual is established for estimated warranty expenses based on historical experience as well as anticipated product performance. We periodically review the warranty reserve for adequacy and adjust the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.
Share-Based Compensation
Share-Based Compensation
Share-based compensation expense is incurred related to restricted stock, employee stock purchase plan (ESPP), stock options, and, prior to the GRAIL Spin-Off on June 24, 2024, cash-based equity incentive awards. Forfeitures are accounted for, as incurred, as a reversal of share-based compensation expense related to awards that will not vest.
Restricted stock units (RSU) and performance stock units (PSU) are both considered restricted stock. The determination of the amount of share-based compensation expense for our PSU requires the use of certain estimates and assumptions that affect the amount of share-based compensation expense recognized in our consolidated statements of operations. The fair value of restricted stock and performance stock units that do not include a market condition is determined by the closing market price of our common stock on the date of grant. PSU that do not include a market condition represent a right to receive a certain number of shares of common stock based on the achievement of corporate performance goals and continued employment during the vesting period. At each reporting period, we reassess the probability of the achievement of such corporate performance goals and any increase or decrease in share-based compensation expense resulting from an adjustment in the estimated shares to be released is treated as a cumulative catch-up in the period of adjustment. The fair value of performance stock units that include a market condition is determined on the date of grant using a Monte Carlo simulation, which includes assumptions for expected volatility, risk-free interest rate and dividend yield. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Share-based compensation expense is recognized based on the fair value on a straight-line basis over the requisite service periods of the awards. Compensation expense for PSU that include a market condition is recognized over the requisite service period regardless of whether the market conditions are achieved.
The Black-Scholes-Merton option-pricing model is used to estimate the fair value of stock purchased under our ESPP and stock options granted. The model assumptions include expected volatility, term, dividends, and the risk-free interest rate. The expected volatility is generally determined by weighing the historical and implied volatility of our common stock. The historical volatility is generally commensurate with the estimated expected term. The implied volatility is calculated from the implied market volatility of exchange-traded call options on our common stock. The expected term is generally based on historical forfeiture experience, exercise activity, and on the terms and conditions of the stock awards. The expected dividend yield is determined to be 0% given that we have never declared or paid cash dividends on our common stock and do not anticipate paying such cash dividends. The risk-free interest rate is based upon U.S. Treasury securities with remaining terms similar to the expected term of the share-based awards.
Cash-based equity incentive awards were classified as liability awards, as such awards were to be settled in cash. In connection with the Spin-Off of GRAIL, these awards were assumed by GRAIL. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, was used. The fair value of the awards was recorded over the respective vesting periods of the awards, with recognition of a corresponding liability recorded in accrued liabilities in the consolidated balance sheets. The awards were remeasured to fair value at each reporting date until the awards were settled, with changes in fair value recognized in share-based compensation expense.
Research and Development
Research and Development
Research and development expenses include personnel expenses, contractor fees, facilities-related costs, material costs, and license fees. Expenditures relating to research and development are expensed in the period incurred.
Advertising Costs
Advertising Costs
Advertising costs are expensed as incurred
Restructuring
Restructuring
We measure and accrue liabilities associated with employee separation costs, which primarily consist of severance pay and other separation costs such as outplacement services and benefits, at fair value as of the date the plan is approved and when such costs are reasonably estimable. The fair value measurement of restructuring related liabilities requires certain assumptions and estimates to be made, such as the retention period of certain employees. It is our policy to use the best estimates based on facts and circumstances available at the time of measurement, review the assumptions and estimates periodically, and adjust the liabilities when necessary.
Income Taxes
Income Taxes
The provision for income taxes is computed using the asset and liability method, under which deferred tax assets and liabilities are recognized for the expected future tax consequences of temporary differences between the financial reporting and tax bases of assets and liabilities, and for the expected future tax benefit to be derived from tax loss and credit carryforwards. Deferred tax assets and liabilities are determined using the enacted tax rates in effect for the years in which those tax assets are expected to be realized. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in the provision for income taxes in the period that includes the enactment date.
Deferred tax assets are regularly assessed to determine the likelihood they will be recovered from future taxable income. A valuation allowance is established when we believe it is more likely than not the future realization of all or some of a deferred tax asset will not be achieved. In evaluating the ability to recover deferred tax assets within the jurisdiction which they arise, we consider all available positive and negative evidence. Factors reviewed include the cumulative pre-tax book income for the past three years, scheduled reversals of deferred tax liabilities, history of earnings and reliable forecasting, projections of pre-tax book income over the foreseeable future, and the impact of any feasible and prudent tax planning strategies.
The impact of a tax position is recognized in the consolidated financial statements only if that position is more likely than not of being sustained upon examination by taxing authorities, based on the technical merits of the position. Any interest and penalties related to uncertain tax positions will be reflected in income tax expense.
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES (Tables)
12 Months Ended
Dec. 29, 2024
Accounting Policies [Abstract]  
Schedule of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings Per Share, Earnings Per Share
The weighted average shares used to calculate basic and diluted loss per share were as follows:
 Years Ended
In millionsDecember 29,
2024
December 31,
2023
January 1,
2023
Weighted average shares used in calculating basic loss per share
159 158 157 
Weighted average shares used in calculating diluted loss per share
159 158 157 
Antidilutive shares:
Equity awards4 
Convertible senior notes 
Potentially dilutive shares excluded due to antidilutive effect
4 
Schedule of Estimated Useful Lives of Major Classes of Property and Equipment
The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years
Property and Equipment
In millionsDecember 29,
2024
December 31,
2023
Leasehold improvements$772 $803 
Machinery and equipment683 684 
Computer hardware and software478 463 
Furniture and fixtures53 55 
Buildings44 44 
Construction in progress39 96 
Total property and equipment, gross2,069 2,145 
Accumulated depreciation(1,254)(1,138)
Total property and equipment, net$815 $1,007 
v3.25.0.1
GRAIL SPIN-OFF (Tables)
12 Months Ended
Dec. 29, 2024
Discontinued Operations and Disposal Groups [Abstract]  
Schedule of Assets and Liabilities Included as Part of the Disposal Group
The carrying amounts of GRAIL’s assets and liabilities included as part of the disposal group were as follows:
In millions
Cash and cash equivalents
$968 
Accounts receivable, net
13 
Inventory, net
22 
Prepaid expenses and other current assets
27 
Property and equipment, net
80 
Operating lease right-of-use assets
74 
Intangible assets, net(1)
2,201 
Other assets14 
Accounts payable(12)
Accrued liabilities (118)
Operating lease liabilities(62)
Other long term-liabilities(469)
GRAIL net assets
$2,738 
Amount of GRAIL net assets recorded to short-term investments
$397 
Amount of GRAIL net assets recorded to additional paid-in capital
$2,341 
Additional adjustments recorded to additional paid-in capital as a result of the GRAIL Spin-Off:
Non-contingent indemnification liability (see Note 7)
Tax adjustment for difference between the book and tax values of our retained investment in GRAIL
57 
Total recorded to additional paid-in capital as a result of the GRAIL Spin-Off
$2,399 
_____________
(1)Includes IPR&D with a carrying value of $140 million after impairment. Refer to note 5. Goodwill, Intangible Assets, and Acquisitions.
v3.25.0.1
REVENUE (Tables)
12 Months Ended
Dec. 29, 2024
Revenue from Contract with Customer [Abstract]  
Schedule of Disaggregation of Revenue
Revenue by Source
202420232022
In millionsSequencingMicroarrayTotalSequencingMicroarrayTotalSequencingMicroarrayTotal
Consumables$2,858 $297 $3,155 $2,790 $293 $3,083 $2,919 $306 $3,225 
Instruments484 17 501 685 19 704 709 19 728 
Total product revenue3,342 314 3,656 3,475 312 3,787 3,628 325 3,953 
Service and other revenue651 65 716 637 80 717 543 88 631 
Total revenue$3,993 $379 $4,372 $4,112 $392 $4,504 $4,171 $413 $4,584 
Revenue by Geographic Area
Based on region of destination (in millions)20242023
2022(1)
Americas(2)
$2,441 $2,521 $2,479 
Europe1,185 1,140 1,089 
Greater China(3)
308 384 472 
Asia-Pacific, Middle East and Africa(4)
438 459 544 
Total revenue$4,372 $4,504 $4,584 
_____________
(1)We implemented a new global commercial structure in Q1 2023 to improve operating efficiencies and better align with local markets. We integrated Asia-Pacific and Japan with emerging markets across the Middle East, Africa, Turkey, and Commonwealth of Independent States (CIS). Beginning in Q1 2023, and going forward, we report regional results for the following regions: Americas, Europe, Greater China, and Asia-Pacific, Middle East and Africa (AMEA). Prior period amounts have been reclassified to conform to this new presentation.
(2)Americas revenue included United States revenue of $2,288 million, $2,359 million, and $2,290 million in 2024, 2023 and 2022, respectively.
(3)Region includes revenue from China, Taiwan, and Hong Kong.
(4)Region includes revenue from Russia and Turkey.
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS (Tables)
12 Months Ended
Dec. 29, 2024
Fair Value Disclosures [Abstract]  
Schedule of Marketable Securities
Gains and (losses) recognized in other expense, net on marketable equity securities were as follows:
In millions202420232022
Net (losses) recognized during the period on marketable equity securities
$(310)$(2)$(81)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period
 (2)— 
Net unrealized (losses) recognized during the period on marketable equity securities still held at the reporting date
$(310)$— $(81)
Schedule of Other Commitments
Our commitments to the Funds are as follows:
Dollars in millions
Capital commitments
Callable through date
Remaining callable as of December 29, 2024(1)
Fund I
$100 April 2026$
Fund II
$150 July 2029$46 
Fund III
$60 December 2034$47 
_____________
(1)Fund I also had recallable distributions of approximately $10 million.
