ILLUMINA, INC., 10-K filed on 2/16/2024
Annual Report
v3.24.0.1
Cover Page - USD ($)
$ in Billions
12 Months Ended
Dec. 31, 2023
Feb. 09, 2024
Jul. 02, 2023
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2023    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-35406    
Entity Registrant Name Illumina, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 33-0804655    
Entity Address, Address Line One 5200 Illumina Way    
Entity Address, City or Town San Diego    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 92122    
City Area Code 858    
Local Phone Number 202-4500    
Title of 12(b) Security Common Stock, $0.01 par value    
Trading Symbol ILMN    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Common Stock, Shares Outstanding   158,900,000  
Entity Public Float     $ 26.5
Documents Incorporated by Reference
Portions of the registrant’s definitive proxy statement for the 2024 annual meeting of stockholders are incorporated by reference into Items 10 through 14 of Part III of this Report.
   
Entity Central Index Key 0001110803    
Document Fiscal Year Focus 2023    
Document Fiscal Period Focus FY    
Amendment Flag false    
v3.24.0.1
Audit Information
12 Months Ended
Dec. 31, 2023
Audit Information [Abstract]  
Auditor Firm ID 42
Auditor Name Ernst & Young LLP
Auditor Location San Diego, California
v3.24.0.1
CONSOLIDATED BALANCE SHEETS - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Current assets:    
Cash and cash equivalents $ 1,048 $ 2,011
Short-term investments 6 26
Accounts receivable, net 734 671
Inventory, net 587 568
Prepaid expenses and other current assets 234 285
Total current assets 2,609 3,561
Property and equipment, net 1,007 1,091
Operating lease right-of-use assets 544 653
Goodwill 2,545 3,239
Intangible assets, net 2,993 3,285
Other assets 413 423
Total assets 10,111 12,252
Current liabilities:    
Accounts payable 245 293
Accrued liabilities 1,325 1,232
Term notes, current portion 0 500
Convertible senior notes, current portion 0 748
Total current liabilities 1,570 2,773
Operating lease liabilities 687 744
Term notes 1,489 1,487
Other long-term liabilities 620 649
Commitments and contingencies
Stockholders’ equity:    
Preferred stock, $0.01 par value, 10 million shares authorized; no shares issued and outstanding at December 31, 2023 and January 1, 2023 0 0
Common stock, $0.01 par value, 320 million shares authorized; 199 million shares issued and 159 million outstanding at December 31, 2023; 198 million shares issued and 158 million outstanding at January 1, 2023 2 2
Additional paid-in capital 9,555 9,207
Accumulated other comprehensive (loss) income (1) 3
(Accumulated deficit) retained earnings (19) 1,142
Treasury stock, 40 million shares at both December 31, 2023 and January 1, 2023 (3,792) (3,755)
Total stockholders’ equity 5,745 6,599
Total liabilities and stockholders’ equity $ 10,111 $ 12,252
v3.24.0.1
CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares
Dec. 31, 2023
Jan. 01, 2023
Statement of Financial Position [Abstract]    
Common stock, par value (in dollars per share) $ 0.01 $ 0.01
Common stock, shares authorized (in shares) 320,000,000 320,000,000
Common stock, shares issued (in shares) 199,000,000 198,000,000
Common stock, shares outstanding (in shares) 159,000,000 158,000,000
Treasury stock, common shares (in shares) 40,000,000 40,000,000
Preferred stock, par value (in dollars per share) $ 0.01 $ 0.01
Preferred stock, shares issued (in shares) 0 0
Preferred stock, shares outstanding (in shares) 0 0
Preferred stock, shares authorized (in shares) 10,000,000 10,000,000
v3.24.0.1
CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Millions, $ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Revenue:      
Total revenue $ 4,504 $ 4,584 $ 4,526
Cost of revenue:      
Amortization of acquired intangible assets 191 173 71
Total cost of revenue 1,760 1,612 1,372
Gross profit 2,744 2,972 3,154
Operating expense:      
Research and development 1,354 1,321 1,185
Selling, general and administrative 1,612 1,297 2,092
Goodwill and intangible impairment 827 3,914 0
Legal contingency and settlement 20 619 0
Total operating expense 3,813 7,151 3,277
Loss from operations (1,069) (4,179) (123)
Other income (expense):      
Interest income 58 11 0
Interest expense (77) (26) (61)
Other (expense) income, net (29) (142) 1,068
Total other (expense) income, net (48) (157) 1,007
(Loss) income before income taxes (1,117) (4,336) 884
Provision for income taxes 44 68 122
Net (loss) income $ (1,161) $ (4,404) $ 762
(Loss) earnings per share:      
Basic (in dollars per share) $ (7.34) $ (28.00) $ 5.07
Diluted (in dollars per share) $ (7.34) $ (28.00) $ 5.04
Shares used in computing (loss) earnings per share:      
Basic (in shares) 158 157 150
Diluted (in shares) 158 157 151
Product revenue      
Revenue:      
Total revenue $ 3,787 $ 3,953 $ 3,968
Cost of revenue:      
Cost of revenue 1,177 1,144 1,060
Service and other revenue      
Revenue:      
Total revenue 717 631 558
Cost of revenue:      
Cost of revenue $ 392 $ 295 $ 241
v3.24.0.1
CONSOLIDATED STATEMENTS OF COMPREHENSIVE (LOSS) INCOME - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Statement of Comprehensive Income [Abstract]      
Net (loss) income $ (1,161) $ (4,404) $ 762
Unrealized (loss) gain on cash flow hedges, net of deferred tax (4) (14) 16
Unrealized loss on available-for-sale debt securities, net of deferred tax 0 0 (1)
Total comprehensive (loss) income $ (1,165) $ (4,418) $ 777
v3.24.0.1
CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
shares in Millions, $ in Millions
Total
Cumulative Effect, Period of Adoption, Adjustment
Common Stock
Additional Paid-In Capital
Additional Paid-In Capital
Cumulative Effect, Period of Adoption, Adjustment
Accumulated Other Comprehensive Income (Loss)
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit)
Cumulative Effect, Period of Adoption, Adjustment
Treasury Stock
Beginning balance (in shares) at Jan. 03, 2021     195            
Beginning balance at Jan. 03, 2021 $ 4,694   $ 2 $ 3,815   $ 2 $ 4,723   $ (3,848)
Beginning balance (in shares) at Jan. 03, 2021                 (49)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net (loss) income 762           762    
Unrealized loss on available-for-sale debt securities, net of deferred tax (1)         (1)      
Unrealized (loss) gain on cash flow hedges, net of deferred tax 16         16      
Issuance of common stock, net of repurchases (in shares)     2           1
Issuance of common stock, net of repurchases (31)     60         $ (91)
GRAIL acquisition (in shares)                 10
GRAIL acquisition 4,986     4,749         $ 237
Exchange of GRAIL contingent value rights 2     2          
Share-based compensation 312     312          
Ending balance (in shares) at Jan. 02, 2022     197            
Ending balance at Jan. 02, 2022 10,740 $ (32) $ 2 8,938 $ (93) 17 5,485 $ 61 $ (3,702)
Ending balance (in shares) at Jan. 02, 2022                 (40)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net (loss) income (4,404)           (4,404)    
Unrealized loss on available-for-sale debt securities, net of deferred tax 0                
Unrealized (loss) gain on cash flow hedges, net of deferred tax (14)         (14)      
Issuance of common stock, net of repurchases (in shares)     1            
Issuance of common stock, net of repurchases 10     63         $ (53)
Share-based compensation $ 299     299          
Ending balance (in shares) at Jan. 01, 2023 158   198            
Ending balance at Jan. 01, 2023 $ 6,599   $ 2 9,207   3 1,142   $ (3,755)
Ending balance (in shares) at Jan. 01, 2023 (40)               (40)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Accounting Standards Update [Extensible List] ASU 2020-06                
Net (loss) income $ (1,161)           (1,161)    
Reclassification of liability-classified awards 9     9          
Unrealized loss on available-for-sale debt securities, net of deferred tax 0                
Unrealized (loss) gain on cash flow hedges, net of deferred tax (4)         (4)      
Issuance of common stock, net of repurchases (in shares)     1            
Issuance of common stock, net of repurchases 27     64         $ (37)
Share-based compensation $ 275     275          
Ending balance (in shares) at Dec. 31, 2023 159   199            
Ending balance at Dec. 31, 2023 $ 5,745   $ 2 $ 9,555   $ (1) $ (19)   $ (3,792)
Ending balance (in shares) at Dec. 31, 2023 (40)               (40)
v3.24.0.1
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Cash flows from operating activities:      
Net (loss) income $ (1,161) $ (4,404) $ 762
Adjustments to reconcile net (loss) income to net cash provided by operating activities:      
Depreciation expense 235 215 176
Amortization of intangible assets 197 179 75
Share-based compensation expense 380 366 754
Accretion of debt discount on convertible senior notes 0 0 32
Deferred income taxes (33) (23) (76)
Goodwill and intangible (IPR&D) impairment 827 3,914 0
Gain on previously held investment in GRAIL 0 0 (899)
Gain on exchange of GRAIL contingent value rights 0 0 (86)
Net losses (gains) on strategic investments 40 122 (18)
(Gain) loss on Helix contingent value right (10) 7 (30)
Payment of accreted debt discount (15) 0 0
Gain on derivative assets related to terminated acquisition 0 0 (26)
Property and equipment and right-of-use asset impairment 100 9 6
Change in fair value of contingent consideration liabilities (24) (205) 4
Unrealized loss on foreign exchange translation 22 1 0
Other 10 7 23
Changes in operating assets and liabilities:      
Accounts receivable (40) (12) (164)
Inventory (20) (135) (58)
Prepaid expenses and other current assets 11 16 (64)
Operating lease right-of-use assets and liabilities, net (16) (8) (13)
Other assets 5 19 (27)
Accounts payable (44) (38) 60
Accrued liabilities 15 381 101
Other long-term liabilities (1) (19) 13
Net cash provided by operating activities 478 392 545
Cash flows from investing activities:      
Maturities of available-for-sale securities 0 0 331
Purchases of available-for-sale securities 0 0 (77)
Sales of available-for-sale securities 0 0 1,031
Purchases of property and equipment (195) (286) (208)
Net (purchases) sales of strategic investments (6) (40) 246
Cash received for derivative assets related to terminated acquisition 0 0 52
Net cash paid for acquisitions (29) (85) (2,444)
Cash paid for intangible asset (1) (180) 0
Net cash used in investing activities (231) (591) (1,069)
Cash flows from financing activities:      
Debt issuance costs paid for credit facility (1) 0 0
Payments on financing obligations (1,235) 0 (517)
Payments on contingent consideration liabilities (1) 0 (71)
Net proceeds from issuance of debt 0 991 988
Proceeds from issuance of common stock 67 63 60
Taxes paid related to net share settlement of equity awards (40) (54) (511)
Net cash (used in) provided by financing activities (1,210) 1,000 (51)
Effect of exchange rate changes on cash and cash equivalents 0 (22) (3)
Net (decrease) increase in cash and cash equivalents (963) 779 (578)
Cash and cash equivalents at beginning of year 2,011 1,232 1,810
Cash and cash equivalents at end of year 1,048 2,011 1,232
Supplemental cash flow information:      
Cash paid for interest 73 17 9
Cash paid for income taxes 65 122 233
Cash paid for operating lease liabilities $ 123 $ 112 $ 96
v3.24.0.1
Organization and Significant Accounting Policies
12 Months Ended
Dec. 31, 2023
Accounting Policies [Abstract]  
Organization and Significant Accounting Policies
1. ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES
Business Overview

We are a provider of sequencing- and array-based solutions, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. Our customers include leading genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies.

On August 18, 2021, we acquired GRAIL, a healthcare company focused on early detection of multiple cancers. The acquisition is subject to ongoing legal proceedings, and, currently, GRAIL must be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission in the EC Divestment Decision, following the prohibition of our acquisition of GRAIL on September 6, 2022. Refer to note “8. Legal Proceedings” for additional details. We have included the financial results of GRAIL in our consolidated financial statements from the date of acquisition. On December 17, 2023, we announced that we will divest GRAIL.

Basis of Presentation

The consolidated financial statements have been prepared in conformity with U.S. generally accepted accounting principles (GAAP) and include our accounts, our wholly-owned subsidiaries, and majority-owned or controlled companies. All intercompany transactions and balances have been eliminated in consolidation. Certain prior period amounts have been reclassified to conform to the current period presentation.

Variable Interest Entities (VIEs)

We evaluate our ownership, contractual and other interests in entities that are not wholly-owned to determine if these entities are VIEs, and, if so, whether we are the primary beneficiary of the VIE. In determining whether we are the primary beneficiary of a VIE and therefore required to consolidate the VIE, we apply a qualitative approach that determines whether we have both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. We continuously perform this assessment, as changes to existing relationships or future transactions may result in the consolidation or deconsolidation of a VIE. As of December 31, 2023, there were no VIEs for which we were the primary beneficiary and for which we were required to consolidate.

Use of Estimates

The preparation of the consolidated financial statements requires that management make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses, and related disclosures of contingent assets and liabilities. Though macroeconomic factors such as inflation, exchange rate fluctuations and concerns about an economic downturn present additional uncertainty, we continue to use the best information available to inform our critical accounting estimates. Actual results could differ from those estimates.

Fiscal Year

Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. References to 2023, 2022, and 2021 refer to fiscal years ended December 31, 2023, January 1, 2023, and January 2, 2022, respectively. Fiscal years 2023, 2022, and 2021 were all 52 weeks.
Functional Currency

The U.S. dollar is the functional currency of our international operations. We re-measure foreign subsidiaries’ monetary assets and liabilities to the U.S. dollar and record the net gains or losses resulting from re-measurement in other (expense) income, net in the consolidated statements of operations.

Concentrations of Risk

Customers

We operate in markets that are highly competitive and rapidly changing. Significant technological changes, shifting customer needs, the emergence of competitive products or services with new capabilities, and other factors could negatively impact our operating results. A portion of our customers consist of university and research institutions that management believes are, to some degree, directly or indirectly supported by the United States Government. A significant change in current research funding, particularly with respect to the U.S. National Institutes of Health, could have an adverse impact on future revenues and results of operations.

International sales entail a variety of risks, including currency exchange fluctuations, longer payment cycles, and greater difficulty in accounts receivable collection. We are also subject to general geopolitical risks, such as political, social and economic instability, and changes in diplomatic and trade relations. The risks of international sales are mitigated in part by the extent to which sales are geographically distributed. Shipments to customers outside the United States comprised 48%, 50%, and 52% of total revenue in 2023, 2022, and 2021, respectively. Customers outside the United States represented 55% and 54% of our gross trade accounts receivable balance as of December 31, 2023 and January 1, 2023, respectively.

We had no customers that provided more than 10% of total revenue in 2023, 2022, and 2021. We perform regular reviews of customer activity and associated credit risks and do not require collateral or enter into netting arrangements. Historically, we have not experienced significant credit losses from accounts receivable.

Financial Instruments

We are also subject to risks related to our financial instruments, including cash and cash equivalents, investments, and accounts receivable. Most of our cash and cash equivalents as of December 31, 2023 were deposited with U.S. financial institutions, either domestically or with their foreign branches. Our investment policy restricts the amount of credit exposure to any one issuer to 5% of the portfolio or 5% of the total issue size outstanding at the time of purchase and to any one industry sector, as defined by Clearwater Analytics (Industry Sector Report), to 30% of the portfolio at the time of purchase. There is no limit to the percentage of the portfolio that may be maintained in debt securities, U.S. government-sponsored entities, U.S. Treasury securities, and money market funds. Historically, we have not experienced significant credit losses from financial instruments.

Suppliers

We require customized products and components that currently are available from a limited number of sources. We source certain key products and components included in our products from single vendors. Historically, we have not experienced significant issues sourcing materials to build our products.

Segments

We report segment information based on the management approach. This approach designates the internal reporting used by the Chief Operating Decision Maker (CODM) for making decisions and assessing performance as the source of our reportable segments. The CODM allocates resources and assesses the performance of each operating segment using information about its revenue and income (loss) from operations. Management evaluates the performance of our reportable segments based upon income (loss) from operations. Our CODM does not evaluate our operating segments using discrete asset information. We do not allocate expenses between segments.
Accounting Pronouncements Adopted in 2022

In August 2020, the FASB issued ASU 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity’s Own Equity (Subtopic 815-40). The new standard reduces the number of accounting models for convertible debt instruments, amends the accounting for certain contracts in an entity’s own equity, and modifies how certain convertible instruments and contracts that may be settled in cash or shares impact the calculation of diluted earnings per share. Specifically, the guidance removes certain accounting models that separate the embedded conversion features from the host contract for convertible instruments and requires the use of the if-converted method to calculate diluted earnings per share. We adopted the standard on its effective date in the first quarter of 2022 using a modified retrospective approach by recognizing a cumulative-effect adjustment to retained earnings on January 3, 2022. We did not restate prior periods. As a result of the adoption, we increased our convertible senior notes and retained earnings, on January 3, 2022, by $43 million and $61 million, respectively, and decreased our deferred tax liabilities, included in other long-term liabilities on the consolidated balance sheets, and additional paid-in capital by $11 million and $93 million, respectively. Interest expense recognized post-adoption has decreased as a result of accounting for our convertible senior notes as a single liability measured at amortized cost. See note “5. Debt and Other Commitments” for additional details on the adoption of ASU 2020-06.

Accounting Pronouncements Pending Adoption

In December 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280) - Improvements to Reportable Segment Disclosures. The new standard requires a company to disclose incremental segment information on an annual and interim basis, including significant segment expenses and measures of profit or loss that are regularly provided to the chief operating decision maker (CODM). The standard is effective for us beginning in fiscal year 2024 and interim periods within fiscal year 2025, with early adoption permitted. We do not expect to early adopt the new standard. We are currently evaluating the impact of ASU 2023-07 on the consolidated financial statements and related disclosures and will adopt the new standard using a retrospective approach.

In December 2023, the FASB also issued ASU 2023-09, Income Taxes (Topic 740) - Improvements to Income Tax Disclosures. The new standard requires a company to expand its existing income tax disclosures, specifically related to the rate reconciliation and income taxes paid. The standard is effective for us beginning in fiscal year 2025, with early adoption permitted. We do not expect to early adopt the new standard. The new standard is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2023-09 on the consolidated financial statements and related disclosures.

Revenue Recognition

Our revenue is generated primarily from the sale of products and services. Product revenue primarily consists of sales of instruments and consumables used in genetic analysis. Service and other revenue primarily consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and cancer detection testing services related to the GRAIL business.

We recognize revenue when control of our products and services is transferred to our customers in an amount that reflects the consideration we expect to receive from our customers in exchange for those products and services. This process involves identifying the contract with a customer, determining the performance obligations in the contract, determining the contract price, allocating the contract price to the distinct performance obligations in the contract, and recognizing revenue when the performance obligations have been satisfied. Revenue recognition for contracts with multiple deliverables is based on the separate satisfaction of each distinct performance obligation within the contract. A performance obligation is considered distinct from other obligations in a contract when it provides a benefit to the customer either on its own or together with other resources that are readily available to the customer and is separately identified in the contract. We consider a performance obligation satisfied once we have transferred control of a good or service to the customer, meaning the customer has the ability to use and obtain the benefit of the good or service. The contract price is allocated to each performance obligation in proportion to its standalone selling price. We determine our best estimate of standalone selling price using average selling prices over a rolling 12-month period coupled with an assessment of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, we rely upon prices set by management, adjusted for applicable discounts.

Revenue from product sales is recognized generally upon delivery to the end customer, which is when control of the product is deemed to be transferred. Invoicing typically occurs upon shipment and payment is typically due within 30
days from invoice. In instances where right of payment or transfer of title is contingent upon the customer’s acceptance of the product, revenue is deferred until all acceptance criteria have been met. Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer. Revenue from instrument service contracts is recognized as the services are rendered, typically evenly over the contract term. Revenue from development and licensing agreements generally includes upfront and periodic licensing fees, contract research and development services, or payments for development and regulatory milestones. Revenue for these agreements is recognized when each distinct performance obligation is satisfied.

Revenue is recorded net of discounts, distributor commissions, and sales taxes collected on behalf of governmental authorities. Employee sales commissions are recorded as selling, general and administrative expense when incurred as the amortization period for such costs, if capitalized, would have been one year or less.

In certain markets, products and services are sold to customers through distributors. In most sales through distributors, the product is delivered directly to customers by us. The terms of sales transactions through distributors are consistent with the terms of direct sales to customers.

(Loss) Earnings per Share

Basic (loss) earnings per share is computed based on the weighted average number of common shares outstanding during the period. Diluted (loss) earnings per share is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. In loss periods, basic and diluted loss per share are identical since the effect of potentially dilutive common shares is antidilutive and therefore excluded.

Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. On January 3, 2022, we adopted ASU 2020-06. As a result, beginning in Q1 2022, we utilize the if-converted method to calculate the impact of convertible senior notes on diluted (loss) earnings per share. Prior to the adoption of ASU 2020-06, we applied the treasury stock method when calculating the potential dilutive effect, if any, of convertible senior notes which we intended to settle or have settled in cash the principal outstanding. Under the treasury stock method, convertible senior notes would have a dilutive impact when the average market price of our common stock exceeded the applicable conversion price of the respective notes. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares.
The following table presents the calculation of weighted average shares used to calculate basic and diluted (loss) earnings per share:
 Years Ended
In millionsDecember 31,
2023
January 1,
2023
January 2,
2022
Weighted average shares outstanding158 157 150 
Effect of potentially dilutive common shares from:
Equity awards — 
Weighted average shares used in calculating diluted (loss) earnings per share158 157 151 
Antidilutive shares:
Convertible senior notes1 — 
Equity awards3 — 
Potentially dilutive shares excluded from calculation due to antidilutive effect4 — 
Fair Value Measurements

The fair value of assets and liabilities are based on the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value maximize the use of observable inputs and minimize the use of unobservable inputs. We use a fair value hierarchy with three levels of inputs, of which the first two are considered observable and the last unobservable, to measure fair value:

Level 1 — Quoted prices in active markets for identical assets or liabilities.
Level 2 — Inputs, other than Level 1, that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

The carrying amounts of financial instruments such as cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable, and accrued liabilities approximate the related fair values due to the short-term maturities of these instruments.

Cash Equivalents
Cash equivalents are comprised of short-term, highly-liquid investments with maturities of 90 days or less at the date of purchase.

Equity Securities and Investments

We have strategic investments in privately-held companies (non-marketable equity securities) and companies that have completed initial public offerings (marketable equity securities). Our marketable equity securities are measured at fair value. Our non-marketable equity securities without readily determinable market values are initially measured at cost and adjusted to fair value for observable transactions for identical or similar investments of the same issuer or impairment. Equity investments are classified as current, short-term investments, or noncurrent, recorded in other assets, based on the nature of the securities and their availability for use in current operations. Unrealized gains and losses on our equity investments are recorded in other (expense) income, net in the consolidated statements of operations. Our equity investments are assessed for impairment quarterly. Impairment losses, equal to the difference between the carrying value and the fair value of the investment, are recorded in other (expense) income, net.

We use the equity method to account for investments through which we have the ability to exercise significant influence, but not control, over the investee. Such investments are recorded in other assets, and our share of net income or loss is recognized on a one quarter lag in other (expense) income, net.

Accounts Receivable

Trade accounts receivable are recorded at the net invoice value and are not interest-bearing. Receivables are considered past due based on the contractual payment terms. We reserve a percentage of our trade receivable balance based on collection history and current economic trends that we expect will impact the level of credit losses over the life of our receivables. These reserves are re-evaluated on a regular basis and adjusted, as needed. Once a receivable is deemed to be uncollectible, such balance is charged against the reserve.

Inventory

Inventory is stated at the lower of cost or net realizable value, on a first-in, first-out basis. Inventory includes raw materials and finished goods that may be used in the research and development process, and such items are expensed as consumed or capitalized as property and equipment and depreciated. Inventory write-downs for slow-moving, excess, and obsolete inventories are estimated based on product life cycles, quality issues, historical experience, and usage forecasts.
Property and Equipment

Property and equipment are stated at cost, subject to review for impairment, and depreciated over the estimated useful lives of the assets, using the straight-line method. Depreciation of leasehold improvements is recorded over the shorter of the lease term or the estimated useful life of the related assets. Maintenance and repairs are expensed as incurred. When assets are sold, or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and any gain or loss is included in operating expense.

Costs incurred to develop internal-use software during the application development stage are recorded as computer software costs, at cost. Costs incurred in the development of such internal-use software, including external direct costs of materials and services and applicable compensation costs of employees devoted to specific software application development, are capitalized. Costs incurred outside of the application development stage are expensed as incurred.

The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years

Leases

We lease approximately 2.8 million square feet of office, lab, manufacturing, and distribution facilities under various non-cancellable operating lease agreements (real estate leases). Our real estate leases have remaining lease terms of approximately 1 year to 15 years, which represent the non-cancellable periods of the leases and include extension options that we determined are reasonably certain to be exercised. We exclude extension options that are not reasonably certain to be exercised from our lease terms, ranging from approximately 2 years to 20 years. Our lease payments consist primarily of fixed rental payments for the right to use the underlying leased assets over the lease terms, as well as payments for common-area-maintenance and administrative services. We often receive customary incentives from our landlords, such as reimbursements for tenant improvements and rent abatement periods, which effectively reduce the total lease payments owed for these leases. Leases are classified as operating or financing at commencement. We do not have any material financing leases.

Operating lease right-of-use assets and liabilities on our consolidated balance sheets represent the present value of our remaining lease payments over the remaining lease terms, less any impairments recorded for right-of-use assets. We do not allocate lease payments to non-lease components; therefore, fixed payments for common-area-maintenance and administrative services are included in our operating lease right-of-use assets and liabilities. We use our incremental borrowing rate to calculate the present value of our lease payments, as the implicit rates in our leases are not readily determinable. Operating lease costs consist primarily of the fixed lease payments included in our operating lease liabilities and are recorded on a straight-line basis over the lease terms. We sublease certain real estate to third parties and this sublease income is also recorded on a straight-line basis.

