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SECURITIES AND EXCHANGE COMMISSION
 Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
 (Amendment No. 1)
Cubist Pharmaceuticals, Inc.

(Name of Issuer)

Common Stock, $.001 par value

(Title of Class of Securities)

229678107

(CUSIP Number)
The information required on the remainder of this cover page shall not be deemed to be "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section of the Exchange Act but shall be subject to all other provisions of the Exchange Act.

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SCHEDULE 13G

-------------------------
CUSIP No. 229678107
-------------------------

         1        NAME OF REPORTING PERSON
                  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                           BRISTOL-MYERS SQUIBB COMPANY
                           I.R.S. Employer Identification Number 22-079-0350
------------------------------------------------------------------------------
         2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [_]
                                                                   (b) [X]
------------------------------------------------------------------------------
         3        SEC USE ONLY
------------------------------------------------------------------------------
         4        CITIZENSHIP OR PLACE OF ORGANIZATION
                                            Delaware
------------------------------------------------------------------------------

 NUMBER OF                          5       SOLE VOTING POWER
  SHARES                                           0
BENEFICIALLY                                ----------------------------
 OWNED BY                           6       SHARED VOTING POWER
   EACH                                            0
REPORTING                                   ----------------------------
  PERSON                            7       SOLE DISPOSITIVE POWER
                                                   0
                                            -----------------------------
                                    8       SHARED DISPOSITIVE POWER
                                                   0
------------------------------------------------------------------------------
         9        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                                    0
------------------------------------------------------------------------------
         10       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
                  CERTAIN SHARES                                         [_]
------------------------------------------------------------------------------
         11       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                    0%
------------------------------------------------------------------------------
         12       TYPE OF REPORTING PERSON
                                    CO
------------------------------------------------------------------------------	

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CUSIP NO. 229678107
-------------------------

Item 1(a).  Name of Issuer:
            Cubist Pharmaceuticals, Inc.

Item 1(b).  Address of Issuer's Principal Executive Offices:
            24 Emily Street, Cambridge, Massachusetts 02139

Item 2(a).  Name of Person Filing:
            Bristol-Myers Squibb Company

Item 2(b).  Address of Principal Business Office or, if None, Residence:
            345 Park Avenue, New York, NY 10154

Item 2(c).  Citizenship:
            Delaware

Item 2(d).  Title of Class of Securities:
            Common Stock, $.001 par value per share

Item 2(e).  CUSIP Number:
            229678107

Item 3. If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b),
check whether the person filing is a:

            (a) [_] Broker or dealer registered under Section 15 of the Act;

            (b) [_] Bank as defined in Section 3(a)(6) of the Act;

            (c) [_] Insurance Company as defined in Section 3(a)(19) of the Act;

            (d) [_] Investment Company registered under Section 8 of the
                    Investment Company Act;

            (e) [_] Investment Adviser registered under Section 203 of the
                    Investment Advisers Act of 1940;

            (f) [_] Employee Benefit Plan, Pension Fund which is subject to the
                    provisions of the Employee Retirement Income Security
                    act of 1974 or Endowment Fund; see 13d-1(b)(1)(ii)(F);

            (g) [_] Parent Holding Company, in accordance with Rule
                    13d-1(b)(i)(G); see Item 7;

            (h) [_] Group, in accordance with Rule 13d-1(b)(1)(ii)(H).	

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-------------------------
CUSIP NO. 229678107
-------------------------

Item 4.  Ownership.

                  If the percent of the class owned, as of December 31 of the
year covered by the statement, or as of the last day of any month described in
Rule 13d-1 (b)(2), if applicable, exceeds five percent, provide the following
information as of that date and identify those shares which there is a right to
acquire.
                  (a)   Amount beneficially owned:
                                        0
                        -------------------------------------------------------
                  (b)   Percent of class:
                                        0%
                        -------------------------------------------------------
                  (c)   Number of shares as to which such person has:
                  (i)   Sole power to vote or to direct the vote         0     ,
                                                                      ----------
                  (ii)  Shared power to vote or to direct the vote       0     ,
                                                                      ----------
                  (iii) Sole power to dispose or to direct the disposition of
                                                                         0     ,
                                                                      ----------
                  (iv)  Shared power to dispose or to direct the disposition of
                                                                         0     ,
                                                                      ----------
Item 5.  Ownership of Five Percent or Less of a Class.

                  If this statement is being filed to report the fact that as of
                  the date hereof the reporting person has ceased to be the
                  beneficial owner of more than five percent of the class of
                  securities, check the following [X].

Item 6.  Ownership of More Than Five Percent on Behalf of Another Person.

                  Not Applicable.

Item 7.  Identification and Classification of the Subsidiary Which Acquired
         the Security Being Reported on by the Parent Holding Company.

                  Not Applicable.

Item 8.  Identification and Classification of Members of the Group.

                  Not Applicable.

Item 9.  Notice of Dissolution of Group.

                  Not Applicable.	

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CUSIP NO. 229678107
-------------------------

Item 10. Certification.

                  By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were acquired in the ordinary
course of business and were not acquired for the purpose of and do not have the
effect of changing or influencing the control of the issuer of such securities
and were not acquired in connection with or as a participant in any transaction
having such purpose or effect.	

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SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete and correct.

Dated: February 11, 2000                        BRISTOL-MYERS SQUIBB COMPANY
       -------------------

                                                By: /s/ Robert E. Ewers, Jr.
                                                    ------------------------
                                                    Robert E. Ewers, Jr.
                                                    Senior Counsel and
                                                    Assistant Secretary