Schedule of Fair Value Hierarchy for Assets and Liabilities Measured at Fair Value on a Recurring Basis
The following table presents the hierarchy for assets and liabilities measured at fair value on a recurring basis:
December 29, 2024December 31, 2023
In millionsLevel 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets:
Money market funds (cash equivalents)$931 $ $ $931 $774 $— $— $774 
Marketable equity securities93   93 — — 
Other investments
  17 17 — — — — 
Helix contingent value right    — — 68 68 
Deferred compensation plan assets 70  70 — 61 — 61 
Total assets measured at fair value$1,024 $70 $17 $1,111 $780 $61 $68 $909 
Liabilities:
Contingent consideration liabilities$ $ $73 $73 $— $— $387 $387 
Deferred compensation plan liability 65  65 — 59 — 59 
Total liabilities measured at fair value$ $65 $73 $138 $— $59 $387 $446 
Schedule of Changes in Estimated Fair Value of Acquisition Related Contingent Consideration Liabilities
Changes in the Helix contingent value right were as follows:
In millions
Balance as of January 2, 2022$65 
Change in estimated fair value(7)
Balance as of January 1, 202358 
Change in estimated fair value10 
Balance as of December 31, 202368 
Change in estimated fair value15 
Cash received to settle(83)
Balance as of December 29, 2024$ 
Changes in the estimated fair value of our contingent consideration liabilities were as follows:
In millions
Balance as of January 2, 2022$615 
Acquisition
Change in estimated fair value(205)
Balance as of January 1, 2023412 
Change in estimated fair value(24)
Cash payments(1)
Balance as of December 31, 2023387 
Acquisition2 
Change in estimated fair value(315)
Cash payments(1)
Balance as of December 29, 2024$73 
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS (Tables)
12 Months Ended
Dec. 29, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of Goodwill Goodwill
In millions
Balance as of January 1, 2023(1)
$3,239 
Impairment(712)
Acquisition18 
Balance as of December 31, 20232,545 
Impairment(1,466)
Acquisition34 
Balance as of December 29, 2024$1,113 
_____________
(1) The balance as of January 1, 2023 includes accumulated impairment of $3,914 million related to our GRAIL reporting unit.
Schedule of Finite-lived Intangible Assets
Intangible Assets
 December 29, 2024December 31, 2023
In millionsGross
Carrying
Amount
Accumulated
Amortization
Intangible Assets,
Net
Gross
Carrying
Amount
Accumulated
Amortization
ImpairmentIntangible Assets,
Net
Developed technologies$465 $(305)$160 $2,807 $(585)$— $2,222 
Licensed technologies234 (114)120 274 (133)— 141 
License agreements19 (13)6 14 (13)— 
Customer relationships16 (14)2 14 (13)— 
Database12 (5)7 12 (3)— 
Trade name2 (2) 43 (14)— 29 
Total finite-lived intangible assets, net748 (453)295 3,164 (761)— 2,403 
In-process research and development (IPR&D)   705 — (115)590 
Total intangible assets, net$748 $(453)$295 $3,869 $(761)$(115)$2,993 
Schedule of Estimated Annual Amortization of Finite-lived Intangible Assets
The estimated future annual amortization of finite-lived intangible assets is shown in the following table. Actual amortization expense to be reported in future periods could differ from these estimates as a result of acquisitions, divestitures, and asset impairments, among other factors.
In millionsEstimated Annual Amortization
2025$69 
202657 
202755 
202852 
202923 
Thereafter39 
Total$295 
v3.25.0.1
DEBT AND OTHER COMMITMENTS (Tables)
12 Months Ended
Dec. 29, 2024
Debt Disclosure [Abstract]  
Schedule of Debt Obligations Summary of Term Debt Obligations
In millionsDecember 29,
2024
December 31,
2023
Principal amount of 2025 Term Notes outstanding$500 $500 
Principal amount of 2026 Term Notes outstanding500 — 
Principal amount of 2027 Term Notes outstanding500 500 
Principal amount of 2031 Term Notes outstanding500 500 
Unamortized discounts and debt issuance costs(11)(11)
Net carrying amount of term debt
1,989 1,489 
Less: current portion499 — 
Term debt, non-current
$1,490 $1,489 
Fair value of term debt outstanding (Level 2)
$1,940 $1,440 
Schedule of Leases
As of December 29, 2024, the maturities of our operating lease liabilities were as follows:
In millions
2025$105
2026105
2027103
202884
202981
Thereafter275
Total remaining lease payments
753
Less: imputed interest(120)
Total operating lease liabilities633
Less: current portion(79)
Long-term operating lease liabilities$554
Weighted-average remaining lease term8.0 years
Weighted-average discount rate4.4 %
Schedule of Components of Lease Costs
The components of our lease costs were as follows:
In millions202420232022
Operating lease costs
$93 $116 $112 
Sublease income(19)(20)(20)
Variable lease costs(1)
25 27 20 
Total lease costs$99 $123 $112 
_____________
(1)Variable lease costs include non-fixed maintenance charges and property taxes.
v3.25.0.1
STOCKHOLDERS' EQUITY (Tables)
12 Months Ended
Dec. 29, 2024
Equity [Abstract]  
Schedule of Restricted Stock Activity and Related Information, Restricted Stock
Restricted stock activity was as follows:
Restricted
Stock Units
(RSU)
Performance
Stock Units
(PSU) (1)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987)— $268.08 $— 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
Awarded2,788 729 $133.73 $164.38 
Unvested adjustment for GRAIL Spin-Off
107 12 $ $ 
Vested(771) $249.70 $ 
Cancelled(443)(41)$195.11 $167.68 
Outstanding at December 29, 20243,879 700 $158.60 $164.87 
_____________
(1)For EPS and OM PSU, the number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. Awarded units are presented net of performance adjustments.
Schedule of Restricted Stock Activity and Related Information, Performance Units
Restricted stock activity was as follows:
Restricted
Stock Units
(RSU)
Performance
Stock Units
(PSU) (1)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987)— $268.08 $— 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
Awarded2,788 729 $133.73 $164.38 
Unvested adjustment for GRAIL Spin-Off
107 12 $ $ 
Vested(771) $249.70 $ 
Cancelled(443)(41)$195.11 $167.68 
Outstanding at December 29, 20243,879 700 $158.60 $164.87 
_____________
(1)For EPS and OM PSU, the number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. Awarded units are presented net of performance adjustments.
Schedule of Pre-tax Intrinsic Values of Vested Restricted Stock
Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202420232022
Pre-tax intrinsic value of outstanding restricted stock:
RSU$525 $306 $326 
PSU$95 $— $15 
Fair value of restricted stock vested:
RSU$116 $122 $162 
PSU$ $— $49 
Schedule of Total Fair Value of Vested Restricted Stock
Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202420232022
Pre-tax intrinsic value of outstanding restricted stock:
RSU$525 $306 $326 
PSU$95 $— $15 
Fair value of restricted stock vested:
RSU$116 $122 $162 
PSU$ $— $49 
Schedule of Stock Option Activity Under all Stock Option Plans
Stock option activity was as follows:
Units in thousandsOptionsWeighted-Average
Exercise Price
Performance Stock Options(1)
Weighted-Average
Exercise Price
Outstanding at January 2, 2022$66.42 17 $85.54 
Granted180 $330.25 — $— 
Exercised(1)$6.55 — $— 
Outstanding at January 1, 2023187 $319.72 17 $85.54 
Exercised(8)$71.09 (1)$16.69 
Cancelled(144)$330.25 — $— 
Outstanding at December 31, 202335 $330.25 16 $87.74 
Cancelled(35)$330.25 (16)$87.74 
Outstanding at December 29, 2024 $  $ 
_____________
(1)In connection with the GRAIL acquisition, we issued replacement performance stock options to GRAIL employees in 2021. The number of units reflected awards that had been granted and for which it was assumed to be probable that the underlying performance goals would be achieved. In connection with the GRAIL Spin-Off, all outstanding performance stock options were assumed by GRAIL.
Schedule of Cash-Based Equity Incentive Award Activity
Cash-based equity incentive award activity was as follows:
In millions
Outstanding at January 2, 2022$184 
Granted168 
Vested and paid in cash
(41)
Cancelled(41)
Change in fair value23 
Outstanding at January 1, 2023293 
Granted116 
Vested and paid in cash
(77)
Cancelled(32)
Change in fair value(8)
Outstanding at December 31, 2023292 
Granted67 
Vested and paid in cash(54)
Cancelled(13)
Change in fair value(9)
Derecognition for GRAIL Spin-Off(1)
(283)
Outstanding at December 29, 2024$ 
_____________
(1)The estimated liability immediately prior to the Spin-Off, recorded in accrued liabilities, was $53 million, which was disposed of as part of GRAIL’s net assets. See note 2. GRAIL Spin-Off for additional details.
Schedule of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan
The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the ESPP were as follows:
202420232022
Risk-free interest rate
4.35% - 5.54%
 0.78% - 5.54%
0.06% - 2.98%
Expected volatility
41% - 49%
 41% - 51%
37% - 51%
Expected term
0.5 - 1.1 year
 0.5 - 1.1 year
0.5 - 1.0 year
Expected dividends0%0%0%
Weighted-average grant-date fair value per share$37.24 $49.87 $50.22 
Schedule of Share repurchase activity
Share repurchase activity during 2024 was as follows:
In millions, except shares in thousands
Number of shares repurchased
904 
Total cost of shares repurchased(1)
$116 
_____________
(1)Total cost of shares repurchased includes the 1% excise tax imposed as part of the Inflation Reduction Act of 2022, which is calculated based on share repurchases, net of certain share issuances.