Business Combinations

Under the acquisition method of accounting, we allocate the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. These valuations require us to make estimates and assumptions, especially with respect to intangible assets. We record the excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, as goodwill. Costs that we incur to complete the business combination, such as legal and other professional fees, are expensed as they are incurred.
In connection with certain acquisitions, contingent consideration can be earned by the sellers upon completion of certain future performance milestones. In these cases, a liability is recorded on the acquisition date, as a component of accrued liabilities and/or other long-term liabilities, for an estimate of the acquisition-date fair value of the contingent consideration. These estimates require management judgment, including probabilities of achieving certain future milestones. Changes in the fair value of the contingent consideration subsequent to the acquisition date are recognized in selling, general and administrative expense in our consolidated statements of operations.

If the initial accounting for a business combination is incomplete by the end of a reporting period that falls within the measurement period (not to exceed a year from the date of acquisition), we report provisional amounts in our financial statements. During the measurement period, we adjust the provisional amounts recognized at the acquisition date to reflect new information obtained about facts and circumstances that existed as of the acquisition date that, if known, would have affected the measurement of the amounts recognized as of that date. We record these adjustments to the provisional amounts with a corresponding offset to goodwill. Any adjustments identified after the measurement period are recorded in the consolidated statements of operations.

Goodwill, Intangible Assets and Other Long-Lived Assets

Assets acquired, including intangible assets and capitalized in-process research and development (IPR&D), and liabilities assumed are measured at fair value as of the acquisition date. Goodwill, which has an indefinite useful life, represents the excess of cost over fair value of the net assets acquired. Intangible assets acquired in a business combination that are used for IPR&D activities are considered indefinite lived until the completion or abandonment of the associated research and development efforts. Upon reaching the end of the relevant research and development project (i.e., upon commercialization), the IPR&D asset is amortized over its estimated useful life. If the relevant research and development project is abandoned, the IPR&D asset is expensed in the period of abandonment.

Goodwill and IPR&D are not amortized; however, they are reviewed for impairment at least annually during the second quarter, or more frequently if an event occurs indicating the potential for impairment. Goodwill and IPR&D are considered to be impaired if the carrying value of the reporting unit or IPR&D asset exceeds its respective fair value.

We perform our goodwill impairment analysis at the reporting unit level, which aligns with our reporting structure and availability of discrete financial information. During the goodwill impairment review, we assess qualitative factors to determine whether it is more likely than not that the fair values of our reporting units are less than the carrying amounts, including goodwill. The qualitative factors include, but are not limited to, macroeconomic conditions, industry and market considerations, and our overall financial performance. If, after assessing the totality of these qualitative factors, we determine that it is not more likely than not that the fair values of our reporting units are less than the carrying amounts, then no additional assessment is deemed necessary. Otherwise, we proceed to compare the estimated fair values of the reporting units with the carrying values, including goodwill. If the carrying amount of a reporting unit exceeds its fair value, we record an impairment loss based on the difference. We may elect to bypass the qualitative assessment in a period and proceed to perform the quantitative goodwill impairment test.

The IPR&D impairment test is performed by comparing the fair value of the asset to its carrying amount. When testing indefinite-lived intangibles for impairment, we may assess qualitative factors to determine whether it is more likely than not that the asset is impaired. Alternatively, we may bypass this qualitative assessment and perform a quantitative impairment test. If the IPR&D asset is impaired, the carrying value of the IPR&D is written down to the revised fair value with the related impairment charge recognized in the period in which the impairment occurs.

Our identifiable intangible assets with a finite life are typically comprised of acquired developed technologies, licensed technologies, customer relationships, license agreements, and trade names. The cost of identifiable intangible assets with finite lives is generally amortized on a straight-line basis over the assets’ respective estimated useful lives.

We perform regular reviews to determine if any event has occurred that may indicate that intangible assets with finite useful lives and other long-lived assets are potentially impaired. If indicators of impairment exist, an impairment test is performed to assess the recoverability of the affected assets by determining whether the carrying amount of such assets exceeds the undiscounted expected future cash flows. If the affected assets are not recoverable, we estimate the fair value of the assets and record an impairment loss in an amount equal to the excess of the carrying value over the fair value. Factors that may indicate potential impairment include a significant decline in our stock price and market capitalization compared to the net book value, significant changes in the ability of a particular asset to generate positive cash flows for our strategic business objectives, and the pattern of utilization of a particular asset.
We review our operating lease right-of-use (ROU) assets for impairment whenever events or changes in circumstances indicate the carrying value of the ROU asset may not be recoverable. The evaluation is performed at the lowest level for which identifiable cash flows are largely independent of the cash flows of other groups of assets and liabilities. We consider a triggering event to reassess an ROU asset’s asset group to have occurred if we exit a portion of or the full facility or enter into a sublease. Factors that may indicate potential impairment include a significant decrease in the market price of an underlying leased asset group. If we conclude the carrying value of affected assets will not be recovered, we estimate the fair value of the assets and record an impairment in an amount equal to the excess of the carrying value over the fair value.

Derivative Financial Instruments

We are exposed to foreign exchange rate risks in the normal course of business and use derivative financial instruments to partially offset this exposure. We do not use derivative financial instruments for speculative or trading purposes. Foreign exchange contracts are carried at fair value in other current assets, other assets, accrued liabilities, or other long-term liabilities, as appropriate, on the consolidated balance sheets.

We use foreign exchange forward contracts to manage foreign currency risks related to monetary assets and liabilities denominated in currencies other than the U.S. dollar. These derivative financial instruments have terms of one month or less and are not designated as hedging instruments. Changes in fair value of these derivatives are recognized in other (expense) income, net, along with the re-measurement gain or loss on the foreign currency denominated assets or liabilities. As of December 31, 2023, we had foreign exchange forward contracts in place to hedge exposures to monetary assets and liabilities denominated in the euro, Japanese yen, Australian dollar, Canadian dollar, Singapore dollar, Chinese Yuan Renminbi, and British pound. As of December 31, 2023 and January 1, 2023, the total notional amounts of outstanding forward contracts in place for these foreign currency purchases were $926 million and $485 million, respectively. In July 2023, we entered into forward contracts for a total notional amount of €432 million to hedge the foreign currency exposure for the fine imposed by the European Commission on July 12, 2023.

We also use foreign currency forward contracts to hedge portions of our foreign currency exposure associated with forecasted revenue transactions. These derivative financial instruments have terms up to 24 months and are designated as cash flow hedges. Changes in fair value of our cash flow hedges are recorded as a component of accumulated other comprehensive income and are reclassified to revenue in the same period the underlying hedged transactions are recorded. We regularly review the effectiveness of our cash flow hedges and consider them to be ineffective if it becomes probable that the forecasted transactions will not occur in the identified period. Changes in fair value of the ineffective portions of our cash flow hedges, if any, are recognized in other (expense) income, net. As of December 31, 2023, we had foreign currency forward contracts in place to hedge exposures associated with forecasted revenue transactions denominated in the euro, Japanese yen, Australian dollar, Canadian dollar, and Chinese Yuan Renminbi. As of December 31, 2023 and January 1, 2023, the total notional amounts of outstanding cash flow hedge contracts in place for these foreign currency purchases were $628 million and $425 million, respectively. We reclassified $18 million, $53 million, and $10 million to revenue in 2023, 2022, and 2021, respectively. As of December 31, 2023, the fair value of the foreign currency forward contracts recorded in total assets and total liabilities was $5 million and $9 million, respectively. As of January 1, 2023, the fair value of foreign currency forward contracts recorded in total assets and total liabilities was $8 million and $6 million, respectively.

Warranties

We generally provide a one-year warranty on instruments. Additionally, we provide a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, an accrual is established for estimated warranty expenses based on historical experience as well as anticipated product performance. We periodically review the warranty reserve for adequacy and adjust the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.

Share-Based Compensation

Share-based compensation expense is incurred related to restricted stock, cash-based equity incentive awards, Employee Stock Purchase Plan (ESPP), and stock options. Forfeitures are accounted for, as incurred, as a reversal of share-based compensation expense related to awards that will not vest.
Restricted stock units (RSU) and performance stock units (PSU) are both considered restricted stock. The determination of the amount of share-based compensation expense for our PSU requires the use of certain estimates and assumptions that affect the amount of share-based compensation expense recognized in our consolidated statements of operations. The fair value of restricted stock and performance stock units that do not include a market condition is determined by the closing market price of our common stock on the date of grant. PSU that do not include a market condition represent a right to receive a certain number of shares of common stock based on the achievement of corporate performance goals and continued employment during the vesting period. At each reporting period, we reassess the probability of the achievement of such corporate performance goals and any increase or decrease in share-based compensation expense resulting from an adjustment in the estimated shares to be released is treated as a cumulative catch-up in the period of adjustment. The fair value of performance stock units that include a market condition is determined on the date of grant using a Monte Carlo simulation, which includes assumptions for expected volatility, risk-free interest rate and divided yield. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Share-based compensation expense is recognized based on the fair value on a straight-line basis over the requisite service periods of the awards. Compensation expense for PSU that include a market condition is recognized over the requisite service period regardless of whether the market conditions are achieved.

Cash-based equity incentive awards are classified as liability awards, as such awards will be settled in cash. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, is used. The fair value of the awards is recorded over the respective vesting periods of the awards, with recognition of a corresponding liability recorded in accrued liabilities in the consolidated balance sheets. The awards are remeasured to fair value at each reporting date until the awards are settled, with changes in fair value recognized in share-based compensation expense.

The Black-Scholes-Merton option-pricing model is used to estimate the fair value of stock purchased under our ESPP and stock options granted. The model assumptions include expected volatility, term, dividends, and the risk-free interest rate. The expected volatility is generally determined by weighing the historical and implied volatility of our common stock. The historical volatility is generally commensurate with the estimated expected term. The implied volatility is calculated from the implied market volatility of exchange-traded call options on our common stock. The expected term is generally based on historical forfeiture experience, exercise activity, and on the terms and conditions of the stock awards. The expected dividend yield is determined to be 0% given that we have never declared or paid cash dividends on our common stock and do not anticipate paying such cash dividends. The risk-free interest rate is based upon U.S. Treasury securities with remaining terms similar to the expected term of the share-based awards.

Shipping and Handling Expenses

Shipping and handling expenses are included in cost of product revenue.

Research and Development

Research and development expenses include personnel expenses, contractor fees, facilities-related costs, material costs, and license fees. Expenditures relating to research and development are expensed in the period incurred.
Advertising Costs

Advertising costs are expensed as incurred. Advertising costs were $36 million, $53 million, and $48 million in 2023, 2022, and 2021, respectively.

Restructuring

We measure and accrue liabilities associated with employee separation costs, which primarily consist of severance pay and other separation costs such as outplacement services and benefits, at fair value as of the date the plan is approved and when such costs are reasonably estimable. The fair value measurement of restructuring related liabilities requires certain assumptions and estimates to be made, such as the retention period of certain employees. It is our policy to use the best estimates based on facts and circumstances available at the time of measurement, review the assumptions and estimates periodically, and adjust the liabilities when necessary.

Income Taxes

The provision for income taxes is computed using the asset and liability method, under which deferred tax assets and liabilities are recognized for the expected future tax consequences of temporary differences between the financial reporting and tax bases of assets and liabilities, and for the expected future tax benefit to be derived from tax loss and credit carryforwards. Deferred tax assets and liabilities are determined using the enacted tax rates in effect for the years in which those tax assets are expected to be realized. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in the provision for income taxes in the period that includes the enactment date.

Deferred tax assets are regularly assessed to determine the likelihood they will be recovered from future taxable income. A valuation allowance is established when we believe it is more likely than not the future realization of all or some of a deferred tax asset will not be achieved. In evaluating the ability to recover deferred tax assets within the jurisdiction which they arise, we consider all available positive and negative evidence. Factors reviewed include the cumulative pre-tax book income for the past three years, scheduled reversals of deferred tax liabilities, history of earnings and reliable forecasting, projections of pre-tax book income over the foreseeable future, and the impact of any feasible and prudent tax planning strategies.
The impact of a tax position is recognized in the consolidated financial statements only if that position is more likely than not of being sustained upon examination by taxing authorities, based on the technical merits of the position. Any interest and penalties related to uncertain tax positions will be reflected in income tax expense.
v3.24.0.1
Revenue
12 Months Ended
Dec. 31, 2023
Revenue from Contract with Customer [Abstract]  
Revenue
2. REVENUE
Our revenue is generated from the sale of products and services. Product revenue consists of sales of instruments and consumables used in genetic analysis. Service and other revenue consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and cancer detection testing services related to the GRAIL business.

Revenue by Source
202320222021
In millionsSequencingMicroarrayTotalSequencingMicroarrayTotalSequencingMicroarrayTotal
Consumables$2,790 $293 $3,083 $2,919 $306 $3,225 $2,911 $306 $3,217 
Instruments685 19 704 709 19 728 734 17 751 
Total product revenue3,475 312 3,787 3,628 325 3,953 3,645 323 3,968 
Service and other revenue637 80 717 543 88 631 464 94 558 
Total revenue$4,112 $392 $4,504 $4,171 $413 $4,584 $4,109 $417 $4,526 
Revenue by Geographic Area

Based on region of destination (in millions)2023
2022 (1)
2021 (1)
Americas (2)
$2,521 $2,479 $2,358 
Europe1,140 1,089 1,149 
Greater China (3)
384 472 502 
Asia-Pacific, Middle East and Africa (4)
459 544 517 
Total revenue$4,504 $4,584 $4,526 
_____________
(1)We implemented a new global commercial structure in Q1 2023 to improve operating efficiencies and better align with local markets. We integrated Asia-Pacific and Japan with emerging markets across the Middle East, Africa, Turkey, and Commonwealth of Independent States (CIS). Beginning in Q1 2023, and going forward, we will report regional results for the following regions: Americas, Europe, Greater China, and Asia-Pacific, Middle East and Africa (AMEA). Prior period amounts have been reclassified to conform to this new presentation.
(2)Americas revenue included United States revenue of $2,359 million, $2,290 million, and $2,195 million in 2023, 2022, and 2021, respectively.
(3)Region includes revenue from China, Taiwan, and Hong Kong.
(4)Region includes revenue from Russia and Turkey.

Performance Obligations

We regularly enter into contracts with multiple performance obligations. These contracts are believed to be firm as of the balance sheet date. However, we may allow customers to make product substitutions as we launch new products. The timing of shipments depends on several factors, including agreed upon shipping schedules, which may span multiple quarters. Most performance obligations are generally satisfied within a short time frame, approximately three to six months, after the contract execution date. As of December 31, 2023, the aggregate amount of the transaction price allocated to remaining performance obligations was $653 million, of which approximately 82% is expected to be converted to revenue in 2024, approximately 13% in the following twelve months, and the remainder thereafter.

Contract Assets and Liabilities

Contract assets, which consist of revenue recognized and performance obligations satisfied or partially satisfied in advance of customer billing, as of December 31, 2023 and January 1, 2023 were $18 million and $17 million, respectively, all of which were short-term and recorded in prepaid expenses and other current assets.
Contract liabilities, which consist of deferred revenue and customer deposits, as of December 31, 2023 and January 1, 2023 were $329 million and $308 million, respectively, of which the short-term portions of $252 million and $245 million, respectively, were recorded in accrued liabilities and the remaining long-term portions were recorded in other long-term liabilities. Revenue recorded in 2023 included $235 million of previously deferred revenue that was included in contract liabilities as of January 1, 2023.
v3.24.0.1
Investments and Fair Value Measurements
12 Months Ended
Dec. 31, 2023
Fair Value Disclosures [Abstract]  
Investments and Fair Value Measurements
3. INVESTMENTS AND FAIR VALUE MEASUREMENTS
Strategic Investments

Marketable Equity Securities

Our short-term investments consist of marketable equity securities. As of December 31, 2023 and January 1, 2023, the fair value of our marketable equity securities totaled $6 million and $26 million, respectively.

Gains and losses recognized in other (expense) income, net on our marketable equity securities were as follows:
In millions202320222021
Net (losses) recognized during the period on marketable equity securities$(2)$(81)$(52)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period(2)— (89)
Net unrealized (losses) gains recognized during the period on marketable equity securities still held at the reporting date$ $(81)$37 

Non-Marketable Equity Securities

As of both December 31, 2023 and January 1, 2023, the aggregate carrying amounts of our non-marketable equity securities without readily determinable fair values, included in other assets, were $28 million.

Revenue recognized from transactions with our strategic investees was $69 million, $113 million, and $74 million in 2023, 2022, and 2021, respectively.

Venture Funds

We invest in two venture capital investment funds (the Funds) with capital commitments of $100 million, callable through April 2026, and up to $150 million, callable through July 2029, respectively, of which $4 million and up to $71 million, respectively, remained callable as of December 31, 2023. Our investments in the Funds are accounted for as equity-method investments. The aggregate carrying amounts of the Funds, included in other assets, were $168 million and $183 million as of December 31, 2023 and January 1, 2023, respectively. We recorded net unrealized losses of $33 million and $25 million in 2023 and 2022, respectively, and a net unrealized gain of $55 million in 2021, in other (expense) income, net.
Fair Value Measurements

The following table presents the hierarchy for assets and liabilities measured at fair value on a recurring basis:

December 31, 2023January 1, 2023
In millionsLevel 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets:
Money market funds (cash equivalents)$774 $ $ $774 $1,642 $— $— $1,642 
Marketable equity securities6   6 26 — — 26 
Helix contingent value right  68 68 — — 58 58 
Deferred compensation plan assets 61  61 — 52 — 52 
Total assets measured at fair value$780 $61 $68 $909 $1,668 $52 $58 $1,778 
Liabilities:
Contingent consideration liabilities$ $ $387 $387 $— $— $412 $412 
Deferred compensation plan liability 59  59 — 51 — 51 
Total liabilities measured at fair value$ $59 $387 $446 $— $51 $412 $463 

Our marketable equity securities are measured at fair value based on quoted trade prices in active markets.

Our deferred compensation plan assets consist primarily of investments in life insurance contracts carried at cash surrender value, which reflects the net asset value of the underlying publicly traded mutual funds. We perform control procedures to corroborate the fair value of our holdings, including comparing valuations obtained from our investment service provider to valuations reported by our asset custodians, validating pricing sources and models, and reviewing key model inputs, if necessary.

Helix Contingent Value Right

In conjunction with the deconsolidation of Helix Holdings I, LLC (Helix) in April 2019, we received a contingent value right with a 7-year term that entitles us to consideration dependent upon the outcome of Helix’s future financing and/or liquidity events. We elected the fair value option to measure the contingent value right received from Helix. The fair value of the contingent value right, included in other assets, is derived using a Monte Carlo simulation. Estimates and assumptions used in the Monte Carlo simulation include probabilities related to the timing and outcome of future financing and/or liquidity events, assumptions regarding collectability and volatility, and an estimated equity value of Helix. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value.

Changes in the fair value of the Helix contingent value right, included in other (expense) income, net were as follows:

In millions
Balance as of January 3, 2021$35 
Change in estimated fair value30 
Balance as of January 2, 202265 
Change in estimated fair value(7)
Balance as of January 1, 202358 
Change in estimated fair value10 
Balance as of December 31, 2023$68 
Contingent Consideration Liabilities
We reassess the fair value of contingent consideration related to acquisitions on a quarterly basis. Changes in the fair value of contingent consideration subsequent to the acquisition date are recognized in selling, general and administrative expense. The contingent value rights issued as part of the GRAIL acquisition entitle the holders to receive future cash payments on a quarterly basis (Covered Revenue Payments) representing a pro rata portion of certain GRAIL-related revenues (Covered Revenues) each year for a 12-year period. As defined in the Contingent Value Rights Agreement, this will reflect a 2.5% payment right to the first $1 billion of revenue each year for 12 years. Revenue above $1 billion each year will be subject to a 9% contingent payment right during this same period. Covered Revenues for the period Q4 2022 through Q3 2023 were $85 million in aggregate and Covered Revenues for the period Q4 2021 through Q3 2022 were $42 million in aggregate, driven primarily by sales of GRAIL’s Galleri test. Covered Revenue Payments relating to such periods were approximately $803,000 and $396,000 in 2023 and 2022, respectively. Pursuant to the Contingent Value Rights Agreement, a portion of the Covered Revenue Payments in 2022 were applied to reimburse us for certain expenses. We use a Monte Carlo simulation to estimate the fair value of contingent consideration related to the GRAIL acquisition. Estimates and assumptions used in the Monte Carlo simulation include forecasted revenues for GRAIL, a revenue risk premium, a revenue volatility estimate, an operational leverage ratio and a counterparty credit spread. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. The fair value of our contingent consideration liability related to GRAIL was $387 million and $412 million as of December 31, 2023 and January 1, 2023, respectively, of which $385 million and $411 million, respectively, was included in other long-term liabilities, with the remaining balances included in accrued liabilities.

Changes in the estimated fair value of our contingent consideration liabilities were as follows:

In millions
Balance as of January 3, 2021$— 
Acquisition of GRAIL762 
Other acquisition14 
Measurement period adjustment related to GRAIL acquisition(5)
Cash payments(15)
Exchange of GRAIL contingent value rights(145)
Change in estimated fair value
Balance as of January 2, 2022615 
Acquisition
Change in estimated fair value(205)
Balance as of January 1, 2023412 
Change in estimated fair value(24)
Cash payments(1)
Balance as of December 31, 2023$387 

In December 2021, we exchanged approximately 73 million contingent value rights, that were issued as part of the GRAIL acquisition, for an aggregate cash payment of $57 million and the issuance of $2 million in shares of our common stock. As a result of the exchange, we recognized a gain of $86 million in other (expense) income, net in 2021, which represented the difference between the fair value of the contingent consideration liability for the contingent value rights exchanged of $145 million and the total consideration transferred of $59 million.
We recorded a contingent consideration liability of $14 million as a result of an acquisition completed in Q2 2021. The acquisition-date fair value of the contingent consideration was derived using the income approach. Assumptions used to estimate the liability included the probability of achieving certain milestones and a discount rate. These unobservable inputs represented a Level 3 measurement because they were supported by little or no market activity and reflected our own assumptions in measuring fair value. We recorded an expense of $1 million in selling, general and administrative expense in 2021 due to the change in estimated fair value of the contingent consideration and made a payment of $15 million in Q4 2021 upon achievement of the milestones.
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets
12 Months Ended
Dec. 31, 2023
Business Combination And Goodwill And Intangible Assets [Abstract]  
Acquisitions, Goodwill and Intangible Assets
4. ACQUISITIONS, GOODWILL AND INTANGIBLE ASSETS
Acquisition of GRAIL, Inc.

On August 18, 2021, we completed our acquisition of GRAIL, a healthcare company focused on early detection of multiple cancers. The acquisition is subject to ongoing legal proceedings and, currently, GRAIL must be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission in the EC Divestment Decision, following the prohibition of our acquisition of GRAIL on September 6, 2022. Refer to note “8. Legal Proceedings” for further details. As a result of the acquisition, GRAIL stockholders received as consideration (i) cash, (ii) shares of Illumina common stock and (iii) at their election, either a contingent value right or additional shares of Illumina common stock. We issued 9.8 million common shares as part of the consideration. GRAIL is a separate reportable segment. We have included the financial results of GRAIL in the consolidated financial statements from the date of acquisition. On December 17, 2023, we announced that we will divest GRAIL.

The total purchase price consisted of the following:

In millionsAs Adjusted
Cash$2,862 
Fair value of common stock issued4,975 
Fair value of contingent consideration757 
Fair value of previously held investment1,149 
Settlement of preexisting relationships
Total purchase price$9,745 

Prior to the acquisition, we owned a 12% interest in GRAIL. Authoritative guidance on accounting for business combinations requires that an acquirer remeasure its previously held equity investment in the acquiree at its acquisition-date fair value and recognize the resulting gain or loss in earnings. We remeasured our previously held equity investment to its fair value, as of the date of acquisition, based on the fair value of total consideration transferred and a discount for lack of control. Estimates and assumptions used in the remeasurement represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring the fair value. As a result of the remeasurement, we valued our previously held equity investment in GRAIL at $1.1 billion and recognized a gain of $899 million, included in other (expense) income, net, in 2021.

In connection with the acquisition, we accelerated the vesting of certain outstanding and unvested equity awards of GRAIL employees. Approximately $69 million was included in the purchase price related to the fair value of accelerated equity awards attributable to the pre-combination period, with the fair value attributable to the post-combination period of $615 million included in share-based compensation expense in 2021. In addition, we issued Illumina equity awards to GRAIL employees in exchange for any of their remaining outstanding and unvested GRAIL equity awards (the “replacement awards”) at acquisition. The replacement awards consist of restricted stock units and performance stock options. The terms of the replacement awards are substantially similar to the former GRAIL equity awards for which they were exchanged. The fair value of the replacement awards was $48 million, all of which is attributable to post-combination service, and will be recognized as share-based compensation expense over the remaining vesting period subsequent to the acquisition. The weighted-average acquisition-date fair value of the replacement performance stock options was determined using the Black-Scholes option pricing model. Refer to note “6. Stockholders’ Equity” for more information.
We finalized the allocation of the purchase price in August 2022. The fair values of assets acquired and liabilities assumed were:
In millionsAs Initially ReportedMeasurement Period AdjustmentsAs Adjusted
Cash and cash equivalents$571 $— $571 
Property and equipment89 — 89 
Operating lease right-of-use assets121 — 121 
Goodwill6,082 6,091 
Intangible assets3,180 (60)3,120 
Other current and noncurrent assets35 — 35 
Deferred tax liability(82)46 (36)
Long-term lease liabilities(97)— (97)
Other current and noncurrent liabilities(148)(1)(149)
Total net assets acquired$9,751 $(6)$9,745 

We recorded a measurement period adjustment in Q3 2022 to decrease goodwill and increase deferred tax assets by $6 million, as a result of finalizing GRAIL’s U.S. tax returns. In Q4 2021, we recorded measurement period adjustments to decrease intangible assets, specifically, developed technology, as a result of revised future cash flow estimates and to decrease deferred tax liability as a result of changes in net operating loss estimates from the initial purchase price allocation. These measurement period adjustments were made to reflect facts and circumstances that existed as of the acquisition date. The measurement period adjustment related to the developed technology intangible asset would have resulted in an insignificant decrease in amortization expense recorded in Q3 2021. The measurement period adjustments were recorded in our consolidated financial statements as of and for the years ended 2022 and 2021, as appropriate. The goodwill recognized was assigned to the GRAIL segment.

