UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No.    1)*

Trillium Therapeutics Inc.
(Name of Issuer)
Common Shares, no par value
(Title of Class of Securities)
89620X506
(CUSIP Number)
December 31, 2020
(Date of Event which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
☐ Rule 13d-1(b)
☒ Rule 13d-1(c)
☐ Rule 13d-1(d)
 
*	The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.	
The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

Page 2 of 7
CUSIP No. 89620X506

  1  	 	  Name of reporting persons.
 
  Boxer Capital, LLC	
  2	 	  Check the appropriate box if a member of a group. (See instructions).
  (a)  ☐        (b)  ☒
 	
  3	 	  SEC use only.
 	
  4	 	  Citizenship or place of organization.
 
  Delaware	
							
NUMBER OF
SHARES
 BENEFICIALLY 
OWNED BY
EACH
REPORTING
PERSON
WITH:	  	5  	  	  Sole voting power.
 
  -0-	
	  	6	  	  Shared voting power.
 
  -0-	
	  	7	  	  Sole dispositive power.
 
  -0-	
	  	8	  	  Shared dispositive power.
 
  -0-	
							
  9  	 	  Aggregate amount beneficially owned by each reporting person.
 
  -0-	
10	 	  Check box if the aggregate amount in row (9) excludes certain shares (see instructions).
 
  ☐	
11	 	  Percent of class represented by amount in row (9).
 
  0%*	
12	 	  Type of reporting person
 
  OO	

Page 3 of 7
CUSIP No. 89620X506

  1  	 	  Name of reporting persons.
 
  Boxer Asset Management Inc.	
  2	 	  Check the appropriate box if a member of a group. (See instructions).
  (a)  ☐        (b)  ☒
 	
  3	 	  SEC use only.
 	
  4	 	  Citizenship or place of organization.
 
  Bahamas	
							
NUMBER OF
SHARES
 BENEFICIALLY 
OWNED BY
EACH
REPORTING
PERSON
WITH:	  	5  	  	  Sole voting power.
 
  -0-	
	  	6	  	  Shared voting power.
 
  -0-	
	  	7	  	  Sole dispositive power.
 
  -0-	
	  	8	  	  Shared dispositive power.
 
  -0-	
							
  9  	 	  Aggregate amount beneficially owned by each reporting person.
 
  -0-	
10	 	  Check box if the aggregate amount in row (9) excludes certain shares (see instructions).
 
  ☐	
11	 	  Percent of class represented by amount in row (9).
 
  0%	
12	 	  Type of reporting person
 
  CO	

Page 4 of 7
CUSIP No. 89620X506

  1  	 	  Name of reporting persons.
 
  Joe Lewis	
  2	 	  Check the appropriate box if a member of a group. (See instructions).
  (a)  ☐        (b)  ☒
 	
  3	 	  SEC use only.
 	
  4	 	  Citizenship or place of organization.
 
  United Kingdom	
							
NUMBER OF
SHARES
 BENEFICIALLY 
OWNED BY
EACH
REPORTING
PERSON
WITH:	  	5  	  	  Sole voting power.
 
  -0-	
	  	6	  	  Shared voting power.
 
  -0-	
	  	7	  	  Sole dispositive power.
 
  -0-	
	  	8	  	  Shared dispositive power.
 
  -0-	
							
  9  	 	  Aggregate amount beneficially owned by each reporting person.
 
  -0-	
10	 	  Check box if the aggregate amount in row (9) excludes certain shares (see instructions).
 
  ☐	
11	 	  Percent of class represented by amount in row (9).
 
  0%	
12	 	  Type of reporting person
 
  IN	

Page 5 of 7
 
This Amendment No. 1 (“Amendment No. 1”) amends and supplements the statement on Schedule 13G filed on February 3, 2020 (the “Original Filing”) by Boxer Capital, LLC (“Boxer Capital”), Boxer Asset Management Inc. (“Boxer Management”) and Joe Lewis (collectively, the “Reporting Persons”). The Original Filing remains in effect except to the extent that it is amended, restated or superseded by information contained in this Amendment No. 1. Capitalized terms used and not defined in this Amendment No. 1 have the meanings set forth in the Original Filing.
 
Item 4.	Ownership.	
 
 	(a)	Amount beneficially owned:	
The Reporting Persons do not own any shares of Common Stock.
 
 	(b)	Percent of class:	
The Reporting Persons do not own any shares of Common Stock.                
 
 	(c)	Number of shares as to which such person has:	
 
 	(i)	Sole power to vote or to direct the vote:	
None of the Reporting Persons has sole power to vote or to direct the vote of any shares of Common Stock.
 
 	(ii)	Shared power to vote or to direct the vote:	
None of the Reporting Persons has shared power to vote or to direct the vote of any shares of Common Stock.
 
 	(iii)	Sole power to dispose or to direct the disposition of:	
None of the Reporting Persons has sole power to dispose or to direct the disposition of any shares of Common Stock.
 
 	(iv)	Shared power to dispose or to direct the disposition of:	
None of the Reporting Persons has shared power to dispose or to direct the disposition of any shares of Common Stock.
 
Item 5.	Ownership of Five Percent or Less of a Class.	
With respect to each Reporting Person:
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ☒.
 
Item 10.	Certification.	
(c) By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

Page 6 of 7
 
Exhibits
 
 	1	Joint Filing Agreement, dated February 3, 2020, among the Reporting Persons, incorporated by reference to Exhibit 1 to the Original Filing.	

SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
February 16, 2021

	 	BOXER CAPITAL, LLC	
			
	 	By:	 	/s/ Aaron I. Davis	
	 	Name:	 	Aaron I. Davis	
	 	Title:	 	Authorized Signatory	
		
	 	BOXER ASSET MANAGEMENT INC.	
			
	 	By:	 	/s/ Jason Callender	
	 	Name:	 	Jason Callender	
	 	Title:	 	Director	
		
	 	JOSEPH C. LEWIS	
		
	 	/s/ Joseph C. Lewis	
	 	Joseph C. Lewis, Individually