Schedule of Share-Based Compensation Expense for all Stock Awards
Share-based compensation expense, which includes expense for both equity and liability-classified awards, reported in our consolidated statements of operations was as follows:
In millions202420232022
Cost of product revenue$25 $29 $26 
Cost of service and other revenue6 
Research and development146 155 153 
Selling, general and administrative194 189 181 
Share-based compensation expense, before taxes371 380 366 
Related income tax benefits(83)(87)(83)
Share-based compensation expense, net of taxes$288 $293 $283 
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS (Tables)
12 Months Ended
Dec. 29, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Accounts Receivable Accounts Receivable
In millionsDecember 29,
2024
December 31,
2023
Trade accounts receivable, gross$744 $741 
Allowance for credit losses(9)(7)
Total accounts receivable, net$735 $734 
Schedule of Inventory
Inventory
In millionsDecember 29,
2024
December 31,
2023
Raw materials$225 $276 
Work in process404 402 
Finished goods31 30 
Inventory, gross660 708 
Inventory reserve(113)(121)
Total inventory, net$547 $587 
Schedule of Property and Equipment
The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years
Property and Equipment
In millionsDecember 29,
2024
December 31,
2023
Leasehold improvements$772 $803 
Machinery and equipment683 684 
Computer hardware and software478 463 
Furniture and fixtures53 55 
Buildings44 44 
Construction in progress39 96 
Total property and equipment, gross2,069 2,145 
Accumulated depreciation(1,254)(1,138)
Total property and equipment, net$815 $1,007 
Schedule of Accrued Liabilities
Accrued Liabilities
In millionsDecember 29,
2024
December 31,
2023
Legal contingencies(1)
$26 $484 
Contract liabilities, current portion260 252 
Accrued compensation expenses
252 223 
Accrued taxes payable101 79 
Operating lease liabilities, current portion79 86 
Liability-classified equity incentive awards 55 
Other, including warranties(2)
109 146 
Total accrued liabilities$827 $1,325 
_____________
(1)See note 9. Legal Proceedings for additional details.
(2)See table below for changes in the reserve for product warranties.
Schedule of Changes in Reserve for Product Warranties
Changes in the reserve for product warranties were as follows:
In millions
Balance as of January 2, 2022$22 
Additions charged to cost of product revenue23 
Repairs and replacements(27)
Balance as of January 1, 202318 
Additions charged to cost of product revenue42 
Repairs and replacements(39)
Balance as of December 31, 202321 
Additions charged to cost of product revenue42 
Repairs and replacements(45)
Balance as of December 29, 2024$18 
Schedule of Restructuring and Related Costs
A summary of the pre-tax restructuring charges is as follows:
In millions20242023Cumulative charges recorded since inception
Employee separation costs$12 $48 $60 
Asset impairment charges(1)
46 100 146 
Other costs
Total restructuring charges(2)
$62 $152 $214 
_____________
(1)For 2024, relates to impairment of right-of-use assets and leasehold improvements for Foster City campus and other property in San Diego.
For 2023, primarily relates to impairment of right-of-use assets and leasehold improvements for our i3 and Foster City campuses.
(2)For 2024, $59 million was recorded in SG&A expense, $2 million in R&D expense, and remainder in cost of revenue.
For 2023, $122 million was recorded in SG&A expense, $24 million in R&D expense, and remainder in cost of revenue.
Total restructuring charges primarily relate to our Core Illumina segment.
A summary of the restructuring liability is as follows:
In millions
Employee Separation Costs
Other CostsTotal
Amount recorded in accrued liabilities as of January 1, 2023
$— $— $— 
Expense recorded
48 52 
Cash payments(31)(3)(34)
Amount recorded in accrued liabilities as of December 31, 2023
17 1 18 
Expense recorded
12 4 16 
Cash payments(24)(2)(26)
Adjustments to accrual(3)(1)(4)
Amount recorded in accrued liabilities as of December 29, 2024
$2 $2 $4 
v3.25.0.1
INCOME TAXES (Tables)
12 Months Ended
Dec. 29, 2024
Income Tax Disclosure [Abstract]  
Schedule of (Loss) Income before Income Taxes by Region
Loss before income taxes summarized by region was as follows:
In millions202420232022
United States$(1,834)$(1,735)$(4,942)
Foreign655 618 606 
Total loss before income taxes
$(1,179)$(1,117)$(4,336)
Schedule of Provision for Income Taxes
The provision for income taxes consisted of the following:
In millions202420232022
Current:   
Federal$6 $(5)$(11)
State18 27 
Foreign137 77 75 
Total current provision161 78 91 
Deferred:
Federal(59)(13)40 
State(56)(26)(47)
Foreign(2)(16)
Total deferred benefit(117)(34)(23)
Total tax provision$44 $44 $68 
Schedule of Reconciliation of Provision for (Loss) Income Taxes to Amount Computed by Applying the Federal Statutory Rate
The provision for income taxes reconciles to the amount computed by applying the federal statutory rate to loss before income taxes as follows:
In millions202420232022
Tax at federal statutory rate$(248)$(235)$(911)
State, net of federal benefit(38)(16)(9)
Research and other credits(32)(42)(46)
Change in valuation allowance29 48 62 
Impact of R&D expense capitalization52 86 87 
Impact of net operating losses on GILTI, U.S. foreign tax credits, and Pillar Two global minimum top-up tax
90 61 60 
Impact of foreign operations3 (50)(81)
Stock compensation16 31 20 
Accrual of European Commission fine(99)96 
Goodwill impairment308 149 822 
Impact of acquisition related items(46)(27)
Other9 (5)
Total tax provision$44 $44 $68 
Schedule of Significant Components of Deferred Tax Assets and Liabilities
Significant components of deferred tax assets and liabilities were as follows:
In millionsDecember 29,
2024
December 31,
2023
Deferred tax assets:  
Net operating losses$189 $392 
Tax credits252 211 
Other accruals and reserves40 49 
Stock compensation34 15 
Capitalized U.S. R&D expenses181 158 
Other amortization42 115 
Operating lease liabilities112 146 
Property and equipment17 
Investments23 
Other63 56 
Total gross deferred tax assets953 1,153 
Valuation allowance on deferred tax assets(278)(251)
Total deferred tax assets
675 902 
Deferred tax liabilities:  
Purchased intangible amortization(35)(734)
Operating lease right-of-use assets(57)(88)
Other(25)(25)
Total deferred tax liabilities(117)(847)
Deferred tax assets, net$558 $55 
Schedule of Unrecognized Tax Benefits Roll Forward
The following table summarizes the gross amount of our uncertain tax positions:
In millionsDecember 29,
2024
December 31,
2023
January 1,
2023
Balance at beginning of year$210 $153 $131 
Increases related to prior year tax positions2 27 12 
Decreases related to prior year tax positions(2)(2)(3)
Increases related to current year tax positions23 42 42 
Decreases related to lapse of statute of limitations(1)(10)(29)
Balance at end of year$232 $210 $153 
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION (Tables)
12 Months Ended
Dec. 29, 2024
Segment Reporting [Abstract]  
Schedule of Operating Performance and Assets by Segment
Our CODM allocates resources and evaluates business performance based on revenues and net income (loss). Net income (loss) is used in the annual budgeting and monthly forecasting processes and to monitor and assess budgeted/forecasted versus actual results. Our CODM does not evaluate segments using asset information. The accounting policies for segments are the same as those described in the summary of significant accounting policies.
The following tables present selected financial information with respect to segments for the periods presented:
In millions202420232022
Core Illumina:
Revenue(1)
$4,332 $4,438 $4,553 
Less:
Cost of revenue1,424 1,582 1,446 
Research and development988 1,030 1,004 
Selling and marketing638 648 677 
General and administrative262 600 326 
Goodwill and intangible impairment
3 — 
Legal contingency and settlement
(456)20 619 
Core Illumina income from operations1,473 552 481 
GRAIL:
Revenue
55 93 55 
Total operating expenses(2)
2,360 1,714 4,712 
Consolidated other expense, net
346 48 157 
Consolidated provision for income taxes
44 44 68 
Intersegment eliminations
(1)— (3)
Consolidated net loss$(1,223)$(1,161)$(4,404)
_____________
(1)Core Illumina revenue for 2024, 2023, and 2022 included intercompany revenue of $15 million, $26 million, and $24 million, respectively.
(2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative periods prior to the Spin-Off on June 24, 2024.