The fair values assigned to identifiable intangible assets acquired were as follows:

In millions, except yearsFair Value
(as adjusted)
Estimated Useful Life
Developed technology$2,410 18
Trade name40 9
In-process research and development (IPR&D)670 Indefinite
Total intangible assets$3,120 

The fair values of the developed technology, trade name and IPR&D were estimated using an income approach. Under the income approach, an intangible asset’s fair value is equal to the present value of future economic benefits to be derived from ownership of the asset. The estimated fair values were developed by discounting future net cash flows to their present value at market-based rates of return and inclusive of an assumption for technology obsolescence. The useful lives of the intangible assets for amortization purposes were determined by considering the period of expected cash flows used to measure the fair values of the intangible assets adjusted as appropriate for entity-specific factors including legal, regulatory, contractual, competitive, economic and other factors that may limit the useful life. The developed technology and trade name assets are amortized on a straight-line basis over their estimated useful lives. As of December 31, 2023, the research and development project had not been completed or abandoned and, therefore, the IPR&D intangible asset is not currently subject to amortization.

The transaction costs associated with the acquisition of GRAIL, excluding any Continuation Payments paid to GRAIL prior to the close of the acquisition, consisted primarily of legal, regulatory and financial advisory fees of approximately $156 million, which were expensed as incurred as selling, general and administrative expense in 2021.

Prior to the acquisition, we were required to make monthly cash payments to GRAIL of $35 million (the Continuation Payments) through the earlier of the consummation of the acquisition or termination of the GRAIL Merger Agreement, subject to certain exceptions. We made Continuation Payments to GRAIL totaling $245 million in 2021, which were
recorded as selling, general and administrative expense. Subsequent to the acquisition, we did not make any additional Continuation Payments.

Goodwill
In millions
Balance as of January 2, 2022$7,113 
Impairment(3,914)
Acquisition45 
Measurement period adjustments(5)
Balance as of January 1, 20233,239 
Impairment(712)
Acquisition18 
Balance as of December 31, 2023$2,545 
2023 Impairment of Goodwill

We test goodwill for impairment annually, as of May, or more frequently if events or circumstances indicate it is more likely than not that the fair value of a reporting unit is less than its carrying amount. We performed our annual impairment test in Q2 2023, as of May 2023. We performed a quantitative assessment for our two reporting units: Core Illumina and GRAIL. No impairment was recorded for either Core Illumina or GRAIL in Q2 2023.

In Q3 2023, we concluded the sustained decrease in the Company’s stock price and overall market capitalization during the quarter was a triggering event indicating the fair value of a reporting unit might be less than its carrying amount and that an interim goodwill and intangible impairment test was required.

Based on our interim assessment, we concluded that our GRAIL reporting unit’s carrying value exceeded its estimated fair value. As a result, we recorded $712 million of goodwill impairment related to our GRAIL reporting unit in Q3 2023, primarily due to a decrease in the company’s consolidated market capitalization and a higher discount rate selected for the fair value calculation of the GRAIL reporting unit. No impairment was recorded for our Core Illumina reporting unit, noting its fair value exceeded its carrying value.

We performed our impairment test using a combination of an income and a market approach to determine the fair value of each reporting unit. The income approach utilized the estimated discounted cash flows for each reporting unit, while the market approach utilized comparable company information. Estimates and assumptions used in the income approach included projected cash flows and a discount rate for each reporting unit. Discount rates were determined using a weighted average cost of capital for risk factors specific to each reporting unit and other market and industry data. For GRAIL, the selected discount rate was 24.0%. The estimates and assumptions used in our assessment represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. The assumptions used are inherently subject to uncertainty and we note that small changes in these assumptions could have a significant impact on the concluded value. In order to further validate the reasonableness of the fair values concluded for our reporting units, a reconciliation to market capitalization was performed by estimating a reasonable implied control premium and other market factors.

In conjunction with the Q3 2023 interim goodwill impairment test, we also evaluated the in-process research and development (IPR&D) asset assigned to the GRAIL reporting unit for potential impairment. We performed our impairment test by comparing the carrying value of the IPR&D asset to its estimated fair value, which was determined by the income approach, using a discounted cash flow model. Estimates and assumptions used in the income approach, which represent a Level 3 measurement, included projected cash flows and a selected discount rate of 19.0%. Based on our Q3 2023 impairment test, the carrying value of the GRAIL IPR&D asset exceeded its estimated fair value and we recorded an impairment of $109 million in Q3 2023, primarily due to a decrease in projected cash flows and a higher discount rate selected for the fair value calculation of the GRAIL IPR&D asset. As of December 31, 2023, the carrying value of the GRAIL IPR&D asset was $561 million. We also performed a recoverability test for the definite-lived intangible assets assigned to GRAIL, which includes developed technology and trade name, noting no impairment. No impairment was noted for Core Illumina definite-lived intangible assets.
In Q4 2023, we concluded, among other events, that our formal announcement, in December 2023, to divest GRAIL represented a triggering event that required an additional interim goodwill and intangible impairment test be performed. As a result of the assessment, no impairment was recorded for either Core Illumina or GRAIL in Q4 2023. The fair values of GRAIL and Core Illumina exceeded their carrying values by approximately $950 million and $19 billion, respectively. For GRAIL, the selected discount rate used in the Q4 2023 impairment test was 23%. An increase of 100 basis points to the selected discount rate would still have resulted in no impairment for the GRAIL segment. As of December 31, 2023, remaining goodwill allocated to GRAIL was $1,466 million. Changes in our future operating results, cash flows, share price, market capitalization or discount rates used when conducting future goodwill impairment tests could affect the estimated fair values of our reporting units and may result in additional impairment charges in the future. We will continue to monitor events and circumstances which may suggest that interim impairment indicators are present prior to our next annual impairment test. We also performed a recoverability test for the definite-lived intangible assets assigned to GRAIL in Q4 2023, noting no impairment. Additionally, no impairment was noted for Core Illumina definite-lived intangible assets.
2022 Impairment of Goodwill
On July 13, 2022, the EU General Court ruled that the European Commission has jurisdiction under the EU Merger Regulation to review our acquisition of GRAIL. Additionally, on September 6, 2022, the European Commission issued its decision prohibiting the acquisition. Refer to note “8. Legal Proceedings” for additional details. These decisions, along with a continued and significant decrease in the Company’s stock price and market capitalization, required us to perform an interim goodwill and intangible asset impairment test in Q3 2022.

Based on our interim analysis, we concluded that our GRAIL reporting unit’s carrying value exceeded its estimated fair value. As a result, we recorded $3,914 million of goodwill impairment related to our GRAIL reporting unit in Q3 2022, primarily due to the negative impact of current capital market conditions and a higher discount rate selected for the fair value calculation of the GRAIL reporting unit. No impairment was recorded for our Core Illumina reporting unit, noting its fair value exceeded its carrying value by more than $30 billion.
We performed our interim goodwill impairment test using a combination of both an income and a market approach to determine the fair value of each reporting unit. The income approach utilized the estimated discounted cash flows for each reporting unit while the market approach utilized comparable company information. Estimates and assumptions used in the income approach included projected cash flows for both the GRAIL and Core Illumina reporting units and a discount rate for each reporting unit. Discount rates were determined using a weighted average cost of capital for risk factors specific to each reporting unit and other market and industry data. For the GRAIL reporting unit, the discount rate selected was 22.0%. The estimates and assumptions used in our assessment represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. In order to further validate the reasonableness of the fair values concluded for our reporting units, a reconciliation to market capitalization was performed by estimating a reasonable implied control premium and other market factors.
In conjunction with the interim goodwill impairment test in Q3 2022, we also evaluated the IPR&D intangible asset, assigned to the GRAIL reporting unit, for potential impairment. We performed our interim impairment test by comparing the carrying value of the IPR&D intangible asset to its estimated fair value, which was determined by the income approach, using a discounted cash flow model. Estimates and assumptions used in the income approach included projected cash flows and a discount rate. These estimates and assumptions represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Based on our interim impairment test, the carrying value of the IPR&D intangible asset did not exceed its estimated fair value. As a result, no impairment for the IPR&D intangible asset was recorded. We also performed a recoverability test for the definite-lived intangible assets assigned to the GRAIL reporting unit, which includes developed technology and trade name, noting no impairment. Additionally, no impairment was noted for the definite-lived intangible assets assigned to our Core Illumina reporting unit.
Intangible Assets
 December 31, 2023January 1, 2023
In millionsGross
Carrying
Amount
Accumulated
Amortization
ImpairmentIntangible Assets,
Net
Gross
Carrying
Amount
Accumulated
Amortization
Intangible Assets,
Net
Developed technologies$2,807 $(585)$ $2,222 $2,812 $(449)$2,363 
Licensed technologies274 (133) 141 274 (105)169 
Trade name43 (14) 29 44 (10)34 
Customer relationships14 (13) 1 31 (29)
License agreements14 (13) 1 15 (14)
Database12 (3) 9 12 (1)11 
Total finite-lived intangible assets, net3,164 (761) 2,403 3,188 (608)2,580 
In-process research and development (IPR&D)705  (115)590 705 — 705 
Total intangible assets, net$3,869 $(761)$(115)$2,993 $3,893 $(608)$3,285 
As a result of an acquisition in Q4 2023, we recorded a developed technology intangible asset of $19 million, with a useful life of 10 years. We are still finalizing the allocation of the purchase price as additional information is received to complete our analysis. We expect to finalize the valuation as soon as practicable, but no later than one year after the acquisition date. As a result of an acquisition in Q2 2022, we recorded a developed technology intangible asset of $23 million, with a useful life of 7 years, and a database intangible asset of $12 million, with a useful life of 7 years. We finalized the allocation of the purchase price in Q2 2023, with no material adjustments to our preliminary purchase price allocation. In addition, we recorded a licensed technology intangible asset of $180 million, with a useful life of 6.5 years, as a result of our litigation settlement with BGI in Q3 2022. Refer to note “8. Legal Proceedings” for additional details.
As a result of an acquisition completed in Q2 2021, we recorded an IPR&D intangible asset of $35 million, with an indefinite useful life. As of December 31, 2023, the research and development project had not been completed or abandoned and, therefore, the IPR&D intangible asset is not currently subject to amortization. During Q4 2023, we evaluated the IPR&D intangible asset for potential impairment and recorded an impairment of $6 million.
The estimated future annual amortization of finite-lived intangible assets is shown in the following table. Actual amortization expense to be reported in future periods could differ from these estimates as a result of acquisitions, divestitures, and asset impairments, among other factors.
In millionsEstimated Annual Amortization
2024$197 
2025197 
2026185 
2027183 
2028180 
Thereafter1,461 
Total$2,403 
v3.24.0.1
Debt and Other Commitments
12 Months Ended
Dec. 31, 2023
Debt Disclosure [Abstract]  
Debt and Other Commitments
5. DEBT AND OTHER COMMITMENTS
Summary of Term Debt Obligations
In millionsDecember 31,
2023
January 1,
2023
Principal amount of 2031 Term Notes outstanding$500 $500 
Principal amount of 2027 Term Notes outstanding500 500 
Principal amount of 2025 Term Notes outstanding500 500 
Principal amount of 2023 Term Notes outstanding 500 
Unamortized discounts and debt issuance costs(11)(13)
Net carrying amount of term notes1,489 1,987 
Less: current portion (500)
Term notes, non-current$1,489 $1,487 
Fair value of term notes outstanding (Level 2)$1,440 $1,913 

Interest expense recognized on our term notes, which included amortization of debt discounts and issuance costs, was $74 million, $21 million and $14 million in 2023, 2022 and 2021, respectively.

0.550% Term Notes due 2023 (2023 Term Notes) and 2.550% Term Notes due 2031 (2031 Term Notes)

In March 2021, we issued $500 million aggregate principal amount of 2023 Term Notes and $500 million aggregate principal amount of 2031 Term Notes. We received net proceeds from the issuance of $992 million, after deducting discounts and debt issuance costs. The 2023 Term Notes matured and were repaid in cash on March 23, 2023.

The 2031 Term Notes, which mature on March 23, 2031, accrue interest at a rate of 2.550% per annum, payable semi-annually on March 23 and September 23 of each year, beginning on September 23, 2021. We may redeem for cash all or any portion of the 2031 Term Notes, at our option, at any time prior to maturity. Prior to December 23, 2030, the notes are redeemable at make-whole premium redemption prices as defined in the applicable forms of note. After December 23, 2030, the notes are redeemable at a redemption price equal to 100% of the principal amount of the notes to be redeemed, plus any accrued and unpaid interest up to, but excluding, the redemption date.

5.800% Term Notes due 2025 (2025 Term Notes) and 5.750% Term Notes due 2027 (2027 Term Notes)

In December 2022, we issued $500 million aggregate principal amount of 2025 Term Notes and $500 million aggregate principal amount of 2027 Term Notes. We received net proceeds from the issuance of $991 million, after deducting discounts and debt issuance costs. The 2025 Term Notes, which mature on December 12, 2025, and the 2027 Term Notes, which mature on December 13, 2027, accrue interest at a rate of 5.800% and 5.750% per annum, respectively, payable semi-annually. Interest for the 2025 Term Notes is payable on June 12 and December 12 of each year, beginning on June 12, 2023. Interest for the 2027 Term Notes is payable on June 13 and December 13 of each year, beginning on June 13, 2023.

We may redeem for cash all or any portion of the 2025 or 2027 Term Notes, at our option, at any time prior to maturity. Prior to November 12, 2025 for the 2025 Term Notes and prior to November 13, 2027 for the 2027 Term Notes, the notes are redeemable at make-whole premium redemption prices as defined in the applicable forms of note. After November 12, 2025 for the 2025 Term Notes and after November 13, 2027 for the 2027 Term Notes, the notes are redeemable at a redemption price equal to 100% of the principal amount of the notes to be redeemed, plus any accrued and unpaid interest up to, but excluding, the redemption date.

0% Convertible Senior Notes due 2023 (2023 Convertible Notes)

In August 2018, we issued $750 million aggregate principal amount of 2023 Convertible Notes. The notes were convertible into cash, shares of common stock or a combination of cash and shares of common stock, at our election, based on conversion rates as defined in the indenture. The 2023 Convertible Notes matured on August 15, 2023, at which time the principal was repaid in cash. We did not issue any shares of common stock.
The 2023 Convertible Notes were initially accounted for in accordance with authoritative guidance for convertible debt instruments that may be settled in cash upon conversion. The guidance required the carrying amount of the liability component to be estimated by estimating the fair value of a similar liability that does not have an associated conversion feature. Because at issuance we had no outstanding non-convertible public debt, we determined that market-traded senior, unsecured corporate bonds represented a similar liability without a conversion option. Based on market data available for publicly traded, senior, unsecured corporate bonds issued by companies in our industry, and with similar maturities to the 2023 Convertible Notes, we estimated an implied interest rate of 3.7%, assuming no conversion option. Assumptions used in the estimate represented what market participants would use in pricing the liability component, including market interest rates, credit standing, and yield curves, all of which are defined as Level 2 observable inputs. The estimated implied interest rate was applied to the 2023 Convertible Notes, which resulted in a fair value of the liability component in aggregate of $624 million upon issuance, calculated as the present value of implied future payments based on the $750 million aggregate principal amount. The $126 million difference ($93 million, net of tax) between the aggregate principal amount of $750 million and the estimated fair value of the liability component was recorded in additional paid-in capital as the 2023 Convertible Notes were not considered redeemable. As a policy election under applicable guidance related to the calculation of diluted (loss) earnings per share, we had elected the combination settlement method as our stated settlement policy and applied the treasury stock method in the calculation of the potential dilutive impact of the 2023 Convertible Notes on (loss) earnings per share each period.

As of January 3, 2022, we adopted ASU 2020-06, which removed the requirement to separate the embedded conversion feature from the notes and requires the notes to be accounted for as a single liability measured at amortized cost. Accordingly, we reclassified the unamortized debt discount from additional paid-in capital to convertible senior notes in the consolidated balance sheets on January 3, 2022. This resulted in an increase to our convertible senior notes and retained earnings of $43 million and $61 million, respectively, and a decrease to our deferred tax liabilities, included in other long-term liabilities, and additional paid-in capital of $11 million and $93 million, respectively.

Interest expense recognized on the 2023 Convertible Notes, which included amortization of debt issuance costs, was $2 million and $3 million in 2023 and 2022, respectively. Interest expense recognized on the 2023 Convertible Notes in 2021 was $29 million, which included amortization of the original debt discount and debt issuance costs.

Credit Agreement

On January 4, 2023, we entered into a new credit agreement (the Credit Agreement), which provides us with a $750 million senior unsecured five-year revolving credit facility, including a $40 million sublimit for swingline borrowings and a $50 million sublimit for letters of credit (the Credit Facility). The proceeds of the loans under the Credit Facility may be used to finance working capital needs and for general corporate purposes. The credit agreement dated as of March 8, 2021 and the commitments thereunder were terminated as of January 4, 2023.

The Credit Facility matures, and all amounts outstanding thereunder become due and payable in full, on January 4, 2028, subject to two one-year extensions at our option, the consent of the extending lenders and certain other conditions. We may prepay amounts borrowed and terminate commitments under the Credit Facility at any time without premium or penalty. As of December 31, 2023, there were no borrowings or letters of credit outstanding under the Credit Facility and we were in compliance with all financial and operating covenants.

Any loans under the Credit Facility will have a variable interest rate based on either the term secured overnight financing rate or the alternate base rate, plus an applicable rate that varies with the Company’s debt rating and, in the case of loans bearing interest based on the term secured overnight financing rate, a credit spread adjustment equal to 0.10% per annum. The Credit Agreement includes an option for us to elect to increase the commitments under the Credit Facility or to enter into one or more tranches of term loans in the aggregate principal amount of up to $250 million, subject to the consent of the lenders providing the additional commitments or term loans, as applicable, and certain other conditions.

The Credit Agreement contains financial and operating covenants. Pursuant to the Credit Agreement, we are required to maintain a ratio of total debt to adjusted annual earnings before interest, taxes, depreciation and amortization (EBITDA), calculated based on the four consecutive fiscal quarters ending with the most recent fiscal quarter, of not greater than 3.50 to 1.00 as of the end of each fiscal quarter. Upon the consummation of any Qualified Acquisition (as defined in the Credit Agreement) and us providing notice to the Administrative Agent, the ratio increases to 4.00 to
1.00 for the fiscal quarter in which the acquisition is consummated and the three consecutive fiscal quarters thereafter. The operating covenants include, among other things, limitations on (i) the incurrence of indebtedness by our subsidiaries, (ii) liens on our and our subsidiaries assets, and (iii) certain fundamental changes and the disposition of assets by us and our subsidiaries. The Credit Agreement contains other customary covenants, representations and warranties, and events of default.

Leases

As of December 31, 2023, the maturities of our operating lease liabilities were as follows:
In millions
2024$117
2025117
2026115
2027107
202889
Thereafter385
Total remaining lease payments (1)
930
Less: imputed interest(157)
Total operating lease liabilities773
Less: current portion(86)
Long-term operating lease liabilities$687
Weighted-average remaining lease term8.8 years
Weighted-average discount rate4.2 %
_____________
(1)Total remaining lease payments exclude $60 million of legally binding minimum lease payments for leases signed but not yet commenced.

The components of our lease costs were as follows:
In millions202320222021
Operating lease costs
$116 $112 $99 
Sublease income(20)(20)(16)
Variable lease costs (1)
27 20 21 
Total lease costs$123 $112 $104 
_____________
(1)Variable lease costs include non-fixed maintenance charges and property taxes.

Purchase Obligations

In the normal course of business, we enter into agreements to purchase goods or services that are not cancelable without penalty, primarily related to licensing and supply arrangements. For those agreements with variable terms, we do not estimate the total obligation beyond any minimum quantities or pricing as of the reporting date. Licensing agreements under which we commit to minimum royalty payments, some of which are subject to adjustment, may be terminated prior to the expiration of underlying intellectual property under certain circumstances. Annual minimum payments for noncancelable purchase obligations as of December 31, 2023 totaled $290 million, less than half of which are due within the next twelve months.
v3.24.0.1
Stockholders' Equity
12 Months Ended
Dec. 31, 2023
Equity [Abstract]  
Stockholders' Equity
6. STOCKHOLDERS’ EQUITY
The 2015 Stock and Incentive Compensation Plan (the 2015 Stock Plan) and the New Hire Stock and Incentive Plan allow for the issuance of stock options, performance stock options, restricted stock units and awards, and performance stock units. In Q2 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance by 8.0 million shares. As of December 31, 2023, approximately 8.2 million shares remained available for future grants under the 2015 Stock Plan. There is no set number of shares reserved for issuance under the New Hire Stock and Incentive Plan.
Restricted Stock

We issue restricted stock units (RSU) and performance stock units (PSU), both of which are considered restricted stock. We grant restricted stock pursuant to the 2015 Stock Plan and satisfy such grants through the issuance of either new shares or shares from treasury stock. RSU are share awards that, upon vesting, will deliver to the holder shares of our common stock. RSU generally vest over a four-year period with equal vesting annually. We issue two different PSU awards. We issue PSU for which the number of shares issuable at the end of a three-year performance period is based on our performance relative to specified earnings per share targets and continued employment through the vesting period (EPS PSU). During 2023, we began to issue PSU with a market condition that vest based on the Company’s relative total shareholder return as compared to a peer group of companies measured over a three-fiscal year performance period and continued employment through the vesting period (rTSR PSU). Depending on the actual performance over the measurement period, an rTSR PSU award recipient could receive up to 175% of the granted award.

Restricted stock activity was as follows:
Restricted
Stock Units
(RSU) (1)
Performance
Stock Units
(PSU) (2)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 3, 20211,721 — $313.35 $— 
Awarded259 456 $438.46 $471.63 
Vested(606)(72)$303.08 $492.55 
Cancelled(244)(56)$321.93 $475.38 
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987) $268.08 $ 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
_____________
(1)In connection with the GRAIL acquisition, replacement awards of 59,000 RSU were awarded to GRAIL employees in 2021.
(2)The number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. As of December 31, 2023, there were approximately 129,000 rTSR PSU granted. Awarded units are presented net of performance adjustments.

Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202320222021
Pre-tax intrinsic value of outstanding restricted stock:
RSU$306 $326 $430 
PSU$ $15 $125 
Fair value of restricted stock vested:
RSU$122 $162 $247 
PSU$ $49 $35 
Liability- Classified RSU

In Q1 2023, we granted RSU that were to be settled in cash if stockholder approval to increase our share reserve under the amended and restated 2015 Stock Plan was not obtained. In Q2 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance. Upon such approval, all RSU previously accounted for as liability-classified awards, approximately 557,000 RSU, were reclassified to stockholders equity and accounted for prospectively as equity awards. There were no RSU liability-classified awards outstanding as of December 31, 2023.

Stock Options

Stock option activity was as follows:
Units in thousandsOptionsWeighted-Average
Exercise Price
Performance Stock Options(1)
Weighted-Average
Exercise Price
Outstanding at January 3, 202110 $59.11 — $— 
Granted— $— 48 $86.73 
Exercised(2)$20.06 (21)$86.72 
Cancelled— $— (10)$89.63 
Outstanding at January 2, 2022$66.42 17 $85.54 
Granted180 $330.25 — $— 
Exercised(1)$6.55 — $— 
Outstanding at January 1, 2023187 $319.72 17 $85.54 
Exercised(8)$71.09 (1)$16.69 
Cancelled(144)$330.25  $ 
Outstanding at December 31, 202335 $330.25 16 $87.74 
Exercisable at December 31, 20239 $330.25  $ 
_____________
(1)In connection with the GRAIL acquisition, we issued replacement performance stock options to GRAIL employees in 2021. The number of units reflect awards that have been granted and for which it is assumed to be probable that the underlying performance goals will be achieved.

The aggregate intrinsic value of options outstanding as of December 31, 2023 was zero. Aggregate intrinsic value represents the product of the number of options outstanding multiplied by the difference between our closing stock price per share on the last trading day of the fiscal period, which was $139.24 as of December 29, 2023, and the exercise price. Total intrinsic value of options exercised was $1 million, zero, and $1 million in 2023, 2022, and 2021, respectively. The weighted-average remaining life of options outstanding was 5.2 years as of December 31, 2023.

The aggregate intrinsic value of performance stock options outstanding as of December 31, 2023 was $1 million. The total intrinsic value of performance stock options exercised was zero and $6 million in 2023 and 2021, respectively. No performance stock options were exercised in 2022. Outstanding performance stock options, in general, have contractual terms of ten years from the respective grant dates.

Other Liability-Classified Awards

We grant cash-based equity incentive awards to GRAIL employees. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, is used. The awards generally have terms of four years and vest in four equal installments on each anniversary of the grant date, subject to continued employment through the vesting period. These awards are accounted for as liability-classified awards.
Cash-based equity incentive award activity was as follows:

In millions
Outstanding at January 3, 2021$— 
Granted218 
Cancelled(42)
Change in fair value
Outstanding at January 2, 2022184 
Granted168 
Vested and paid in cash(41)
Cancelled(41)
Change in fair value23 
Outstanding at January 1, 2023293 
Granted116 
Vested and paid in cash(77)
Cancelled(32)
Change in fair value(8)
Outstanding at December 31, 2023$292 
Estimated liability as of December 31, 2023 (included in accrued liabilities)$55 

We recognized share-based compensation expense of $95 million, $67 million and $11 million in 2023, 2022 and 2021, respectively. As of December 31, 2023, approximately $237 million of total unrecognized compensation cost related to awards issued to date was expected to be recognized over a weighted-average period of approximately 2.5 years.

In connection with the acquisition of GRAIL, we assumed a performance-based award for which vesting is based on GRAIL’s future revenues. The award has an aggregate potential value of up to $78 million and expires, to the extent unvested, in August 2030. As of December 31, 2023, it was not probable that the performance conditions associated with the award will be achieved and, therefore, no share-based compensation expense, or corresponding liability, has been recognized in the consolidated financial statements to-date. We assess the probability of achieving the performance conditions associated with the award on a quarterly basis at each reporting period.

