FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         	UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
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                      	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	                      	

1. Name and Address of Reporting Person *

Svane Mikkel	2. Issuer Name and Ticker or Trading Symbol

Zendesk, Inc. [ ZEN ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chair and CEO	
(Last)         (First)         (Middle)

989 MARKET STREET	3. Date of Earliest Transaction (MM/DD/YYYY)

2/15/2021		
(Street)

SAN FRANCISCO, CA 94103
(City)       (State)       (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)

 	6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person	

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned	
1.Title of Security
(Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code
(Instr. 8)	4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)	5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)	
			Code	V	Amount	(A) or (D)	Price				
Common Stock 	2/9/2021 	 	G(1)	  V	88800 	D	 (1)	833854 	D 	 	
Common Stock 	2/15/2021 	 	M	  	540 	A	 (2)	834394 	D 	 	
Common Stock 	2/15/2021 	 	F	  	187 (3)	D	$157.20 	834207 	D 	 	
Common Stock 	2/15/2021 	 	M	  	816 	A	 (2)	835023 	D 	 	
Common Stock 	2/15/2021 	 	F	  	283 (3)	D	$157.20 	834740 	D 	 	
Common Stock 	2/15/2021 	 	M	  	525 	A	 (2)	835265 	D 	 	
Common Stock 	2/15/2021 	 	F	  	182 (3)	D	$157.20 	835083 	D 	 	
Common Stock 	2/15/2021 	 	M	  	675 	A	 (2)	835758 	D 	 	
Common Stock 	2/15/2021 	 	F	  	234 (3)	D	$157.20 	835524 	D 	 	
Common Stock 	2/16/2021 	 	M(4)	  	43875 	A	$9.52 	879399 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	5771 	D	$153.6298 (5)	873628 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	11833 	D	$154.452 (6)	861795 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	5600 	D	$155.4857 (7)	856195 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	13606 	D	$156.5796 (8)	842589 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	5133 	D	$157.4674 (9)	837456 	D 	 	
Common Stock 	2/16/2021 	 	S(4)	  	1932 	D	$158.4099 (10)	835524 	D 	 	

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)	
1. Title of Derivate Security
(Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code
(Instr. 8)	5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)	6. Date Exercisable and Expiration Date	7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)	8. Price of Derivative Security
(Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)	
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares					
Restricted Stock Unit 	 (2)	2/15/2021 	 	M 	  	  	540  	 (11)	2/7/2026 	Common Stock 	540.0 	$0 	12411 	D 	 	
Restricted Stock Unit 	 (2)	2/15/2021 	 	M 	  	  	816  	 (12)	2/10/2027 	Common Stock 	816.0 	$0 	29359 	D 	 	
Restricted Stock Unit 	 (2)	2/15/2021 	 	M 	  	  	525  	 (13)	5/9/2024 	Common Stock 	525.0 	$0 	1576 	D 	 	
Restricted Stock Unit 	 (2)	2/15/2021 	 	M 	  	  	675  	 (14)	2/8/2025 	Common Stock 	675.0 	$0 	7426 	D 	 	
Stock Option (Right to Buy) 	$9.52 	2/16/2021 	 	M (4)	  	  	43875  	 (15)	2/13/2024 	Common Stock 	43875.0 	$0 	1535636 	D 	 	

Explanation of Responses:	
(1) 	On February 9, 2021, the reporting person gifted without the receipt of consideration 88,800 shares of Zendesk common stock to a nonprofit public benefit corporation incorporated in California. The reporting person has no pecuniary interest in the corporation and is not the beneficial owner of the securities for purposes of Section 16.	
(2) 	Restricted stock units convert into common stock on a one-for-one basis.	
(3) 	Represents the number of shares withheld by the Issuer in satisfaction of tax withholding obligations in connection with the vesting of the restricted stock units listed in Table II. Such withholding is mandated by an election of the Issuer made in advance and does not represent a discretionary trade by the Reporting Person.	
(4) 	This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by Mikkel Svane on November 23, 2020.	
(5) 	This sale price represents the weighted average sale price of the shares sold ranging from $153.02 to $154.01 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(6) 	This sale price represents the weighted average sale price of the shares sold ranging from $154.03 to $155.00 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(7) 	This sale price represents the weighted average sale price of the shares sold ranging from $155.06 to $156.01 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(8) 	This sale price represents the weighted average sale price of the shares sold ranging from $156.08 to $157.07 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(9) 	This sale price represents the weighted average sale price of the shares sold ranging from $157.10 to $157.97 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(10) 	This sale price represents the weighted average sale price of the shares sold ranging from $158.11 to $158.53 per share. Upon request by the Commission staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.	
(11) 	1/48th of the shares issuable pursuant to the restricted stock units shall vest each month after the vesting commencement date of January 15, 2019, subject to the Reporting Person's continuous service to the Issuer on each such date. Unvested shares are subject to acceleration upon the occurrence of certain events.	
(12) 	1/48th of the shares issuable pursuant to the restricted stock units shall vest each month after the vesting commencement date of February 15, 2020, subject to the Reporting Person's continuous service to the Issuer on each such date. Unvested shares are subject to acceleration upon the occurrence of certain events.	
(13) 	1/48th of the shares issuable pursuant to the restricted stock units shall vest each month after the vesting commencement date of May 15, 2017, subject to the Reporting Person's continuous service to the Issuer on each such date. Unvested shares are subject to acceleration upon the occurrence of certain events.	
(14) 	1/48th of the shares issuable pursuant to the restricted stock units shall vest each month after the vesting commencement date of January 15, 2018, subject to the Reporting Person's continuous service to the Issuer on each such date. Unvested shares are subject to acceleration upon the occurrence of certain events.	
(15) 	The option is early exercisable. 1/60th of the shares vest monthly after the vesting commencement date of February 13, 2014, subject to the Reporting Person's continuous service to the Issuer on each such date. Unvested shares are subject to acceleration upon the occurrence of certain events.	

Reporting Owners	
Reporting Owner Name / Address	Relationships	
	Director	10% Owner	Officer	Other	
Svane Mikkel
989 MARKET STREET
SAN FRANCISCO, CA 94103	X		Chair and CEO		

Signatures		
/s/ Steven Chen via Power-of-Attorney for Mikkel Svane		2/17/2021	
**Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.	
*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).	
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).	
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.	
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.