 In millions202420232022
Depreciation and amortization:
Core Illumina$280 $273 $240 
GRAIL74 159 154 
Consolidated depreciation and amortization$354 $432 $394 
Capital expenditures:
Core Illumina$137 $183 $262 
GRAIL5 13 24 
Eliminations (1)— 
Consolidated capital expenditures$142 $195 $286 
Schedule of Net Long-lived Assets Consisting of Property and Equipment by Region
Long-lived assets, consisting of property and equipment and operating lease right-of-use assets, were as follows:
In millionsDecember 29,
2024
December 31,
2023
United States$750 $1,040 
Singapore279 298 
United Kingdom124 136 
Other countries81 77 
Total long-lived assets, net
$1,234 $1,551 
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Business Overview (Details) - Spinoff - GRAIL
Jun. 24, 2024
shares
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]  
Number of shares issued in transaction 26,547,021
Percent of interest disposed 85.50%
Discontinued operation, equity method investment retained after disposal, ownership interest after disposal 14.50%
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Concentrations of Risk (Details)
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Credit Concentration Risk | Investment Portfolio      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 5.00%    
Credit Concentration Risk | Issue Size      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 5.00%    
Industry Credit Concentration Risk | Investment Portfolio      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 30.00%    
United States | Customer Concentration Risk | Revenue Benchmark      
Concentration Risk [Line Items]      
Concentration percent 48.00% 48.00% 50.00%
Outside the United States | Geographic Concentration Risk | Accounts Receivable      
Concentration Risk [Line Items]      
Concentration percent 53.00% 55.00%  
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Recently Adopted Accounting Policies (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Jan. 03, 2022
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Retained earnings (accumulated deficit) $ (1,242) $ (19)  
Additional paid-in capital $ (7,525) $ (9,555)  
ASU 2020-06 | Cumulative Effect, Period of Adoption, Adjustment      
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Retained earnings (accumulated deficit)     $ 61
Additional paid-in capital     $ (93)
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Revenue Recognition (Details)
12 Months Ended
Dec. 29, 2024
Product  
Revenue from External Customer [Line Items]  
Payment period from invoice 30 days
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Schedule of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings (Loss) Per Share (Details) - shares
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Accounting Policies [Abstract]      
Weighted average shares outstanding (in shares) 159,000,000 158,000,000 157,000,000
Weighted average shares used in calculating diluted earnings (loss) per share (in shares) 159,000,000 158,000,000 157,000,000
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded due to antidilutive effect 4,000,000 4,000,000 4,000,000
Equity awards      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded due to antidilutive effect 4,000,000 3,000,000 2,000,000
Convertible senior notes      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded due to antidilutive effect 0 1,000,000 2,000,000
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Schedule of Estimated Useful Lives of Major Classes of Property and Equipment (Details)
Dec. 29, 2024
Buildings and leasehold improvements | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 4 years
Buildings and leasehold improvements | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 20 years
Machinery and equipment | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 3 years
Machinery and equipment | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 5 years
Computer hardware and software | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 3 years
Computer hardware and software | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 9 years
Furniture and fixtures  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 7 years
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Leases (Details)
Dec. 29, 2024
Minimum  
Property, Plant and Equipment [Line Items]  
Lessee, operating lease, remaining lease term 1 year
Lessee, operating lease, renewal term 2 years
Maximum  
Property, Plant and Equipment [Line Items]  
Lessee, operating lease, remaining lease term 14 years
Lessee, operating lease, renewal term 20 years
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Derivative Financial Instruments (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Sep. 29, 2024
Derivative Instruments, Gain (Loss) [Line Items]        
Derivative term 24 months      
Other comprehensive income (loss) hedge $ 15 $ 18 $ 53  
Gain to be reclassified into earnings within the next 12 months 27      
GRAIL        
Derivative Instruments, Gain (Loss) [Line Items]        
Loss contingency accrual       $ 432
Foreign Exchange Forward        
Derivative Instruments, Gain (Loss) [Line Items]        
Derivative assets related to terminated acquisition 27 5    
Derivative liabilities related to terminated acquisition   9    
Foreign Exchange Forward | Not Designated as Hedging Instrument        
Derivative Instruments, Gain (Loss) [Line Items]        
Notional amount of outstanding forward contracts 477 926    
Foreign Exchange Forward | Designated as Hedging Instrument        
Derivative Instruments, Gain (Loss) [Line Items]        
Notional amount of outstanding forward contracts $ 621 $ 628    
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Warranties (Details)
12 Months Ended
Dec. 29, 2024
Instruments  
Product Warranty Liability [Line Items]  
Warranty period 1 year
Consumables | Minimum  
Product Warranty Liability [Line Items]  
Warranty period 6 months
Consumables | Maximum  
Product Warranty Liability [Line Items]  
Warranty period 12 months
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Share-Based Compensation (Details)
12 Months Ended
Dec. 29, 2024
Accounting Policies [Abstract]  
Expected dividend yield 0.00%
v3.25.0.1
ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES - Narrative - Advertising Costs (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Accounting Policies [Abstract]      
Advertising costs $ 37 $ 36 $ 53
v3.25.0.1
GRAIL SPIN-OFF - Narrative (Details) - Spinoff - GRAIL - USD ($)
$ in Millions
12 Months Ended
Jun. 24, 2024
Dec. 29, 2024
Dec. 31, 2023
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Number of shares issued in transaction 26,547,021    
Percent of interest disposed 85.50%    
Number of parent shares converted into one share of spin-off (in shares) 6    
Discontinued operation, equity method investment retained after disposal, ownership interest after disposal 14.50%    
Period of continuing involvement after disposal 2 years 6 months 2 years 6 months  
Amount of continuing cash flows after disposal $ 974    
Separation-related transaction costs   $ 53 $ 17
v3.25.0.1
GRAIL SPIN-OFF - Assets and Liabilities Included as Part of the Disposal Group (Details) - USD ($)
$ in Millions
Jun. 24, 2024
Dec. 29, 2024
Jan. 01, 2023
GRAIL Inc      
Additional adjustments recorded to additional paid-in capital as a result of the GRAIL Spin-Off:      
Accumulated impairment loss     $ 3,914
GRAIL | Spinoff      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Cash and cash equivalents $ 968    
Accounts receivable, net 13    
Inventory, net 22    
Prepaid expenses and other current assets 27    
Property and equipment, net 80    
Operating lease right-of-use assets 74    
Intangible assets, net 2,201    
Other assets 14    
Accounts payable (12)    
Accrued liabilities (118)    
Operating lease liabilities (62)    
Other long term-liabilities (469)    
GRAIL net assets 2,738    
Additional adjustments recorded to additional paid-in capital as a result of the GRAIL Spin-Off:      
Non-contingent indemnification liability (see Note 7)   $ 1  
Tax adjustment for difference between the book and tax values of our retained investment in GRAIL 57    
Total recorded to additional paid-in capital as a result of the GRAIL Spin-Off 2,399    
GRAIL | Spinoff | In-process research and development (IPR&D)      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Intangible assets, net 140    
GRAIL | Spinoff | Short-Term Investments      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
GRAIL net assets 397    
GRAIL | Spinoff | Additional Paid-In Capital      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
GRAIL net assets $ 2,341    
v3.25.0.1
REVENUE - Schedule of Disaggregation of Revenue (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Revenue from External Customer [Line Items]      
Revenue $ 4,372 $ 4,504 $ 4,584
Americas      
Revenue from External Customer [Line Items]      
Revenue 2,441 2,521 2,479
Europe      
Revenue from External Customer [Line Items]      
Revenue 1,185 1,140 1,089
Greater China      
Revenue from External Customer [Line Items]      
Revenue 308 384 472
Asia-Pacific, Middle East and Africa      
Revenue from External Customer [Line Items]      
Revenue 438 459 544
United States      
Revenue from External Customer [Line Items]      
Revenue 2,288 2,359 2,290
Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 3,656 3,787 3,953
Consumables      
Revenue from External Customer [Line Items]      
Revenue 3,155 3,083 3,225
Instruments      
Revenue from External Customer [Line Items]      
Revenue 501 704 728
Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue 716 717 631
Sequencing      
Revenue from External Customer [Line Items]      
Revenue 3,993 4,112 4,171
Sequencing | Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 3,342 3,475 3,628
Sequencing | Consumables      
Revenue from External Customer [Line Items]      
Revenue 2,858 2,790 2,919
Sequencing | Instruments      
Revenue from External Customer [Line Items]      
Revenue 484 685 709
Sequencing | Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue 651 637 543
Microarray      
Revenue from External Customer [Line Items]      
Revenue 379 392 413
Microarray | Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 314 312 325
Microarray | Consumables      
Revenue from External Customer [Line Items]      
Revenue 297 293 306
Microarray | Instruments      
Revenue from External Customer [Line Items]      
Revenue 17 19 19
Microarray | Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue $ 65 $ 80 $ 88
v3.25.0.1
REVENUE - Narrative - Remaining Performance Obligation (Details)
$ in Millions
12 Months Ended
Dec. 29, 2024
USD ($)
Revenue from Contract with Customer [Abstract]  
Remaining performance obligation $ 657
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Remaining performance obligation $ 657
Minimum  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Product or service delivery period 3 months
Maximum  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Product or service delivery period 6 months
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2025-01-01  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Percent of remaining performance obligation 78.00%
Revenue, remaining performance obligation, expected timing of satisfaction, period 1 year
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2026-01-01  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Percent of remaining performance obligation 10.00%
Revenue, remaining performance obligation, expected timing of satisfaction, period 12 months
v3.25.0.1
REVENUE - Narrative - Contract Assets and Liabilities (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 29, 2024
Revenue from Contract with Customer [Abstract]    
Contract asset $ 18 $ 16
Contract liability 329 327
Contract liabilities, current portion 252 $ 260
Revenue recognized, previously deferred $ 245  
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS - Narrative (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Jun. 24, 2024