Employee Stock Purchase Plan

A total of 15.5 million shares of our common stock have been reserved for issuance under our 2000 Employee Stock Purchase Plan, or ESPP. The ESPP permits eligible employees to purchase common stock at a discount through payroll deductions during defined offering periods. The price at which stock is purchased under the ESPP is equal to 85% of the fair market value of the common stock on the first day of the offering period or purchase date, whichever is lower. The initial offering period commenced in July 2000.

Approximately 0.4 million, 0.3 million and 0.2 million shares during 2023, 2022 and 2021, respectively, were issued under the ESPP. As of December 31, 2023 and January 1, 2023, there were approximately 12.4 million and 12.8 million shares available for issuance under the ESPP, respectively.
The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the ESPP were as follows:
202320222021
Risk-free interest rate
0.78% - 5.54%
 0.06% - 2.98%
0.06% - 0.12%
Expected volatility
41% - 51%
 37% - 51%
37% - 47%
Expected term
0.5 - 1.1 years
 0.5 - 1.0 year
0.5 - 1.0 year
Expected dividends
0%
0%0%
Weighted-average grant-date fair value per share$49.87 $50.22 $134.47 

Share Repurchases

We did not repurchase any shares during 2023, 2022, or 2021. As of December 31, 2023, authorizations to repurchase approximately $15 million of our common stock remained available under the $750 million share repurchase program authorized by our Board of Directors on February 5, 2020. The repurchases may be completed under a 10b5-1 plan or at management’s discretion.

Share-Based Compensation
    
Share-based compensation expense, which includes expense for both equity and liability-classified awards, reported in our consolidated statements of operations was as follows:

In millions202320222021
Cost of product revenue$29 $26 $23 
Cost of service and other revenue7 
Research and development155 153 276 
Selling, general and administrative189 181 638 
Share-based compensation expense, before taxes380 366 941 
Related income tax benefits(87)(83)(64)
Share-based compensation expense, net of taxes$293 $283 $877 

In connection with the acquisition of GRAIL, we recognized share-based compensation expense of $615 million in 2021 related to the fair value of accelerated equity awards attributable to the post-combination period, of which $167 million was recorded in research and development expense and $448 million in selling, general and administrative expense. We also recognized $2 million, $10 million and $24 million of expense in 2023, 2022 and 2021, respectively, related to the replacement awards.

In February 2021, we modified the metrics and reduced the maximum potential payouts for our performance stock units granted in 2019 and 2020, which vested at the end of the three-year periods ended January 2, 2022 and January 1, 2023, respectively. The modifications affected 52 employees with units granted in 2019, which resulted in total incremental share-based compensation cost of approximately $41 million, and 72 employees with units granted in 2020, which resulted in total incremental share-based compensation cost of approximately $65 million.

As of December 31, 2023, approximately $496 million of total unrecognized compensation cost related to restricted stock, including RSU and PSU, stock options, including performance stock options, and ESPP shares issued to date was expected to be recognized over a weighted-average period of approximately 2.3 years.
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details
12 Months Ended
Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Supplemental Balance Sheet and Statement of Operations Details
7. SUPPLEMENTAL BALANCE SHEET AND STATEMENT OF OPERATIONS DETAILS
Accounts Receivable
In millionsDecember 31,
2023
January 1,
2023
Trade accounts receivable, gross$741 $675 
Allowance for credit losses(7)(4)
Total accounts receivable, net$734 $671 

Inventory
In millionsDecember 31,
2023
January 1,
2023
Raw materials$276 $247 
Work in process402 386 
Finished goods30 28 
Inventory, gross708 661 
Inventory reserve(121)(93)
Total inventory, net$587 $568 

Property and Equipment
In millionsDecember 31,
2023
January 1,
2023
Leasehold improvements$803 $759 
Machinery and equipment684 644 
Computer hardware and software463 424 
Furniture and fixtures55 50 
Buildings44 44 
Construction in progress96 132 
Total property and equipment, gross2,145 2,053 
Accumulated depreciation(1,138)(962)
Total property and equipment, net$1,007 $1,091 

Property and equipment, net included non-cash expenditures of $12 million, $16 million and $17 million in 2023, 2022, and 2021, respectively, which were excluded from the consolidated statements of cash flows.

Accrued Liabilities
In millionsDecember 31,
2023
January 1,
2023
Legal contingencies(1)
$484 $473 
Contract liabilities, current portion252 245 
Accrued compensation expenses(2)
223 188 
Accrued taxes payable79 97 
Operating lease liabilities, current portion86 76 
Liability-classified equity incentive awards55 36 
Other, including warranties(3)
146 117 
Total accrued liabilities$1,325 $1,232 
_____________
(1)See note “8. Legal Proceedings” for additional details.
(2)Included employee separation costs related to restructuring activities.
(3)See table below for changes in the reserve for product warranties.
Changes in the reserve for product warranties were as follows:
In millions
Balance as of January 3, 2021$13 
Additions charged to cost of product revenue33 
Repairs and replacements(24)
Balance as of January 2, 202222 
Additions charged to cost of product revenue23 
Repairs and replacements(27)
Balance as of January 1, 202318 
Additions charged to cost of product revenue42 
Repairs and replacements(39)
Balance as of December 31, 2023$21 
Restructuring
In Q2 2023, we implemented a cost reduction initiative that included workforce reductions, the consolidation of certain facilities and other actions to reduce expenses, all as part of a plan to realign operating expenses while maintaining focus on our innovation roadmap and sustainable long-term growth. In 2023, we recorded pre-tax restructuring charges primarily consisting of asset impairment charges related to our facilities and employee separation costs.
A summary of the pre-tax restructuring charges recorded in 2023 are as follows:

In millions
Employee separation costs$48 
Asset impairment charges (1)
100 
Other costs
Total restructuring charges (2)
$152 
_____________
(1)Primarily related to impairment of right-of-use assets and leasehold improvements for our i3 and Foster City campuses in California.
(2)For 2023, $122 million was recorded in SG&A expense, $24 million in R&D expense, with the remainder recorded in cost of revenue. These restructuring activities primarily relate to our Core Illumina segment.

During 2023, we fully exited our i3 campus in San Diego, California, which resulted in a right-of-use asset impairment of $38 million, and we exited a portion of our campus in Foster City, California, which resulted in a right-of-use asset impairment of $21 million. These impairments were recognized in selling, general and administrative expense. The impairments were determined by comparing the fair value of the impacted right-of-use asset to the carrying value of the asset as of the impairment measurement date. The fair value of the right-of-use asset was estimated using the discounted future cash flows method, which includes estimates and assumptions for future sublease rental rates that reflect current sublease market conditions, as well as a discount rate. The estimates and assumptions used in our assessment represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. We also recorded $16 million and $22 million of leasehold improvement impairments related to the exits of our i3 and Foster City campuses, respectively, in 2023, recognized in selling, general and administrative expense. We continue to evaluate our options with respect to the rest of our campus in Foster City, California. As of December 31, 2023, we had remaining assets, consisting primarily of right-of-use assets and leasehold improvements, related to our Foster City campus of approximately $136 million.
A summary of the restructuring liability is as follows:

In millions
Employee Separation Costs (1)
Other CostsTotal
Expense recorded in 2023$48 $$52 
Cash paid during 2023(31)(3)(34)
Amount recorded in accrued liabilities as of YTD 2023
$17 $$18 
Estimated total restructuring costs to still be incurred
$$— $
_____________
(1)It is expected that substantially all of the employee separation related restructuring charges will be incurred and paid by the end of Q1 2024.

Other (Expense) Income, Net

In millions202320222021
Gain on previously held investment in GRAIL$ $— $899 
Gain on exchange of GRAIL contingent value rights — 86 
Gain (loss) on Helix contingent value right10 (7)30 
Gain on derivative assets related to terminated acquisition — 26 
(Losses) gains on strategic investments, net(40)(122)18 
Other1 (13)
Other (expense) income, net$(29)$(142)$1,068 
v3.24.0.1
Legal Proceedings
12 Months Ended
Dec. 31, 2023
Commitments and Contingencies Disclosure [Abstract]  
Legal Proceedings
8. LEGAL PROCEEDINGS
We are involved in various lawsuits and claims arising in the ordinary course of business, including actions with respect to intellectual property, employment, and contractual matters. In connection with these matters, we assess, on a regular basis, the probability and range of possible loss based on the developments in these matters. A liability is recorded in the consolidated financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. Because litigation is inherently unpredictable and unfavorable resolutions could occur, assessing contingencies is highly subjective and requires judgments about future events. We regularly review outstanding legal matters to determine the adequacy of the liabilities accrued and related disclosures in consideration of many factors, which include, but are not limited to, past history, scientific and other evidence, and the specifics and status of each matter. We may change our estimates if our assessment of the various factors changes and the amount of ultimate loss may differ from our estimates, resulting in a material effect on our business, financial condition, results of operations, and/or cash flows.
Acquisition of GRAIL

Our acquisition of GRAIL remains subject to ongoing legal and regulatory proceedings in the United States and in the European Union.

On March 30, 2021, the U.S. Federal Trade Commission (the FTC) filed an administrative complaint and a motion for a preliminary injunction in the United States District Court for the District of Columbia. In both actions, the FTC alleged that our acquisition of GRAIL would violate Section 7 of the Clayton Act, as amended, 15 U.S.C. § 18. We filed an answer to the FTC’s complaint in federal district court on April 6, 2021, and in the administrative court on April 13, 2021. On April 20, 2021, the United States District Court for the District of Columbia granted our motion to transfer venue to the United States District Court for the Southern District of California. On May 28, 2021, the district court granted the FTC’s motion to dismiss the complaint without prejudice. The administrative trial commenced on August 24, 2021. On September 1, 2022, the administrative law judge (the ALJ) ruled in favor of Illumina and found that the acquisition of GRAIL did not violate Section 7 of the Clayton Act. In the decision, the ALJ found that the FTC’s
complaint counsel had failed to prove its prima facie case that Illumina’s acquisition of GRAIL would result in harm to competition in a putative market for multi-cancer early detection (MCED) tests. The FTC’s complaint counsel appealed the ALJ’s decision to the full FTC on September 2, 2022. The appeal was fully briefed as of November 10, 2022, and oral argument occurred on December 13, 2022. On March 31, 2023, the FTC issued an opinion and order (the FTC Order) requiring Illumina to divest GRAIL, reversing the ALJ’s ruling. On April 5, 2023, Illumina filed a petition for review of the FTC Order in the U.S. Court of Appeals for the Fifth Circuit. On April 24, 2023, the FTC granted a motion staying in its entirety the FTC Order pending resolution of Illumina’s Fifth Circuit appeal. The appeal was fully briefed as of August 16, 2023, and oral argument occurred on September 12, 2023. On December 15, 2023, the Fifth Circuit issued its opinion and order, in which the court ruled that the Commission applied the incorrect standard in assessing Illumina’s open offer contract, and on that basis vacated the FTC Order and remanded the case to the Commission for reconsideration of the effects of the open offer contract under the proper standard as described in the Fifth Circuit’s decision, and in all other respects upheld the Commission’s decision.

On April 19, 2021, the European Commission accepted a request for a referral of the GRAIL acquisition for European Union merger review, submitted by a Member State of the European Union (France), and joined by several other Member States (Belgium, Greece, Iceland, the Netherlands and Norway), under Article 22(1) of Council Regulation (EC) No 139/2004 (the EU Merger Regulation). The European Commission had never solicited referrals to take jurisdiction over an acquisition of a U.S. company that had no revenue in Europe. On April 28, 2021, we filed an action in the General Court of the European Union (the EU General Court) asking for annulment of the European Commission’s assertion of jurisdiction to review the acquisition under Article 22 of the EU Merger Regulation, as the acquisition does not meet the jurisdictional criteria under the EU Merger Regulation or under the national merger control laws of any Member State of the European Union. On December 16, 2021, the EU General Court held a hearing regarding the European Commission’s assertion of jurisdiction. On July 13, 2022, the EU General Court reached a decision in favor of the European Commission, holding that the European Commission has jurisdiction under the EU Merger Regulation to review the acquisition. On September 22, 2022, we filed an appeal in the Court of Justice of the European Union asking for annulment of the EU General Court’s decision. On December 12, 2023, the Court of Justice of the European Union held a hearing on the appeal.

On October 29, 2021, the European Commission adopted an order imposing interim measures (the Initial Interim Measures Order). As the Initial Interim Measures Order was set to expire on November 3, 2022, the European Commission adopted a new order imposing interim measures (the New Interim Measures Order) on October 28, 2022. On December 1, 2021, we filed an action with the EU General Court asking for annulment of the Initial Interim Measures Order. The hearing of that application has been stayed pending our appeal of the judgment of the EU General Court regarding the European Commission’s assertion of jurisdiction. On January 10, 2023, we filed an action with the EU General Court asking for annulment of the New Interim Measures Order. On January 20, 2023, the European Commission requested that these proceedings be stayed pending our appeal on jurisdiction. We submitted a filing indicating that we had no objections to the European Commission’s request, and the EU General Court stayed the proceedings on February 21, 2023.

On September 6, 2022, the European Commission announced that it had completed its Phase II review of the acquisition of GRAIL and adopted a final decision (the Prohibition Decision), which found that, in its view, our acquisition of GRAIL was incompatible with the internal market in Europe because it results in a significant impediment to effective competition. On November 17, 2022, we filed an action with the EU General Court asking for annulment of the Prohibition Decision.

On October 12, 2023, the European Commission adopted a decision requiring us to (among other things) divest GRAIL, and replacing the interim measures set forth in the New Interim Measures Order with substantially equivalent transitional measures (the EC Divestment Decision). On December 22, 2023, we filed an action with the EU General Court seeking an annulment of the EC Divestment Decision.
On July 12, 2023, the European Commission adopted a final decision finding that we breached the EU Merger Regulation by, in its view, acquiring the possibility to exert decisive influence over GRAIL and exerting such influence during the pendency of the European Commission’s review (the Article 14(2)(b) Decision). The European Commission therefore imposed a fine pursuant to Article 14(2)(b) of the EU Merger Regulation of approximately €432 million, representing the maximum fine of 10% of our consolidated annual revenues for fiscal year 2022. We provided guarantees in October 2023 to satisfy the obligation in lieu of cash payment while we appeal the European Commission’s jurisdictional decision and fine decision. The fine is accruing interest at a rate of 5.5% per annum, beginning in October 2023, while it is outstanding. As of December 31, 2023, we accrued $484 million, including related foreign currency losses and accrued interest, included in accrued liabilities. We appealed the Article 14(2)(b) Decision on September 26, 2023.

On December 17, 2023, we announced that we will divest GRAIL.
SEC Inquiry Letter

In July 2023, we were informed that the staff of the SEC was conducting an investigation relating to Illumina and was requesting documents and communications primarily related to Illumina’s acquisition of GRAIL and certain statements and disclosures concerning GRAIL, its products and its acquisition, and related to the conduct and compensation of certain members of Illumina and GRAIL management, among other things. Illumina is cooperating with the SEC in this investigation.
Derivative and Class Action Complaint

On October 17, 2023, a stockholder derivative and class action complaint captioned Icahn Partners LP, et al. v. deSouza, et al., purportedly brought on behalf of Illumina and public holders of Illumina’s common stock, was filed in the Delaware Court of Chancery against certain current and former directors (including our former Chief Executive Officer). We are named as a nominal defendant in the complaint. The lawsuit alleges the named directors breached their fiduciary duties by knowingly causing Illumina to unlawfully close the GRAIL acquisition, concealing material facts related to the GRAIL acquisition and making inadequate disclosures. Prior to the filing of the complaint, the purported stockholders did not make a demand that our Board of Directors pursue the claims asserted therein. The complaint seeks damages, costs and expenses, including attorney fees, the certification and consolidation of a putative class, the issuance of amended disclosures, the removal of conflicted directors and declaratory and other equitable relief. Since the lawsuit is brought in part on behalf of Illumina as a nominal defendant, the alleged damages were allegedly suffered by us.

On November 1, 2023, the defendants filed a motion to dismiss the complaint, which has not yet been briefed. On the same day, Illumina—joined by the director defendants—moved to strike portions of the complaint that contain improperly included confidential and privileged information. On January 16, 2024, the Court granted the motion to strike. On January 23, 2024, plaintiffs filed a motion seeking re-argument of the Court’s order granting the motion to strike. On December 6, 2023, the plaintiffs moved to expedite the proceedings with respect to their direct claims. The director defendants opposed that motion and Illumina joined their opposition. On January 19, 2023, the court denied plaintiffs’ motion to expedite. In light of the fact that the lawsuit is in an early stage, we cannot predict the ultimate outcome of the suit. We deny the allegations in the complaint and intend to vigorously defend the litigation.
Securities Class Actions

Federal Securities Class Actions. On November 11, 2023, the first of three securities class action complaints was filed against Illumina and certain of its current and former executive officers in the United States District Court for the Southern District of California. The first-filed case is captioned Kangas v. Illumina, Inc. et al., the second-filed case is captioned Roy v. Illumina, Inc. et al., and the third-filed case is captioned Louisiana Sheriffs’ Pension & Relief Fund v. Illumina, Inc. et al. (collectively, the “Actions”). The complaints generally allege, among other things, that defendants made materially false and misleading statements and omitted material facts relating to Illumina’s acquisition of Grail. The complaints seek unspecified damages, interest, fees, and costs. On January 9, 2024, four movants filed motions to consolidate the Actions and to appoint a lead plaintiff (“Lead Plaintiff Motions”). We expect the court to consolidate the three actions and appoint a lead plaintiff in the coming months.
State Securities Class Actions. On February 2, 2024, the first of two additional securities class actions was filed against Illumina, certain of its officers and directors, and several other individuals and entities in the Superior Court of the State of California, County of San Mateo, captioned Loren Scott Mar v. Illumina, et al. and Scott Zerzanek v. Illumina, Inc. et al.. Both complaints generally allege, among other things, that defendants made materially false and misleading statements and omitted material facts in the November 2020 and February 2021 registration statements and prospectus relating to Illumina’s acquisition of Grail. The complaints seek unspecified damages, interest, fees, and costs.

We deny the allegations in the complaints and intend to vigorously defend the litigation. In light of the fact that the lawsuits are in an early stage, we cannot predict the ultimate outcome of the suits.
DOJ Civil Investigative Demand

On January 18, 2024, we received a civil investigative demand (CID) from the U.S. Department of Justice, requiring production of certain documents and information in the course of a False Claims Act investigation to determine whether there is or has been a violation of 31 U.S.C. § 3729. The False Claims Act investigation concerns allegations that the Company caused the submission of false claims to Medicare and other federal government programs because it misrepresented its compliance with cybersecurity requirements to the Food and Drug Administration and other federal agencies that purchase its devices. The Company is preparing its response and cooperating with the government.
BGI Genomics Co. Ltd. and its Affiliates
As previously disclosed, we were engaged in litigation in various U.S. jurisdictions with BGI Genomics Co. Ltd (BGI) and certain of its affiliates, including Complete Genomics, Inc. (CGI) since June of 2019. On July 14, 2022, we entered into a Settlement and License Agreement with BGI and CGI (the “Agreement”). Pursuant to the terms of the Agreement, we agreed to pay CGI a one time payment of $325 million. We allocated the $325 million payment on a relative fair value basis, resulting in $180 million capitalized as an intangible asset in 2022 for the value of the license, which is amortized over a period of 6.5 years on a straight-line basis, $150 million allocated to the release of past damages claimed, and a $5 million gain for damages awarded to us. The fair value of the license was estimated using a discounted cash flow model, which included assumptions for projected revenues covered by the license, an estimated royalty rate and a discount rate. The fair value of the past damages claimed was estimated based on applicable historical revenues and an estimated royalty rate. These inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value.
v3.24.0.1
Income Taxes
12 Months Ended
Dec. 31, 2023
Income Tax Disclosure [Abstract]  
Income Taxes
9. INCOME TAXES
(Loss) income before income taxes summarized by region was as follows:
In millions202320222021
United States$(1,735)$(4,942)$(115)
Foreign618 606 999 
Total (loss) income before income taxes$(1,117)$(4,336)$884 
The provision for income taxes consisted of the following:
In millions202320222021
Current:   
Federal$(5)$(11)$54 
State6 27 37 
Foreign77 75 107 
Total current provision78 91 198 
Deferred:
Federal(13)40 (50)
State(26)(47)(23)
Foreign5 (16)(3)
Total deferred benefit(34)(23)(76)
Total tax provision$44 $68 $122 

The provision for income taxes reconciles to the amount computed by applying the federal statutory rate to (loss) income before taxes as follows:
In millions202320222021
Tax at federal statutory rate$(235)$(911)$186 
State, net of federal benefit(16)(9)13 
Research and other credits(42)(46)(23)
Change in valuation allowance48 62 33 
Impact of R&D expense capitalization86 87 — 
Impact of net operating losses on GILTI and U.S. foreign tax credits61 60 — 
Impact of foreign operations(50)(81)(80)
Impact of foreign derived intangible income (FDII) deduction1 (1)(12)
Stock compensation31 20 (10)
Officer compensation(4)13 
Accrual of European Commission fine3 96 — 
Goodwill impairment149 822 — 
Impact of acquisition related items8 (27)(16)
Other4 (8)18 
Total tax provision$44 $68 $122 

We have elected to account for the global intangible low-taxed income (GILTI) as a period cost in our consolidated financial statements.

The impact of foreign operations primarily represents the difference between the actual provision for income taxes for our legal entities that operate primarily in jurisdictions that have statutory tax rates lower than the U.S. federal statutory tax rate of 21%. The most significant tax benefits from foreign operations were from our earnings in Singapore, which had a statutory tax rate of 17% in 2023. The impact of foreign operations also includes the impact of GILTI and the U.S. foreign tax credit impact of non-U.S. earnings before the tax impact of net operating losses, and uncertain tax positions related to foreign items.

The impact of R&D expense capitalization is primarily the income tax expense impact of capitalizing research and development expenses for tax purposes on GILTI and the utilization of the U.S. foreign tax credits.
The impact of net operating losses on GILTI and U.S. foreign tax credits is primarily the income tax expense impact of GRAIL pre-acquisition net operating losses on GILTI and the utilization of the U.S. foreign tax credits.

The impact of acquisition related items includes the income tax expense impact of the gain on our previously held investment in GRAIL, acquisition related compensation, continuation payments, transaction costs, and changes to the contingent value rights associated with the GRAIL acquisition.

Significant components of deferred tax assets and liabilities were as follows:
In millionsDecember 31,
2023
January 1,
2023
Deferred tax assets:  
Net operating losses$392 $408 
Tax credits211 157 
Other accruals and reserves49 40 
Stock compensation15 20 
Capitalized U.S. R&D expenses158 97 
Other amortization115 247 
Operating lease liabilities146 156 
Property and equipment4 — 
Investments7 
Other56 38 
Total gross deferred tax assets1,153 1,168 
Valuation allowance on deferred tax assets(251)(203)
Total deferred tax assets
902 965 
Deferred tax liabilities:  
Purchased intangible amortization(734)(800)
Property and equipment (11)
Operating lease right-of-use assets(88)(112)
Other(25)(18)
Total deferred tax liabilities(847)(941)
Deferred tax assets, net$55 $24 

A valuation allowance is established when it is more likely than not the future realization of all or some of the deferred tax assets will not be achieved. The evaluation of the need for a valuation allowance is performed on a jurisdiction-by-jurisdiction basis and includes a review of all available positive and negative evidence, including operating results and forecasted ranges of future taxable income. Based on the available evidence as of December 31, 2023, we were not able to conclude it is more likely than not certain deferred tax assets will be realized. Therefore, a valuation allowance of $251 million was recorded against certain U.S. and foreign deferred tax assets.     

As of December 31, 2023, we had net operating loss carryforwards for federal and state tax purposes of $860 million and $1,874 million, respectively, which will begin to expire in 2024 and 2025, respectively, unless utilized prior. We also had federal and state tax credit carryforwards of $105 million and $223 million, which will begin to expire in 2031 and 2027, respectively, unless utilized prior.

Pursuant to Section 382 and 383 of the Internal Revenue Code, utilization of net operating losses and credits may be subject to annual limitations in the event of any significant future changes in its ownership structure. These annual limitations may result in the expiration of net operating losses and credits prior to utilization. The deferred tax assets as of December 31, 2023 are net of any previous limitations due to Section 382 and 383.
Our manufacturing operations in Singapore operate under various tax holidays and incentives, the first of which began to expire in 2023. These tax holidays and incentives resulted in a $75 million, $56 million, and $82 million decrease to the provision for income taxes in 2023, 2022, and 2021, respectively. These tax holidays and incentives resulted in an increase in diluted (loss) earnings per share of $0.47, $0.35, and $0.55, in 2023, 2022, and 2021, respectively.

As of December 31, 2023, we asserted that $1,855 million of foreign earnings would not be indefinitely reinvested, and accordingly, recorded a deferred tax liability of $25 million.

The following table summarizes the gross amount of our uncertain tax positions:
In millionsDecember 31,
2023
January 1,
2023
January 2,
2022
Balance at beginning of year$153 $131 $80 
Increases related to prior year tax positions27 12 19 
Decreases related to prior year tax positions(2)(3)(1)
Increases related to current year tax positions42 42 39 
Decreases related to lapse of statute of limitations(10)(29)(6)
Balance at end of year$210 $153 $131 

Included in the balance of uncertain tax positions as of December 31, 2023 and January 1, 2023, was $156 million and $124 million, respectively, of net unrecognized tax benefits that, if recognized, would reduce the effective income tax rate in future periods.

Any interest and penalties related to uncertain tax positions are reflected in the provision for income taxes. We recognized expense of $2 million in 2023, income of $3 million in 2022, and expense of $1 million in 2021, related to potential interest and penalties on uncertain tax positions. We recorded a liability for potential interest and penalties of $6 million and $3 million as of December 31, 2023 and January 1, 2023, respectively.