USD ($)
Apr. 30, 2019
Dec. 29, 2024
USD ($)
day
fund
Sep. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Oct. 01, 2023
USD ($)
Jan. 01, 2023
USD ($)
Oct. 02, 2022
USD ($)
Schedule of Investments [Line Items]                
Short-term Investments     $ 93,000   $ 6,000      
Discontinued Operation Gain Loss On Disposal Statement Of Income Or Comprehensive Income Extensible Enumeration Not Disclosed Flag     unrealized loss          
Strategic equity investments, without readily determinable fair values     $ 26,000   28,000      
Revenue     $ 4,372,000   4,504,000   $ 4,584,000  
GRAIL                
Schedule of Investments [Line Items]                
Contingent value right, terms     12 years          
Covered revenues of GRAIL, contingent consideration liability       $ 117,000   $ 85,000   $ 42,000
Payment for contingent consideration     $ 1,100   803   396  
GRAIL | Payment Rights Of One Billion Each Twelve Years                
Schedule of Investments [Line Items]                
Contingent payment rights, first percentage     2.50%          
Business acquisition, contingent value rights, revenue threshold     $ 1,000,000          
GRAIL | Payment Rights Of Above One Billion Each Twelve Years                
Schedule of Investments [Line Items]                
Business acquisition, contingent value rights, revenue threshold     $ 1,000,000          
Contingent payment rights, second percentage     9.00%          
Helix Contingent Consideration                
Schedule of Investments [Line Items]                
Contingent consideration asset settlement     $ 83,000          
Helix Holdings I, LLC                
Schedule of Investments [Line Items]                
Contingent value right, terms   7 years            
Investee                
Schedule of Investments [Line Items]                
Revenue     $ 20,000   69,000   113,000  
Venture Capital Investment Fund (the Fund)                
Schedule of Investments [Line Items]                
Number of venture capital investment funds | fund     3          
Equity method investments     $ 201,000   168,000      
Unrealized gain (loss) on equity method investments     $ 5,000   (33,000)   $ (25,000)  
GRAIL | Revenue Risk Premium                
Schedule of Investments [Line Items]                
Revenue risk premium     0.09          
GRAIL | Measurement Input, Calculation Trailing Period                
Schedule of Investments [Line Items]                
Revenue risk premium | day     60          
Spinoff | GRAIL                
Schedule of Investments [Line Items]                
GRAIL net assets $ 2,738,000              
Discontinued operation, equity method investment retained after disposal, ownership interest after disposal 14.50%              
Loss on disposal of discontinued operation, net of tax     $ 309,000          
Contingent consideration liabilities     71,000   387,000      
Contingent consideration, noncurrent     70,000   $ 385,000      
Increase in 20% of revenue, increase in liability     17,000          
Decrease in 20% of revenue, decrease in liability     (18,000)          
Effect of change of additional 250 basis points, decrease in liability     (12,000)          
Effect of change of additional 250 basis points, increase in liability     $ 15,000          
Short-Term Investments | Spinoff | GRAIL                
Schedule of Investments [Line Items]                
GRAIL net assets $ 397,000              
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS - Schedule of Marketable Equity Securities (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Marketable Securities, Gain (Loss) [Abstract]      
Net (losses) recognized during the period on marketable equity securities $ (310) $ (2) $ (81)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period 0 (2) 0
Net unrealized (losses) recognized during the period on marketable equity securities still held at the reporting date $ (310) $ 0 $ (81)
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS - Other Commitments (Details)
$ in Millions
Dec. 29, 2024
USD ($)
Schedule of Investments [Line Items]  
Recallable distributions $ 10
Fund I  
Schedule of Investments [Line Items]  
Capital commitments 100
Remaining callable 3
Fund II  
Schedule of Investments [Line Items]  
Capital commitments 150
Remaining callable 46
Fund III  
Schedule of Investments [Line Items]  
Capital commitments 60
Remaining callable $ 47
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS - Schedule of Hierarchy for Assets and Liabilities Measured at Fair Value Recurring Basis (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Assets:    
Deferred compensation plan assets $ 70 $ 61
Fair value, Measurements, Recurring    
Assets:    
Money market funds (cash equivalents) 931 774
Marketable equity securities 93 6
Other investments 17 0
Helix contingent value right   68
Deferred compensation plan assets 70 61
Total assets measured at fair value 1,111 909
Liabilities:    
Contingent consideration liabilities 73 387
Deferred compensation plan liability 65 59
Total liabilities measured at fair value 138 446
Fair value, Measurements, Recurring | Level 1    
Assets:    
Money market funds (cash equivalents) 931 774
Marketable equity securities 93 6
Other investments 0 0
Helix contingent value right 0 0
Deferred compensation plan assets 0 0
Total assets measured at fair value 1,024 780
Liabilities:    
Contingent consideration liabilities 0 0
Deferred compensation plan liability 0 0
Total liabilities measured at fair value 0 0
Fair value, Measurements, Recurring | Level 2    
Assets:    
Money market funds (cash equivalents) 0 0
Marketable equity securities 0 0
Other investments 0 0
Helix contingent value right 0 0
Deferred compensation plan assets 70 61
Total assets measured at fair value 70 61
Liabilities:    
Contingent consideration liabilities 0 0
Deferred compensation plan liability 65 59
Total liabilities measured at fair value 65 59
Fair value, Measurements, Recurring | Level 3    
Assets:    
Money market funds (cash equivalents) 0 0
Marketable equity securities 0 0
Other investments 17 0
Helix contingent value right 0 68
Deferred compensation plan assets 0 0
Total assets measured at fair value 17 68
Liabilities:    
Contingent consideration liabilities 73 387
Deferred compensation plan liability 0 0
Total liabilities measured at fair value $ 73 $ 387
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS - Changes in Estimated Fair Value of Acquisition (Details) - Helix Contingent Consideration - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]      
Beginning Balance $ 68 $ 58 $ 65
Change in estimated fair value 15 10 (7)
Cash received to settle (83)    
Ending Balance $ 0 $ 68 $ 58
v3.25.0.1
INVESTMENTS AND FAIR VALUE MEASUREMENTS- Contingent Consideration Liabilities (Details) - Business Combination, Contingent Consideration, Liability - GRAIL - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 02, 2022
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]      
Beginning Balance $ 387 $ 412  
Acquisition 2   $ 2
Change in estimated fair value (315) (24) (205)
Cash payments (1) (1)  
Ending Balance $ 73 $ 387 $ 615
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS - Schedule of Changes in Goodwill (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Goodwill [Roll Forward]      
Balance at beginning of period $ 2,545 $ 3,239  
Impairment (1,466) (712)  
Acquisition 34 18  
Balance at end of period $ 1,113 $ 2,545  
GRAIL Inc      
Goodwill [Roll Forward]      
Accumulated impairment loss     $ 3,914
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS - Narrative (Details)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
May 31, 2024
USD ($)
reporting_unit
Dec. 29, 2024
USD ($)
Sep. 29, 2024
USD ($)
Jun. 30, 2024
USD ($)
Mar. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Oct. 01, 2023
USD ($)
Jan. 01, 2023
USD ($)
Oct. 02, 2022
USD ($)
Dec. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Goodwill [Line Items]                      
Number of reporting units | reporting_unit 2                    
Goodwill and intangible impairment                   $ 1,466 $ 712
Goodwill impairment measurement input 2                    
Goodwill   $ 1,113       $ 2,545   $ 3,239   1,113 2,545
Sensitivity analysis of intangible assets impairment additional charges impact of 300 basis points                   20  
Developed Technology Rights                      
Goodwill [Line Items]                      
Useful life (in years)         10 years            
Developed Technology Rights | Fluent Bio Sciences                      
Goodwill [Line Items]                      
Useful life (in years)   10 years 7 years                
Finite-lived intangible assets acquired   $ 19 $ 42                
Customer relationships | Fluent Bio Sciences                      
Goodwill [Line Items]                      
Useful life (in years)     11 years                
Finite-lived intangible assets acquired     $ 2                
GRAIL Inc                      
Goodwill [Line Items]                      
Goodwill potential impairment loss               $ 0      
Fair value in excess of carrying amount (more than)           $ 950         950
Business combination impairment test percentage           23.00%          
In-process research and development (IPR&D)                      
Goodwill [Line Items]                      
Goodwill fair value recorded impairment             $ 109     $ 3 6
Fair value of discount rate (as a percent)             19.00%        
In-process research and development (IPR&D) | Series of Individually Immaterial Business Acquisitions                      
Goodwill [Line Items]                      
Indefinite-lived intangible assets acquired         $ 35            
Spinoff | GRAIL Inc                      
Goodwill [Line Items]                      
Amount of continuing cash flows after disposal $ 974                    
Minimum | Spinoff | GRAIL Inc                      
Goodwill [Line Items]                      
GRAIL net assets       $ 400              
Maximum | Spinoff | GRAIL Inc                      
Goodwill [Line Items]                      
GRAIL net assets       770              
Measurement Input, Expected Term                      
Goodwill [Line Items]                      
Intangible assets impairment measurement input                   15  
GRAIL                      
Goodwill [Line Items]                      
Goodwill amount that exceeds carrying value 580                    
Goodwill and intangible impairment       1,466     $ 712   $ 3,914    
Goodwill             $ 3,600        
Fair value of discount rate (as a percent)             24.00%   22.00%    
GRAIL | In-process research and development (IPR&D)                      
Goodwill [Line Items]                      
Goodwill fair value recorded impairment       $ 420              
GRAIL | Minimum                      
Goodwill [Line Items]                      
Goodwill           $ 3,000         $ 3,000
Goodwill impairment increase in discounted cash flow model discount rate             0.0050        
Goodwill potential impairment loss             $ 200        
GRAIL | Maximum                      
Goodwill [Line Items]                      
Goodwill $ 4,000                    
Goodwill impairment increase in discounted cash flow model discount rate             0.0100        
Goodwill potential impairment loss             $ 350        
GRAIL | Measurement Input Cash Flow Period Member | Valuation Technique, Discounted Cash Flow                      
Goodwill [Line Items]                      
Goodwill impairment measurement input 15                    
GRAIL | Measurement Input, Discount Rate | Valuation Technique, Discounted Cash Flow                      
Goodwill [Line Items]                      
Intangible assets impairment measurement input 0.465                    
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS - Schedule of Identifiable Intangible Assets (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 748 $ 3,164
Accumulated Amortization (453) (761)
Impairment   0
Intangible Assets, Net 295 2,403
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Gross Carrying Amount 748 3,869
Accumulated Amortization (453) (761)
Impairment   (115)
Intangible Assets, Net $ 295 $ 2,993
Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Goodwill and intangible impairment Goodwill and intangible impairment
Developed technologies    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 465 $ 2,807
Accumulated Amortization (305) (585)
Impairment   0
Intangible Assets, Net 160 2,222
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (305) (585)
Licensed technologies    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 234 274
Accumulated Amortization (114) (133)
Impairment   0
Intangible Assets, Net 120 141
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (114) (133)
License agreements    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 19 14
Accumulated Amortization (13) (13)
Impairment   0
Intangible Assets, Net 6 1
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (13) (13)
Customer relationships    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 16 14
Accumulated Amortization (14) (13)
Impairment   0
Intangible Assets, Net 2 1
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (14) (13)
Database    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 12 12
Accumulated Amortization (5) (3)
Impairment   0
Intangible Assets, Net 7 9
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (5) (3)
Trade name    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 2 43
Accumulated Amortization (2) (14)
Impairment   0
Intangible Assets, Net 0 29
Intangible Assets, Net (Excluding Goodwill) [Abstract]    
Accumulated Amortization (2) (14)
In-process research and development (IPR&D)    
Finite-Lived Intangible Assets [Line Items]    
In-process research and development (IPR&D) 0 705
Impairment   (115)
In-process research and development (IPR&D) $ 0 $ 590
v3.25.0.1
GOODWILL, INTANGIBLE ASSETS, AND ACQUISITIONS - Schedule of Estimated Annual Amortization of Intangible Assets (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Estimated Annual Amortization    
2025 $ 69  
2026 57  
2027 55  
2028 52  
2029 23  
Thereafter 39  
Total $ 295 $ 2,403
v3.25.0.1
DEBT AND OTHER COMMITMENTS - Schedule of Debt Obligations (Details) - Term Notes - USD ($)
Dec. 29, 2024
Sep. 09, 2024
Dec. 31, 2023
Dec. 31, 2022
Mar. 31, 2021
Debt Instrument [Line Items]          
Unamortized discounts and debt issuance costs $ (11,000,000)   $ (11,000,000)    
Net carrying amount of term debt 1,989,000,000   1,489,000,000    
Less: current portion 499,000,000   0    
Term debt, non-current 1,490,000,000   1,489,000,000    
Level 2          
Debt Instrument [Line Items]          
Fair value of term debt outstanding (Level 2) 1,940,000,000   1,440,000,000    
2025 Term Notes          
Debt Instrument [Line Items]          
Principal amount of notes outstanding 500,000,000   500,000,000 $ 500,000,000  
2026 Term Notes          
Debt Instrument [Line Items]          
Principal amount of notes outstanding 500,000,000 $ 500,000,000 0    
2027 Term Notes          
Debt Instrument [Line Items]          
Principal amount of notes outstanding 500,000,000   500,000,000 $ 500,000,000  
2031 Term Notes          
Debt Instrument [Line Items]          
Principal amount of notes outstanding $ 500,000,000   $ 500,000,000   $ 500,000,000
v3.25.0.1
DEBT AND OTHER COMMITMENTS - Narrative (Details)
1 Months Ended 12 Months Ended
Sep. 09, 2024
USD ($)
Jun. 17, 2024
USD ($)
Jan. 04, 2023
USD ($)
one_year_extension
consecutive_fiscal_quarter
Dec. 31, 2022
USD ($)
Mar. 31, 2021
USD ($)
Dec. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Jun. 20, 2024
USD ($)
Jan. 03, 2022
USD ($)
Aug. 31, 2018
USD ($)
Aug. 21, 2018
Debt Instrument [Line Items]                        
Additional paid-in capital           $ 7,525,000,000 $ 9,555,000,000          
Retained earnings (accumulated deficit)           (1,242,000,000) (19,000,000)          
Purchase obligation           212,000,000            
Cumulative Effect, Period of Adoption, Adjustment | ASU 2020-06                        
Debt Instrument [Line Items]                        
Additional paid-in capital                   $ 93,000,000    
Retained earnings (accumulated deficit)                   $ 61,000,000    
Term Notes                        
Debt Instrument [Line Items]                        
Interest expense recognized           $ 99,000,000 74,000,000 $ 21,000,000        
Proceeds from the issuance       $ 991,000,000 $ 992,000,000              
Redemption price         100.00% 100.00%            
Term Notes | 2026 Term Notes                        
Debt Instrument [Line Items]                        
Stated rate 4.65%         4.65%            
Principal amount of notes outstanding $ 500,000,000         $ 500,000,000 0          
Proceeds from the issuance 497,000,000                      
Term Notes | 2025 Term Notes                        
Debt Instrument [Line Items]                        
Stated rate       5.80%                
Principal amount of notes outstanding       $ 500,000,000   500,000,000 500,000,000          
Term Notes | 2027 Term Notes                        
Debt Instrument [Line Items]                        
Stated rate       5.75%                
Principal amount of notes outstanding       $ 500,000,000   500,000,000 500,000,000          
Term Notes | 2023 Term Notes                        
Debt Instrument [Line Items]                        
Stated rate         0.55%              
Principal amount of notes outstanding         $ 500,000,000              
Term Notes | 2031 Term Notes                        
Debt Instrument [Line Items]                        
Stated rate         2.55%              
Principal amount of notes outstanding         $ 500,000,000 500,000,000 $ 500,000,000          
Term Notes | Delayed Draw Credit Facility Due 2025                        
Debt Instrument [Line Items]                        
Stated rate   6.70%                    
Principal amount of notes outstanding   $ 750,000,000             $ 750,000,000      
Debt instrument term   364 days                    
Repayments of long-term debt $ 761,000,000                      
Repayments of long-term debt           $ 5,000,000            
Convertible Senior Notes | 2023 Notes                        
Debt Instrument [Line Items]                        
Stated rate                       0.00%
Principal amount of notes outstanding                     $ 750,000,000  
Effective interest rate used to measure fair value of convertible senior note                     3.70%  
Debt, fair value                     $ 624,000,000  
Additional paid in capital, before tax                     126,000,000  
Additional paid-in capital                     $ 93,000,000  
Line of Credit | Revolving Credit Agreement | Revolving Credit Facility                        
Debt Instrument [Line Items]                        
Maximum borrowing capacity     $ 750,000,000                  
Line of Credit | Revolving Credit Agreement | Swingline Borrowings                        
Debt Instrument [Line Items]                        
Debt instrument term     5 years                  
Maximum borrowing capacity     $ 40,000,000                  
Debt instrument, number of one year extensions | one_year_extension     2                  
Debt instrument, extension term     1 year                  
Line of Credit | Credit Agreement | Letter of Credit                        
Debt Instrument [Line Items]                        
Maximum borrowing capacity     $ 50,000,000                  
Unsecured Debt | Revolving Credit Agreement                        
Debt Instrument [Line Items]                        
Debt instrument, basis spread on variable rate     0.10%                  
Debt instrument, face amount, optional increase in additional borrowings     $ 250,000,000                  
Number of consecutive fiscal quarters, minimum debt to EBITDA ratio | consecutive_fiscal_quarter     4                  
Debt instrument, covenant, minimum debt to EBITDA ratio     3.50                  
Debt instrument, covenant, minimum debt to EBITDA ratio upon consummation of acquisition     4.00                  
Number of consecutive fiscal quarters, minimum debt to EBITDA ratio upon consummation of acquisition | consecutive_fiscal_quarter     3                  
v3.25.0.1
DEBT AND OTHER COMMITMENTS - Schedule of Maturities of Operating Lease Liabilities (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Debt Disclosure [Abstract]    
2025 $ 105  
2026 105  
2027 103  
2028 84  
2029 81  
Thereafter 275  
Total remaining lease payments 753  
Less: imputed interest (120)  
Total operating lease liabilities 633  
Less: current portion (79) $ (86)
Long-term operating lease liabilities $ 554 $ 687
Weighted-average remaining lease term 8 years  
Weighted-average discount rate 4.40%  
v3.25.0.1
DEBT AND OTHER COMMITMENTS - Schedule of Lease Costs (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Debt Disclosure [Abstract]      
Operating lease costs $ 93 $ 116 $ 112
Sublease income (19) (20) (20)
Variable lease costs 25 27 20
Total lease costs $ 99 $ 123 $ 112
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative (Details) - 2015 Stock Plan - shares
shares in Thousands
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Shares authorized (in shares)   8,000
Number of shares available for grant 160  
Shares available for issuance (in shares) 5,400  
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative - Restricted Stock (Details)
12 Months Ended
Dec. 29, 2024
award
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Number of PSU awards 3
RSU  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Share based compensation vesting performance period 4 years
PSU  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Share based compensation vesting performance period 3 years
Market Based Performance Stock Units  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Share-based compensation arrangement by share-based payment award, maximum award payout 175.00%
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Restricted Stock Activity and Related Information (Details) - $ / shares
shares in Thousands
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
RSU      
Stock Units      
Outstanding at period start (in shares) 2,198,000 1,611,000 1,130,000
Awarded (in shares) (2,788,000) (2,032,000) (1,370,000)
Unvested adjustment (in shares) 107,000    
Vested (in shares) (771,000) (987,000) (707,000)
Cancelled (in shares) (443,000) (458,000) (182,000)
Outstanding at period end (in shares) 3,879,000 2,198,000 1,611,000
Weighted-Average Grant- Date Fair Value per Share      
Outstanding at period start (in dollars per share) $ 236.32 $ 311.23 $ 345.66
Awarded (in dollars per share) 133.73 195.94 302.52
Unvested adjustment (in dollars per share) 0    
Vested (in dollars per share) 249.70 268.08 341.56
Cancelled (in dollars per share) 195.11 253.52 341.14
Outstanding at period end (in dollars per share) $ 158.60 $ 236.32 $ 311.23
PSU      
Stock Units      
Outstanding at period start (in shares) 0 74 328
Awarded (in shares) (729) (39) (108)
Unvested adjustment (in shares) 12    
Vested (in shares) 0 0 (99)
Cancelled (in shares) (41) (113) (47)
Outstanding at period end (in shares) 700 0 74
Weighted-Average Grant- Date Fair Value per Share      
Outstanding at period start (in dollars per share) $ 0 $ 446.74 $ 466.42
Awarded (in dollars per share) 164.38 239.98 479.85
Unvested adjustment (in dollars per share) 0    
Vested (in dollars per share) 0 0 492.55
Cancelled (in dollars per share) 167.68 299.98 411.78
Outstanding at period end (in dollars per share) $ 164.87 $ 0 $ 446.74
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Pre-tax Intrinsic Values and Total Fair Value of Vested Restricted Stock (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
RSU      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax intrinsic value of outstanding restricted stock: $ 525 $ 306 $ 326