Tax years 1997 to 2022 remain subject to future examination by the major tax jurisdictions in which we are subject to tax. The Internal Revenue Service completed an examination of the U.S. Corporation Income Tax Returns for tax years 2017, 2018, and 2020. Given the uncertainty of potential adjustments from examination as well as the potential expiration of the statute of limitations, it is reasonably possible that the balance of unrecognized tax benefits could change significantly over the next 12 months. Due to the number of years remaining that are subject to examination, we are unable to estimate the full range of possible adjustments to the balance of gross unrecognized tax benefits.
v3.24.0.1
Employee Benefit Plans
12 Months Ended
Dec. 31, 2023
Postemployment Benefits [Abstract]  
Employee Benefit Plans
10. EMPLOYEE BENEFIT PLANS
Retirement Plan

We have a 401(k) savings plan covering substantially all of our employees in the United States. Our contributions to the plan are discretionary. During 2023, 2022, and 2021, we made matching contributions of $36 million, $30 million, and $26 million, respectively.

Deferred Compensation Plan

The Illumina, Inc. Deferred Compensation Plan (the Plan) allows senior level employees to contribute up to 60% of their base salary and 100% of their variable cash compensation, and members of the board of directors to contribute up to 100% of their director fees and equity awards. Under the Plan, we credit the participants’ contributions with earnings that reflect the performance of certain independent investment funds. On a discretionary basis, we may also make employer contributions to participant accounts in any amount determined by us. The vesting schedules of employer contributions are at the sole discretion of the Compensation Committee. However, all employer contributions shall become 100% vested upon the occurrence of the participant’s disability, death or retirement or a change in control of Illumina. The benefits under this plan are unsecured. Participants are generally eligible to receive payment of their vested benefit at the end of their elected deferral period or after termination of their employment for any reason or at a later date to comply with the restrictions of Section 409A.
We also established a rabbi trust for the benefit of the participants under the Plan and have included the assets of the rabbi trust in the consolidated balance sheets. As of December 31, 2023 and January 1, 2023, the assets of the trust were $61 million and $52 million, respectively, and our liabilities were $59 million and $51 million, respectively. The assets and liabilities are classified as other assets and accrued liabilities, respectively, on the consolidated balance sheets. Changes in the values of the assets held by the rabbi trust are recorded in other (expense) income, net in the consolidated statements of operations, and changes in the values of the deferred compensation liabilities are recorded in operating expenses.
v3.24.0.1
Segments and Geographic Data
12 Months Ended
Dec. 31, 2023
Segment Reporting [Abstract]  
Segments and Geographic Data
11. SEGMENTS AND GEOGRAPHIC DATA
Reportable Segment Information

We have two reportable segments, Core Illumina and GRAIL. We do not allocate expenses between segments. Additionally, our CODM does not evaluate our operating segments using discrete asset information.

On August 18, 2021, we acquired GRAIL and it operates as a separate reportable segment. We have included the results of operations of GRAIL in our consolidated statements of operations from the date of acquisition. Core Illumina sells products and provides services to GRAIL, and vice versa, in accordance with contractual agreements between the entities.

Core Illumina:

Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina includes all of our operations, excluding the results of GRAIL.

GRAIL:

GRAIL is a healthcare company focused on early detection of multiple cancers.
 In millions202320222021
Revenue:
Core Illumina$4,438 $4,553 $4,519 
GRAIL93 55 12 
Eliminations(27)(24)(5)
Consolidated revenue$4,504 $4,584 $4,526 
Depreciation and amortization:
Core Illumina$273 $240 $200 
GRAIL159 154 51 
Consolidated depreciation and amortization$432 $394 $251 
Income (loss) from operations:
Core Illumina$552 $481 $808 
GRAIL(1,621)(4,657)(931)
Eliminations (3)— 
Consolidated (loss) income from operations$(1,069)$(4,179)$(123)
Capital expenditures:
Core Illumina$183 $262 $201 
GRAIL13 24 
Eliminations(1)— (1)
Consolidated capital expenditures$195 $286 $208 

Total other (expense) income, net primarily relates to Core Illumina and we do not allocate income taxes to our segments.

Geographic Data

Net long-lived assets, consisting of property and equipment and operating lease right-of-use assets, by region, were as follows:
In millionsDecember 31,
2023
January 1,
2023
United States$1,040 $1,237 
Singapore298 290 
United Kingdom136 149 
Other countries77 68 
Total net long-lived assets$1,551 $1,744 
Refer to note “2. Revenue” for revenue by geographic area.
v3.24.0.1
Pay vs Performance Disclosure - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Pay vs Performance Disclosure      
Net (loss) income $ (1,161) $ (4,404) $ 762
v3.24.0.1
Insider Trading Arrangements
3 Months Ended 12 Months Ended
Dec. 31, 2023
shares
Dec. 31, 2023
shares
Trading Arrangements, by Individual    
Rule 10b5-1 Arrangement Adopted true  
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Caroline Dorsa [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 16, 2023, Caroline Dorsa, Director, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on November 18, 2024 and provides for the purchase of up to $200,000 in shares.
Name Caroline Dorsa  
Title Director  
Adoption Date November 16, 2023  
Arrangement Duration 368 days  
Aggregate Available 200,000 200,000
Jacob Thaysen [Member]    
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   On November 22, 2023, Jacob Thaysen, our Chief Executive Officer, entered in a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on November 22, 2024 and provides for the purchase of up to $1,000,000 in shares.
Name Jacob Thaysen  
Title Chief Executive Officer  
Adoption Date November 22, 2023  
Arrangement Duration 366 days  
Aggregate Available 1,000,000 1,000,000
v3.24.0.1
Organization and Significant Accounting Policies (Policies)
12 Months Ended
Dec. 31, 2023
Accounting Policies [Abstract]  
Basis of Presentation The consolidated financial statements have been prepared in conformity with U.S. generally accepted accounting principles (GAAP) and include our accounts, our wholly-owned subsidiaries, and majority-owned or controlled companies. All intercompany transactions and balances have been eliminated in consolidation. Certain prior period amounts have been reclassified to conform to the current period presentation.
Variable Interest Entities (VIEs) We evaluate our ownership, contractual and other interests in entities that are not wholly-owned to determine if these entities are VIEs, and, if so, whether we are the primary beneficiary of the VIE. In determining whether we are the primary beneficiary of a VIE and therefore required to consolidate the VIE, we apply a qualitative approach that determines whether we have both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. We continuously perform this assessment, as changes to existing relationships or future transactions may result in the consolidation or deconsolidation of a VIE. As of December 31, 2023, there were no VIEs for which we were the primary beneficiary and for which we were required to consolidate.
Use of Estimates The preparation of the consolidated financial statements requires that management make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses, and related disclosures of contingent assets and liabilities. Though macroeconomic factors such as inflation, exchange rate fluctuations and concerns about an economic downturn present additional uncertainty, we continue to use the best information available to inform our critical accounting estimates. Actual results could differ from those estimates.
Fiscal Year
Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. References to 2023, 2022, and 2021 refer to fiscal years ended December 31, 2023, January 1, 2023, and January 2, 2022, respectively. Fiscal years 2023, 2022, and 2021 were all 52 weeks.
Functional Currency The U.S. dollar is the functional currency of our international operations. We re-measure foreign subsidiaries’ monetary assets and liabilities to the U.S. dollar and record the net gains or losses resulting from re-measurement in other (expense) income, net in the consolidated statements of operations.
Concentrations of Risk
Customers

We operate in markets that are highly competitive and rapidly changing. Significant technological changes, shifting customer needs, the emergence of competitive products or services with new capabilities, and other factors could negatively impact our operating results. A portion of our customers consist of university and research institutions that management believes are, to some degree, directly or indirectly supported by the United States Government. A significant change in current research funding, particularly with respect to the U.S. National Institutes of Health, could have an adverse impact on future revenues and results of operations.

International sales entail a variety of risks, including currency exchange fluctuations, longer payment cycles, and greater difficulty in accounts receivable collection. We are also subject to general geopolitical risks, such as political, social and economic instability, and changes in diplomatic and trade relations. The risks of international sales are mitigated in part by the extent to which sales are geographically distributed. Shipments to customers outside the United States comprised 48%, 50%, and 52% of total revenue in 2023, 2022, and 2021, respectively. Customers outside the United States represented 55% and 54% of our gross trade accounts receivable balance as of December 31, 2023 and January 1, 2023, respectively.

We had no customers that provided more than 10% of total revenue in 2023, 2022, and 2021. We perform regular reviews of customer activity and associated credit risks and do not require collateral or enter into netting arrangements. Historically, we have not experienced significant credit losses from accounts receivable.

Financial Instruments

We are also subject to risks related to our financial instruments, including cash and cash equivalents, investments, and accounts receivable. Most of our cash and cash equivalents as of December 31, 2023 were deposited with U.S. financial institutions, either domestically or with their foreign branches. Our investment policy restricts the amount of credit exposure to any one issuer to 5% of the portfolio or 5% of the total issue size outstanding at the time of purchase and to any one industry sector, as defined by Clearwater Analytics (Industry Sector Report), to 30% of the portfolio at the time of purchase. There is no limit to the percentage of the portfolio that may be maintained in debt securities, U.S. government-sponsored entities, U.S. Treasury securities, and money market funds. Historically, we have not experienced significant credit losses from financial instruments.

Suppliers

We require customized products and components that currently are available from a limited number of sources. We source certain key products and components included in our products from single vendors. Historically, we have not experienced significant issues sourcing materials to build our products.
Segments
We report segment information based on the management approach. This approach designates the internal reporting used by the Chief Operating Decision Maker (CODM) for making decisions and assessing performance as the source of our reportable segments. The CODM allocates resources and assesses the performance of each operating segment using information about its revenue and income (loss) from operations. Management evaluates the performance of our reportable segments based upon income (loss) from operations. Our CODM does not evaluate our operating segments using discrete asset information. We do not allocate expenses between segments.
Accounting Pronouncements Adopted and Accounting Pronouncements Pending Adoption
Accounting Pronouncements Adopted in 2022

In August 2020, the FASB issued ASU 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity’s Own Equity (Subtopic 815-40). The new standard reduces the number of accounting models for convertible debt instruments, amends the accounting for certain contracts in an entity’s own equity, and modifies how certain convertible instruments and contracts that may be settled in cash or shares impact the calculation of diluted earnings per share. Specifically, the guidance removes certain accounting models that separate the embedded conversion features from the host contract for convertible instruments and requires the use of the if-converted method to calculate diluted earnings per share. We adopted the standard on its effective date in the first quarter of 2022 using a modified retrospective approach by recognizing a cumulative-effect adjustment to retained earnings on January 3, 2022. We did not restate prior periods. As a result of the adoption, we increased our convertible senior notes and retained earnings, on January 3, 2022, by $43 million and $61 million, respectively, and decreased our deferred tax liabilities, included in other long-term liabilities on the consolidated balance sheets, and additional paid-in capital by $11 million and $93 million, respectively. Interest expense recognized post-adoption has decreased as a result of accounting for our convertible senior notes as a single liability measured at amortized cost. See note “5. Debt and Other Commitments” for additional details on the adoption of ASU 2020-06.

Accounting Pronouncements Pending Adoption

In December 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280) - Improvements to Reportable Segment Disclosures. The new standard requires a company to disclose incremental segment information on an annual and interim basis, including significant segment expenses and measures of profit or loss that are regularly provided to the chief operating decision maker (CODM). The standard is effective for us beginning in fiscal year 2024 and interim periods within fiscal year 2025, with early adoption permitted. We do not expect to early adopt the new standard. We are currently evaluating the impact of ASU 2023-07 on the consolidated financial statements and related disclosures and will adopt the new standard using a retrospective approach.

In December 2023, the FASB also issued ASU 2023-09, Income Taxes (Topic 740) - Improvements to Income Tax Disclosures. The new standard requires a company to expand its existing income tax disclosures, specifically related to the rate reconciliation and income taxes paid. The standard is effective for us beginning in fiscal year 2025, with early adoption permitted. We do not expect to early adopt the new standard. The new standard is expected to be applied prospectively, but retrospective application is permitted. We are currently evaluating the impact of ASU 2023-09 on the consolidated financial statements and related disclosures.
Revenue Recognition and Shipping and Handling Expenses
Our revenue is generated primarily from the sale of products and services. Product revenue primarily consists of sales of instruments and consumables used in genetic analysis. Service and other revenue primarily consists of revenue generated from genotyping and sequencing services, instrument service contracts, development and licensing agreements, and cancer detection testing services related to the GRAIL business.

We recognize revenue when control of our products and services is transferred to our customers in an amount that reflects the consideration we expect to receive from our customers in exchange for those products and services. This process involves identifying the contract with a customer, determining the performance obligations in the contract, determining the contract price, allocating the contract price to the distinct performance obligations in the contract, and recognizing revenue when the performance obligations have been satisfied. Revenue recognition for contracts with multiple deliverables is based on the separate satisfaction of each distinct performance obligation within the contract. A performance obligation is considered distinct from other obligations in a contract when it provides a benefit to the customer either on its own or together with other resources that are readily available to the customer and is separately identified in the contract. We consider a performance obligation satisfied once we have transferred control of a good or service to the customer, meaning the customer has the ability to use and obtain the benefit of the good or service. The contract price is allocated to each performance obligation in proportion to its standalone selling price. We determine our best estimate of standalone selling price using average selling prices over a rolling 12-month period coupled with an assessment of current market conditions. If the product or service has no history of sales or if the sales volume is not sufficient, we rely upon prices set by management, adjusted for applicable discounts.

Revenue from product sales is recognized generally upon delivery to the end customer, which is when control of the product is deemed to be transferred. Invoicing typically occurs upon shipment and payment is typically due within 30
days from invoice. In instances where right of payment or transfer of title is contingent upon the customer’s acceptance of the product, revenue is deferred until all acceptance criteria have been met. Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer. Revenue from instrument service contracts is recognized as the services are rendered, typically evenly over the contract term. Revenue from development and licensing agreements generally includes upfront and periodic licensing fees, contract research and development services, or payments for development and regulatory milestones. Revenue for these agreements is recognized when each distinct performance obligation is satisfied.

Revenue is recorded net of discounts, distributor commissions, and sales taxes collected on behalf of governmental authorities. Employee sales commissions are recorded as selling, general and administrative expense when incurred as the amortization period for such costs, if capitalized, would have been one year or less.
In certain markets, products and services are sold to customers through distributors. In most sales through distributors, the product is delivered directly to customers by us. The terms of sales transactions through distributors are consistent with the terms of direct sales to customers.Shipping and handling expenses are included in cost of product revenue.
(Loss) Earnings per Share
Basic (loss) earnings per share is computed based on the weighted average number of common shares outstanding during the period. Diluted (loss) earnings per share is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. In loss periods, basic and diluted loss per share are identical since the effect of potentially dilutive common shares is antidilutive and therefore excluded.

Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. On January 3, 2022, we adopted ASU 2020-06. As a result, beginning in Q1 2022, we utilize the if-converted method to calculate the impact of convertible senior notes on diluted (loss) earnings per share. Prior to the adoption of ASU 2020-06, we applied the treasury stock method when calculating the potential dilutive effect, if any, of convertible senior notes which we intended to settle or have settled in cash the principal outstanding. Under the treasury stock method, convertible senior notes would have a dilutive impact when the average market price of our common stock exceeded the applicable conversion price of the respective notes. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares.
Fair Value Measurements
The fair value of assets and liabilities are based on the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value maximize the use of observable inputs and minimize the use of unobservable inputs. We use a fair value hierarchy with three levels of inputs, of which the first two are considered observable and the last unobservable, to measure fair value:

Level 1 — Quoted prices in active markets for identical assets or liabilities.
Level 2 — Inputs, other than Level 1, that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.
The carrying amounts of financial instruments such as cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable, and accrued liabilities approximate the related fair values due to the short-term maturities of these instruments.
Cash Equivalents
Cash equivalents are comprised of short-term, highly-liquid investments with maturities of 90 days or less at the date of purchase.
Equity Securities and Investments
We have strategic investments in privately-held companies (non-marketable equity securities) and companies that have completed initial public offerings (marketable equity securities). Our marketable equity securities are measured at fair value. Our non-marketable equity securities without readily determinable market values are initially measured at cost and adjusted to fair value for observable transactions for identical or similar investments of the same issuer or impairment. Equity investments are classified as current, short-term investments, or noncurrent, recorded in other assets, based on the nature of the securities and their availability for use in current operations. Unrealized gains and losses on our equity investments are recorded in other (expense) income, net in the consolidated statements of operations. Our equity investments are assessed for impairment quarterly. Impairment losses, equal to the difference between the carrying value and the fair value of the investment, are recorded in other (expense) income, net.

We use the equity method to account for investments through which we have the ability to exercise significant influence, but not control, over the investee. Such investments are recorded in other assets, and our share of net income or loss is recognized on a one quarter lag in other (expense) income, net.
Accounts Receivable
Trade accounts receivable are recorded at the net invoice value and are not interest-bearing. Receivables are considered past due based on the contractual payment terms. We reserve a percentage of our trade receivable balance based on collection history and current economic trends that we expect will impact the level of credit losses over the life of our receivables. These reserves are re-evaluated on a regular basis and adjusted, as needed. Once a receivable is deemed to be uncollectible, such balance is charged against the reserve.
Inventory Inventory is stated at the lower of cost or net realizable value, on a first-in, first-out basis. Inventory includes raw materials and finished goods that may be used in the research and development process, and such items are expensed as consumed or capitalized as property and equipment and depreciated. Inventory write-downs for slow-moving, excess, and obsolete inventories are estimated based on product life cycles, quality issues, historical experience, and usage forecasts.
Property and Equipment
Property and equipment are stated at cost, subject to review for impairment, and depreciated over the estimated useful lives of the assets, using the straight-line method. Depreciation of leasehold improvements is recorded over the shorter of the lease term or the estimated useful life of the related assets. Maintenance and repairs are expensed as incurred. When assets are sold, or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and any gain or loss is included in operating expense.

Costs incurred to develop internal-use software during the application development stage are recorded as computer software costs, at cost. Costs incurred in the development of such internal-use software, including external direct costs of materials and services and applicable compensation costs of employees devoted to specific software application development, are capitalized. Costs incurred outside of the application development stage are expensed as incurred.
Leases
We lease approximately 2.8 million square feet of office, lab, manufacturing, and distribution facilities under various non-cancellable operating lease agreements (real estate leases). Our real estate leases have remaining lease terms of approximately 1 year to 15 years, which represent the non-cancellable periods of the leases and include extension options that we determined are reasonably certain to be exercised. We exclude extension options that are not reasonably certain to be exercised from our lease terms, ranging from approximately 2 years to 20 years. Our lease payments consist primarily of fixed rental payments for the right to use the underlying leased assets over the lease terms, as well as payments for common-area-maintenance and administrative services. We often receive customary incentives from our landlords, such as reimbursements for tenant improvements and rent abatement periods, which effectively reduce the total lease payments owed for these leases. Leases are classified as operating or financing at commencement. We do not have any material financing leases.

Operating lease right-of-use assets and liabilities on our consolidated balance sheets represent the present value of our remaining lease payments over the remaining lease terms, less any impairments recorded for right-of-use assets. We do not allocate lease payments to non-lease components; therefore, fixed payments for common-area-maintenance and administrative services are included in our operating lease right-of-use assets and liabilities. We use our incremental borrowing rate to calculate the present value of our lease payments, as the implicit rates in our leases are not readily determinable. Operating lease costs consist primarily of the fixed lease payments included in our operating lease liabilities and are recorded on a straight-line basis over the lease terms. We sublease certain real estate to third parties and this sublease income is also recorded on a straight-line basis.
Business Combinations
Under the acquisition method of accounting, we allocate the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. These valuations require us to make estimates and assumptions, especially with respect to intangible assets. We record the excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, as goodwill. Costs that we incur to complete the business combination, such as legal and other professional fees, are expensed as they are incurred.
In connection with certain acquisitions, contingent consideration can be earned by the sellers upon completion of certain future performance milestones. In these cases, a liability is recorded on the acquisition date, as a component of accrued liabilities and/or other long-term liabilities, for an estimate of the acquisition-date fair value of the contingent consideration. These estimates require management judgment, including probabilities of achieving certain future milestones. Changes in the fair value of the contingent consideration subsequent to the acquisition date are recognized in selling, general and administrative expense in our consolidated statements of operations.

If the initial accounting for a business combination is incomplete by the end of a reporting period that falls within the measurement period (not to exceed a year from the date of acquisition), we report provisional amounts in our financial statements. During the measurement period, we adjust the provisional amounts recognized at the acquisition date to reflect new information obtained about facts and circumstances that existed as of the acquisition date that, if known, would have affected the measurement of the amounts recognized as of that date. We record these adjustments to the provisional amounts with a corresponding offset to goodwill. Any adjustments identified after the measurement period are recorded in the consolidated statements of operations.
Goodwill, Intangible Assets and Other Long-Lived Assets
Assets acquired, including intangible assets and capitalized in-process research and development (IPR&D), and liabilities assumed are measured at fair value as of the acquisition date. Goodwill, which has an indefinite useful life, represents the excess of cost over fair value of the net assets acquired. Intangible assets acquired in a business combination that are used for IPR&D activities are considered indefinite lived until the completion or abandonment of the associated research and development efforts. Upon reaching the end of the relevant research and development project (i.e., upon commercialization), the IPR&D asset is amortized over its estimated useful life. If the relevant research and development project is abandoned, the IPR&D asset is expensed in the period of abandonment.

Goodwill and IPR&D are not amortized; however, they are reviewed for impairment at least annually during the second quarter, or more frequently if an event occurs indicating the potential for impairment. Goodwill and IPR&D are considered to be impaired if the carrying value of the reporting unit or IPR&D asset exceeds its respective fair value.

We perform our goodwill impairment analysis at the reporting unit level, which aligns with our reporting structure and availability of discrete financial information. During the goodwill impairment review, we assess qualitative factors to determine whether it is more likely than not that the fair values of our reporting units are less than the carrying amounts, including goodwill. The qualitative factors include, but are not limited to, macroeconomic conditions, industry and market considerations, and our overall financial performance. If, after assessing the totality of these qualitative factors, we determine that it is not more likely than not that the fair values of our reporting units are less than the carrying amounts, then no additional assessment is deemed necessary. Otherwise, we proceed to compare the estimated fair values of the reporting units with the carrying values, including goodwill. If the carrying amount of a reporting unit exceeds its fair value, we record an impairment loss based on the difference. We may elect to bypass the qualitative assessment in a period and proceed to perform the quantitative goodwill impairment test.

The IPR&D impairment test is performed by comparing the fair value of the asset to its carrying amount. When testing indefinite-lived intangibles for impairment, we may assess qualitative factors to determine whether it is more likely than not that the asset is impaired. Alternatively, we may bypass this qualitative assessment and perform a quantitative impairment test. If the IPR&D asset is impaired, the carrying value of the IPR&D is written down to the revised fair value with the related impairment charge recognized in the period in which the impairment occurs.

Our identifiable intangible assets with a finite life are typically comprised of acquired developed technologies, licensed technologies, customer relationships, license agreements, and trade names. The cost of identifiable intangible assets with finite lives is generally amortized on a straight-line basis over the assets’ respective estimated useful lives.

We perform regular reviews to determine if any event has occurred that may indicate that intangible assets with finite useful lives and other long-lived assets are potentially impaired. If indicators of impairment exist, an impairment test is performed to assess the recoverability of the affected assets by determining whether the carrying amount of such assets exceeds the undiscounted expected future cash flows. If the affected assets are not recoverable, we estimate the fair value of the assets and record an impairment loss in an amount equal to the excess of the carrying value over the fair value. Factors that may indicate potential impairment include a significant decline in our stock price and market capitalization compared to the net book value, significant changes in the ability of a particular asset to generate positive cash flows for our strategic business objectives, and the pattern of utilization of a particular asset.
We review our operating lease right-of-use (ROU) assets for impairment whenever events or changes in circumstances indicate the carrying value of the ROU asset may not be recoverable. The evaluation is performed at the lowest level for which identifiable cash flows are largely independent of the cash flows of other groups of assets and liabilities. We consider a triggering event to reassess an ROU asset’s asset group to have occurred if we exit a portion of or the full facility or enter into a sublease. Factors that may indicate potential impairment include a significant decrease in the market price of an underlying leased asset group. If we conclude the carrying value of affected assets will not be recovered, we estimate the fair value of the assets and record an impairment in an amount equal to the excess of the carrying value over the fair value.
Derivative Financial Instruments
We are exposed to foreign exchange rate risks in the normal course of business and use derivative financial instruments to partially offset this exposure. We do not use derivative financial instruments for speculative or trading purposes. Foreign exchange contracts are carried at fair value in other current assets, other assets, accrued liabilities, or other long-term liabilities, as appropriate, on the consolidated balance sheets.

We use foreign exchange forward contracts to manage foreign currency risks related to monetary assets and liabilities denominated in currencies other than the U.S. dollar. These derivative financial instruments have terms of one month or less and are not designated as hedging instruments. Changes in fair value of these derivatives are recognized in other (expense) income, net, along with the re-measurement gain or loss on the foreign currency denominated assets or liabilities. As of December 31, 2023, we had foreign exchange forward contracts in place to hedge exposures to monetary assets and liabilities denominated in the euro, Japanese yen, Australian dollar, Canadian dollar, Singapore dollar, Chinese Yuan Renminbi, and British pound. As of December 31, 2023 and January 1, 2023, the total notional amounts of outstanding forward contracts in place for these foreign currency purchases were $926 million and $485 million, respectively. In July 2023, we entered into forward contracts for a total notional amount of €432 million to hedge the foreign currency exposure for the fine imposed by the European Commission on July 12, 2023.
We also use foreign currency forward contracts to hedge portions of our foreign currency exposure associated with forecasted revenue transactions. These derivative financial instruments have terms up to 24 months and are designated as cash flow hedges. Changes in fair value of our cash flow hedges are recorded as a component of accumulated other comprehensive income and are reclassified to revenue in the same period the underlying hedged transactions are recorded. We regularly review the effectiveness of our cash flow hedges and consider them to be ineffective if it becomes probable that the forecasted transactions will not occur in the identified period. Changes in fair value of the ineffective portions of our cash flow hedges, if any, are recognized in other (expense) income, net. As of December 31, 2023, we had foreign currency forward contracts in place to hedge exposures associated with forecasted revenue transactions denominated in the euro, Japanese yen, Australian dollar, Canadian dollar, and Chinese Yuan Renminbi. As of December 31, 2023 and January 1, 2023, the total notional amounts of outstanding cash flow hedge contracts in place for these foreign currency purchases were $628 million and $425 million, respectively.
Warranties We generally provide a one-year warranty on instruments. Additionally, we provide a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, an accrual is established for estimated warranty expenses based on historical experience as well as anticipated product performance. We periodically review the warranty reserve for adequacy and adjust the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.
Share-Based Compensation
Share-based compensation expense is incurred related to restricted stock, cash-based equity incentive awards, Employee Stock Purchase Plan (ESPP), and stock options. Forfeitures are accounted for, as incurred, as a reversal of share-based compensation expense related to awards that will not vest.
Restricted stock units (RSU) and performance stock units (PSU) are both considered restricted stock. The determination of the amount of share-based compensation expense for our PSU requires the use of certain estimates and assumptions that affect the amount of share-based compensation expense recognized in our consolidated statements of operations. The fair value of restricted stock and performance stock units that do not include a market condition is determined by the closing market price of our common stock on the date of grant. PSU that do not include a market condition represent a right to receive a certain number of shares of common stock based on the achievement of corporate performance goals and continued employment during the vesting period. At each reporting period, we reassess the probability of the achievement of such corporate performance goals and any increase or decrease in share-based compensation expense resulting from an adjustment in the estimated shares to be released is treated as a cumulative catch-up in the period of adjustment. The fair value of performance stock units that include a market condition is determined on the date of grant using a Monte Carlo simulation, which includes assumptions for expected volatility, risk-free interest rate and divided yield. These unobservable inputs represent a Level 3 measurement because they are supported by little or no market activity and reflect our own assumptions in measuring fair value. Share-based compensation expense is recognized based on the fair value on a straight-line basis over the requisite service periods of the awards. Compensation expense for PSU that include a market condition is recognized over the requisite service period regardless of whether the market conditions are achieved.

Cash-based equity incentive awards are classified as liability awards, as such awards will be settled in cash. For purposes of valuation and performance measurement of the awards, GRAIL’s stand-alone value calculation, as estimated by GRAIL based on its analysis and on input from independent valuation advisors and analyses, is used. The fair value of the awards is recorded over the respective vesting periods of the awards, with recognition of a corresponding liability recorded in accrued liabilities in the consolidated balance sheets. The awards are remeasured to fair value at each reporting date until the awards are settled, with changes in fair value recognized in share-based compensation expense.
The Black-Scholes-Merton option-pricing model is used to estimate the fair value of stock purchased under our ESPP and stock options granted. The model assumptions include expected volatility, term, dividends, and the risk-free interest rate. The expected volatility is generally determined by weighing the historical and implied volatility of our common stock. The historical volatility is generally commensurate with the estimated expected term. The implied volatility is calculated from the implied market volatility of exchange-traded call options on our common stock. The expected term is generally based on historical forfeiture experience, exercise activity, and on the terms and conditions of the stock awards. The expected dividend yield is determined to be 0% given that we have never declared or paid cash dividends on our common stock and do not anticipate paying such cash dividends. The risk-free interest rate is based upon U.S. Treasury securities with remaining terms similar to the expected term of the share-based awards.
Research and Development Research and development expenses include personnel expenses, contractor fees, facilities-related costs, material costs, and license fees. Expenditures relating to research and development are expensed in the period incurred.
Advertising Costs Advertising costs are expensed as incurred.
Restructuring
We measure and accrue liabilities associated with employee separation costs, which primarily consist of severance pay and other separation costs such as outplacement services and benefits, at fair value as of the date the plan is approved and when such costs are reasonably estimable. The fair value measurement of restructuring related liabilities requires certain assumptions and estimates to be made, such as the retention period of certain employees. It is our policy to use the best estimates based on facts and circumstances available at the time of measurement, review the assumptions and estimates periodically, and adjust the liabilities when necessary.
Income Taxes
The provision for income taxes is computed using the asset and liability method, under which deferred tax assets and liabilities are recognized for the expected future tax consequences of temporary differences between the financial reporting and tax bases of assets and liabilities, and for the expected future tax benefit to be derived from tax loss and credit carryforwards. Deferred tax assets and liabilities are determined using the enacted tax rates in effect for the years in which those tax assets are expected to be realized. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in the provision for income taxes in the period that includes the enactment date.

Deferred tax assets are regularly assessed to determine the likelihood they will be recovered from future taxable income. A valuation allowance is established when we believe it is more likely than not the future realization of all or some of a deferred tax asset will not be achieved. In evaluating the ability to recover deferred tax assets within the jurisdiction which they arise, we consider all available positive and negative evidence. Factors reviewed include the cumulative pre-tax book income for the past three years, scheduled reversals of deferred tax liabilities, history of earnings and reliable forecasting, projections of pre-tax book income over the foreseeable future, and the impact of any feasible and prudent tax planning strategies.
The impact of a tax position is recognized in the consolidated financial statements only if that position is more likely than not of being sustained upon examination by taxing authorities, based on the technical merits of the position. Any interest and penalties related to uncertain tax positions will be reflected in income tax expense.
v3.24.0.1
Organization and Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2023
Accounting Policies [Abstract]  
Schedule of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings Per Share, Earnings Per Share
The following table presents the calculation of weighted average shares used to calculate basic and diluted (loss) earnings per share:
 Years Ended
In millionsDecember 31,
2023
January 1,
2023
January 2,
2022
Weighted average shares outstanding158 157 150 
Effect of potentially dilutive common shares from:
Equity awards — 
Weighted average shares used in calculating diluted (loss) earnings per share158 157 151 
Antidilutive shares:
Convertible senior notes1 — 
Equity awards3 — 
Potentially dilutive shares excluded from calculation due to antidilutive effect4 — 
Schedule of Estimated Useful Lives of Major Classes of Property and Equipment
The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years
Property and Equipment
In millionsDecember 31,
2023
January 1,
2023
Leasehold improvements$803 $759 
Machinery and equipment684 644 
Computer hardware and software463 424 
Furniture and fixtures55 50 
Buildings44 44 
Construction in progress96 132 
Total property and equipment, gross2,145 2,053 
Accumulated depreciation(1,138)(962)
Total property and equipment, net$1,007 $1,091 
v3.24.0.1
Revenue (Tables)
12 Months Ended
Dec. 31, 2023
Revenue from Contract with Customer [Abstract]  
Schedule of Disaggregation of Revenue
Revenue by Source
202320222021
In millionsSequencingMicroarrayTotalSequencingMicroarrayTotalSequencingMicroarrayTotal
Consumables$2,790 $293 $3,083 $2,919 $306 $3,225 $2,911 $306 $3,217 
Instruments685 19 704 709 19 728 734 17 751 
Total product revenue3,475 312 3,787 3,628 325 3,953 3,645 323 3,968 
Service and other revenue637 80 717 543 88 631 464 94 558 
Total revenue$4,112 $392 $4,504 $4,171 $413 $4,584 $4,109 $417 $4,526 
Revenue by Geographic Area

Based on region of destination (in millions)2023
2022 (1)
2021 (1)
Americas (2)
$2,521 $2,479 $2,358 
Europe1,140 1,089 1,149 
Greater China (3)
384 472 502 
Asia-Pacific, Middle East and Africa (4)
459 544 517 
Total revenue$4,504 $4,584 $4,526 
_____________
(1)We implemented a new global commercial structure in Q1 2023 to improve operating efficiencies and better align with local markets. We integrated Asia-Pacific and Japan with emerging markets across the Middle East, Africa, Turkey, and Commonwealth of Independent States (CIS). Beginning in Q1 2023, and going forward, we will report regional results for the following regions: Americas, Europe, Greater China, and Asia-Pacific, Middle East and Africa (AMEA). Prior period amounts have been reclassified to conform to this new presentation.
(2)Americas revenue included United States revenue of $2,359 million, $2,290 million, and $2,195 million in 2023, 2022, and 2021, respectively.
(3)Region includes revenue from China, Taiwan, and Hong Kong.
(4)Region includes revenue from Russia and Turkey.
v3.24.0.1
Investments and Fair Value Measurements (Tables)
12 Months Ended
Dec. 31, 2023
Fair Value Disclosures [Abstract]  
Schedule of Marketable Securities
Gains and losses recognized in other (expense) income, net on our marketable equity securities were as follows:
In millions202320222021
Net (losses) recognized during the period on marketable equity securities$(2)$(81)$(52)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period(2)— (89)
Net unrealized (losses) gains recognized during the period on marketable equity securities still held at the reporting date$ $(81)$37 
Schedule of Fair Value Hierarchy for Assets and Liabilities Measured at Fair Value on a Recurring Basis
The following table presents the hierarchy for assets and liabilities measured at fair value on a recurring basis:

December 31, 2023January 1, 2023
In millionsLevel 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets:
Money market funds (cash equivalents)$774 $ $ $774 $1,642 $— $— $1,642 
Marketable equity securities6   6 26 — — 26 
Helix contingent value right  68 68 — — 58 58 
Deferred compensation plan assets 61  61 — 52 — 52 
Total assets measured at fair value$780 $61 $68 $909 $1,668 $52 $58 $1,778 
Liabilities:
Contingent consideration liabilities$ $ $387 $387 $— $— $412 $412 
Deferred compensation plan liability 59  59 — 51 — 51 
Total liabilities measured at fair value$ $59 $387 $446 $— $51 $412 $463 
Schedule of Changes in Estimated Fair Value of Acquisition Related Contingent Consideration Liabilities
Changes in the fair value of the Helix contingent value right, included in other (expense) income, net were as follows:

In millions
Balance as of January 3, 2021$35 
Change in estimated fair value30 
Balance as of January 2, 202265 
Change in estimated fair value(7)
Balance as of January 1, 202358 
Change in estimated fair value10 
Balance as of December 31, 2023$68 
Changes in the estimated fair value of our contingent consideration liabilities were as follows:

In millions
Balance as of January 3, 2021$— 
Acquisition of GRAIL762 
Other acquisition14 
Measurement period adjustment related to GRAIL acquisition(5)
Cash payments(15)
Exchange of GRAIL contingent value rights(145)
Change in estimated fair value
Balance as of January 2, 2022615 
Acquisition
Change in estimated fair value(205)
Balance as of January 1, 2023412 
Change in estimated fair value(24)
Cash payments(1)
Balance as of December 31, 2023$387 
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets (Tables)
12 Months Ended
Dec. 31, 2023
Business Combination And Goodwill And Intangible Assets [Abstract]  
Schedule of Total Purchase Price
The total purchase price consisted of the following:

In millionsAs Adjusted
Cash$2,862 
Fair value of common stock issued4,975 
Fair value of contingent consideration757 
Fair value of previously held investment1,149 
Settlement of preexisting relationships
Total purchase price$9,745 
Schedule of Preliminary Fair Value of Assets Acquired and Liabilities Assumed The fair values of assets acquired and liabilities assumed were:
In millionsAs Initially ReportedMeasurement Period AdjustmentsAs Adjusted
Cash and cash equivalents$571 $— $571 
Property and equipment89 — 89 
Operating lease right-of-use assets121 — 121 
Goodwill6,082 6,091 
Intangible assets3,180 (60)3,120 
Other current and noncurrent assets35 — 35 
Deferred tax liability(82)46 (36)
Long-term lease liabilities(97)— (97)
Other current and noncurrent liabilities(148)(1)(149)
Total net assets acquired$9,751 $(6)$9,745 
Schedule of Finite-Lived and Indefinite-Lived Intangible Assets Acquired as Part of Business Combination
The fair values assigned to identifiable intangible assets acquired were as follows:

In millions, except yearsFair Value
(as adjusted)
Estimated Useful Life
Developed technology$2,410 18
Trade name40 9
In-process research and development (IPR&D)670 Indefinite
Total intangible assets$3,120 
Schedule of Goodwill
Goodwill
In millions
Balance as of January 2, 2022$7,113 
Impairment(3,914)
Acquisition45 
Measurement period adjustments(5)
Balance as of January 1, 20233,239 
Impairment(712)
Acquisition18 
Balance as of December 31, 2023$2,545 
Schedule of Finite-lived Intangible Assets
Intangible Assets
 December 31, 2023January 1, 2023
In millionsGross
Carrying
Amount
Accumulated
Amortization
ImpairmentIntangible Assets,
Net
Gross
Carrying
Amount
Accumulated
Amortization
Intangible Assets,
Net
Developed technologies$2,807 $(585)$ $2,222 $2,812 $(449)$2,363 
Licensed technologies274 (133) 141 274 (105)169 
Trade name43 (14) 29 44 (10)34 
Customer relationships14 (13) 1 31 (29)
License agreements14 (13) 1 15 (14)
Database12 (3) 9 12 (1)11 
Total finite-lived intangible assets, net3,164 (761) 2,403 3,188 (608)2,580 
In-process research and development (IPR&D)705  (115)590 705 — 705 
Total intangible assets, net$3,869 $(761)$(115)$2,993 $3,893 $(608)$3,285 
Schedule of Estimated Annual Amortization of Finite-lived Intangible Assets
The estimated future annual amortization of finite-lived intangible assets is shown in the following table. Actual amortization expense to be reported in future periods could differ from these estimates as a result of acquisitions, divestitures, and asset impairments, among other factors.
In millionsEstimated Annual Amortization
2024$197 
2025197 
2026185 
2027183 
2028180 
Thereafter1,461 
Total$2,403 
v3.24.0.1
Debt and Other Commitments (Tables)
12 Months Ended
Dec. 31, 2023
Debt Disclosure [Abstract]  
Schedule of Debt Obligations
Summary of Term Debt Obligations
In millionsDecember 31,
2023
January 1,
2023
Principal amount of 2031 Term Notes outstanding$500 $500 
Principal amount of 2027 Term Notes outstanding500 500 
Principal amount of 2025 Term Notes outstanding500 500 
Principal amount of 2023 Term Notes outstanding 500 
Unamortized discounts and debt issuance costs(11)(13)
Net carrying amount of term notes1,489 1,987 
Less: current portion (500)
Term notes, non-current$1,489 $1,487 
Fair value of term notes outstanding (Level 2)$1,440 $1,913 
Schedule of Leases
As of December 31, 2023, the maturities of our operating lease liabilities were as follows:
In millions
2024$117
2025117
2026115
2027107
202889
Thereafter385
Total remaining lease payments (1)
930
Less: imputed interest(157)
Total operating lease liabilities773
Less: current portion(86)
Long-term operating lease liabilities$687
Weighted-average remaining lease term8.8 years
Weighted-average discount rate4.2 %
_____________
(1)Total remaining lease payments exclude $60 million of legally binding minimum lease payments for leases signed but not yet commenced.
Schedule of Components of Lease Costs
The components of our lease costs were as follows:
In millions202320222021
Operating lease costs
$116 $112 $99 
Sublease income(20)(20)(16)
Variable lease costs (1)
27 20 21 
Total lease costs$123 $112 $104 
_____________
(1)Variable lease costs include non-fixed maintenance charges and property taxes.
v3.24.0.1
Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2023
Equity [Abstract]  
Schedule of Restricted Stock Activity and Related Information, Restricted Stock
Restricted stock activity was as follows:
Restricted
Stock Units
(RSU) (1)
Performance
Stock Units
(PSU) (2)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 3, 20211,721 — $313.35 $— 
Awarded259 456 $438.46 $471.63 
Vested(606)(72)$303.08 $492.55 
Cancelled(244)(56)$321.93 $475.38 
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987) $268.08 $ 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
_____________
(1)In connection with the GRAIL acquisition, replacement awards of 59,000 RSU were awarded to GRAIL employees in 2021.
(2)The number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. As of December 31, 2023, there were approximately 129,000 rTSR PSU granted. Awarded units are presented net of performance adjustments.
Schedule of Restricted Stock Activity and Related Information, Performance Units
Restricted stock activity was as follows:
Restricted
Stock Units
(RSU) (1)
Performance
Stock Units
(PSU) (2)
Weighted-Average Grant-
Date Fair Value per Share
Units in thousandsRSUPSU
Outstanding at January 3, 20211,721 — $313.35 $— 
Awarded259 456 $438.46 $471.63 
Vested(606)(72)$303.08 $492.55 
Cancelled(244)(56)$321.93 $475.38 
Outstanding at January 2, 20221,130 328 $345.66 $466.42 
Awarded1,370 (108)$302.52 $479.85 
Vested(707)(99)$341.56 $492.55 
Cancelled(182)(47)$341.14 $411.78 
Outstanding at January 1, 20231,611 74 $311.23 $446.74 
Awarded2,032 39 $195.94 $239.98 
Vested(987) $268.08 $ 
Cancelled(458)(113)$253.52 $299.98 
Outstanding at December 31, 20232,198  $236.32 $ 
_____________
(1)In connection with the GRAIL acquisition, replacement awards of 59,000 RSU were awarded to GRAIL employees in 2021.
(2)The number of units reflect the estimated number of shares to be issued at the end of the performance period. For rTSR PSU, the number of units reflect the estimated number of shares to be issued based on performance as of the current reporting period. As of December 31, 2023, there were approximately 129,000 rTSR PSU granted. Awarded units are presented net of performance adjustments.
Schedule of Pre-tax Intrinsic Values of Vested Restricted Stock
Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202320222021
Pre-tax intrinsic value of outstanding restricted stock:
RSU$306 $326 $430 
PSU$ $15 $125 
Fair value of restricted stock vested:
RSU$122 $162 $247 
PSU$ $49 $35 
Liability- Classified RSU

In Q1 2023, we granted RSU that were to be settled in cash if stockholder approval to increase our share reserve under the amended and restated 2015 Stock Plan was not obtained. In Q2 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance. Upon such approval, all RSU previously accounted for as liability-classified awards, approximately 557,000 RSU, were reclassified to stockholders equity and accounted for prospectively as equity awards. There were no RSU liability-classified awards outstanding as of December 31, 2023.
Schedule of Total Fair Value of Vested Restricted Stock
Pre-tax intrinsic value and fair value of vested restricted stock was as follows:
In millions202320222021
Pre-tax intrinsic value of outstanding restricted stock:
RSU$306 $326 $430 
PSU$ $15 $125 
Fair value of restricted stock vested:
RSU$122 $162 $247 
PSU$ $49 $35 
Liability- Classified RSU

In Q1 2023, we granted RSU that were to be settled in cash if stockholder approval to increase our share reserve under the amended and restated 2015 Stock Plan was not obtained. In Q2 2023, the Company’s stockholders approved an amended and restated version of the 2015 Stock Plan and increased the maximum number of shares authorized for issuance. Upon such approval, all RSU previously accounted for as liability-classified awards, approximately 557,000 RSU, were reclassified to stockholders equity and accounted for prospectively as equity awards. There were no RSU liability-classified awards outstanding as of December 31, 2023.
Schedule of Stock Option Activity Under all Stock Option Plans
Stock option activity was as follows:
Units in thousandsOptionsWeighted-Average
Exercise Price
Performance Stock Options(1)
Weighted-Average
Exercise Price
Outstanding at January 3, 202110 $59.11 — $— 
Granted— $— 48 $86.73 
Exercised(2)$20.06 (21)$86.72 
Cancelled— $— (10)$89.63 
Outstanding at January 2, 2022$66.42 17 $85.54 
Granted180 $330.25 — $— 
Exercised(1)$6.55 — $— 
Outstanding at January 1, 2023187 $319.72 17 $85.54 
Exercised(8)$71.09 (1)$16.69 
Cancelled(144)$330.25  $ 
Outstanding at December 31, 202335 $330.25 16 $87.74 
Exercisable at December 31, 20239 $330.25  $ 
_____________
(1)In connection with the GRAIL acquisition, we issued replacement performance stock options to GRAIL employees in 2021. The number of units reflect awards that have been granted and for which it is assumed to be probable that the underlying performance goals will be achieved.
Schedule of Cash-Based Equity Incentive Award Activity
Cash-based equity incentive award activity was as follows:

In millions
Outstanding at January 3, 2021$— 
Granted218 
Cancelled(42)
Change in fair value
Outstanding at January 2, 2022184 
Granted168 
Vested and paid in cash(41)
Cancelled(41)
Change in fair value23 
Outstanding at January 1, 2023293 
Granted116 
Vested and paid in cash(77)
Cancelled(32)
Change in fair value(8)
Outstanding at December 31, 2023$292 
Estimated liability as of December 31, 2023 (included in accrued liabilities)$55 
Schedule of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan
The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the ESPP were as follows:
202320222021
Risk-free interest rate
0.78% - 5.54%
 0.06% - 2.98%
0.06% - 0.12%
Expected volatility
41% - 51%
 37% - 51%
37% - 47%
Expected term
0.5 - 1.1 years
 0.5 - 1.0 year
0.5 - 1.0 year
Expected dividends
0%
0%0%
Weighted-average grant-date fair value per share$49.87 $50.22 $134.47 
Schedule of Share-Based Compensation Expense for all Stock Awards
Share-based compensation expense, which includes expense for both equity and liability-classified awards, reported in our consolidated statements of operations was as follows:

In millions202320222021
Cost of product revenue$29 $26 $23 
Cost of service and other revenue7 
Research and development155 153 276 
Selling, general and administrative189 181 638 
Share-based compensation expense, before taxes380 366 941 
Related income tax benefits(87)(83)(64)
Share-based compensation expense, net of taxes$293 $283 $877 
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details (Tables)
12 Months Ended
Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Accounts Receivable
Accounts Receivable
In millionsDecember 31,
2023
January 1,
2023
Trade accounts receivable, gross$741 $675 
Allowance for credit losses(7)(4)
Total accounts receivable, net$734 $671 
Schedule of Inventory
Inventory
In millionsDecember 31,
2023
January 1,
2023
Raw materials$276 $247 
Work in process402 386 
Finished goods30 28 
Inventory, gross708 661 
Inventory reserve(121)(93)
Total inventory, net$587 $568 
Schedule of Property and Equipment
The estimated useful lives of the major classes of property and equipment are generally as follows:
Buildings and leasehold improvements
4 to 20 years
Machinery and equipment
3 to 5 years
Computer hardware and software
3 to 9 years
Furniture and fixtures
7 years
Property and Equipment
In millionsDecember 31,
2023
January 1,
2023
Leasehold improvements$803 $759 
Machinery and equipment684 644 
Computer hardware and software463 424 
Furniture and fixtures55 50 
Buildings44 44 
Construction in progress96 132 
Total property and equipment, gross2,145 2,053 
Accumulated depreciation(1,138)(962)
Total property and equipment, net$1,007 $1,091 
Schedule of Accrued Liabilities
Accrued Liabilities
In millionsDecember 31,
2023
January 1,
2023
Legal contingencies(1)
$484 $473 
Contract liabilities, current portion252 245 
Accrued compensation expenses(2)
223 188 
Accrued taxes payable79 97 
Operating lease liabilities, current portion86 76 
Liability-classified equity incentive awards55 36 
Other, including warranties(3)
146 117 
Total accrued liabilities$1,325 $1,232 
_____________
(1)See note “8. Legal Proceedings” for additional details.
(2)Included employee separation costs related to restructuring activities.
(3)See table below for changes in the reserve for product warranties.
Schedule of Changes in Reserve for Product Warranties
Changes in the reserve for product warranties were as follows:
In millions
Balance as of January 3, 2021$13 
Additions charged to cost of product revenue33 
Repairs and replacements(24)
Balance as of January 2, 202222 
Additions charged to cost of product revenue23 
Repairs and replacements(27)
Balance as of January 1, 202318 
Additions charged to cost of product revenue42 
Repairs and replacements(39)
Balance as of December 31, 2023$21 
Schedule of Restructuring and Related Costs
A summary of the pre-tax restructuring charges recorded in 2023 are as follows:

In millions
Employee separation costs$48 
Asset impairment charges (1)
100 
Other costs
Total restructuring charges (2)
$152 
_____________
(1)Primarily related to impairment of right-of-use assets and leasehold improvements for our i3 and Foster City campuses in California.
(2)For 2023, $122 million was recorded in SG&A expense, $24 million in R&D expense, with the remainder recorded in cost of revenue. These restructuring activities primarily relate to our Core Illumina segment.
A summary of the restructuring liability is as follows:

In millions
Employee Separation Costs (1)
Other CostsTotal
Expense recorded in 2023$48 $$52 
Cash paid during 2023(31)(3)(34)
Amount recorded in accrued liabilities as of YTD 2023
$17 $$18 
Estimated total restructuring costs to still be incurred
$$— $
_____________
(1)It is expected that substantially all of the employee separation related restructuring charges will be incurred and paid by the end of Q1 2024.
Schedule of Other Nonoperating Income (Expense)
Other (Expense) Income, Net