Fair value of restricted stock vested: 116 122 162
PSU      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax intrinsic value of outstanding restricted stock: 95 0 15
Fair value of restricted stock vested: $ 0 $ 0 $ 49
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Stock Option Activity Under all Stock Option Plans (Details) - $ / shares
shares in Thousands
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Options      
Options and Performance Stock Options      
Outstanding at period start (in shares) 35 187 8
Granted (in shares)     180
Exercised (in shares)   (8) (1)
Cancelled (in shares) (35) (144)  
Outstanding at period end (in shares) 0 35 187
Weighted-Average Exercise Price      
Outstanding at period start (in dollars per share) $ 330.25 $ 319.72 $ 66.42
Granted (in dollars per share)     330.25
Exercised (in dollars per share)   71.09 6.55
Cancelled (in dollars per share) 330.25 330.25  
Outstanding at period end (in dollars per share) $ 0 $ 330.25 $ 319.72
Performance Stock Options      
Options and Performance Stock Options      
Outstanding at period start (in shares) 16 17 17
Granted (in shares)     0
Exercised (in shares)   (1) 0
Cancelled (in shares) (16) 0  
Outstanding at period end (in shares) 0 16 17
Weighted-Average Exercise Price      
Outstanding at period start (in dollars per share) $ 87.74 $ 85.54 $ 85.54
Granted (in dollars per share)     0
Exercised (in dollars per share)   16.69 0
Cancelled (in dollars per share) 87.74 0  
Outstanding at period end (in dollars per share) $ 0 $ 87.74 $ 85.54
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative - Liability-Classified Awards (Details) - USD ($)
$ in Millions
12 Months Ended
Jun. 24, 2024
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Jul. 02, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense   $ 371 $ 380 $ 366  
Spinoff | GRAIL          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Period of continuing involvement after disposal 2 years 6 months 2 years 6 months      
Non-contingent indemnification liability (see Note 7)   $ 1      
Liability Classified Restricted Stock Units          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Liability-classified awards (in shares)   0 0   557,000
Liability-Based Awards          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Award expiration period   4 years      
Share based compensation vesting performance period   4 years      
Share-based compensation expense   $ 52 $ 95 $ 67  
Aggregated potential value   $ 78      
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Cash-Based Equity Incentive Award Activity (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Share-Based Compensation Arrangement By Share-Based Payment Award, Liability-Classified Awards [Roll Forward]      
Liability-classified equity incentive awards $ 0 $ 55  
Liability-Based Awards      
Share-Based Compensation Arrangement By Share-Based Payment Award, Liability-Classified Awards [Roll Forward]      
Beginning balance 292 293 $ 184
Granted 67 116 168
Vested and paid in cash (54) (77) (41)
Cancelled (13) (32) (41)
Change in fair value (9) (8) 23
Derecognition for GRAIL Spin-Off (283)    
Ending balance 0 $ 292 $ 293
Liability-classified equity incentive awards $ 53    
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative - Employee Stock Purchase Plan (Details) - Employee Stock - ESPP - shares
shares in Thousands
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Specified percentage of the fair market value of the common stock on the first or last day of the offering period whichever is lower at which stock is purchased 85.00%    
Shares issued in period (in shares) 500 400 300
Shares available for issuance (in shares) 12,400    
Number of shares available for grant, period increase 500    
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan (Details) - $ / shares
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected dividends 0.00%    
Employee Stock      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk-free interest rate, minimum 4.35% 0.78% 0.06%
Risk-free interest rate, maximum 5.54% 5.54% 2.98%
Expected volatility, minimum 41.00% 41.00% 37.00%
Expected volatility, maximum 49.00% 51.00% 51.00%
Expected dividends 0.00% 0.00% 0.00%
Weighted-average grant-date fair value per share (in dollars per share) $ 37.24 $ 49.87 $ 50.22
Employee Stock | Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 6 months 6 months 6 months
Employee Stock | Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 1 year 1 month 6 days 1 year 1 month 6 days 1 year
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative - Share Repurchases (Details) - USD ($)
shares in Thousands
1 Months Ended 12 Months Ended
Feb. 11, 2025
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Aug. 31, 2024
Class of Stock [Line Items]          
Repurchase of common shares (in shares)   904      
Total cost of shares repurchased   $ 116,000,000      
Common Stock          
Class of Stock [Line Items]          
Stock repurchase program authorized amount         $ 1,500,000,000
Dollar amount remaining in authorized stock repurchase program   $ 1,400,000,000      
Repurchase of common shares (in shares)     0 0  
Common Stock | Subsequent Event          
Class of Stock [Line Items]          
Repurchase of common shares (in shares) 1,000        
Total cost of shares repurchased $ 126,000,000        
v3.25.0.1
STOCKHOLDERS’ EQUITY - Schedule of Share Repurchase Activity (Details)
shares in Thousands, $ in Millions
12 Months Ended
Dec. 29, 2024
USD ($)
shares
Equity [Abstract]  
Number of shares repurchased (in shares) | shares 904
Total cost of shares repurchased | $ $ 116
v3.25.0.1
STOCKHOLDERS' EQUITY - Schedule of Share-Based Compensation Expense for all Stock Awards (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes $ 371 $ 380 $ 366
Related income tax benefits (83) (87) (83)
Share-based compensation expense, net of taxes 288 293 283
Cost of product revenue      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 25 29 26
Cost of service and other revenue      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 6 7 6
Research and development      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 146 155 153
Selling, general and administrative      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes $ 194 $ 189 $ 181
v3.25.0.1
STOCKHOLDERS' EQUITY - Narrative - Share-Based Compensation (Details)
$ in Millions
12 Months Ended
Dec. 29, 2024
USD ($)
Equity [Abstract]  
Unrecognized compensation cost $ 565
Weighted-average period of unrecognized compensation cost 2 years 6 months
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Schedule of Accounts Receivable (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Trade accounts receivable, gross $ 744 $ 741
Allowance for credit losses (9) (7)
Total accounts receivable, net $ 735 $ 734
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Schedule of Inventory (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Raw materials $ 225 $ 276
Work in process 404 402
Finished goods 31 30
Inventory, gross 660 708
Inventory reserve (113) (121)
Total inventory, net $ 547 $ 587
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Schedule of Property and Equipment (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 2,069 $ 2,145
Accumulated depreciation (1,254) (1,138)
Total property and equipment, net 815 1,007
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 772 803
Machinery and equipment    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 683 684
Computer hardware and software    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 478 463
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 53 55
Buildings    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 44 44
Construction in progress    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 39 $ 96
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Schedule of Accrued Liabilities (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Legal contingencies $ 26 $ 484
Contract liabilities, current portion 260 252
Accrued compensation expenses 252 223
Accrued taxes payable 101 79
Operating lease liabilities, current portion $ 79 $ 86
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Long-term operating lease liabilities Long-term operating lease liabilities
Liability-classified equity incentive awards $ 0 $ 55
Other, including warranties 109 146
Total accrued liabilities $ 827 $ 1,325
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Schedule of Changes in Reserve for Product Warranties (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Movement in Standard and Extended Product Warranty Accrual, Increase (Decrease) [Roll Forward]      
Balance as of beginning of period $ 21 $ 18 $ 22
Additions charged to cost of product revenue 42 42 23
Repairs and replacements (45) (39) (27)
Balance as of end of period $ 18 $ 21 $ 18
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Pre-Tax Restructuring Charge (Details) - USD ($)
$ in Millions
12 Months Ended 21 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Dec. 29, 2024
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges $ 62 $ 152 $ 214
Selling, general and administrative      
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges 59 122  
Research and development      
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges 2 24  
Employee separation costs      
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges 12 48 60
Asset impairment charges      
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges 46 100 146
Other Costs      
Restructuring Cost and Reserve [Line Items]      
Total restructuring charges $ 4 $ 4 $ 8
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Narrative - Restructuring (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Restructuring Cost and Reserve [Line Items]    
Right-of-use asset impairment   $ 38
Right-of-use assets and leasehold improvements   21
Operating lease right-of-use assets $ 419 544
CALIFORNIA    
Restructuring Cost and Reserve [Line Items]    
Operating lease right-of-use assets 100  
Leasehold improvements 100  
Foster City, California    
Restructuring Cost and Reserve [Line Items]    
Right-of-use asset impairment 12  
San Diego, California    
Restructuring Cost and Reserve [Line Items]    
Right-of-use asset impairment 19  
Leasehold improvements    
Restructuring Cost and Reserve [Line Items]    
Right-of-use asset impairment $ 14 16
Right-of-use assets and leasehold improvements   $ 22
v3.25.0.1
SUPPLEMENTAL BALANCE SHEET DETAILS - Pre-Tax Charges and Total Costs (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Restructuring Reserve [Roll Forward]    
Beginning balance $ 18 $ 0
Expense recorded $ 16 52
Restructuring Incurred Cost Statement Of Income Or Comprehensive Income Extensible Enumeration Not Disclosed Flag Expense recorded  
Cash payments $ (26) (34)
Adjustments to accrual (4)  
Ending balance 4 18
Employee Separation Costs    
Restructuring Reserve [Roll Forward]    
Beginning balance 17 0
Expense recorded 12 48
Cash payments (24) (31)
Adjustments to accrual (3)  
Ending balance 2 17
Other Costs    
Restructuring Reserve [Roll Forward]    
Beginning balance 1 0
Expense recorded 4 4
Cash payments (2) (3)
Adjustments to accrual (1)  
Ending balance $ 2 $ 1
v3.25.0.1
LEGAL PROCEEDINGS (Details)
$ in Millions
3 Months Ended 12 Months Ended
Jun. 24, 2024
Nov. 11, 2023
lawsuit
Sep. 29, 2024
USD ($)
Dec. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Sep. 03, 2024
USD ($)
Feb. 02, 2024
lawsuit
Jan. 09, 2024
movant
Oct. 01, 2023
Loss Contingencies [Line Items]                    
Legal contingency and settlement       $ 456 $ (20) $ (619)        
Loss contingency, new claims filed, number | lawsuit   3                
Commitments and contingencies, number of movants filed motions consolidate actions | movant                 4  
Commitments and contingencies, number of additional securities class actions | lawsuit               2    
Acquisition Of Grail, Inc.                    