In millions202320222021
Gain on previously held investment in GRAIL$ $— $899 
Gain on exchange of GRAIL contingent value rights — 86 
Gain (loss) on Helix contingent value right10 (7)30 
Gain on derivative assets related to terminated acquisition — 26 
(Losses) gains on strategic investments, net(40)(122)18 
Other1 (13)
Other (expense) income, net$(29)$(142)$1,068 
v3.24.0.1
Income Taxes (Tables)
12 Months Ended
Dec. 31, 2023
Income Tax Disclosure [Abstract]  
Schedule of (Loss) Income before Income Taxes by Region
(Loss) income before income taxes summarized by region was as follows:
In millions202320222021
United States$(1,735)$(4,942)$(115)
Foreign618 606 999 
Total (loss) income before income taxes$(1,117)$(4,336)$884 
Schedule of Provision for Income Taxes
The provision for income taxes consisted of the following:
In millions202320222021
Current:   
Federal$(5)$(11)$54 
State6 27 37 
Foreign77 75 107 
Total current provision78 91 198 
Deferred:
Federal(13)40 (50)
State(26)(47)(23)
Foreign5 (16)(3)
Total deferred benefit(34)(23)(76)
Total tax provision$44 $68 $122 
Schedule of Reconciliation of Provision for (Loss) Income Taxes to Amount Computed by Applying the Federal Statutory Rate
The provision for income taxes reconciles to the amount computed by applying the federal statutory rate to (loss) income before taxes as follows:
In millions202320222021
Tax at federal statutory rate$(235)$(911)$186 
State, net of federal benefit(16)(9)13 
Research and other credits(42)(46)(23)
Change in valuation allowance48 62 33 
Impact of R&D expense capitalization86 87 — 
Impact of net operating losses on GILTI and U.S. foreign tax credits61 60 — 
Impact of foreign operations(50)(81)(80)
Impact of foreign derived intangible income (FDII) deduction1 (1)(12)
Stock compensation31 20 (10)
Officer compensation(4)13 
Accrual of European Commission fine3 96 — 
Goodwill impairment149 822 — 
Impact of acquisition related items8 (27)(16)
Other4 (8)18 
Total tax provision$44 $68 $122 
Schedule of Significant Components of Deferred Tax Assets and Liabilities
Significant components of deferred tax assets and liabilities were as follows:
In millionsDecember 31,
2023
January 1,
2023
Deferred tax assets:  
Net operating losses$392 $408 
Tax credits211 157 
Other accruals and reserves49 40 
Stock compensation15 20 
Capitalized U.S. R&D expenses158 97 
Other amortization115 247 
Operating lease liabilities146 156 
Property and equipment4 — 
Investments7 
Other56 38 
Total gross deferred tax assets1,153 1,168 
Valuation allowance on deferred tax assets(251)(203)
Total deferred tax assets
902 965 
Deferred tax liabilities:  
Purchased intangible amortization(734)(800)
Property and equipment (11)
Operating lease right-of-use assets(88)(112)
Other(25)(18)
Total deferred tax liabilities(847)(941)
Deferred tax assets, net$55 $24 
Schedule of the Gross Amount of Uncertain Tax Positions
The following table summarizes the gross amount of our uncertain tax positions:
In millionsDecember 31,
2023
January 1,
2023
January 2,
2022
Balance at beginning of year$153 $131 $80 
Increases related to prior year tax positions27 12 19 
Decreases related to prior year tax positions(2)(3)(1)
Increases related to current year tax positions42 42 39 
Decreases related to lapse of statute of limitations(10)(29)(6)
Balance at end of year$210 $153 $131 
v3.24.0.1
Segments and Geographic Data (Tables)
12 Months Ended
Dec. 31, 2023
Segment Reporting [Abstract]  
Schedule of Operating Performance and Assets by Segment
 In millions202320222021
Revenue:
Core Illumina$4,438 $4,553 $4,519 
GRAIL93 55 12 
Eliminations(27)(24)(5)
Consolidated revenue$4,504 $4,584 $4,526 
Depreciation and amortization:
Core Illumina$273 $240 $200 
GRAIL159 154 51 
Consolidated depreciation and amortization$432 $394 $251 
Income (loss) from operations:
Core Illumina$552 $481 $808 
GRAIL(1,621)(4,657)(931)
Eliminations (3)— 
Consolidated (loss) income from operations$(1,069)$(4,179)$(123)
Capital expenditures:
Core Illumina$183 $262 $201 
GRAIL13 24 
Eliminations(1)— (1)
Consolidated capital expenditures$195 $286 $208 

Total other (expense) income, net primarily relates to Core Illumina and we do not allocate income taxes to our segments.
Schedule of Net Long-lived Assets Consisting of Property and Equipment by Region
Net long-lived assets, consisting of property and equipment and operating lease right-of-use assets, by region, were as follows:
In millionsDecember 31,
2023
January 1,
2023
United States$1,040 $1,237 
Singapore298 290 
United Kingdom136 149 
Other countries77 68 
Total net long-lived assets$1,551 $1,744 
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Concentrations of Risk (Details)
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Credit Concentration Risk | Investment Portfolio      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 5.00%    
Credit Concentration Risk | Issue Size      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 5.00%    
Industry Credit Concentration Risk | Investment Portfolio      
Concentration Risk [Line Items]      
Maximum investment portfolio credit exposure 30.00%    
Outside the United States | Geographic Concentration Risk | Sales Revenue, Net      
Concentration Risk [Line Items]      
Concentration percent 48.00% 50.00% 52.00%
Outside the United States | Geographic Concentration Risk | Accounts Receivable      
Concentration Risk [Line Items]      
Concentration percent 55.00% 54.00%  
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Recently Adopted Accounting Policies (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Jan. 03, 2022
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Retained earnings (accumulated deficit) $ (19) $ 1,142  
Additional paid-in capital $ (9,555) $ (9,207)  
ASU 2020-06 | Cumulative Effect, Period of Adoption, Adjustment      
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Convertible debt     $ 43
Retained earnings (accumulated deficit)     61
Deferred tax assets, net     11
Additional paid-in capital     $ 93
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Revenue Recognition (Details)
12 Months Ended
Dec. 31, 2023
Product revenue  
Revenue from External Customer [Line Items]  
Payment period from invoice 30 days
v3.24.0.1
Organization and Significant Accounting Policies - Schedule of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings (Loss) Per Share (Details) - shares
shares in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Accounting Policies [Abstract]      
Weighted average shares outstanding (in shares) 158 157 150
Effect of potentially dilutive common shares from:      
Equity awards (in shares) 0 0 1
Weighted average shares used in calculating diluted earnings (loss) per share (in shares) 158 157 151
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded from calculation due to antidilutive effect (in shares) 4 4 0
Diluted (in shares) 158 157 151
Convertible senior notes      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded from calculation due to antidilutive effect (in shares) 1 2 0
Equity awards      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares excluded from calculation due to antidilutive effect (in shares) 3 2 0
v3.24.0.1
Organization and Significant Accounting Policies - Schedule of Estimated Useful Lives of Major Classes of Property and Equipment (Details)
Dec. 31, 2023
Buildings and leasehold improvements | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 4 years
Buildings and leasehold improvements | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 20 years
Machinery and equipment | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 3 years
Machinery and equipment | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 5 years
Computer hardware and software | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 3 years
Computer hardware and software | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 9 years
Furniture and fixtures | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 7 years
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Leases (Details)
ft² in Millions
Dec. 31, 2023
ft²
Property, Plant and Equipment [Line Items]  
Lessee operating lease, area 2.8
Minimum  
Property, Plant and Equipment [Line Items]  
Lessee, operating lease, remaining lease term 1 year
Lessee, operating lease, renewal term 2 years
Maximum  
Property, Plant and Equipment [Line Items]  
Lessee, operating lease, remaining lease term 15 years
Lessee, operating lease, renewal term 20 years
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Derivative Financial Instruments (Details)
€ in Millions, $ in Millions
12 Months Ended
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Jan. 02, 2022
USD ($)
Jul. 25, 2023
EUR (€)
Jul. 12, 2023
EUR (€)
Derivative Instruments, Gain (Loss) [Line Items]          
Derivative term 24 months        
Other comprehensive income (loss) hedge $ 18 $ 53 $ 10    
GRAIL          
Derivative Instruments, Gain (Loss) [Line Items]          
Loss contingency accrual 484     € 432 € 432
Foreign Exchange Forward          
Derivative Instruments, Gain (Loss) [Line Items]          
Derivative assets related to terminated acquisition 5 8      
Derivative liabilities related to terminated acquisition 9 6      
Foreign Exchange Forward | Not Designated as Hedging Instrument          
Derivative Instruments, Gain (Loss) [Line Items]          
Notional amount of outstanding forward contracts 926 485      
Foreign Exchange Forward | Designated as Hedging Instrument          
Derivative Instruments, Gain (Loss) [Line Items]          
Notional amount of outstanding forward contracts $ 628 $ 425      
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Warranties (Details)
12 Months Ended
Dec. 31, 2023
Instruments  
Product Warranty Liability [Line Items]  
Warranty period 1 year
Consumables | Minimum  
Product Warranty Liability [Line Items]  
Warranty period 6 months
Consumables | Maximum  
Product Warranty Liability [Line Items]  
Warranty period 12 months
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Share-Based Compensation (Details)
12 Months Ended
Dec. 31, 2023
Accounting Policies [Abstract]  
Expected dividend yield 0.00%
v3.24.0.1
Organization and Significant Accounting Policies - Narrative - Advertising Costs (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Accounting Policies [Abstract]      
Advertising costs $ 36 $ 53 $ 48
v3.24.0.1
Revenue - Schedule of Disaggregation of Revenue (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Revenue from External Customer [Line Items]      
Revenue $ 4,504 $ 4,584 $ 4,526
Americas      
Revenue from External Customer [Line Items]      
Revenue 2,521 2,479 2,358
Europe      
Revenue from External Customer [Line Items]      
Revenue 1,140 1,089 1,149
Greater China      
Revenue from External Customer [Line Items]      
Revenue 384 472 502
Asia-Pacific, Middle East and Africa      
Revenue from External Customer [Line Items]      
Revenue 459 544 517
United States      
Revenue from External Customer [Line Items]      
Revenue 2,359 2,290 2,195
Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 3,787 3,953 3,968
Consumables      
Revenue from External Customer [Line Items]      
Revenue 3,083 3,225 3,217
Instruments      
Revenue from External Customer [Line Items]      
Revenue 704 728 751
Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue 717 631 558
Sequencing      
Revenue from External Customer [Line Items]      
Revenue 4,112 4,171 4,109
Sequencing | Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 3,475 3,628 3,645
Sequencing | Consumables      
Revenue from External Customer [Line Items]      
Revenue 2,790 2,919 2,911
Sequencing | Instruments      
Revenue from External Customer [Line Items]      
Revenue 685 709 734
Sequencing | Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue 637 543 464
Microarray      
Revenue from External Customer [Line Items]      
Revenue 392 413 417
Microarray | Total product revenue      
Revenue from External Customer [Line Items]      
Revenue 312 325 323
Microarray | Consumables      
Revenue from External Customer [Line Items]      
Revenue 293 306 306
Microarray | Instruments      
Revenue from External Customer [Line Items]      
Revenue 19 19 17
Microarray | Service and other revenue      
Revenue from External Customer [Line Items]      
Revenue $ 80 $ 88 $ 94
v3.24.0.1
Revenue - Narrative - Remaining Performance Obligation (Details)
$ in Millions
12 Months Ended
Dec. 31, 2023
USD ($)
Revenue from Contract with Customer [Abstract]  
Remaining performance obligation $ 653
Minimum  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Product or service delivery period 3 months
Maximum  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Product or service delivery period 6 months
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-01-01  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Percent of remaining performance obligation 82.00%
Revenue, remaining performance obligation, expected timing of satisfaction, period 12 months
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-12-30  
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]  
Percent of remaining performance obligation 13.00%
Revenue, remaining performance obligation, expected timing of satisfaction, period 12 months
v3.24.0.1
Revenue - Narrative - Contract Assets and Liabilities (Details) - USD ($)
$ in Millions
12 Months Ended
Jan. 01, 2023
Dec. 31, 2023
Revenue from Contract with Customer [Abstract]    
Contract asset $ 17 $ 18
Contract liability 308 329
Contract liabilities, current portion 245 $ 252
Revenue recognized, previously deferred $ 235  
v3.24.0.1
Investments and Fair Value Measurements - Narrative (Details)
$ in Thousands, shares in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 18, 2021
USD ($)
Dec. 31, 2021
USD ($)
shares
Apr. 30, 2019
Oct. 01, 2023
USD ($)
Oct. 02, 2022
USD ($)
Jan. 02, 2022
USD ($)
Jul. 04, 2021
USD ($)
Dec. 31, 2023
USD ($)
venture
Jan. 01, 2023
USD ($)
Jan. 02, 2022
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Marketable equity securities               $ 6,000 $ 26,000  
Strategic equity investments, without readily determinable fair values               28,000 28,000  
Revenue               4,504,000 4,584,000 $ 4,526,000
Gain on exchange of GRAIL contingent value rights               0 0 86,000
Business combination, contingent consideration arrangements, change in amount of contingent consideration, liability               24,000 205,000 (4,000)
Helix Holdings I, LLC                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Contingent value right, terms     7 years              
Business Combination, Contingent Consideration, Liability                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Cash payments           $ 15,000   (1,000)   (15,000)
Investee                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Revenue               69,000 113,000 74,000
GRAIL Inc                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Contingent value right, terms 12 years                  
Covered revenues of GRAIL       $ 85,000 $ 42,000          
Payment for contingent consideration   $ 57,000           803 396  
Contingent consideration liabilities   $ 145,000           387,000 412,000  
Contingent consideration, noncurrent               $ 385,000 411,000  
Contingent value rights exchanged (in shares) | shares   73                
Number of shares issued in exchange for contingent consideration | shares   2                
Gain on exchange of GRAIL contingent value rights   $ 86,000                
Business combination, consideration transferred for contingent consideration transferred   $ 59,000                
Fair value of contingent consideration $ 757,000                  
GRAIL Inc | Payment Rights Of One Billion Each Twelve Years                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Contingent payment rights, first percentage 2.50%                  
Business acquisition, contingent value rights, revenue threshold $ 1,000,000                  
GRAIL Inc | Payment Rights Of Above One Billion Each Twelve Years                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Business acquisition, contingent value rights, revenue threshold $ 1,000,000                  
Contingent payment rights, second percentage 9.00%                  
Series of Individually Immaterial Business Acquisitions                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Fair value of contingent consideration             $ 14,000      
Business combination, contingent consideration arrangements, change in amount of contingent consideration, liability                   1,000
Venture Capital Investment Fund (the Fund)                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Number of venture capital investment funds | venture               2    
Equity method investments               $ 168,000 183,000  
Unrealized gain (loss) on equity method investments               (33,000) $ (25,000) $ 55,000
Venture Capital Investment Fund (the Funds), One                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Commitment in new venture capital investment fund               100,000    
Remaining capital commitment               4,000    
Venture Capital Investment Fund (the Funds), Two                    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                    
Commitment in new venture capital investment fund               150,000    
Remaining capital commitment               $ 71,000    
v3.24.0.1
Investments and Fair Value Measurements - Schedule of Marketable Equity Securities (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Marketable Securities, Gain (Loss) [Abstract]      
Net (losses) recognized during the period on marketable equity securities $ (2) $ (81) $ (52)
Less: Net (losses) recognized during the period on marketable equity securities sold during the period (2) 0 (89)
Net unrealized (losses) gains recognized during the period on marketable equity securities still held at the reporting date $ 0 $ (81) $ 37
v3.24.0.1
Investments and Fair Value Measurements - Schedule of Hierarchy for Assets and Liabilities Measured at Fair Value Recurring Basis (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Assets:    
Marketable equity securities $ 6 $ 26
Fair value, Measurements, Recurring    
Assets:    
Money market funds (cash equivalents) 774 1,642
Marketable equity securities 6 26
Helix contingent value right 68 58
Deferred compensation plan assets 61 52
Total assets measured at fair value 909 1,778
Liabilities:    
Contingent consideration liabilities 387 412
Deferred compensation plan liability 59 51
Total liabilities measured at fair value 446 463
Fair value, Measurements, Recurring | Level 1    
Assets:    
Money market funds (cash equivalents) 774 1,642
Marketable equity securities 6 26
Helix contingent value right 0 0
Deferred compensation plan assets 0 0
Total assets measured at fair value 780 1,668
Liabilities:    
Contingent consideration liabilities 0 0
Deferred compensation plan liability 0 0
Total liabilities measured at fair value 0 0
Fair value, Measurements, Recurring | Level 2    
Assets:    
Money market funds (cash equivalents) 0 0
Marketable equity securities 0 0
Helix contingent value right 0 0
Deferred compensation plan assets 61 52
Total assets measured at fair value 61 52
Liabilities:    
Contingent consideration liabilities 0 0
Deferred compensation plan liability 59 51
Total liabilities measured at fair value 59 51
Fair value, Measurements, Recurring | Level 3    
Assets:    
Money market funds (cash equivalents) 0 0
Marketable equity securities 0 0
Helix contingent value right 68 58
Deferred compensation plan assets 0 0
Total assets measured at fair value 68 58
Liabilities:    
Contingent consideration liabilities 387 412
Deferred compensation plan liability 0 0
Total liabilities measured at fair value $ 387 $ 412
v3.24.0.1
Investments and Fair Value Measurements - Schedule of Changes in Estimated Fair Value of Acquisition Related Contingent Consideration Liabilities (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Jan. 02, 2022
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Helix Contingent Consideration        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]        
Beginning balance   $ 58 $ 65 $ 35
Change in estimated fair value   10 (7) 30
Ending balance $ 65 68 58 65
Business Combination, Contingent Consideration, Liability        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]        
Beginning balance   412 615 0
Acquisitions     2  
Measurement period adjustment related to GRAIL acquisition       (5)
Cash payments 15 (1)   (15)
Exchange of GRAIL contingent value rights       (145)
Change in estimated fair value   (24) (205) 4
Ending balance $ 615 $ 387 $ 412 615
Business Combination, Contingent Consideration, Liability | GRAIL Inc        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]        
Acquisitions       762
Business Combination, Contingent Consideration, Liability | Other Acquisition        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]        
Acquisitions       $ 14
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Narrative (Details)
shares in Millions, $ in Millions
3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended 28 Months Ended
Aug. 18, 2021
USD ($)
shares
Aug. 17, 2021
USD ($)
Dec. 31, 2023
USD ($)
Oct. 01, 2023
USD ($)
Oct. 02, 2022
USD ($)
Jul. 04, 2021
USD ($)
Jul. 02, 2023
USD ($)
unit
Oct. 01, 2023
USD ($)
Oct. 02, 2022
USD ($)
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Jan. 02, 2022
USD ($)
Dec. 31, 2023
USD ($)
Goodwill [Line Items]                          
Gain on previously held investment in GRAIL                   $ 0 $ 0 $ 899  
Goodwill, purchase accounting adjustments                     5    
Number of reporting units | unit             2            
Goodwill and intangible impairment     $ 712             827 3,914 0  
Goodwill     2,545             2,545 3,239 7,113 $ 2,545
GRAIL                          
Goodwill [Line Items]                          
Goodwill, purchase accounting adjustments         $ 6                
Deferred tax assets         $ 6                
Goodwill and intangible impairment       $ 3,914       $ 712          
Fair value of discount rate (as a percent)       22.00%       24.00%          
Goodwill       $ 1,466       $ 1,466          
Core Illumina                          
Goodwill [Line Items]                          
Fair value in excess of carrying amount (more than)     30,000             $ 30,000     $ 30,000
Developed technology                          
Goodwill [Line Items]                          
Value of intangible assets acquired     $ 19       $ 23            
Weighted-average useful lives (in years)     10 years       7 years     18 years      
Database                          
Goodwill [Line Items]                          
Value of intangible assets acquired             $ 12            
Weighted-average useful lives (in years)             7 years            
License | Complete Genomics                          
Goodwill [Line Items]                          
License granted intangible assets                 $ 180 $ 180      
Finite-lived intangible assets, remaining amortization period     6 years 6 months   6 years 6 months       6 years 6 months 6 years 6 months     6 years 6 months
In-process research and development (IPR&D)                          
Goodwill [Line Items]                          
Fair value of discount rate (as a percent)               19.00%          
Goodwill fair value recorded impairment       6       $ 109   $ 115      
In-process research and development (IPR&D)     $ 590 $ 561       $ 561   590 $ 705   $ 590
GRAIL Inc                          
Goodwill [Line Items]                          
Business acquisition, common stock issued (in shares) | shares 9.8                        
Equity ownership percentage 12.00%                        
Equity investment $ 1,100                        
Gain on previously held investment in GRAIL                       899  
Purchase price related to fair value of equity awards attributable to pre-combination service 69                        
Share-based payment arrangement, accelerated cost                       615  
Fair value of replacement awards 48                        
Goodwill, purchase accounting adjustments                         (9)
Acquisition related costs                       156  
Business combination, continuation payments   $ 35                      
Fair value in excess of carrying amount (more than)     950             950     950
Business combination exceeding carrying values                   $ 19,000      
Business combination impairment test percentage                   23.00%      
Goodwill $ 6,082   $ 6,091             $ 6,091     $ 6,091
GRAIL Inc | Selling, general and administrative                          
Goodwill [Line Items]                          
Business combination, continuation payments                       $ 245  
Series of Individually Immaterial Business Acquisitions | In-process research and development (IPR&D)                          
Goodwill [Line Items]                          
Indefinite-lived intangible assets acquired           $ 35              
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Total Purchase Price (Details) - GRAIL Inc
$ in Millions
Aug. 18, 2021
USD ($)
Goodwill [Line Items]  
Cash $ 2,862
Fair value of common stock issued 4,975
Fair value of contingent consideration 757
Fair value of previously held investment 1,149
Settlement of preexisting relationships 2
Total purchase price $ 9,745
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Preliminary Fair Value of Assets Acquired and Liabilities Assumed (Details) - USD ($)
$ in Millions
12 Months Ended 28 Months Ended
Jan. 01, 2023
Dec. 31, 2023
Jan. 02, 2022
Aug. 18, 2021
Finite-Lived Intangible Assets [Line Items]        
Goodwill $ 3,239 $ 2,545 $ 7,113  
Measurement period adjustments $ (5)      
GRAIL Inc        
Finite-Lived Intangible Assets [Line Items]        
Cash and cash equivalents   571   $ 571
Property and equipment   89   89
Operating lease right-of-use assets   121   121
Goodwill   6,091   6,082
Measurement period adjustments   9    
Intangible assets   3,120   3,180
Measurement period adjustments, intangibles   (60)    
Other current and noncurrent assets   35   35
Deferred tax liability   (36)   (82)
Measurement period adjustments, deferred tax liability   46    
Long-term lease liabilities   (97)   (97)
Other current and noncurrent liabilities   (149)   (148)
Measurement period adjustments, other current and noncurrent liabilities   (1)    
Total net assets acquired   9,745   $ 9,751
Measurement period adjustments, Total net assets acquired   $ (6)    
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Amount Assigned to Identifiable Intangible Assets (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended 12 Months Ended
Dec. 31, 2023
Jul. 02, 2023
Dec. 31, 2023
Aug. 18, 2021
Developed technology        
Indefinite-lived Intangible Assets [Line Items]        
Useful life (in years) 10 years 7 years 18 years  
Trade name        
Indefinite-lived Intangible Assets [Line Items]        
Useful life (in years)     9 years  
GRAIL Inc        
Indefinite-lived Intangible Assets [Line Items]        
Total intangible assets $ 3,120   $ 3,120 $ 3,180
GRAIL Inc | In-process research and development (IPR&D)        
Indefinite-lived Intangible Assets [Line Items]        
Indefinite lived intangible assets acquired 670   670  
GRAIL Inc | Developed technology        
Indefinite-lived Intangible Assets [Line Items]        
Finite-lived intangible assets acquired 2,410   2,410  
GRAIL Inc | Trade name        
Indefinite-lived Intangible Assets [Line Items]        
Finite-lived intangible assets acquired $ 40   $ 40  
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Changes in Goodwill (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2023
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Goodwill [Roll Forward]        
Balance at beginning of period   $ 3,239 $ 7,113  
Impairment $ (712) (827) (3,914) $ 0
Acquisition   18 45  
Measurement period adjustments     (5)  
Balance at end of period $ 2,545 $ 2,545 $ 3,239 $ 7,113
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Identifiable Intangible Assets (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended 12 Months Ended
Oct. 01, 2023
Oct. 01, 2023
Dec. 31, 2023
Jan. 01, 2023
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     $ 3,164 $ 3,188
Accumulated Amortization     (761) (608)
Impairment     0  
Total intangible assets, net     2,403 2,580
Impairment of Intangible Assets (Excluding Goodwill)     (115)  
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Gross Carrying Amount     3,869 3,893
Accumulated Amortization     761 608
Intangible Assets, Net     $ 2,993 $ 3,285
Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration]     Goodwill and intangible impairment Goodwill and intangible impairment
Developed technologies        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     $ 2,807 $ 2,812
Accumulated Amortization     (585) (449)
Impairment     0  
Total intangible assets, net     2,222 2,363
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     585 449
Licensed technologies        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     274 274
Accumulated Amortization     (133) (105)
Impairment     0  
Total intangible assets, net     141 169
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     133 105
Trade name        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     43 44
Accumulated Amortization     (14) (10)
Impairment     0  
Total intangible assets, net     29 34
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     14 10
Customer relationships        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     14 31
Accumulated Amortization     (13) (29)
Impairment     0  
Total intangible assets, net     1 2
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     13 29
License agreements        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     14 15
Accumulated Amortization     (13) (14)
Impairment     0  
Total intangible assets, net     1 1
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     13 14
Database        
Finite-Lived Intangible Assets [Line Items]        
Gross Carrying Amount     12 12
Accumulated Amortization     (3) (1)
Impairment     0  
Total intangible assets, net     9 11
Intangible Assets, Net (Excluding Goodwill) [Abstract]        
Accumulated Amortization     3 1
In-process research and development (IPR&D)        
Finite-Lived Intangible Assets [Line Items]        
In-process research and development (IPR&D)     705  
Goodwill fair value recorded impairment $ (6) $ (109) (115)  
In-process research and development (IPR&D) $ 561 $ 561 $ 590 $ 705
v3.24.0.1
Acquisitions, Goodwill and Intangible Assets - Schedule of Estimated Annual Amortization of Intangible Assets (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Estimated Annual Amortization    
2024 $ 197  
2025 197  
2026 185  
2027 183  
2028 180  
Thereafter 1,461  
Total intangible assets, net $ 2,403 $ 2,580
v3.24.0.1
Debt and Other Commitments - Schedule of Debt Obligations (Details) - USD ($)
Dec. 31, 2023
Jan. 01, 2023
Dec. 13, 2022
Mar. 31, 2021
Mar. 23, 2021
Aug. 31, 2018
Term Notes            
Debt Instrument [Line Items]            
Unamortized discounts and debt issuance costs $ (11,000,000) $ (13,000,000)        
Net carrying amount of term notes 1,489,000,000 1,987,000,000        
Less: current portion 0 (500,000,000)        
Term notes, non-current 1,489,000,000 1,487,000,000        
Term Notes | Level 2            
Debt Instrument [Line Items]            
Fair value of term notes outstanding (Level 2) 1,440,000,000 1,913,000,000        
Term Notes | Term Notes Due 2031            
Debt Instrument [Line Items]            
Principal amount of notes outstanding 500,000,000 500,000,000     $ 500,000,000  
Term Notes | Term Notes Due 2027            
Debt Instrument [Line Items]            
Principal amount of notes outstanding 500,000,000 500,000,000 $ 500,000,000      
Term Notes | Term Notes Due 2025            
Debt Instrument [Line Items]            
Principal amount of notes outstanding 500,000,000 500,000,000 $ 500,000,000      
Term Notes | Term Notes Due 2023            
Debt Instrument [Line Items]            
Principal amount of notes outstanding $ 0 $ 500,000,000   $ 500,000,000    
Convertible Senior Notes | 2023 Notes            
Debt Instrument [Line Items]            
Principal amount of notes outstanding           $ 750,000,000
v3.24.0.1
Debt and Other Commitments - Narrative (Details)
1 Months Ended 12 Months Ended
Jan. 04, 2023
USD ($)
one_year_extension
Dec. 13, 2022
USD ($)
Mar. 23, 2021
USD ($)
Aug. 30, 2018
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Jan. 02, 2022
USD ($)
Jan. 03, 2022
USD ($)
Mar. 31, 2021
USD ($)
Mar. 08, 2021
USD ($)
Aug. 31, 2018
USD ($)
Aug. 21, 2018
Debt Instrument [Line Items]                        
Additional paid-in capital         $ 9,555,000,000 $ 9,207,000,000            
Retained earnings (accumulated deficit)         (19,000,000) 1,142,000,000            
Purchase obligation         290,000,000              
Cumulative Effect, Period of Adoption, Adjustment | ASU 2020-06                        
Debt Instrument [Line Items]                        
Additional paid-in capital               $ (93,000,000)        
Convertible debt               43,000,000        
Retained earnings (accumulated deficit)               61,000,000        
Deferred tax assets, net               $ 11,000,000        
Term Notes                        
Debt Instrument [Line Items]                        
Interest expense recognized         $ 74,000,000 21,000,000 $ 14,000,000          
Net proceeds from issuance, after deducting offering expenses payable   $ 991,000,000 $ 992,000,000                  
Redemption price, percentage         100.00%              
Term Notes | Term Notes Due 2023                        
Debt Instrument [Line Items]                        
Interest rate on convertible senior notes     0.55%                  
Principal amount         $ 0 500,000,000     $ 500,000,000      
Term Notes | Term Notes Due 2031                        
Debt Instrument [Line Items]                        
Interest rate on convertible senior notes     2.55%                  
Principal amount     $ 500,000,000   500,000,000 500,000,000            
Term Notes | Term Notes Due 2025                        
Debt Instrument [Line Items]                        
Interest rate on convertible senior notes   5.80%                    
Principal amount   $ 500,000,000     500,000,000 500,000,000            
Term Notes | Term Notes Due 2027                        
Debt Instrument [Line Items]                        
Interest rate on convertible senior notes   5.75%                    
Principal amount   $ 500,000,000     500,000,000 500,000,000            
Convertible Senior Notes                        
Debt Instrument [Line Items]                        
Interest expense recognized         $ 2,000,000 $ 3,000,000 $ 29,000,000          
Convertible Senior Notes | 2023 Notes                        
Debt Instrument [Line Items]                        
Interest rate on convertible senior notes                       0.00%
Principal amount                     $ 750,000,000  
Debt conversion ratio       0.0021845                
Effective interest rate used to measure fair value of convertible senior note                     3.70%  
Debt, fair value                     $ 624,000,000  
Additional paid in capital, before tax                     126,000,000  
Additional paid-in capital                     $ 93,000,000  
Line of Credit | Revolving Credit Facility | Credit Agreement                        
Debt Instrument [Line Items]                        
Maximum borrowing capacity $ 750,000,000                      
Debt instrument term 5 years                      
Line of Credit | Swingline Borrowings | Credit Agreement                        
Debt Instrument [Line Items]                        
Maximum borrowing capacity $ 40,000,000                      
Debt instrument, number of one year extensions | one_year_extension 2                      
Debt instrument, extension term 1 year                      
Line of Credit | Letter of Credit | Credit Agreement                        
Debt Instrument [Line Items]                        
Maximum borrowing capacity $ 50,000,000                      
Unsecured Debt | Credit Agreement                        
Debt Instrument [Line Items]                        
Debt instrument, face amount, optional increase in additional borrowings                   $ 250,000,000    
Debt instrument, covenant, minimum debt to EBITDA ratio         3.50              
Debt instrument, covenant, minimum debt to EBITDA ratio upon consummation of acquisition         4.00              
Unsecured Debt | Credit Agreement | Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate                        
Debt Instrument [Line Items]                        
Debt instrument, basis spread on variable rate 0.10%                      
v3.24.0.1
Debt and Other Commitments - Schedule of Maturities of Operating Lease Liabilities (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Debt Disclosure [Abstract]    
2024 $ 117  
2025 117  
2026 115  
2027 107  
2028 89  
Thereafter 385  
Total remaining lease payments 930  
Less: imputed interest (157)  
Total operating lease liabilities 773  
Less: current portion (86) $ (76)
Long-term operating lease liabilities $ 687 $ 744
Weighted-average remaining lease term 8 years 9 months 18 days  
Weighted-average discount rate 4.20%  
Lease payments for leases not yet commenced $ 60  
v3.24.0.1
Debt and Other Commitments - Schedule of Lease Costs (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Debt Disclosure [Abstract]      
Operating lease costs $ 116 $ 112 $ 99
Sublease income (20) (20) (16)
Variable lease costs 27 20 21
Total lease costs $ 123 $ 112 $ 104
v3.24.0.1
Stockholders' Equity - Narrative (Details) - 2015 Stock Plan - shares
shares in Millions
6 Months Ended
Jul. 02, 2023
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Shares authorized (in shares) 8.0  
Shares available for issuance   8.2
v3.24.0.1
Stockholders' Equity - Narrative - Restricted Stock (Details) - award
12 Months Ended
Dec. 31, 2023
Jan. 02, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Number of PSU awards 2  
RSU    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share based compensation vesting performance period 4 years  
PSU    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share based compensation vesting performance period 3 years 3 years
Market Based Performance Stock Units    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share-based compensation arrangement by share-based payment award, maximum award payout 175.00%  
v3.24.0.1
Stockholders' Equity - Schedule of Restricted Stock Activity and Related Information (Details) - $ / shares
shares in Thousands
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
RSU      
Stock Units      
Outstanding at period start (in shares) 1,611,000 1,130,000 1,721,000
Awarded (in shares) (2,032,000) (1,370,000) (259,000)
Vested (in shares) (987,000) (707,000) (606,000)
Cancelled (in shares) (458,000) (182,000) (244,000)
Outstanding at period end (in shares) 2,198,000 1,611,000 1,130,000
Weighted-Average Grant- Date Fair Value per Share      
Outstanding at period start (in dollars per share) $ 311.23 $ 345.66 $ 313.35
Awarded (in dollars per share) 195.94 302.52 438.46
Vested (in dollars per share) 268.08 341.56 303.08
Cancelled (in dollars per share) 253.52 341.14 321.93
Outstanding at period end (in dollars per share) $ 236.32 $ 311.23 $ 345.66
RSU | GRAIL Inc      
Stock Units      
Awarded (in shares)     (59)
PSU      
Stock Units      
Outstanding at period start (in shares) 74 328 0
Awarded (in shares) (39) (108) (456)
Vested (in shares) 0 (99) (72)
Cancelled (in shares) (113) (47) (56)
Outstanding at period end (in shares) 0 74 328
Weighted-Average Grant- Date Fair Value per Share      
Outstanding at period start (in dollars per share) $ 446.74 $ 466.42  
Awarded (in dollars per share) 239.98 479.85 $ 471.63
Vested (in dollars per share) 0 492.55 492.55
Cancelled (in dollars per share) 299.98 411.78 475.38
Outstanding at period end (in dollars per share) $ 0 $ 446.74 $ 466.42
Market Based Performance Stock Units      
Weighted-Average Grant- Date Fair Value per Share      
Share-based compensation arrangement by share-based payment award, granted with TSR market condition, number 129    
v3.24.0.1
Stockholders' Equity - Schedule of Pre-tax Intrinsic Values and Total Fair Value of Vested Restricted Stock (Details) - USD ($)
shares in Thousands, $ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
RSU      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax intrinsic value of outstanding restricted stock: $ 306 $ 326 $ 430
Fair value of restricted stock vested: 122 162 247
PSU      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax intrinsic value of outstanding restricted stock: 0 15 125
Fair value of restricted stock vested: $ 0 $ 49 $ 35
Liability Classified Restricted Stock Units      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Liability-classified awards (in shares) 557    
v3.24.0.1
Stockholders' Equity - Schedule of Stock Option Activity Under all Stock Option Plans (Details) - $ / shares
shares in Thousands
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Options      
Options and Performance Stock Options      
Outstanding at period start (in shares) 187 8 10
Granted (in shares)   180 0
Exercised (in shares) (8) (1) (2)
Cancelled (in shares) (144)   0
Outstanding at period end (in shares) 35 187 8
Exercisable at period end (in shares)   9  
Weighted-Average Exercise Price      
Outstanding at period start (in dollars per share) $ 319.72 $ 66.42 $ 59.11
Granted (in dollars per share)   330.25 0
Exercised (in dollars per share) 71.09 6.55 20.06
Cancelled (in dollars per share) 330.25   0
Outstanding at period end (in dollars per share) $ 330.25 319.72 $ 66.42
Exercisable at period end (in dollars per share)   $ 330.25  
Performance Stock Options      
Options and Performance Stock Options      
Outstanding at period start (in shares) 17 17 0
Granted (in shares)   0 48,000
Exercised (in shares) (1) 0 (21,000)
Cancelled (in shares) 0   (10,000)
Outstanding at period end (in shares) 16 17 17
Exercisable at period end (in shares)   0  
Weighted-Average Exercise Price      
Outstanding at period start (in dollars per share) $ 85.54 $ 85.54 $ 0
Granted (in dollars per share)   0 86.73
Exercised (in dollars per share) 16.69 0 86.72
Cancelled (in dollars per share) 0   89.63
Outstanding at period end (in dollars per share) $ 87.74 85.54 $ 85.54
Exercisable at period end (in dollars per share)   $ 0  
v3.24.0.1
Stockholders' Equity - Narrative - Stock Options (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Dec. 29, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Aggregate intrinsic value of options outstanding $ 0      
Share price (in dollars per share)       $ 139.24
Total intrinsic value of options exercised $ 1 $ 0 $ 1  
Weighted average remaining life in years of options exercisable 5 years 2 months 12 days      
Performance Stock Options        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Aggregate intrinsic value of options outstanding $ 1      
Total intrinsic value of options exercised $ 0 $ 0 $ 6  
Weighted average remaining life in years of options exercisable 10 years      
v3.24.0.1
Stockholders' Equity - Narrative - Liability-Classified Awards (Details) - USD ($)
12 Months Ended
Jan. 01, 2023
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense   $ 380,000,000 $ 366,000,000 $ 941,000,000
Unrecognized compensation cost   $ 496,000,000    
Weighted-average period of unrecognized compensation cost   2 years 3 months 18 days    
Liability-Based Awards        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Award expiration period   4 years    
Share based compensation vesting performance period   4 years    
Share-based compensation expense $ 0 $ 95,000,000 67,000,000 $ 11,000,000
Unrecognized compensation cost   $ 237,000,000    
Weighted-average period of unrecognized compensation cost   2 years 6 months    
Aggregated potential value $ 78,000,000   $ 78,000,000  
v3.24.0.1
Stockholders' Equity - Schedule of Cash-Based Equity Incentive Award Activity (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Share-Based Compensation Arrangement By Share-Based Payment Award, Liability-Classified Awards [Roll Forward]      
Change in fair value $ (8) $ 23 $ 8
Liability-classified equity incentive awards 55 36  
Liability-Based Awards      
Share-Based Compensation Arrangement By Share-Based Payment Award, Liability-Classified Awards [Roll Forward]      
Beginning balance 293 184 0
Granted 116 168 218
Cancelled (32) (41) (42)
Vested and paid in cash (77) (41)  
Ending balance $ 292 293 $ 184
Liability-classified equity incentive awards   $ 55  
v3.24.0.1
Stockholders' Equity - Narrative - Employee Stock Purchase Plan (Details) - ESPP - Employee Stock - shares
shares in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
ESPP number of shares reserved for issuance (in shares) 15.5    
Specified percentage of the fair market value of the common stock on the first or last day of the offering period whichever is lower at which stock is purchased 85.00%    
Shares authorized (in shares) 0.4 0.3 0.2
Shares available for issuance (in shares) 12.4 12.8  
v3.24.0.1
Stockholders' Equity - Narrative - Share Repurchases (Details) - Common Stock - USD ($)
shares in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Feb. 05, 2020
Class of Stock [Line Items]      
Repurchase of common shares (in shares) 0.0 0.0  
Dollar amount remaining in authorized stock repurchase program $ 15,000,000    
Stock repurchase program authorized amount     $ 750,000,000
v3.24.0.1
Stockholders' Equity - Schedule of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected dividends 0.00%    
Unrecognized compensation cost related to stock options, restricted stock, and ESPP shares granted to date $ 496    
Weighted-average period of unrecognized compensation cost related to stock options, restricted stock, and ESPP shares granted to date 2 years 3 months 18 days    
Employee Stock      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk-free interest rate, minimum 0.78% 0.06% 0.06%
Risk-free interest rate, maximum 5.54% 2.98% 0.12%
Expected volatility, minimum 41.00% 37.00% 37.00%
Expected volatility, maximum 51.00% 51.00% 47.00%
Expected dividends   0.00% 0.00%
Weighted-average grant-date fair value per share (in dollars per share) $ 49.87 $ 50.22 $ 134.47
Employee Stock | Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 6 months 6 months 6 months
Employee Stock | Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 1 year 1 month 6 days 1 year 1 year
v3.24.0.1
Stockholders' Equity - Schedule of Share-Based Compensation Expense for all Stock Awards (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes $ 380 $ 366 $ 941
Related income tax benefits (87) (83) (64)
Share-based compensation expense, net of taxes 293 283 877
Cost of product revenue      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 29 26 23
Cost of service and other revenue      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 7 6 4
Research and development      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes 155 153 276
Selling, general and administrative      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense, before taxes $ 189 $ 181 $ 638
v3.24.0.1
Stockholders' Equity - Narrative - Share-Based Compensation (Details)
$ in Millions
1 Months Ended 12 Months Ended
Feb. 28, 2021
USD ($)
employee
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Jan. 02, 2022
USD ($)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense, before taxes   $ 380 $ 366 $ 941
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense, before taxes   155 153 276
Selling, general and administrative        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense, before taxes   189 181 638
GRAIL Inc        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based payment arrangement, accelerated cost       615
Replacement Awards | GRAIL Inc        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based payment arrangement, accelerated cost       615
Share-based compensation expense, before taxes   $ 2 $ 10 24
Replacement Awards | GRAIL Inc | Research and development        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based payment arrangement, accelerated cost       167
Replacement Awards | GRAIL Inc | Selling, general and administrative        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based payment arrangement, accelerated cost       $ 448
PSU        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share based compensation vesting performance period   3 years   3 years
Performance Shares, Granted In 2019        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of employees effected by modification | employee 52      
Incremental share-based compensation cost $ 41      
Performance Shares, Granted In 2020        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of employees effected by modification | employee 72      
Incremental share-based compensation cost $ 65      
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Accounts Receivable (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Trade accounts receivable, gross $ 741 $ 675
Allowance for credit losses (7) (4)
Total accounts receivable, net $ 734 $ 671
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Inventory (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Raw materials $ 276 $ 247
Work in process 402 386
Finished goods 30 28
Inventory, gross 708 661
Inventory reserve (121) (93)
Total inventory, net $ 587 $ 568
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Property and Equipment (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 2,145 $ 2,053
Accumulated depreciation (1,138) (962)
Total property and equipment, net 1,007 1,091
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 803 759
Machinery and equipment    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 684 644
Computer hardware and software    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 463 424
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 55 50
Buildings    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 44 44
Construction in progress    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 96 $ 132
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Narrative - Property and Equipment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Non-cash expenditures included in property and equipment, net $ 12 $ 16 $ 17
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Accrued Liabilities (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Legal contingencies $ 484 $ 473
Contract liabilities, current portion 252 245
Accrued compensation expenses(2) 223 188
Accrued taxes payable 79 97
Operating lease liabilities, current portion 86 76
Liability-classified equity incentive awards 55 36
Other, including warranties 146 117
Total accrued liabilities $ 1,325 $ 1,232
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Long-term operating lease liabilities Long-term operating lease liabilities
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Changes in Reserve for Product Warranties (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Movement in Standard and Extended Product Warranty Accrual, Increase (Decrease) [Roll Forward]      
Balance as of beginning of period $ 18 $ 22 $ 13
Additions charged to cost of product revenue 42 23 33
Repairs and replacements (39) (27) (24)
Balance as of end of period $ 21 $ 18 $ 22
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Pre-Tax Restructuring Charge (Details)
$ in Millions
12 Months Ended
Dec. 31, 2023
USD ($)
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges $ 152
Selling, general and administrative  
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges 122
Research and development  
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges 24
Employee separation costs  
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges 48
Asset Impairment Charges  
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges 100
Other Costs  
Restructuring Cost and Reserve [Line Items]  
Total restructuring charges $ 4
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Narrative - Restructuring (Details)
$ in Millions
12 Months Ended
Dec. 31, 2023
USD ($)
Restructuring Cost and Reserve [Line Items]  
Right-of-use asset impairment $ 38
Right-of-use assets and leasehold improvements 21
CALIFORNIA  
Restructuring Cost and Reserve [Line Items]  
Right-of-use assets and leasehold improvements 136
Leasehold improvements  
Restructuring Cost and Reserve [Line Items]  
Right-of-use asset impairment 16
Right-of-use assets and leasehold improvements $ 22
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Pre-Tax Charges and Total Costs (Details)
$ in Millions
12 Months Ended
Dec. 31, 2023
USD ($)
Restructuring Cost and Reserve [Line Items]  
Expense recorded in 2023 $ 52
Cash paid during 2023 (34)
Amounts recorded in accrued liabilities as of YTD 2023 18
Estimated total restructuring costs to still be incurred 8
Employee separation costs  
Restructuring Cost and Reserve [Line Items]  
Expense recorded in 2023 48
Cash paid during 2023 (31)
Amounts recorded in accrued liabilities as of YTD 2023 17
Estimated total restructuring costs to still be incurred 8
Other Costs  
Restructuring Cost and Reserve [Line Items]  
Expense recorded in 2023 4
Cash paid during 2023 (3)
Amounts recorded in accrued liabilities as of YTD 2023 1
Estimated total restructuring costs to still be incurred $ 0
v3.24.0.1
Supplemental Balance Sheet and Statement of Operations Details - Schedule of Other (Expense) Income, Net (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Gain on previously held investment in GRAIL $ 0 $ 0 $ 899
Gain on exchange of GRAIL contingent value rights 0 0 86
Gain (loss) on Helix contingent value right 10 (7) 30
Gain on derivative assets related to terminated acquisition 0 0 26
(Losses) gains on strategic investments, net (40) (122) 18
Other 1 (13) 9
Other (expense) income, net $ (29) $ (142) $ 1,068
v3.24.0.1
Legal Proceedings (Details)
€ in Millions, $ in Millions
3 Months Ended 9 Months Ended 12 Months Ended
Nov. 11, 2023
numberOfSegment
Apr. 02, 2023
Oct. 02, 2022
USD ($)
Dec. 31, 2023
USD ($)
Feb. 02, 2024
lawsuit
Jul. 25, 2023
EUR (€)
Jul. 12, 2023
EUR (€)
Loss Contingencies [Line Items]              
Loss contingency, new claims filed | numberOfSegment 3            
Subsequent Event              
Loss Contingencies [Line Items]              
Number of additional securities | lawsuit         2    
Complete Genomics              
Loss Contingencies [Line Items]              
Payments for legal settlements       $ 325      
Payments for legal settlements, amount allocated to release of past damages claimed       150      
Former gain contingency, recognized in current period       5      
Complete Genomics | License              
Loss Contingencies [Line Items]              
License granted intangible assets     $ 180 $ 180      
Finite-lived intangible assets, remaining amortization period     6 years 6 months 6 years 6 months      
GRAIL              
Loss Contingencies [Line Items]              
Loss contingency accrual       $ 484   € 432 € 432
Loss contingency accrual as a percent of revenues   0.10          
Long-term debt, fine percentage rate       0.055      
v3.24.0.1
Income Taxes - Schedule of (Loss) Income before Income Taxes by Region (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Income Tax Disclosure [Abstract]      
United States $ (1,735) $ (4,942) $ (115)
Foreign 618 606 999
(Loss) income before income taxes $ (1,117) $ (4,336) $ 884
v3.24.0.1
Income Taxes - Schedule of Provision for Income Taxes (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Current:      
Federal $ (5) $ (11) $ 54
State 6 27 37
Foreign 77 75 107
Total current provision 78 91 198
Deferred:      
Federal (13) 40 (50)
State (26) (47) (23)
Foreign 5 (16) (3)
Total deferred benefit (34) (23) (76)
Total tax provision $ 44 $ 68 $ 122
v3.24.0.1
Income Taxes - Schedule of Reconciliation of Provision for (Loss) Income Taxes to Amount Computed by Applying the Federal Statutory Rate (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Income Tax Disclosure [Abstract]      
Tax at federal statutory rate $ (235) $ (911) $ 186
State, net of federal benefit (16) (9) 13
Research and other credits (42) (46) (23)
Change in valuation allowance 48 62 33
Impact of R&D expense capitalization 86 87 0
Impact of net operating losses on GILTI and U.S. foreign tax credits 61 60 0
Impact of foreign operations (50) (81) (80)
Impact of foreign derived intangible income (FDII) deduction 1 (1) (12)
Stock compensation 31 20 (10)
Officer compensation (4) 4 13
Accrual of European Commission fine 3 96 0
Goodwill impairment 149 822 0
Impact of acquisition related items 8 (27) (16)
Other 4 (8) 18
Total tax provision $ 44 $ 68 $ 122
v3.24.0.1
Income Taxes - Narrative (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Tax Credit Carryforward [Line Items]      
Valuation allowance on deferred tax assets $ 251 $ 203  
Deferred tax liability for undistributed foreign earnings 25    
Uncertain tax positions that would reduce annual effective tax rate, if recognized 156 124  
Potential interest penalties (income) on uncertain tax positions 2 (3) $ 1
Liability recorded for potential interest and penalties 6 3  
Tax Year 2017      
Tax Credit Carryforward [Line Items]      
Undistributed earnings of foreign subsidiaries 1,855    
Federal      
Tax Credit Carryforward [Line Items]      
Tax credit carryforwards 105    
Federal | IRS      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 860    
State      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 1,874    
Tax credit carryforwards 223    
Foreign | Singapore      
Tax Credit Carryforward [Line Items]      
Decrease to the provision for income taxes $ 75 $ 56 $ 82
Increase to net income per diluted share (in dollars per share) $ 0.47 $ 0.35 $ 0.55
v3.24.0.1
Income Taxes - Schedule of Significant Components of Deferred Tax Assets and Liabilities (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Deferred tax assets:    
Net operating losses $ 392 $ 408
Tax credits 211 157
Other accruals and reserves 49 40
Stock compensation 15 20
Capitalized U.S. R&D expenses 158 97
Other amortization 115 247
Operating lease liabilities 146 156
Property and equipment 4 0
Investments 7 5
Other 56 38
Total gross deferred tax assets 1,153 1,168
Valuation allowance on deferred tax assets (251) (203)
Total deferred tax assets 902 965
Deferred tax liabilities:    
Purchased intangible amortization (734) (800)
Property and equipment 0 (11)
Operating lease right-of-use assets (88) (112)
Other (25) (18)
Total deferred tax liabilities (847) (941)
Deferred tax assets, net $ 55 $ 24
v3.24.0.1
Income Taxes - Schedule of the Gross Amount of Uncertain Tax Positions (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]      
Balance at beginning of year $ 153 $ 131 $ 80
Increases related to prior year tax positions 27 12 19
Decreases related to prior year tax positions (2) (3) (1)
Increases related to current year tax positions 42 42 39
Decreases related to lapse of statute of limitations (10) (29) (6)
Balance at end of year $ 210 $ 153 $ 131
v3.24.0.1
Employee Benefit Plans (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Matching contributions $ 36 $ 30 $ 26
Deferred Compensation Plan      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Employer contribution vesting percent upon the occurrence of participant's disability, death or retirement or change in control of the Company 100.00%    
Deferred compensation plan assets $ 61 52  
Deferred compensation liability $ 59 $ 51  
Deferred Compensation Plan | Senior Level Employee      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Percent of base salary available for contribution to the deferred compensation plan 60.00%    
Percent of all other forms of compensation available for contribution to the deferred compensation plan 100.00%    
Deferred Compensation Plan | Director      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Percent of all other forms of compensation available for contribution to the deferred compensation plan 100.00%    
v3.24.0.1
Segments and Geographic Data - Narrative (Details)
12 Months Ended
Dec. 31, 2023
segment
Segment Reporting [Abstract]  
Number of reportable segment 2
v3.24.0.1
Segments and Geographic Data - Schedule of Operating Performance and Assets by Segment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Jan. 01, 2023
Jan. 02, 2022
Segment Reporting Information [Line Items]      
Consolidated revenue $ 4,504 $ 4,584 $ 4,526
Consolidated depreciation and amortization 432 394 251
Consolidated (loss) income from operations (1,069) (4,179) (123)
Consolidated capital expenditures 195 286 208
Operating Segments | Core Illumina      
Segment Reporting Information [Line Items]      
Consolidated revenue 4,438 4,553 4,519
Consolidated depreciation and amortization 273 240 200
Consolidated (loss) income from operations 552 481 808
Consolidated capital expenditures 183 262 201
Operating Segments | GRAIL      
Segment Reporting Information [Line Items]      
Consolidated revenue 93 55 12
Consolidated depreciation and amortization 159 154 51
Consolidated (loss) income from operations (1,621) (4,657) (931)
Consolidated capital expenditures 13 24 8
Eliminations      
Segment Reporting Information [Line Items]      
Consolidated revenue (27) (24) (5)
Consolidated (loss) income from operations 0 (3)  
Consolidated capital expenditures $ (1) $ 0 $ (1)
v3.24.0.1
Segments and Geographic Data - Schedule of Net Long-lived Assets Consisting of Property and Equipment (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Jan. 01, 2023
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total net long-lived assets $ 1,551 $ 1,744
United States    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total net long-lived assets 1,040 1,237
Singapore    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total net long-lived assets 298 290
United Kingdom    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total net long-lived assets 136 149
Other countries    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total net long-lived assets $ 77 $ 68