Loss Contingencies [Line Items]                    
Loss contingency accrual             $ 432      
Legal contingency and settlement     $ 481              
Litigation settlement, gain     489              
Litigation settlement, loss     $ 8              
Long-term debt, fine percentage rate                   0.055
Complete Genomics                    
Loss Contingencies [Line Items]                    
Payments for legal settlements       325            
Payments for legal settlements, amount allocated to release of past damages claimed       150            
Former gain contingency, recognized in current period       5            
Complete Genomics | License                    
Loss Contingencies [Line Items]                    
License granted intangible assets       $ 180            
Finite-lived intangible assets, remaining amortization period       6 years 6 months            
Spinoff | GRAIL                    
Loss Contingencies [Line Items]                    
Percent of interest disposed 85.50%                  
v3.25.0.1
INCOME TAXES - Schedule of (Loss) Income before Income Taxes by Region (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Income Tax Disclosure [Abstract]      
United States $ (1,834) $ (1,735) $ (4,942)
Foreign 655 618 606
Total loss before income taxes $ (1,179) $ (1,117) $ (4,336)
v3.25.0.1
INCOME TAXES - Schedule of Provision for Income Taxes (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Current:      
Federal $ 6 $ (5) $ (11)
State 18 6 27
Foreign 137 77 75
Total current provision 161 78 91
Deferred:      
Federal (59) (13) 40
State (56) (26) (47)
Foreign (2) 5 (16)
Total deferred benefit (117) (34) (23)
Total tax provision $ 44 $ 44 $ 68
v3.25.0.1
INCOME TAXES - Schedule of Reconciliation of Provision for (Loss) Income Taxes to Amount Computed by Applying the Federal Statutory Rate (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Income Tax Disclosure [Abstract]      
Tax at federal statutory rate $ (248) $ (235) $ (911)
State, net of federal benefit (38) (16) (9)
Research and other credits (32) (42) (46)
Change in valuation allowance 29 48 62
Impact of R&D expense capitalization 52 86 87
Impact of net operating losses on GILTI, U.S. foreign tax credits, and Pillar Two global minimum top-up tax 90 61 60
Impact of foreign operations 3 (50) (81)
Stock compensation 16 31 20
Accrual of European Commission fine (99) 3 96
Goodwill impairment 308 149 822
Impact of acquisition related items (46) 8 (27)
Other 9 1 (5)
Total tax provision $ 44 $ 44 $ 68
v3.25.0.1
INCOME TAXES - Schedule of Significant Components of Deferred Tax Assets and Liabilities (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Deferred tax assets:    
Net operating losses $ 189 $ 392
Tax credits 252 211
Other accruals and reserves 40 49
Stock compensation 34 15
Capitalized U.S. R&D expenses 181 158
Other amortization 42 115
Operating lease liabilities 112 146
Property and equipment 17 4
Investments 23 7
Other 63 56
Total gross deferred tax assets 953 1,153
Valuation allowance on deferred tax assets (278) (251)
Total deferred tax assets 675 902
Deferred tax liabilities:    
Purchased intangible amortization (35) (734)
Operating lease right-of-use assets (57) (88)
Other (25) (25)
Total deferred tax liabilities (117) (847)
Deferred tax assets, net $ 558 $ 55
v3.25.0.1
INCOME TAXES - Narrative (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Tax Credit Carryforward [Line Items]      
Valuation allowance on deferred tax assets $ 278 $ 251  
Uncertain tax positions that would reduce annual effective tax rate, if recognized 202 156  
Potential interest penalties (income) on uncertain tax positions 6 2 $ (3)
Liability recorded for potential interest and penalties 13 6  
Tax Year 2017      
Tax Credit Carryforward [Line Items]      
Undistributed earnings of foreign subsidiaries 1,806    
Deferred tax liability for undistributed foreign earnings 24    
Federal      
Tax Credit Carryforward [Line Items]      
Tax credit carryforwards 140    
Federal | IRS      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 74    
State      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 1,872    
Tax credit carryforwards 239    
Foreign | Singapore      
Tax Credit Carryforward [Line Items]      
Decrease to the provision for income taxes $ 33 $ 75 $ 56
Increase to net income per diluted share (in dollars per share) $ 0.20 $ 0.47 $ 0.35
v3.25.0.1
INCOME TAXES - Schedule of the Gross Amount of Uncertain Tax Positions (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Unrecognized Tax Benefits [Roll Forward]      
Balance at beginning of year $ 210 $ 153 $ 131
Increases related to prior year tax positions 2 27 12
Decreases related to prior year tax positions (2) (2) (3)
Increases related to current year tax positions 23 42 42
Decreases related to lapse of statute of limitations (1) (10) (29)
Balance at end of year $ 232 $ 210 $ 153
v3.25.0.1
EMPLOYEE BENEFIT PLANS (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Matching contributions $ 34 $ 36 $ 30
Employer contribution vesting percent upon the occurrence of participant's disability, death or retirement or change in control of the Company 100.00%    
Deferred compensation plan assets $ 70 61  
Deferred compensation liability $ 65 $ 59  
Senior Level Employee      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Percent of base salary available for contribution to the deferred compensation plan 60.00%    
Percent of all other forms of compensation available for contribution to the deferred compensation plan 100.00%    
Director      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Percent of all other forms of compensation available for contribution to the deferred compensation plan 100.00%    
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION - Narrative (Details)
12 Months Ended
Dec. 29, 2024
segment
Segment Reporting [Abstract]  
Number of reportable segment 1
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION - Schedule of Operating Performance and Assets by Segment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Segment Reporting Information [Line Items]      
Revenue $ 4,372 $ 4,504 $ 4,584
Total operating expenses 3,694 3,813 7,151
Cost of revenue 1,511 1,760 1,612
Research and development 1,169 1,354 1,321
Goodwill and intangible impairment 1,889 827 3,914
Legal contingency and settlement (456) 20 619
Consolidated other expense, net 346 48 157
Provision for income taxes 44 44 68
Net loss (1,223) (1,161) (4,404)
Operating Segments | Core Illumina      
Segment Reporting Information [Line Items]      
Revenue 4,332 4,438 4,553
Cost of revenue 1,424 1,582 1,446
Research and development 988 1,030 1,004
Selling and marketing 638 648 677
General and administrative 262 600 326
Goodwill and intangible impairment 3 6 0
Legal contingency and settlement (456) 20 619
Net loss 1,473 552 481
Operating Segments | GRAIL      
Segment Reporting Information [Line Items]      
Revenue 55 93 55
Total operating expenses 2,360 1,714 4,712
Consolidated other expense, net 346 48 157
Provision for income taxes 44 44 68
Eliminations      
Segment Reporting Information [Line Items]      
Net loss (1) 0 (3)
Eliminations | Core Illumina      
Segment Reporting Information [Line Items]      
Cost of revenue $ 15 $ 26 $ 24
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION - Reconciliation of Operating Profit (Loss) from Segments to Consolidated (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Jan. 01, 2023
Segment Reporting Information [Line Items]      
Consolidated depreciation and amortization $ 354 $ 432 $ 394
Consolidated capital expenditures 142 195 286
Eliminations      
Segment Reporting Information [Line Items]      
Consolidated capital expenditures 0 (1) 0
Operating Segments | Core Illumina      
Segment Reporting Information [Line Items]      
Consolidated depreciation and amortization 280 273 240
Consolidated capital expenditures 137 183 262
Operating Segments | GRAIL      
Segment Reporting Information [Line Items]      
Consolidated depreciation and amortization 74 159 154
Consolidated capital expenditures $ 5 $ 13 $ 24
v3.25.0.1
SEGMENT AND GEOGRAPHIC INFORMATION - Schedule of Net Long-lived Assets Consisting of Property and Equipment (Details) - USD ($)
$ in Millions
Dec. 29, 2024
Dec. 31, 2023
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total long-lived assets, net $ 1,234 $ 1,551
United States    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total long-lived assets, net 750 1,040
Singapore    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total long-lived assets, net 279 298
United Kingdom    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total long-lived assets, net 124 136
Other countries    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total long-lived assets, net $ 81 $ 77